Lista de obras - Matthew J. Sweet - Dominio Público Uruguay

A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations

artículo científico publicado en 2006

A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice

article

A sprinkle of salt in the pressure cooker of innate immunity and inflammation

artículo científico publicado en 2020

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

artículo científico publicado en 2012

An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.

artículo científico publicado en 2016

An alloy of zinc and innate immunity: galvanizing host defence against infection

scientific article published on 25 September 2020

An antioxidant role for catecholate siderophores in Salmonella.

artículo científico publicado en 2013

An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation.

artículo científico publicado en 2013

Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell death

artículo científico publicado en 2015

B cells do not take up bacterial DNA: an essential role for antigen in exposure of DNA to toll-like receptor-9.

artículo científico publicado en 2010

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

artículo científico publicado en 2009

CAT2-mediated L-arginine transport and nitric oxide production in activated macrophages.

artículo científico publicado en 1999

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB.

artículo científico publicado en 2013

Co-transcriptomic Analysis by RNA Sequencing to Simultaneously Measure Regulated Gene Expression in Host and Bacterial Pathogen

artículo científico publicado en 2016

Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages

artículo científico publicado en 2008

Complex Multilevel Control of Hemolysin Production by Uropathogenic Escherichia coli

scientific article published on 01 October 2019

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

artículo científico publicado en 2012

Copper redistribution in murine macrophages in response to Salmonella infection

artículo científico publicado en 2012

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

artículo científico publicado en 2011

Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1.

artículo científico publicado en 2013

Dead cells certainly do matter, particularly when they can speak from the grave

artículo científico publicado en 2010

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice

artículo científico publicado en 2015

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

artículo científico publicado en 2015

Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.

artículo científico publicado en 2010

Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP.

artículo científico publicado en 2017

Differences in the repertoire, regulation and function of Toll-like Receptors and inflammasome-forming Nod-like Receptors between human and mouse.

artículo científico

Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis

artículo científico publicado en 2015

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS.

artículo científico publicado en 2010

Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1.

artículo científico publicado en 2009

Expression analysis of G Protein-Coupled Receptors in mouse macrophages

artículo científico publicado en 2008

For when bacterial infections persist: Toll-like receptor-inducible direct antimicrobial pathways in macrophages.

artículo científico publicado en 2018

Frontline Science: LPS-inducible SLC30A1 drives human macrophage-mediated zinc toxicity against intracellular Escherichia coli

artículo científico publicado en 2020

G-protein-coupled receptor expression, function, and signaling in macrophages

artículo científico publicado en 2007

Genetic control of the innate immune response

artículo científico publicado en 2003

Genome-Wide Discovery of Genes Required for Capsule Production by Uropathogenic Escherichia coli

artículo científico publicado en 2017

Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP.

artículo científico publicado en 2018

Group A streptococcal pharyngitis: immune responses involved in bacterial clearance and GAS-associated immunopathologies

artículo científico publicado en 2017

HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation.

artículo científico

HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks

artículo científico publicado en 2012

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

scientific journal article

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi.

artículo científico publicado en 2015

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

article

Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages.

artículo científico publicado en 2015

Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages

artículo científico publicado en 2013

Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment

article

Histone deacetylase inhibitors in inflammatory disease.

artículo científico publicado en 2009

Histone deacetylases as regulators of inflammation and immunity ⬇️

artículo científico publicado el 12 de mayo de 2011

Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases

artículo científico publicado en 2016

Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis

scientific article published on 01 June 2019

Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides

artículo científico publicado en 2011

In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis.

artículo científico publicado en 2017

Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a.

artículo científico publicado en 2013

Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

artículo científico publicado en 2015

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic type 2 inflammation

scientific article published on 17 August 2019

Inhibitors selective for HDAC6 in enzymes and cells ⬇️

artículo científico publicado el 12 de octubre de 2010

Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: A ticking time bomb in ageing

artículo científico

Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells.

artículo científico publicado en 2014

Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion

artículo científico publicado en 2018

Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages

artículo científico publicado en 2011

LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action

artículo científico publicado en 2005

LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression

artículo científico publicado en 2006

Lipopolysaccharide promotes Drp1-dependent mitochondrial fission and associated inflammatory responses in macrophages

artículo científico publicado en 2020

Lysine Deacetylases and Regulated Glycolysis in Macrophages.

artículo científico publicado en 2018

Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis

artículo científico publicado en 2011

Macrophage secretory products induce an inflammatory phenotype in hepatocytes

artículo científico publicado en 2012

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

scientific article published on 01 October 2020

Mechanism of Bacterial Interference with TLR4 Signaling by Brucella Toll/Interleukin-1 Receptor Domain-containing Protein TcpB

artículo científico publicado en 2014

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

artículo científico publicado en 2013

Minocycline Prevents the Development of Mechanical Allodynia in Mouse Models of Vincristine-Induced Peripheral Neuropathy

artículo científico publicado en 2019

Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells

artículo científico publicado en 2021

Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps

artículo científico publicado en 2018

Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.

artículo científico publicado en 1994

Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

artículo científico publicado en 2011

PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages

artículo científico publicado en 2007

Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion ⬇️

artículo científico publicado en 2010

Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C

artículo científico publicado en 2012

Protective role for Toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E-deficient mice

artículo científico publicado en 2014

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling

artículo científico publicado en 2014

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.

artículo científico publicado en 2016

Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation

artículo científico publicado en 2014

Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4

article

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages.

artículo científico publicado en 2018

Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages

artículo científico publicado en 2008

SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages

artículo científico publicado en 2017

SCIMP is a universal Toll-like receptor adaptor in macrophages

scientific article published on 29 August 2019

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages

artículo científico publicado en 2016

Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling.

artículo científico publicado en 2008

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

artículo científico publicado en 2014

Signal integration between IFNgamma and TLR signalling pathways in macrophages

artículo científico publicado en 2006

Small GTPase Rab8a-recruited Phosphatidylinositol 3-Kinase γ Regulates Signaling and Cytokine Outputs from Endosomal Toll-like Receptors.

artículo científico publicado en 2017

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli

artículo científico publicado en 2015

T1/ST2--an IL-1 receptor-like modulator of immune responses.

artículo científico publicado en 2004

TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes

artículo científico publicado en 2015

TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium

artículo científico publicado en 2008

TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target

artículo científico publicado en 2016

The Australian Toll-way gets the Nod--meeting report of TLROZ 2007: pattern recognition receptors in immunity and disease, Melbourne, Australia, 16-18th May 2007.

artículo científico publicado en 2007

The E3 ubiquitin ligase RNF144B is LPS-inducible in human, but not mouse, macrophages and promotes inducible IL-1β expression

artículo científico publicado en 2016

The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins

artículo científico publicado en 2013

The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host-pathogen interactions

artículo científico publicado en 2015

The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection.

scientific article published on 21 October 2016

The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes

artículo científico publicado en 2011

The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer

artículo científico publicado en 2012

The mammalian PYHIN gene family: phylogeny, evolution and expression

artículo científico publicado en 2012

The multi-copper-ion oxidase CueO of Salmonella enterica serovar Typhimurium is required for systemic virulence

artículo científico publicado en 2010

The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists

artículo científico publicado en 2016

The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge

artículo científico publicado en 2014

The nicer side of innate immunity: Wound healing and tissue regeneration

artículo científico publicado en 2017

The role of H4 flagella in Escherichia coli ST131 virulence

artículo científico publicado en 2015

The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized

artículo científico publicado en 2013

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair.

artículo científico publicado en 2016

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

artículo científico publicado en 2009

Towards isozyme-selective HDAC inhibitors for interrogating disease.

artículo científico publicado en 2012

Towards selective lysophospholipid GPCR modulators

artículo científico publicado en 2014

Transcriptional network dynamics in macrophage activation

artículo científico

Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis

artículo científico publicado en 2014

Uropathogenic Escherichia coli Engages CD14-Dependent Signaling to Enable Bladder-Macrophage-Dependent Control of Acute Urinary Tract Infection.

artículo científico publicado en 2015

Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection

artículo científico publicado en 2013

Uropathogenic employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

article

Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer

artículo científico publicado en 2015

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

artículo científico publicado en 2019

pTRAPs: Transmembrane adaptors in innate immune signaling.

artículo científico publicado en 2018

Lista de obras de Matthew J. Sweet

A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations

A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice

A sprinkle of salt in the pressure cooker of innate immunity and inflammation

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.

An alloy of zinc and innate immunity: galvanizing host defence against infection

An antioxidant role for catecholate siderophores in Salmonella.

An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation.

Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell death

B cells do not take up bacterial DNA: an essential role for antigen in exposure of DNA to toll-like receptor-9.

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

CAT2-mediated L-arginine transport and nitric oxide production in activated macrophages.

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB.

Co-transcriptomic Analysis by RNA Sequencing to Simultaneously Measure Regulated Gene Expression in Host and Bacterial Pathogen

Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages

Complex Multilevel Control of Hemolysin Production by Uropathogenic Escherichia coli

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

Copper redistribution in murine macrophages in response to Salmonella infection

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1.

Dead cells certainly do matter, particularly when they can speak from the grave

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.

Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP.

Differences in the repertoire, regulation and function of Toll-like Receptors and inflammasome-forming Nod-like Receptors between human and mouse.

Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS.

Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1.

Expression analysis of G Protein-Coupled Receptors in mouse macrophages

For when bacterial infections persist: Toll-like receptor-inducible direct antimicrobial pathways in macrophages.

Frontline Science: LPS-inducible SLC30A1 drives human macrophage-mediated zinc toxicity against intracellular Escherichia coli

G-protein-coupled receptor expression, function, and signaling in macrophages

Genetic control of the innate immune response

Genome-Wide Discovery of Genes Required for Capsule Production by Uropathogenic Escherichia coli

Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP.

Group A streptococcal pharyngitis: immune responses involved in bacterial clearance and GAS-associated immunopathologies

HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation.

HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi.

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages.

Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages

Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment

Histone deacetylase inhibitors in inflammatory disease.

Histone deacetylases as regulators of inflammation and immunity ⬇️

Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases

Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis

Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides

In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis.

Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a.

Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic type 2 inflammation

Inhibitors selective for HDAC6 in enzymes and cells ⬇️

Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: A ticking time bomb in ageing

Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells.

Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion

Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages

LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action

LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression

Lipopolysaccharide promotes Drp1-dependent mitochondrial fission and associated inflammatory responses in macrophages

Lysine Deacetylases and Regulated Glycolysis in Macrophages.

Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis

Macrophage secretory products induce an inflammatory phenotype in hepatocytes

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

Mechanism of Bacterial Interference with TLR4 Signaling by Brucella Toll/Interleukin-1 Receptor Domain-containing Protein TcpB

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

Minocycline Prevents the Development of Mechanical Allodynia in Mouse Models of Vincristine-Induced Peripheral Neuropathy

Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells

Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps

Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.

Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages

Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion ⬇️

Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C

Protective role for Toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E-deficient mice

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.