Lista de obras - Kristina Lorenz - Dominio Público Uruguay

"Photo-Rimonabant": Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar "<i>Cis</i>-On" CB<sub>1</sub>R Antagonist

artículo científico publicado en 2021

A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

artículo científico publicado en 2008

Age-dependent Increase in JNK2 Activity: Does This Help to Understand CaMKII-mediated Atrial Arrhythmogenesis in Human Atrial Fibrillation?

artículo científico publicado en 2018

Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation

artículo científico publicado en 2019

Analyzing ERK 1/2 signalling and targets

artículo científico publicado en 2016

Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis

artículo científico publicado en 2018

Beta-arrestin binding to the beta2-adrenergic receptor requires both receptor phosphorylation and receptor activation.

artículo científico publicado en 2005

Blocking of α4 integrin does not protect from acute ischemic stroke in mice

artículo científico publicado en 2014

CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke.

artículo científico publicado en 2014

Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.

artículo científico publicado en 2015

Cardiac amyloidosis mimicking severe aortic valve stenosis - a case report demonstrating diagnostic pitfalls and role of dobutamine stress echocardiography

artículo científico publicado en 2017

Cardiac hypertrophy: targeting Raf/MEK/ERK1/2-signaling.

artículo científico publicado en 2009

Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice

article

Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling

artículo científico publicado en 2008

Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.

artículo científico publicado en 2017

Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium

artículo científico publicado en 2014

Differences in natural history of low- and high-gradient aortic stenosis from nonsevere to severe stage of the disease.

artículo científico publicado en 2015

Ectopic expression of S28A-mutated Histone H3 modulates longevity, stress resistance and cardiac function in Drosophila.

artículo científico publicado en 2018

Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke

artículo científico publicado en 2015

Erratum: Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.

artículo científico publicado en 2016

Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC.

artículo científico publicado en 2017

FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-inflammation but not by direct neuroprotection

artículo científico publicado en 2013

Harnessing RKIP to Combat Heart Disease and Cancer

artículo científico publicado en 2022

Heart failure-specific changes in protein kinase signalling.

artículo científico publicado en 2014

How to Steer and Control ERK and the ERK Signaling Cascade Exemplified by Looking at Cardiac Insufficiency. ⬇️

artículo científico publicado en 2019

Inhibition of cardiac CaMKII to cure heart failure: step by step towards translation?

artículo científico publicado en 2016

Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects

artículo científico publicado en 2020

Loss of Survivin influences liver regeneration and is associated with impaired Aurora B function.

artículo científico publicado en 2013

Multi-OMICS: a critical technical perspective on integrative lipidomics approaches.

artículo científico publicado en 2017

Myocardial Fibrosis Predicts 10-Year Survival in Patients Undergoing Aortic Valve Replacement

artículo científico publicado en 2018

Oral Chaperone Therapy Migalastat for Treating Fabry Disease: Enzymatic Response and Serum Biomarker Changes After 1 Year

artículo científico publicado en 2019

Oxidation of cardiac myofilament proteins: Priming for dysfunction?

scientific article published on 23 August 2018

PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit.

artículo científico publicado en 2014

Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor

artículo científico publicado en 2003

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.

artículo científico publicado en 2016

Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding.

artículo científico publicado en 2016

Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2

scientific journal article

RKIP: a governor of intracellular signaling

scientific journal article

Raf kinase inhibitor protein: lessons of a better way for β-adrenergic receptor activation in the heart.

artículo científico publicado en 2017

Real-time Triggered RAdial Single-Shot Inversion recovery for arrhythmia-insensitive myocardial T1 mapping: motion phantom validation and in vivo comparison

artículo científico publicado en 2018

Sex-difference in expression and function of beta-adrenoceptors in macrovessels: role of the endothelium.

artículo científico publicado en 2017

The A2B adenosine receptor in MDA-MB-231 breast cancer cells diminishes ERK1/2 phosphorylation by activation of MAPK-phosphatase-1

artículo científico publicado en 2018

The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors

scientific article published on 08 October 2019

The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site

artículo científico publicado en 2002

The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro

artículo científico publicado en 2022

The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy

artículo científico publicado en 2005

The β2 agonist terbutaline specifically decreases pulmonary arterial pressure under normoxia and hypoxia via α adrenoceptor antagonism.

artículo científico publicado en 2018

beta-Arrestin-2 interaction and internalization of the human P2Y1 receptor are dependent on C-terminal phosphorylation sites.

artículo científico publicado en 2009

α-Galactosidase A Genotype N215S Induces a Specific Cardiac Variant of Fabry Disease

artículo científico publicado en 2017

β 1 Adrenoceptor antagonistic effects of the supposedly selective β 2 adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts.

artículo científico publicado en 2015

β-Adrenergic receptor stimulation causes cardiac hypertrophy via a Gβγ/Erk-dependent pathway

artículo científico publicado el 27 de julio de 2012

β-Adrenoceptor-Mediated Relaxation of Carbachol-Pre-Contracted Mouse Detrusor

scientific article published on 30 January 2015

β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle

artículo científico publicado en 2016

Lista de obras de Kristina Lorenz

"Photo-Rimonabant": Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar "<i>Cis</i>-On" CB<sub>1</sub>R Antagonist

A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

Age-dependent Increase in JNK2 Activity: Does This Help to Understand CaMKII-mediated Atrial Arrhythmogenesis in Human Atrial Fibrillation?

Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation

Analyzing ERK 1/2 signalling and targets

Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis

Beta-arrestin binding to the beta2-adrenergic receptor requires both receptor phosphorylation and receptor activation.

Blocking of α4 integrin does not protect from acute ischemic stroke in mice

CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke.

Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.

Cardiac amyloidosis mimicking severe aortic valve stenosis - a case report demonstrating diagnostic pitfalls and role of dobutamine stress echocardiography

Cardiac hypertrophy: targeting Raf/MEK/ERK1/2-signaling.

Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice

Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling

Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.

Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium

Differences in natural history of low- and high-gradient aortic stenosis from nonsevere to severe stage of the disease.

Ectopic expression of S28A-mutated Histone H3 modulates longevity, stress resistance and cardiac function in Drosophila.

Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke

Erratum: Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.

Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC.

FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-inflammation but not by direct neuroprotection

Harnessing RKIP to Combat Heart Disease and Cancer

Heart failure-specific changes in protein kinase signalling.

How to Steer and Control ERK and the ERK Signaling Cascade Exemplified by Looking at Cardiac Insufficiency. ⬇️

Inhibition of cardiac CaMKII to cure heart failure: step by step towards translation?

Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects

Loss of Survivin influences liver regeneration and is associated with impaired Aurora B function.

Multi-OMICS: a critical technical perspective on integrative lipidomics approaches.

Myocardial Fibrosis Predicts 10-Year Survival in Patients Undergoing Aortic Valve Replacement

Oral Chaperone Therapy Migalastat for Treating Fabry Disease: Enzymatic Response and Serum Biomarker Changes After 1 Year

Oxidation of cardiac myofilament proteins: Priming for dysfunction?

PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit.

Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.

Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding.

Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2

RKIP: a governor of intracellular signaling

Raf kinase inhibitor protein: lessons of a better way for β-adrenergic receptor activation in the heart.

Real-time Triggered RAdial Single-Shot Inversion recovery for arrhythmia-insensitive myocardial T1 mapping: motion phantom validation and in vivo comparison

Sex-difference in expression and function of beta-adrenoceptors in macrovessels: role of the endothelium.

The A2B adenosine receptor in MDA-MB-231 breast cancer cells diminishes ERK1/2 phosphorylation by activation of MAPK-phosphatase-1

The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors

The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site

The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro

The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy

The β2 agonist terbutaline specifically decreases pulmonary arterial pressure under normoxia and hypoxia via α adrenoceptor antagonism.

beta-Arrestin-2 interaction and internalization of the human P2Y1 receptor are dependent on C-terminal phosphorylation sites.

α-Galactosidase A Genotype N215S Induces a Specific Cardiac Variant of Fabry Disease

β 1 Adrenoceptor antagonistic effects of the supposedly selective β 2 adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts.

β-Adrenergic receptor stimulation causes cardiac hypertrophy via a Gβγ/Erk-dependent pathway

β-Adrenoceptor-Mediated Relaxation of Carbachol-Pre-Contracted Mouse Detrusor

β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle