Lista de obras - Alex K. Shalek - Dominio Público Uruguay

973. Single-cell RNA Sequencing Analysis of Zika Virus Infection in Human Stem Cell-Derived Cerebral Organoids

scholarly article by Karen Ocwieja et al published 23 October 2019 in Open Forum Infectious Diseases

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

article

A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

artículo científico publicado en 2018

A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood

artículo científico publicado en 2020

A case of mistaken identity

artículo científico publicado en 2017

A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages

artículo científico publicado en 2016

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

article published in 2021

A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

artículo científico publicado en 2019

Allergic inflammatory memory in human respiratory epithelial progenitor cells

artículo científico publicado en 2018

Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

artículo científico publicado en 2016

Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection

artículo científico publicado en 2019

Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods

scientific article published on 27 April 2020

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

artículo científico publicado en 2024

Baring cellular souls

artículo científico publicado en 2017

CMET-20. EVIDENCE OF CNS RESPONSE OF PEMBROLIZUMAB FOR LEPTOMENINGEAL CARCINOMATOSIS AT A SINGLE CELL RESOLUTION

Carbohydrate-Lectin Interactions Reprogram Dendritic Cells to Promote Type 1 Anti-Tumor Immunity

artículo científico publicado en 2024

Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth

artículo científico publicado en 2017

Correction to: A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

artículo científico publicado en 2020

Correction: Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

artículo científico publicado en 2017

Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells

artículo científico publicado en 2021

Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli

artículo científico publicado en 2013

Deconstructing transcriptional heterogeneity in pluripotent stem cells

artículo científico publicado en 2014

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

artículo científico publicado en 2016

Distribution and storage of inflammatory memory in barrier tissues

artículo científico publicado en 2020

Dynamic regulatory network controlling TH17 cell differentiation

artículo científico publicado en 2013

Erratum: Deconstructing transcriptional heterogeneity in pluripotent stem cells

artículo científico publicado en 2015

Evolution and Diversity of Immune Responses during Acute HIV Infection

artículo científico publicado en 2020

Functional compensation precedes recovery of tissue mass following acute liver injury

artículo científico publicado en 2020

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

artículo científico publicado en 2021

Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus

artículo científico publicado en 2019

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

artículo científico publicado en 2019

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types.

artículo científico publicado en 2018

Heterogeneity in immune responses: from populations to single cells

artículo científico publicado en 2014

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

article

High-throughput organoid screening enables engineering of intestinal epithelial composition

artículo científico publicado en 2020

Highly Efficient, Massively-Parallel Single-Cell RNA-Seq Reveals Cellular States and Molecular Features of Human Skin Pathology

artículo científico publicado en 2019

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

artículo científico publicado en 2015

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

artículo científico publicado en 2017

IL-5Rα marks nasal polyp IgG4 and IgE-expressing cells in aspirin-exacerbated respiratory disease

scientific article published on 18 March 2020

Identification of a Master Regulator of Differentiation in Toxoplasma

scientific article published on 16 January 2020

Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies

artículo científico publicado en 2020

Improved haplotype inference by exploiting long-range linking and allelic imbalance in RNA-seq datasets

scientific article published on 16 September 2020

Induction of metabolic quiescence defines the transitional to follicular B cell switch

artículo científico publicado en 2019

Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

artículo científico publicado en 2020

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

artículo científico publicado en 2017

Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy

scientific article published on 01 September 2020

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.

artículo científico publicado en 2016

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

scientific article published on 23 March 2020

Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

artículo científico publicado en 2019

LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS

artículo científico publicado en 2019

LGG-05. SINGLE-CELL RNA SEQUENCING OF PEDIATRIC LOW-GRADE GLIOMAS REVEALS INTRATUMORAL HETEROGENEITY.

artículo científico publicado en 2017

LGG-13. RESOLVING TRANSCRIPTIONAL PROFILES IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMA USING SINGLE CELL RNA SEQUENCING

artículo científico publicado en 2018

Linking single-cell measurements of mass, growth rate, and gene expression

article

Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

artículo científico publicado en 2021

Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression

artículo científico publicado en 2019

Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential

artículo científico publicado en 2020

MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data

artículo científico publicado en 2015

MERFISHing for spatial context.

artículo científico publicado en 2015

Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics

artículo científico publicado en 2015

Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

scientific article published on 30 April 2019

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

artículo científico publicado en 2019

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

artículo científico publicado en 2016

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

artículo científico publicado en 2016

Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia

artículo científico publicado en 2012

Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

artículo científico publicado en 2017

Oct1 and OCA-B are selectively required for CD4 memory T cell function

artículo científico publicado en 2015

On the right track

Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer

article published in the Proceedings of the National Academy of Sciences of the United States of America

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses

artículo científico publicado en 2015

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses

article

Photoinduced interfacial charging and "explosion" of monolayer pentacene islands

artículo científico publicado en 2005

Preparation of Single-Cell RNA-Seq Libraries for Next Generation Sequencing

artículo científico publicado en 2014

Prevention of tuberculosis in macaques after intravenous BCG immunization

scientific article published on 01 January 2020

Probing enzymatic activity inside living cells using a nanowire-cell "sandwich" assay

artículo científico publicado en 2012

Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

artículo científico publicado en 2019

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

artículo científico publicado en 2014

Reduced cellular diversity and an altered basal progenitor cell state inform epithelial barrier dysfunction in human type 2 immunity

Regulation of X-linked gene expression during early mouse development by Rlim

scientific article published on 19 September 2016

Revisiting airway epithelial remodeling in type 2 immunity: Beyond goblet cell metaplasia

artículo científico publicado en 2019

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

artículo científico publicado en 2020

SARS-CoV-2 Receptor ACE2 is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Enriched in Specific Cell Subsets Across Tissues

artículo científico publicado en 2020

Scaling by shrinking: empowering single-cell 'omics' with microfluidic devices

artículo científico publicado en 2017

Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation

artículo científico publicado en 2022

Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies

artículo científico publicado en 2020

Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses

artículo científico publicado en 2018

Seq-Well: A Sample-Efficient, Portable Picowell Platform for Massively Parallel Single-Cell RNA Sequencing

scientific article published on 01 January 2019

Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput

artículo científico publicado en 2017

Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput

Single-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn's Disease

scientific article published on 16 May 2020

Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration

scientific article published on 09 May 2019

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

artículo científico publicado en 2015

Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics

artículo científico publicado en 2020

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity

artículo científico publicado en 2019

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

artículo científico publicado en 2014

Single-cell RNA-seq reveals dynamic paracrine control of cellular variation

artículo científico publicado en 2014

Single-cell analyses to tailor treatments

artículo científico publicado en 2017

Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states

artículo científico publicado en 2022

Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration

scientific article published on 25 October 2019

Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

artículo científico publicado en 2013

Size no longer matters

artículo científico publicado en 2016

Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.

artículo científico publicado en 2014

Speed kills

Systematic comparison of single-cell and single-nucleus RNA-sequencing methods

artículo científico publicado en 2020

Systematic discovery of TLR signaling components delineates viral-sensing circuits

artículo científico publicado en 2011

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

artículo científico publicado en 2018

TCR sequencing paired with massively parallel 3' RNA-seq reveals clonotypic T cell signatures

scientific article published on 19 November 2019

The Human Cell Atlas

artículo científico publicado en 2017

The Human Cell Atlas

The Human Cell Atlas White Paper ⬇️

artículo científico publicado en 2018

The Human Cell Atlas and equity: lessons learned

artículo científico publicado en 2020

The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

scientific article published on 01 April 2020

The cellular architecture of the antimicrobial response network in human leprosy granulomas

artículo científico publicado en 2021

Transcriptional and epigenetic dynamics during specification of human embryonic stem cells

artículo científico publicado en 2013

Vertical nanowire electrode arrays as a scalable platform for intracellular interfacing to neuronal circuits.

artículo científico publicado en 2012

Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells.

artículo científico publicado en 2010

Voices in methods development

artículo científico publicado en 2019

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

artículo científico publicado en 2014

Lista de obras de Alex K. Shalek

973. Single-cell RNA Sequencing Analysis of Zika Virus Infection in Human Stem Cell-Derived Cerebral Organoids

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood

A case of mistaken identity

A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

Allergic inflammatory memory in human respiratory epithelial progenitor cells

Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection

Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

Baring cellular souls

CMET-20. EVIDENCE OF CNS RESPONSE OF PEMBROLIZUMAB FOR LEPTOMENINGEAL CARCINOMATOSIS AT A SINGLE CELL RESOLUTION

Carbohydrate-Lectin Interactions Reprogram Dendritic Cells to Promote Type 1 Anti-Tumor Immunity

Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth

Correction to: A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

Correction: Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells

Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli

Deconstructing transcriptional heterogeneity in pluripotent stem cells

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Distribution and storage of inflammatory memory in barrier tissues

Dynamic regulatory network controlling TH17 cell differentiation

Erratum: Deconstructing transcriptional heterogeneity in pluripotent stem cells

Evolution and Diversity of Immune Responses during Acute HIV Infection

Functional compensation precedes recovery of tissue mass following acute liver injury

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types.

Heterogeneity in immune responses: from populations to single cells

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

High-throughput organoid screening enables engineering of intestinal epithelial composition

Highly Efficient, Massively-Parallel Single-Cell RNA-Seq Reveals Cellular States and Molecular Features of Human Skin Pathology

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

IL-5Rα marks nasal polyp IgG4 and IgE-expressing cells in aspirin-exacerbated respiratory disease

Identification of a Master Regulator of Differentiation in Toxoplasma

Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies

Improved haplotype inference by exploiting long-range linking and allelic imbalance in RNA-seq datasets

Induction of metabolic quiescence defines the transitional to follicular B cell switch

Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS

LGG-05. SINGLE-CELL RNA SEQUENCING OF PEDIATRIC LOW-GRADE GLIOMAS REVEALS INTRATUMORAL HETEROGENEITY.

LGG-13. RESOLVING TRANSCRIPTIONAL PROFILES IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMA USING SINGLE CELL RNA SEQUENCING

Linking single-cell measurements of mass, growth rate, and gene expression

Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression

Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential

MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data

MERFISHing for spatial context.

Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics

Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia

Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

Oct1 and OCA-B are selectively required for CD4 memory T cell function

On the right track

Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses

Photoinduced interfacial charging and "explosion" of monolayer pentacene islands

Preparation of Single-Cell RNA-Seq Libraries for Next Generation Sequencing

Prevention of tuberculosis in macaques after intravenous BCG immunization

Probing enzymatic activity inside living cells using a nanowire-cell "sandwich" assay

Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

Reduced cellular diversity and an altered basal progenitor cell state inform epithelial barrier dysfunction in human type 2 immunity

Regulation of X-linked gene expression during early mouse development by Rlim

Revisiting airway epithelial remodeling in type 2 immunity: Beyond goblet cell metaplasia