Lista de obras - Lucio Merlini - Dominio Público Uruguay

(+)-Abscisic acid, a metabolite of the fungusCercospora rosicola

artículo científico publicado en 2005

7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors

artículo científico publicado en 2013

A New Azoxyalkene from a Strain of anActinomadura-Like Fungus

artículo científico publicado en 2003

A Synthetic Approach to Sporotricale Methylether

A new 3,4-seco-lupane derivative from Lasianthus gardneri

artículo científico publicado en 2004

A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.

artículo científico publicado en 2010

A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin

artículo científico publicado en 2005

A new synthesis of the cytotoxic alkaloid Luotonine A

A novel atypical retinoid endowed with proapoptotic and antitumor activity

artículo científico publicado en 2003

Alkaloids of Uncaria elliptica

artículo científico publicado en 2003

An unusual dimer of camptothecin-7-aldehyde

Antimicrobial activity of some Sri Lankan Rubiaceae and Meliaceae

artículo científico publicado en 2002

Antitumor Activity of the Retinoid-Related Molecules (E)-3-(4'-Hydroxy-3'-adamantylbiphenyl-4-yl)acrylic Acid (ST1926) and 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid (CD437) in F9 Teratocarcinoma: Role of Retinoic Acid Receptor

artículo científico publicado en 2006

Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity

artículo científico publicado en 2008

Camptothecin and Analogs: Structure and Synthetic Efforts

Constituents of Dragon's Blood. 5. Dracoflavans B1, B2, C1, C2, D1, and D2, new A-type deoxyproanthocyanidins

artículo científico publicado en 1997

Corrigendum to “Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors” [Bioorg. Med. Chem. 18 (2010) 6031–6043]

scholarly article published in Bioorganic & Medicinal Chemistry

Current status and perspectives in the development of camptothecins

artículo científico publicado en 2002

Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors

artículo científico publicado en 2008

Enantioselective total synthesis and absolute configuration of the alleged structure of crassinervic acid

Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system

artículo científico publicado en 2010

First total synthesis of topopyrone C

Flavonoids from Adenanthera pavonina

article published in 2002

General pseudoreceptor model for sweet compounds: a semiquantitative prediction of binding affinity for sweet-tasting molecules

artículo científico publicado en 2002

Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties

artículo científico publicado en 2012

Intramolecular Friedel-Crafts Reaction of Indoles with Carbonyl Groups: A Simple Synthesis of 3- and 4-Substituted β-Carbolin-1-ones

Intramolecular N-acyliminium ion versus Friedel–Crafts cyclization onto 3-indoles: synthesis of the novel rings pyrrolizino[2,1-b]indole and homologues

Isoflavonoid constituents of the west african red wood Baphia nitida

artículo científico publicado en 2002

Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors

artículo científico publicado en 2012

Metabolites of Cercospora. Taiwapyrone, an α-pyrone of unusual structure from Cercospora taiwanensis

artículo científico publicado en 2002

Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors

artículo científico publicado en 2010

New chromenochalcones from Flemingia

New retinoid derivatives as back-ups of Adarotene

artículo científico publicado en 2012

Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity

artículo científico publicado en 2001

Novel 7-substituted camptothecins with potent antitumor activity

artículo científico publicado en 2000

Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin.

artículo científico publicado en 2001

Optimized synthesis and enhanced efficacy of novel triplex-forming camptothecin derivatives based on gimatecan

artículo científico publicado en 2009

Perspectives in camptothecin development

article

Perylenequinones from cucumber seedlings infected with Cladosporium cucumerinum

artículo científico publicado en 2002

Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series

artículo científico publicado en 2006

Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.

artículo científico publicado en 2008

Progress in isovanillyl sweet compounds

Secondary metabolites from Mycosphaerella ligulicola

artículo científico publicado en 2002

Short Synthesis of Cytotoxic 4‐Arylcoumarins

Structure elucidation of clavilactone D: an inhibitor of protein tyrosine kinases

artículo científico publicado en 2000

Synthesis and Antifungal Activity of 2-Hydroxy-4,5-methylenedioxyaryl Ketones as Analogues of Kakuol

scientific article published on 01 April 2010

Synthesis and anti-fungal activity of simple β-lactams

Synthesis and antifungal activity of a series of N-substituted [2-(2,4-dichlorophenyl)-3-(1,2,4-triazol-1-yl)]propylamines

artículo científico publicado en 2007

Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors

artículo científico publicado en 2007

Synthesis and cytotoxic activity of new 9-substituted camptothecins

artículo científico publicado en 2008

Synthesis and cytotoxic activity of polyamine analogues of camptothecin

artículo científico publicado en 2006

Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin

artículo científico publicado en 2004

Synthesis and cytotoxic activity of substituted luotonin A derivatives

artículo científico publicado en 2004

Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity

artículo científico publicado en 2005

Synthesis and structure-activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids

artículo científico publicado en 2007

Synthesis and topoisomerase I inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D.

artículo científico publicado en 2011

Synthesis of (+)-Spirolaxine Methyl Ether

scientific article published on 01 August 2006

Synthesis of new cytotoxic E-ring modified camptothecins

Synthesis of photoactivable inhibitors of osteoclast vacuolar ATPase

artículo científico publicado en 2003

Synthesis, fungicidal activity, and QSAR of a series of 2-dichlorophenyl-3-triazolylpropyl ethers

artículo científico publicado en 2000

Synthesis, modeling, and RET protein kinase inhibitory activity of 3- and 4-substituted beta-carbolin-1-ones

artículo científico publicado en 2008

The structure of cercosporin, a naturally occurring quinone

artículo científico publicado en 2004

The structure of roxburghines A-E, new indole alkaloids from an Uncaria Sp

scientific article published on 01 May 1970

Total Synthesis of Berkeleyamide A and its 10-epi Isomer

Total synthesis of the natural product benzo[j]fluoranthene-4,9-diol: an approach to the synthesis of oxygenated benzo[j]fluoranthenes

artículo científico publicado en 2013

Trends in searching for new cognition enhancing drugs

artículo científico publicado en 1989

Lista de obras de Lucio Merlini

(+)-Abscisic acid, a metabolite of the fungusCercospora rosicola

7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors

A New Azoxyalkene from a Strain of anActinomadura-Like Fungus

A Synthetic Approach to Sporotricale Methylether

A new 3,4-seco-lupane derivative from Lasianthus gardneri

A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.

A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin

A new synthesis of the cytotoxic alkaloid Luotonine A

A novel atypical retinoid endowed with proapoptotic and antitumor activity

Alkaloids of Uncaria elliptica

An unusual dimer of camptothecin-7-aldehyde

Antimicrobial activity of some Sri Lankan Rubiaceae and Meliaceae

Antitumor Activity of the Retinoid-Related Molecules (E)-3-(4'-Hydroxy-3'-adamantylbiphenyl-4-yl)acrylic Acid (ST1926) and 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid (CD437) in F9 Teratocarcinoma: Role of Retinoic Acid Receptor

Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity

Camptothecin and Analogs: Structure and Synthetic Efforts

Constituents of Dragon's Blood. 5. Dracoflavans B1, B2, C1, C2, D1, and D2, new A-type deoxyproanthocyanidins

Corrigendum to “Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors” [Bioorg. Med. Chem. 18 (2010) 6031–6043]

Current status and perspectives in the development of camptothecins

Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors

Enantioselective total synthesis and absolute configuration of the alleged structure of crassinervic acid

Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system

First total synthesis of topopyrone C

Flavonoids from Adenanthera pavonina

General pseudoreceptor model for sweet compounds: a semiquantitative prediction of binding affinity for sweet-tasting molecules

Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties

Intramolecular Friedel-Crafts Reaction of Indoles with Carbonyl Groups: A Simple Synthesis of 3- and 4-Substituted β-Carbolin-1-ones

Intramolecular N-acyliminium ion versus Friedel–Crafts cyclization onto 3-indoles: synthesis of the novel rings pyrrolizino[2,1-b]indole and homologues

Isoflavonoid constituents of the west african red wood Baphia nitida

Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors

Metabolites of Cercospora. Taiwapyrone, an α-pyrone of unusual structure from Cercospora taiwanensis

Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors

New chromenochalcones from Flemingia

New retinoid derivatives as back-ups of Adarotene

Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity

Novel 7-substituted camptothecins with potent antitumor activity

Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin.

Optimized synthesis and enhanced efficacy of novel triplex-forming camptothecin derivatives based on gimatecan

Perspectives in camptothecin development

Perylenequinones from cucumber seedlings infected with Cladosporium cucumerinum

Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series

Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.

Progress in isovanillyl sweet compounds

Secondary metabolites from Mycosphaerella ligulicola

Short Synthesis of Cytotoxic 4‐Arylcoumarins

Structure elucidation of clavilactone D: an inhibitor of protein tyrosine kinases

Synthesis and Antifungal Activity of 2-Hydroxy-4,5-methylenedioxyaryl Ketones as Analogues of Kakuol

Synthesis and anti-fungal activity of simple β-lactams

Synthesis and antifungal activity of a series of N-substituted [2-(2,4-dichlorophenyl)-3-(1,2,4-triazol-1-yl)]propylamines

Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors

Synthesis and cytotoxic activity of new 9-substituted camptothecins

Synthesis and cytotoxic activity of polyamine analogues of camptothecin

Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin

Synthesis and cytotoxic activity of substituted luotonin A derivatives

Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity

Synthesis and structure-activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids

Synthesis and topoisomerase I inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D.

Synthesis of (+)-Spirolaxine Methyl Ether

Synthesis of new cytotoxic E-ring modified camptothecins

Synthesis of photoactivable inhibitors of osteoclast vacuolar ATPase

Synthesis, fungicidal activity, and QSAR of a series of 2-dichlorophenyl-3-triazolylpropyl ethers

Synthesis, modeling, and RET protein kinase inhibitory activity of 3- and 4-substituted beta-carbolin-1-ones

The structure of cercosporin, a naturally occurring quinone

The structure of roxburghines A-E, new indole alkaloids from an Uncaria Sp

Total Synthesis of Berkeleyamide A and its 10-epi Isomer

Total synthesis of the natural product benzo[j]fluoranthene-4,9-diol: an approach to the synthesis of oxygenated benzo[j]fluoranthenes

Trends in searching for new cognition enhancing drugs