Lista de obras - Wynand P Roos - Dominio Público Uruguay

Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

artículo científico publicado en 2006

Apoptosis induced by MNNG in human TK6 lymphoblastoid cells is p53 and Fas/CD95/Apo-1 related

artículo científico publicado en 2003

Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.

artículo científico publicado en 2004

Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling

artículo científico publicado en 2008

Artesunate derived from traditional Chinese medicine induces DNA damage and repair.

artículo científico publicado en 2008

Assessing the Effect of Class I Histone Deacetylase Activity on DNA Double-Strand Break Repair by Homologous Recombination

artículo científico publicado en 2017

B-Raf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells.

artículo científico publicado en 2014

Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs

artículo científico publicado en 2008

Chloroethylating nitrosoureas in cancer therapy: DNA damage, repair and cell death signaling.

artículo científico publicado en 2017

Cisplatin sensitivity is related to late DNA damage processing and checkpoint control rather than to the early DNA damage response.

artículo científico publicado en 2009

Contribution of ATM and ATR to the Resistance of Glioblastoma and Malignant Melanoma Cells to the Methylating Anticancer Drug Temozolomide ⬇️

artículo científico publicado el 19 de agosto de 2013

Cytolethal distending toxin (CDT) is a radiomimetic agent and induces persistent levels of DNA double-strand breaks in human fibroblasts

artículo científico publicado en 2014

DNA damage and the balance between survival and death in cancer biology

artículo científico publicado en 2016

DNA damage-induced cell death by apoptosis.

artículo científico publicado en 2006

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis ⬇️

artículo científico publicado el 17 de enero de 2012

DNA replication arrest in response to genotoxic stress provokes early activation of stress-activated protein kinases (SAPK/JNK).

artículo científico publicado en 2008

Determination of the initial DNA damage and residual DNA damage remaining after 12 hours of repair in eleven cell lines at low doses of irradiation

artículo científico publicado en 2000

Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks.

artículo científico publicado en 2007

Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance.

artículo científico publicado en 2016

In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi) ⬇️

artículo científico publicado en 2020

Intrinsic anticancer drug resistance of malignant melanoma cells is abrogated by IFN-β and valproic acid.

artículo científico publicado en 2011

Lovastatin protects human endothelial cells from killing by ionizing radiation without impairing induction and repair of DNA double-strand breaks

artículo científico publicado en 2006

Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/XPC-mediated DNA repair ⬇️

artículo científico publicado el 22 de abril de 2013

Mechanisms of human DNA repair: an update

scientific journal article

Micronucleus response of human glioblastoma and neuroblastoma cells toward low-LET photon and high-LET p(66)/Be neutron irradiation

artículo científico publicado en 2003

Mouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O(6)-methylguanine due to high E2F1 regulated mismatch repair

artículo científico publicado en 2007

Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.

artículo científico publicado en 2010

O6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistry ⬇️

artículo científico publicado el 1 de julio de 2011

O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells

artículo científico publicado en 2006

Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles

artículo científico publicado en 2010

Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons.

artículo científico publicado en 2012

Rad51 and BRCA2--New molecular targets for sensitizing glioma cells to alkylating anticancer drugs

artículo científico publicado en 2011

Response of pancreatic cancer cells treated with interferon-alpha or beta and co-exposed to ionising radiation.

artículo científico publicado en 2010

Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage

artículo científico publicado en 2013

Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy

artículo científico publicado en 2014

Temozolomide induces senescence and repression of DNA repair pathways in glioblastoma cells via activation of ATR-CHK1, p21, and NF-kB

artículo científico publicado en 2018

Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.

artículo científico publicado en 2009

The SIAH1-HIPK2-p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death

scientific article published on 22 February 2019

The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers.

artículo científico

The influence of chromatin structure on initial DNA damage and radiosensitivity in CHO-K1 and xrs1 cells at low doses of irradiation 1-10 Gy.

artículo científico publicado en 2002

The multifaceted influence of histone deacetylases on DNA damage signalling and DNA repair

artículo científico publicado en 2016

The translesion polymerase Rev3L in the tolerance of alkylating anticancer drugs.

artículo científico publicado en 2009

WRN protects against topo I but not topo II inhibitors by preventing DNA break formation

artículo científico publicado en 2008

XRCC3 contributes to temozolomide resistance of glioblastoma cells by promoting DNA double-strand break repair

artículo científico publicado en 2018

p53 mutant human glioma cells are sensitive to UV-C-induced apoptosis due to impaired cyclobutane pyrimidine dimer removal.

artículo científico publicado en 2009

Lista de obras de Wynand P Roos

Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

Apoptosis induced by MNNG in human TK6 lymphoblastoid cells is p53 and Fas/CD95/Apo-1 related

Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.

Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling

Artesunate derived from traditional Chinese medicine induces DNA damage and repair.

Assessing the Effect of Class I Histone Deacetylase Activity on DNA Double-Strand Break Repair by Homologous Recombination

B-Raf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells.

Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs

Chloroethylating nitrosoureas in cancer therapy: DNA damage, repair and cell death signaling.

Cisplatin sensitivity is related to late DNA damage processing and checkpoint control rather than to the early DNA damage response.

Contribution of ATM and ATR to the Resistance of Glioblastoma and Malignant Melanoma Cells to the Methylating Anticancer Drug Temozolomide ⬇️

Cytolethal distending toxin (CDT) is a radiomimetic agent and induces persistent levels of DNA double-strand breaks in human fibroblasts

DNA damage and the balance between survival and death in cancer biology

DNA damage-induced cell death by apoptosis.

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis ⬇️

DNA replication arrest in response to genotoxic stress provokes early activation of stress-activated protein kinases (SAPK/JNK).

Determination of the initial DNA damage and residual DNA damage remaining after 12 hours of repair in eleven cell lines at low doses of irradiation

Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks.

Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance.

In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi) ⬇️

Intrinsic anticancer drug resistance of malignant melanoma cells is abrogated by IFN-β and valproic acid.

Lovastatin protects human endothelial cells from killing by ionizing radiation without impairing induction and repair of DNA double-strand breaks

Malignant melanoma cells acquire resistance to DNA interstrand cross-linking chemotherapeutics by p53-triggered upregulation of DDB2/XPC-mediated DNA repair ⬇️

Mechanisms of human DNA repair: an update

Micronucleus response of human glioblastoma and neuroblastoma cells toward low-LET photon and high-LET p(66)/Be neutron irradiation

Mouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O(6)-methylguanine due to high E2F1 regulated mismatch repair

Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.

O6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistry ⬇️

O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells

Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles

Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons.

Rad51 and BRCA2--New molecular targets for sensitizing glioma cells to alkylating anticancer drugs

Response of pancreatic cancer cells treated with interferon-alpha or beta and co-exposed to ionising radiation.

Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage

Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy

Temozolomide induces senescence and repression of DNA repair pathways in glioblastoma cells via activation of ATR-CHK1, p21, and NF-kB

Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.

The SIAH1-HIPK2-p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death

The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers.

The influence of chromatin structure on initial DNA damage and radiosensitivity in CHO-K1 and xrs1 cells at low doses of irradiation 1-10 Gy.

The multifaceted influence of histone deacetylases on DNA damage signalling and DNA repair

The translesion polymerase Rev3L in the tolerance of alkylating anticancer drugs.

WRN protects against topo I but not topo II inhibitors by preventing DNA break formation

XRCC3 contributes to temozolomide resistance of glioblastoma cells by promoting DNA double-strand break repair

p53 mutant human glioma cells are sensitive to UV-C-induced apoptosis due to impaired cyclobutane pyrimidine dimer removal.