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Lista de obras de José V Castell

A Comprehensive Untargeted Metabonomic Analysis of Human Steatotic Liver Tissue by RP and HILIC Chromatography Coupled to Mass Spectrometry Reveals Important Metabolic Alterations

article

A Microassay for Measuring Cytochrome P450IA1 and Cytochrome P450IIB1 Activities in Intact Human and Rat Hepatocytes Cultured on 96-Well Plates

artículo científico publicado en 1993

A Network Involving Gut Microbiota, Circulating Bile Acids, and Hepatic Metabolism Genes That Protects Against Non-Alcoholic Fatty Liver Disease

scientific article published on 30 July 2019

A Novel MicroRNA Signature for Cholestatic Drugs in Human Hepatocytes and Its Translation into Novel Circulating Biomarkers for Drug-Induced Liver Injury Patients

scientific article published on 01 February 2020

A Physiology-Based Model of Human Bile Acid Metabolism for Predicting Bile Acid Tissue Levels After Drug Administration in Healthy Subjects and BRIC Type 2 Patients

scientific article published on 27 September 2019

A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR).

artículo científico publicado en 2013

A convenient micromethod for the assay of primary amines and proteins with fluorescamine. A reexamination of the conditions of reaction ⬇️

artículo científico publicado el 1 de noviembre de 1979

A human hepatocellular in vitro model to investigate steatosis.

artículo científico publicado en 2006

A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury.

artículo científico publicado en 2016

A microassay for measuring glycogen in 96-well-cultured cells.

artículo científico publicado en 1996

A newin vitroapproach for the simultaneous determination of phase I and phase II enzymatic activities of human hepatocyte preparations

artículo científico publicado en 2008

A score model for the continuous grading of early allograft dysfunction severity.

artículo científico publicado en 2014

A simple transcriptomic signature able to predict drug-induced hepatic steatosis.

artículo científico publicado en 2014

A specific microassay for evaluating hepatic LDH activity in co-cultures of hepatocytes with other cells

article

ATF5 is a highly abundant liver-enriched transcription factor that cooperates with constitutive androstane receptor in the transactivation of CYP2B6: implications in hepatic stress responses.

artículo científico publicado en 2008

Acute-phase response of human hepatocytes: Regulation of acute-phase protein synthesis by interleukin-6

article

Adenovirus-mediated gene transfer into human hepatocytes: analysis of the biochemical functionality of transduced cells.

artículo científico publicado en 1997

Advances in drug-induced cholestasis: Clinical perspectives, potential mechanisms and in vitro systems

artículo científico publicado en 2018

An In Vitro Approach to Drug Photoallergy: Use of Drug-directed Antibodies to Assess Photobinding of Non-steroidal Anti-inflammatories to Skin Cells

artículo científico publicado en 1999

An enzyme immunoassay for the quantitation of rat liver carbamoyl-phosphate synthetase I.

artículo científico publicado en 1988

An update on metabolism studies using human hepatocytes in primary culture

article

Angiopoietin-Like Protein 8 Is a Novel Vitamin D Receptor Target Gene Involved in Non-Alcoholic Fatty Liver Pathogenesis

article

Antibodies directed to drug epitopes to investigate the structure of drug-protein photoadducts. Recognition of a common photobound substructure in tiaprofenic acid/ketoprofen cross-photoreactivity.

artículo científico publicado en 2001

Assessment of cytochrome P450 induction in human hepatocytes using the cocktail strategy plus liquid chromatography tandem mass spectrometry.

artículo científico publicado en 2008

Biotransformation in vitro of the 22R and 22S epimers of budesonide by human liver, bronchus, colonic mucosa and skin.

artículo científico publicado en 2001

Bladder cancer recurrence surveillance by urine metabolomics analysis.

artículo científico publicado en 2018

Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development.

artículo científico publicado en 2016

CCAAT/enhancer-binding protein alpha (C/EBPalpha) and hepatocyte nuclear factor 4alpha (HNF4alpha) synergistically cooperate with constitutive androstane receptor to transactivate the human cytochrome P450 2B6 (CYP2B6) gene: application to the devel

artículo científico publicado en 2010

Characterization of drug metabolizing activities in pig hepatocytes for use in bioartificial liver devices: comparison with other hepatic cellular models

article

Chemometric approaches to improve PLSDA model outcome for predicting human non-alcoholic fatty liver disease using UPLC-MS as a metabolic profiling tool

article

Clinical Outcome of Hepatocyte Transplantation in Four Pediatric Patients with Inherited Metabolic Diseases

article

Co-cultures of hepatocytes with epithelial-like cell lines: expression of drug-biotransformation activities by hepatocytes

artículo científico publicado en 1991

Cocaine hepatotoxicity: two different toxicity mechanisms for phenobarbital-induced and non-induced rat hepatocytes.

artículo científico publicado en 1993

Comparative Metabolism of Thiabendazole in Cultured Hepatocytes from Rats, Rabbits, Calves, Pigs, and Sheep, Including the Formation of Protein-Bound Residues

scientific article published on 01 February 1998

Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems

artículo científico publicado en 2003

Comparing Targeted vs. Untargeted MS2 Data-Dependent Acquisition for Peak Annotation in LC-MS Metabolomics

artículo científico publicado en 2020

Constitutive and inducible expression of CYP enzymes in immortal hepatocytes derived from SV40 transgenic mice

artículo científico publicado en 2003

Contribution to the Understanding of Particle Motion Perception in Marine Invertebrates.

artículo científico publicado en 2016

Coordinated induction of drug transporters and phase I and II metabolism in human liver slices.

artículo científico publicado en 2008

Cytochrome P-450 mRNA Expression in Human Liver and Its Relationship with Enzyme Activity

article

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

artículo científico publicado en 2002

Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus-mediated antisense targeting.

artículo científico

Cytometric analysis for drug-induced steatosis in HepG2 cells.

artículo científico publicado en 2009

Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry

artículo científico publicado en 2007

Development of an expert system rulebase for the prospective identification of photoallergens.

artículo científico publicado en 2000

Diagnosis of malignant ascites

artículo científico publicado en 1988

Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: a quantitative method for oxidative stress assessment of nanoparticle-treated cells.

artículo científico publicado en 2013

Diclofenac induces apoptosis in hepatocytes

artículo científico publicado en 2003

Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

artículo científico publicado en 2003

Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector

artículo científico publicado en 2019

Drug-Photosensitized Protein Modification: Identification of the Reactive Sites and Elucidation of the Reaction Mechanisms with Tiaprofenic Acid/Albumin as Model System†

article

EU research activities in alternative testing strategies: current status and future perspectives

scientific article published on 01 December 2009

Effect of Glucocorticoids on the Expression of γ-Glutamyltransferase and Tyrosine Aminotransferase in Serum-Free-Cultured Hepatocytes ⬇️

artículo científico publicado el 1 de mayo de 1983

Effect of xenobiotics on monooxygenase activities in cultured human hepatocytes

artículo científico publicado en 1990

Effects of steatosis on drug-metabolizing capability of primary human hepatocytes

scientific article published on 28 July 2006

Enantioselective Discrimination in the Intramolecular Quenching of an Excited Aromatic Ketone by a Ground-State Phenol

scientific article published in 1999

Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile.

artículo científico publicado en 2010

Enzyme-linked immunosorbent assay to quantify fibronectin.

artículo científico publicado en 1985

Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes

artículo científico publicado en 2020

Establishment and characterization of immortal hepatocytes derived from various transgenic mouse lines.

artículo científico publicado en 2002

Evaluation of Cytochrome P450 Activities in Human Hepatocytes In Vitro

scientific article published on 01 January 2012

Evaluation of drug-metabolizing and functional competence of human hepatocytes incubated under hypothermia in different media for clinical infusion

artículo científico publicado en 2008

Evaluation of ketoprofen (R,S and R/S) phototoxicity by a battery of in vitro assays

artículo científico publicado en 1995

Evaluation of the cytotoxicity of ten chemicals on human cultured hepatocytes: Predictability of human toxicity and comparison with rodent cell culture systems ⬇️

artículo científico publicado el 1 de enero de 1992

Evidence of antibodies to erythromycin in serum of a patient following an episode of acute drug-induced hepatitis

artículo científico publicado en 1996

Exploring Mass Spectrometry Suitability to Examine Human Liver Graft Metabonomic Profiles

scientific article published on 01 October 2010

Extending metabolome coverage for untargeted metabolite profiling of adherent cultured hepatic cells

artículo científico publicado en 2016

Fate and biological action of human recombinant interleukin 1β in the ratin vivo

artículo científico publicado en 1989

Fate of interleukin-6 in the rat. Involvement of skin in its catabolism

scientific article published on 01 April 1990

Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes

artículo científico publicado en 2004

Fluorescent benzofurazan-cholic acid conjugates for in vitro assessment of bile acid uptake and its modulation by drugs

artículo científico publicado en 2009

Fluorometric Microassay to Quantify Microsomal Epoxide Hydrolase in 96-Well Plates

scientific article published on 01 September 1995

Fluorometric assays in the study of nucleic acid-protein interactions

artículo científico publicado en 1978

Fluorometric assays in the study of nucleic acid-protein interactions

artículo científico publicado en 1978

Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver

artículo científico publicado en 2012

Fuentes alternativas de hepatocitos para la terapia celular

artículo científico publicado en 2006

Functional characterization of hepatocytes for cell transplantation: customized cell preparation for each receptor.

artículo científico publicado en 2010

Functionality of cultured human hepatocytes from elective samples, cadaveric grafts and hepatectomies.

artículo científico publicado en 2003

Gata4 blocks somatic cell reprogramming by directly repressing Nanog.

artículo científico publicado en 2013

Glutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells

scientific article published on 29 November 2019

Growth-promoting and tumourigenic activity of c-Myc is suppressed by Hhex

artículo científico publicado en 2014

HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.

artículo científico publicado en 2013

Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent

scientific article published on 01 July 2000

Hepatic toxicity of paraquat in primary cultures of rat hepatocytes

article

Hepatocyte transplantation program: Lessons learned and future strategies

artículo científico publicado en 2016

Hepatocyte transplantation, a step forward?

scientific article published on 17 April 2019

Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.

artículo científico publicado en 2006

High Expression of Human CYP2C in Immortalized Human Liver Epithelial Cells

artículo científico publicado en 1999

High-content screening of drug-induced mitochondrial impairment in hepatic cells: effects of statins

scientific article published on 27 August 2014

Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.

artículo científico publicado en 2016

Human hepatocyte transplantation in patients with hepatic failure awaiting a graft

artículo científico publicado en 2013

Human hepatocytes as a tool for studying toxicity and drug metabolism.

artículo científico publicado en 2003

Human mesenchymal stem cells from adipose tissue: Differentiation into hepatic lineage

artículo científico publicado en 2006

Human neonatal hepatocyte transplantation induces long-term rescue of unconjugated hyperbilirubinemia in the Gunn rat.

artículo científico publicado en 2015

INVOLVEMENT OF DRUG-DERIVED PEROXIDES IN THE PHOTOTOXICITY OF NAPROXEN and TIAPROFENIC ACID

scientific article published on 01 March 1993

Immunochemical detection of protein adducts in cultured human hepatocytes exposed to diclofenac

scientific article published on 01 December 1995

Improving the Techniques for Human Hepatocyte Transplantation: Report from a Consensus Meeting in London

scholarly article by Juliana Puppi et al published January 2012 in Cell Transplantation

Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London.

artículo científico publicado en 2012

In vitro ADME medium/high-throughput screening in drug preclinical development.

artículo científico publicado en 2006

In vitro assessment of the phototoxicity of anti-inflammatory 2-arylpropionic acids

artículo científico publicado en 1991

In vitro photoperoxidation as an indicator of the potential phototoxicity of non-steroidal anti-inflammatory 2-arylpropionic acids

scientific article published on 01 July 1993

In vitro studies on DNA-photosensitization by different drug stereoisomers.

artículo científico publicado en 2003

Increased toxicity of cocaine on human hepatocytes induced by ethanol: role of GSH.

artículo científico publicado en 1999

Induction of hepatic heme oxygenase-1 by diclofenac in rodents: role of oxidative stress and cytochrome P-450 activity.

artículo científico publicado en 2003

Influence of platelet lysate on the recovery and metabolic performance of cryopreserved human hepatocytes upon thawing

artículo científico publicado en 2011

Influence of preservation solution on the isolation and culture of human hepatocytes from liver grafts.

artículo científico publicado en 2005

Inhibition of human P450 enzymes by natural extracts used in traditional medicine.

artículo científico publicado en 2009

Inhibition of monooxygenase activities in human hepatocytes by interferons

artículo científico publicado en 1993

Interaction between Hhex and SOX13 modulates Wnt/TCF activity

artículo científico publicado en 2009

Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices.

artículo científico publicado en 2014

Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes

artículo científico publicado en 1989

Intracellular glutathione in human hepatocytes incubated with S-adenosyl-L-methionine and GSH-depleting drugs

artículo científico publicado en 1991

LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells.

artículo científico publicado en 2015

Liver cell culture techniques.

artículo científico publicado en 2009

Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes

scientific article published on 13 November 2018

Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix

artículo científico publicado en 1998

Long-term storage of peroxidase-labelled immunoglobulins for use in enzyme immunoassay

artículo científico publicado en 1987

MOLECULAR BASIS OF DRUG PHOTOTOXICITY: PHOTOSENSITIZED CELL DAMAGE BY THE MAJOR PHOTOPRODUCT OF TIAPROFENIC ACID

artículo científico publicado en 1994

Mangifera indica L. extract and mangiferin modulate cytochrome P450 and UDP-glucuronosyltransferase enzymes in primary cultures of human hepatocytes.

artículo científico publicado en 2012

Mechanism-based selection of compounds for the development of innovative in vitro approaches to hepatotoxicity studies in the LIINTOP project.

scientific article published on 23 July 2010

Mechanisms of drug photobinding to proteins: photobinding of suprofen to human serum albumin.

artículo científico publicado en 2001

Mechanisms of photosensitization by drugs: Involvement of tyrosines in the photomodification of proteins mediated by tiaprofenic acid in vitro

artículo científico publicado en 1997

Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach.

artículo científico publicado en 2005

Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients.

artículo científico publicado en 2016

Modulation of P450 enzymes by Cuban natural products rich in polyphenolic compounds in rat hepatocytes.

artículo científico publicado en 2007

Molecular mechanism of diclofenac hepatotoxicity: Association of cell injury with oxidative metabolism and decrease in ATP levels

artículo científico publicado en 1995

Monitoring of system conditioning after blank injections in untargeted UPLC-MS metabolomic analysis

artículo científico publicado en 2019

Multiparametric characterization by flow cytometry of flow-sorted subpopulations of a human hepatoma cell line useful for drug research.

artículo científico publicado en 2005

Multiparametric evaluation of the cytoprotective effect of the Mangifera indica L. stem bark extract and mangiferin in HepG2 cells

artículo científico publicado en 2013

Neonatal livers: a source for the isolation of good-performing hepatocytes for cell transplantation

artículo científico publicado en 2013

New non-woven polyurethane-based biomaterials for the cultivation of hepatocytes: expression of differentiated functions

artículo científico publicado en 2000

Non-invasive prediction of NAFLD severity: a comprehensive, independent validation of previously postulated serum microRNA biomarkers

artículo científico publicado en 2018

O - and N -glycosylation lead to different molecular mass forms of human monocyte interleukin-6

artículo científico publicado en 1989

Over-expression of neuropathy target esterase activity in bovine chromaffin cell cultures by adenovirus-mediated gene transfer.

artículo científico publicado en 2006

Overexpression of SND p102, a rat homologue of p100 coactivator, promotes the secretion of lipoprotein phospholipids in primary hepatocytes

artículo científico publicado en 2006

PHOTODYNAMIC LIPID PEROXIDATION BY THE PHOTOSENSITIZING NONSTEROIDAL ANTIINFLAMMATORY DRUGS SUPROFEN AND TIAPROFENIC ACID

artículo científico publicado en 1994

PHOTOLYTIC DEGRADATION OF IBUPROFEN. TOXICITY OF THE ISOLATED PHOTOPRODUCTS ON FIBROBLASTS and ERYTHROCYTES

article

Photobinding of drugs to cells as an indicator of potential photoallergy

artículo científico publicado en 1995

Photolytic degradation of benorylate: effects of the photoproducts on cultured hepatocytes

artículo científico publicado en 1987

Photophysical characterization and flow cytometry applications of cholylamidofluorescein, a fluorescent bile acid scaffold

artículo científico publicado en 2008

Photoreactivity of tiaprofenic acid and suprofen using pig skin as an ex vivo model

artículo científico publicado en 2000

Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro testing of the photoproducts of Butibufen and Flurbiprofen

artículo científico publicado en 1992

Plasma clearance, organ distribution and target cells of interleukin-6/hepatocyte-stimulating factor in the rat

artículo científico publicado en 1988

Polypodium leucotomos extract: antioxidant activity and disposition

artículo científico publicado en 2005

Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts

artículo científico publicado en 2006

Potential hepatoprotective effects of new Cuban natural products in rat hepatocytes culture

artículo científico publicado en 2008

Potentiation of cocaine hepatotoxicity by ethanol in human hepatocytes

artículo científico publicado en 1991

Potentiation of cocaine hepatotoxicity in human hepatocytes by ethanol

artículo científico publicado en 1992

Predicting drug-induced cholestasis: preclinical models

artículo científico publicado en 2018

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

artículo científico publicado en 2019

Preliminary results from the Scandinavian multicentre evaluation of in vitro cytotoxicity (MEIC)

artículo científico publicado en 1990

Primary photochemical processes of the phototoxic neuroleptic cyamemazine: a study by laser flash photolysis and steady-state irradiation.

artículo científico publicado en 2004

Primary steps of the photochemical reactions of 2-cyano-10-(3-[dimethylamino, N-oxide]-2-methylpropyl)-5-oxide-phenothiazine, the photoproduct of cyamemazine, a phototoxic neuroleptic: comparison with the sulfoxide

artículo científico publicado en 2006

Properties of P3 esters of nucleoside triphosphates as substrates for RNA polymerase from Escherichia coli.

artículo científico publicado en 1981

Quantification of CYP1A1 and 2B1/2 in rat hepatocytes cultured in microwells by immunological methods.

artículo científico publicado en 1994

Quantitative RT-PCR Measurement of Human Cytochrome P-450s: Application to Drug Induction Studies

artículo científico publicado en 2000

Rat hepatocytes cultured on a monkey kidney cell line: Expression of biotransformation and hepatic metabolic activities.

artículo científico publicado en 1991

Re-expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells

article

Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes

artículo científico publicado en 1988

Release of Inflammatory Mediators (PGE2, IL-6) by Fenofibric Acid-Photosensitized Human Keratinocytes and Fibroblasts

artículo científico publicado en 1998

Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes

article

Repression of the nuclear receptor small heterodimer partner by steatotic drugs and in advanced nonalcoholic fatty liver disease

artículo científico publicado en 2015

Role of glucose, insulin, and glucagon in glycogen mobilization in human hepatocytes.

artículo científico publicado en 1991

Role of hepatocyte nuclear factor 3 gamma in the expression of human CYP2C genes.

artículo científico publicado en 2004

S-adenosyl-L-methionine reverses the cholestatic effect of ethinylestradiol in rat hepatocytes by increasing its catabolism

scientific article published on 01 January 1992

Semi-automatic quantitative RT-PCR to measure CYP induction by drugs in human hepatocytes

artículo científico publicado en 2003

Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytes

artículo científico publicado en 2002

Sequential hepatogenic transdifferentiation of adipose tissue-derived stem cells: relevance of different extracellular signaling molecules, transcription factors involved, and expression of new key marker genes.

artículo científico publicado en 2009

Silencing of hepatic fate-conversion factors induce tumorigenesis in reprogrammed hepatic progenitor-like cells.

artículo científico publicado en 2016

Steatotic liver: a suitable source for the isolation of hepatic progenitor cells

artículo científico publicado en 2011

Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism: focus on in vitro studies.

artículo científico publicado en 2003

Synthesis of new, UV-photoactive dansyl derivatives for flow cytometric studies on bile acid uptake.

artículo científico publicado en 2009

Testing strategies for the safety of nanoparticles used in medical applications

artículo científico publicado en 2009

The Triplet Energy of Thymine in DNA

artículo científico publicado en 2006

The Use of Hepatocytes to Investigate Drug Toxicity

article

The Vitamin D Receptor Regulates Glycerolipid and Phospholipid Metabolism in Human Hepatocytes

scientific article published on 24 March 2020

The effects of buprenorphine on the metabolism of human hepatocytes.

artículo científico publicado en 1991

The hepatocyte growth factor regulates the synthesis of acute-phase proteins in human hepatocytes: Divergent effect on interleukin-6-stimulated genes

article

The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARα; and repressed by C/EBPα: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease

artículo científico publicado en 2013

The immunosuppressant drug FK506 prevents Fas-induced apoptosis in human hepatocytes

artículo científico publicado en 2004

The in vitro assessment of the toxicity of volatile, oxidisable, redox-cycling compounds: phenols as an example

artículo científico publicado en 2021

The use of cultured hepatocytes to investigate the mechanisms of drug hepatotoxicity.

artículo científico publicado en 1997

Toxic effects of the photoproducts of chlorpromazine on cultured hepatocytes

article

Toxicity of the antitumoral drug datelliptium in hepatic cells: Use of models in vitro for the prediction of toxicity in vivo.

artículo científico publicado en 1992

Transcriptional regulation and expression of CYP3A4 in hepatocytes.

artículo científico publicado en 2007

Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma

artículo científico publicado en 2003

Transcriptional regulation of the human hepatic CYP3A4: identification of a new distal enhancer region responsive to CCAAT/enhancer-binding protein beta isoforms (liver activating protein and liver inhibitory protein).

artículo científico publicado en 2005

Transplantation of hESC-derived hepatocytes protects mice from liver injury

artículo científico publicado en 2015

Triplet excited fluoroquinolones as mediators for thymine cyclobutane dimer formation in DNA.

artículo científico publicado en 2007

Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.

artículo científico publicado en 2006

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