Lista de obras - Holger Sültmann - Dominio Público Uruguay

A Cancer-Indicative microRNA Pattern in Normal Prostate Tissue.

artículo científico publicado en 2013

A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study.

artículo científico publicado en 2016

A field guide for cancer diagnostics using cell-free DNA: From principles to practice and clinical applications

artículo científico publicado en 2017

A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods ⬇️

artículo científico publicado el 15 de mayo de 2012

Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib

artículo científico publicado en 2014

Ago-RIP-Seq identifies Polycomb repressive complex I member CBX7 as a major target of miR-375 in prostate cancer progression

artículo científico publicado en 2016

Analysis of pigmented villonodular synovitis with genome-wide complementary DNA microarray and tissue array technology reveals insight into potential novel therapeutic approaches

artículo científico publicado en 2006

Antibody-mediated signal amplification for reverse phase protein array-based protein quantification

artículo científico publicado en 2011

BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence

artículo científico publicado en 2014

Characterization of transcriptional changes in ERG rearrangement-positive prostate cancer identifies the regulation of metabolic sensors such as neuropeptide Y.

artículo científico publicado en 2013

Circulating miRNAs are correlated with tumor progression in prostate cancer

scientific article published on 01 February 2011

Class I mhc genes of cichlid fishes: identification, expression, and polymorphism

artículo científico publicado en 1997

Combinatorial RNAi for quantitative protein network analysis

artículo científico publicado en 2007

Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling

artículo científico publicado en 2008

Correlation between genomic index lesions and mpMRI and Ga-PSMA-PET/CT imaging features in primary prostate cancer

artículo científico publicado en 2018

Cross-talk between AMPK and EGFR dependent Signaling in Non-Small Cell Lung Cancer.

artículo científico publicado en 2016

Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK+ Lung Cancer Patients with Poor Survival

artículo científico publicado en 2019

Die Urologie im Konzept der „Comprehensive Cancer Center“

artículo científico publicado en 2013

Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer

artículo científico publicado en 2009

Digital PCR After MALDI-Mass Spectrometry Imaging to Combine Proteomic Mapping and Identification of Activating Mutations in Pulmonary Adenocarcinoma

scientific article published on 15 October 2018

Discrimination of direct and indirect interactions in a network of regulatory effects

artículo científico publicado en 2007

ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction.

artículo científico publicado en 2010

EZH2 depletion blocks the proliferation of colon cancer cells

artículo científico publicado en 2011

Early detection of lung cancer by molecular markers in endobronchial epithelial-lining fluid

artículo científico publicado en 2012

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer

artículo científico publicado en 2008

Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance

artículo científico publicado en 2018

Equivalence test in quantitative reverse transcription polymerase chain reaction: confirmation of reference genes suitable for normalization

scientific article published on 01 December 2004

Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue.

artículo científico publicado en 2012

Estimating large-scale signaling networks through nested effect models with intervention effects from microarray data

artículo científico publicado en 2008

Evolving therapeutic concepts in prostate cancer based on genome-wide analyses (review).

artículo científico publicado en 2014

Experimental design and data analysis of Ago-RIP-Seq experiments for the identification of microRNA targets

artículo científico publicado en 2017

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment.

artículo científico publicado en 2015

Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation

artículo científico publicado en 2014

FGF-2 is a driving force for chromosomal instability and a stromal factor associated with adverse clinico-pathological features in prostate cancer

artículo científico publicado en 2018

From ORFeome to biology: a functional genomics pipeline

artículo científico publicado en 2004

Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle

artículo científico publicado en 2005

Gene expression analysis of endobronchial epithelial lining fluid in the evaluation of indeterminate pulmonary nodules

artículo científico publicado en 2009

Gene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosis

artículo científico publicado en 2012

Genome-Based Classification and Therapy of Prostate Cancer

artículo científico publicado en 2018

Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation

artículo científico publicado en 2012

Genomic analysis reveals poor separation of human cardiomyopathies of ischemic and nonischemic etiologies

artículo científico publicado en 2008

Genomic features of renal cell carcinoma with venous tumor thrombus

artículo científico publicado en 2018

Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas

article

Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes

artículo científico publicado en 2008

Graph based fusion of miRNA and mRNA expression data improves clinical outcome prediction in prostate cancer

artículo científico publicado en 2011

Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes.

artículo científico

Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes.

artículo científico publicado en 2018

Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer

artículo científico publicado en 2006

Identification and validation of clinically relevant molecular alterations in prostate cancer

artículo científico publicado en 2009

Identification and validation of clinically relevant molecular alterations in prostate cancer

artículo científico publicado en 2008

Identification of E6/E7-Dependent MicroRNAs in HPV-Positive Cancer Cells.

artículo científico publicado en 2018

Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer

artículo científico publicado en 2007

Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analyses

artículo científico publicado en 2007

Identification of clinically relevant protein targets in prostate cancer with 2D-DIGE coupled mass spectrometry and systems biology network platform

artículo científico publicado en 2011

In vitro-targeted gene identification in patients with hepatitis C using a genome-wide microarray technology

artículo científico publicado en 2009

Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions.

artículo científico publicado en 2008

Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification

artículo científico publicado en 2010

Infrared-based protein detection arrays for quantitative proteomics

artículo científico publicado en 2008

Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients

artículo científico publicado en 2010

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

artículo científico publicado en 2013

Intratumorale Heterogenität des Nierenzellkarzinoms

artículo científico publicado en 2015

Isolation of mhc class II DMA and DMB cDNA sequences in a marsupial: the gray short-tailed opossum (Monodelphis domestica)

artículo científico publicado en 1998

Long noncoding RNA: "LNCs" to cancer

artículo científico publicado en 2014

Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs).

artículo científico publicado en 2008

Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage

artículo científico publicado en 2011

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients

artículo científico publicado en 2016

Major histocompatibility complex class II A genes in cichlid fishes: identification, expression, linkage relationships, and haplotype variation.

artículo científico publicado en 2000

Metastases and multiple myeloma generate distinct transcriptional footprints in osteocytes in vivo

artículo científico publicado en 2008

Mhc class I gene of African lungfish

artículo científico publicado en 2000

Mhc class II B gene evolution in East African cichlid fishes

artículo científico publicado en 2000

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

artículo científico publicado en 2018

Molecular cancer phenotype in normal prostate tissue

artículo científico publicado en 2008

Molecular signatures in IASLC/ATS/ERS classified growth patterns of lung adenocarcinoma

artículo científico publicado en 2018

Mutation analysis of circulating plasma DNA to determine response to EGFR tyrosine kinase inhibitor therapy of lung adenocarcinoma patients

artículo científico publicado en 2016

Mutations in BRCA2 and taxane resistance in prostate cancer

artículo científico publicado en 2017

New family of Mhc class II A genes identified from cDNA sequences in the cichlid fish Aulonocara hansbaenschi.

artículo científico publicado en 1999

Next generation sequencing of the cellular and liquid fraction of pancreatic cyst fluid supports discrimination of IPMN from pseudocysts and reveals cases with multiple mutated driver clones: First findings from the prospective ZYSTEUS biomarker stu

artículo científico publicado en 2018

Nonlinkage of major histocompatibility complex class I and class II loci in bony fishes

artículo científico publicado en 2000

Novel RNA markers in prostate cancer: functional considerations and clinical translation

artículo científico publicado en 2014

Organization of Mhc class II B genes in the zebrafish (Brachydanio rerio).

artículo científico publicado en 1994

PARP inhibition in BRCA2-mutated prostate cancer

artículo científico publicado en 2017

Pathways regulating the expression of the immunomodulatory protein glycodelin in non‑small cell lung cancer

article

Patient-specific molecular alterations are associated with metastatic clear cell renal cell cancer progressing under tyrosine kinase inhibitor therapy.

artículo científico publicado en 2017

Peroxiredoxins 3 and 4 Are Overexpressed in Prostate Cancer Tissue and Affect the Proliferation of Prostate Cancer Cells in Vitro ⬇️

artículo científico publicado el 28 de marzo de 2012

Polymorphism and estimation of the number of MhcCyca class I and class II genes in laboratory strains of the common carp (Cyprinus carpio L.).

artículo científico publicado en 1993

Predicting pathway membership via domain signatures.

artículo científico publicado en 2008

Prognostic role of E2F1 and members of the CDKN2A network in gastrointestinal stromal tumors.

artículo científico publicado en 2005

QSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments

artículo científico publicado en 2016

Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells

artículo científico publicado en 2008

Reverse-phase protein arrays for application-orientated cancer research

artículo científico publicado en 2009

Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma

artículo científico publicado en 2014

Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics

artículo científico publicado en 2010

Serial liquid biopsies for detection of treatment failure and profiling of resistance mechanisms in KLC1-ALK-rearranged lung cancer

scientific article published on 13 December 2019

Serum miR-142-3p is associated with early relapse in operable lung adenocarcinoma patients

artículo científico publicado en 2013

Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity

artículo científico publicado en 2016

Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers

artículo científico publicado en 2007

Systematic analysis of T7 RNA polymerase based in vitro linear RNA amplification for use in microarray experiments

artículo científico publicado en 2004

TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.

artículo científico publicado en 2011

TMPRSS2:ERG gene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells

artículo científico publicado en 2017

Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

artículo científico publicado en 2011

The ERG-regulated LINC00920 promotes prostate cancer cell survival via the 14-3-3ε- FOXO pathway

scientific article published on 09 July 2020

The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection.

artículo científico publicado en 2010

The differentiation antigen NY-BR-1 is a potential target for antibody-based therapies in breast cancer

artículo científico publicado en 2007

The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.

artículo científico publicado en 2007

The maternal embryonic leucine zipper kinase (MELK) is upregulated in high-grade prostate cancer ⬇️

artículo científico publicado el 4 de septiembre de 2012

Transcription alterations of members of the ubiquitin-proteasome network in prostate carcinoma.

artículo científico publicado en 2010

[Gene expression profiling in lung cancer. Experimental research and clinical application]

artículo científico publicado en 2009

[Microarrays for the identification of molecular markers in the diagnosis and therapy of renal cell carcinomas]

artículo científico publicado en 2006

[Molecular high throughput research in prostate carcinoma]

artículo científico publicado en 2007

arrayMagic: two-colour cDNA microarray quality control and preprocessing

artículo científico publicado en 2004

microRNA biomarkers in body fluids of prostate cancer patients ⬇️

artículo científico publicado el 29 de mayo de 2012

pathClass: an R-package for integration of pathway knowledge into support vector machines for biomarker discovery

artículo científico publicado en 2011

Lista de obras de Holger Sültmann

A Cancer-Indicative microRNA Pattern in Normal Prostate Tissue.

A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study.

A field guide for cancer diagnostics using cell-free DNA: From principles to practice and clinical applications

A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods ⬇️

Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib

Ago-RIP-Seq identifies Polycomb repressive complex I member CBX7 as a major target of miR-375 in prostate cancer progression

Analysis of pigmented villonodular synovitis with genome-wide complementary DNA microarray and tissue array technology reveals insight into potential novel therapeutic approaches

Antibody-mediated signal amplification for reverse phase protein array-based protein quantification

BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence

Characterization of transcriptional changes in ERG rearrangement-positive prostate cancer identifies the regulation of metabolic sensors such as neuropeptide Y.

Circulating miRNAs are correlated with tumor progression in prostate cancer

Class I mhc genes of cichlid fishes: identification, expression, and polymorphism

Combinatorial RNAi for quantitative protein network analysis

Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling

Correlation between genomic index lesions and mpMRI and Ga-PSMA-PET/CT imaging features in primary prostate cancer

Cross-talk between AMPK and EGFR dependent Signaling in Non-Small Cell Lung Cancer.

Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK+ Lung Cancer Patients with Poor Survival

Die Urologie im Konzept der „Comprehensive Cancer Center“

Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer

Digital PCR After MALDI-Mass Spectrometry Imaging to Combine Proteomic Mapping and Identification of Activating Mutations in Pulmonary Adenocarcinoma

Discrimination of direct and indirect interactions in a network of regulatory effects

ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction.

EZH2 depletion blocks the proliferation of colon cancer cells

Early detection of lung cancer by molecular markers in endobronchial epithelial-lining fluid

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer

Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance

Equivalence test in quantitative reverse transcription polymerase chain reaction: confirmation of reference genes suitable for normalization

Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue.

Estimating large-scale signaling networks through nested effect models with intervention effects from microarray data

Evolving therapeutic concepts in prostate cancer based on genome-wide analyses (review).

Experimental design and data analysis of Ago-RIP-Seq experiments for the identification of microRNA targets

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment.

Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation

FGF-2 is a driving force for chromosomal instability and a stromal factor associated with adverse clinico-pathological features in prostate cancer

From ORFeome to biology: a functional genomics pipeline

Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle

Gene expression analysis of endobronchial epithelial lining fluid in the evaluation of indeterminate pulmonary nodules

Gene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosis

Genome-Based Classification and Therapy of Prostate Cancer

Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation

Genomic analysis reveals poor separation of human cardiomyopathies of ischemic and nonischemic etiologies

Genomic features of renal cell carcinoma with venous tumor thrombus

Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas

Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes

Graph based fusion of miRNA and mRNA expression data improves clinical outcome prediction in prostate cancer

Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes.

Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes.

Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer

Identification and validation of clinically relevant molecular alterations in prostate cancer

Identification and validation of clinically relevant molecular alterations in prostate cancer

Identification of E6/E7-Dependent MicroRNAs in HPV-Positive Cancer Cells.

Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer

Identification of cellular targets for the human papillomavirus E6 and E7 oncogenes by RNA interference and transcriptome analyses

Identification of clinically relevant protein targets in prostate cancer with 2D-DIGE coupled mass spectrometry and systems biology network platform

In vitro-targeted gene identification in patients with hepatitis C using a genome-wide microarray technology

Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions.

Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification

Infrared-based protein detection arrays for quantitative proteomics

Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

Intratumorale Heterogenität des Nierenzellkarzinoms

Isolation of mhc class II DMA and DMB cDNA sequences in a marsupial: the gray short-tailed opossum (Monodelphis domestica)

Long noncoding RNA: "LNCs" to cancer

Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs).

Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients

Major histocompatibility complex class II A genes in cichlid fishes: identification, expression, linkage relationships, and haplotype variation.

Metastases and multiple myeloma generate distinct transcriptional footprints in osteocytes in vivo

Mhc class I gene of African lungfish

Mhc class II B gene evolution in East African cichlid fishes

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

Molecular cancer phenotype in normal prostate tissue

Molecular signatures in IASLC/ATS/ERS classified growth patterns of lung adenocarcinoma

Mutation analysis of circulating plasma DNA to determine response to EGFR tyrosine kinase inhibitor therapy of lung adenocarcinoma patients

Mutations in BRCA2 and taxane resistance in prostate cancer

New family of Mhc class II A genes identified from cDNA sequences in the cichlid fish Aulonocara hansbaenschi.

Next generation sequencing of the cellular and liquid fraction of pancreatic cyst fluid supports discrimination of IPMN from pseudocysts and reveals cases with multiple mutated driver clones: First findings from the prospective ZYSTEUS biomarker stu

Nonlinkage of major histocompatibility complex class I and class II loci in bony fishes

Novel RNA markers in prostate cancer: functional considerations and clinical translation