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Lista de obras de Stephan Ludwig

3-O-galloylated procyanidins from Rumex acetosa L. inhibit the attachment of influenza A virus

artículo científico publicado en 2014

3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways

artículo científico publicado en 1996

A Single Point Mutation (Y89F) within the Non-Structural Protein 1 of Influenza A Viruses Limits Epithelial Cell Tropism and Virulence in Mice

article by Eike R. Hrincius et al published June 2012 in The American Journal of Pathology

A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway

artículo científico publicado en 2009

A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication

artículo científico publicado en 2011

A plant extract of Ribes nigrum folium possesses anti-influenza virus activity in vitro and in vivo by preventing virus entry to host cells

artículo científico publicado en 2013

A polyphenol rich plant extract, CYSTUS052, exerts anti influenza virus activity in cell culture without toxic side effects or the tendency to induce viral resistance

artículo científico publicado en 2007

A reassortant H1N1 influenza A virus caused fatal epizootics among camels in Mongolia

artículo científico publicado en 1993

Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappaB-inhibiting activity

artículo científico publicado en 2007

Activation of Cardiac c-Jun NH 2 -Terminal Kinases and p38-Mitogen–Activated Protein Kinases With Abrupt Changes in Hemodynamic Load

artículo científico publicado en 2001

Activation of MAP kinase p38 is critical for the cell-cycle-controlled suppressor function of regulatory T cells

Activation of NF-kappaB by IL-1beta blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human gamma-fibrinogen gene

artículo científico publicado en 2007

Activation of NF-κB via the IκB Kinase Complex Is Both Essential and Sufficient for Proinflammatory Gene Expression in Primary Endothelial Cells

artículo científico publicado en 2001

Activation of c-jun N-terminal kinase upon influenza A virus (IAV) infection is independent of pathogen-related receptors but dependent on amino acid sequence variations of IAV NS1.

artículo científico publicado en 2014

Activation of phosphatidylinositol 3-kinase signaling by the nonstructural NS1 protein is not conserved among type A and B influenza viruses

artículo científico publicado en 2007

Advances in Transgenic Mouse Models to Study Infections by Human Pathogenic Viruses

scientific article published on 05 December 2020

Agonists of proteinase-activated receptor-2 enhance IFN-gamma-inducible effects on human monocytes: role in influenza A infection

artículo científico publicado en 2008

Amino acid replacements leading to temperature-sensitive defects of the NS1 protein of influenza A virus

artículo científico publicado en 1995

Analysis of influenza A virus nucleoproteins for the assessment of molecular genetic mechanisms leading to new phylogenetic virus lineages.

artículo científico publicado en 1993

Annexin A6-balanced late endosomal cholesterol controls influenza A replication and propagation

artículo científico publicado en 2013

Antigenic and genetic analyses of H1N1 influenza A viruses from European pigs

artículo científico publicado en 1997

Antiviral activity of Ladania067, an extract from wild black currant leaves against influenza A virus in vitro and in vivo

artículo científico publicado en 2014

Antiviral activity of hydroalcoholic extract from Eupatorium perfoliatum L. against the attachment of influenza A virus

artículo científico publicado en 2016

Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo

artículo científico publicado en 2011

Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities

scientific article published on 01 January 2019

Apoptosis leads to a degradation of vital components of active nuclear transport and a dissociation of the nuclear lamina

artículo científico publicado en 2008

Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury

artículo científico

Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation

artículo científico publicado en 2018

Automated scalable modeling for population microsimulations

Avian influenza viruses inhibit the major cellular signalling integrator c-Abl

artículo científico publicado en 2014

Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence

artículo científico publicado en 2006

Borna disease virus nucleoprotein interacts with the CDC2-cyclin B1 complex

artículo científico publicado en 2003

CRK adaptor protein expression is required for efficient replication of avian influenza A viruses and controls JNK-mediated apoptotic responses

artículo científico publicado en 2010

CYSTUS052, a polyphenol-rich plant extract, exerts anti-influenza virus activity in mice.

artículo científico publicado en 2007

Capability of the viral NS1 proteins to bind to the cellular adaptor proteins Crk and CrkL determines sensitivity of influenza viruses to Crk/CrkL expression

artículo científico publicado en 2009

Cascading towards vascular disorder gene therapy

artículo científico publicado en 1995

Caspase 3 activation is essential for efficient influenza virus propagation

artículo científico publicado en 2003

Caspase inhibition activates HIV in latently infected cells. Role of tumor necrosis factor receptor 1 and CD95.

artículo científico publicado en 2002

Caspase inhibitors as a supplement in immune activation therapies to achieve eradication of HIV in its latent reservoirs

artículo científico publicado en 2003

Cloning and characterization of RLPK, a novel RSK-related protein kinase

artículo científico publicado en 1999

Combined action of influenza virus and Staphylococcus aureus panton-valentine leukocidin provokes severe lung epithelium damage ⬇️

artículo científico publicado en 2012

Constitutive activation of the transcription factor NF-kappaB results in impaired borna disease virus replication

artículo científico publicado en 2005

Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549.

artículo científico publicado en 2016

Deficiency in the LIM-only protein FHL2 impairs assembly of extracellular matrix proteins

artículo científico publicado en 2008

Deficiency of Fhl2 leads to delayed neuronal cell migration and premature astrocyte differentiation

artículo científico publicado en 2019

Der Pflanzenextrakt Cystus052 blockiert Grippeviren

Derivation of the nucleoproteins (NP) of influenza A viruses isolated from marine mammals.

artículo científico publicado en 1990

Differences in cell activation by Chlamydophila pneumoniae and Chlamydia trachomatis infection in human endothelial cells

artículo científico publicado en 2004

Different Mitogen-activated Protein Kinase Signaling Pathways Cooperate to Regulate Tumor Necrosis Factor α Gene Expression in T Lymphocytes

artículo científico publicado en 1999

Discrete spatio-temporal regulation of tyrosine phosphorylation directs influenza A virus M1 protein towards its function in virion assembly

scientific article published on 31 August 2020

Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections ⬇️

artículo científico publicado el 1 de octubre de 2011

Doxycycline-induced expression of transgenic human tumor necrosis factor α in adult mice results in psoriasis-like arthritis

artículo científico publicado en 2013

Dual function of interleukin-1beta for the regulation of interleukin-6-induced suppressor of cytokine signaling 3 expression

artículo científico publicado en 2004

Employing RNA viruses to fight cancer: novel insights into oncolytic virotherapy

artículo científico publicado en 2017

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

artículo científico publicado en 2010

Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome

artículo científico publicado en 2009

European swine virus as a possible source for the next influenza pandemic?

artículo científico publicado en 1995

Evidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein

artículo científico publicado en 2015

Exploited defense: how influenza viruses take advantage of antiviral signaling responses

article

Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells

artículo científico publicado en 2001

FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis

artículo científico publicado en 2014

Genetics, evolution, and the zoonotic capacity of European Swine influenza viruses

artículo científico publicado en 2013

H5N1 virus activates signaling pathways in human endothelial cells resulting in a specific imbalanced inflammatory response

artículo científico publicado en 2010

High level expression of the anti-retroviral protein APOBEC3G is induced by influenza A virus but does not confer antiviral activity

artículo científico publicado en 2009

Highlight – Viruses and Signaling

artículo científico publicado en 2008

Highly pathogenic avian influenza viruses inhibit effective immune responses of human blood-derived macrophages

artículo científico publicado en 2012

Highly pathogenic influenza viruses inhibit inflammatory response in monocytes via activation of rar-related orphan receptor RORα.

artículo científico publicado en 2013

Homocysteine inhibits tumor necrosis factor-induced activation of endothelium via modulation of nuclear factor-kappa b activity

artículo científico publicado en 2001

Hypoxia/reoxygenation induction of monocyte chemoattractant protein-1 in melanoma cells: involvement of nuclear factor-kappaB, stimulatory protein-1 transcription factors and mitogen-activated protein kinase pathways

artículo científico publicado en 2002

Identification and characterisation of novel Mss4-binding Rab GTPases

artículo científico publicado en 2011

Immunomodulatory Nonstructural Proteins of Influenza A Viruses

artículo científico publicado en 2018

Impact of <i>Staphylococcus aureus</i> Small Colony Variants on Human Lung Epithelial Cells with Subsequent Influenza Virus Infection

artículo científico publicado en 2020

In Vitro Models to Study Influenza Virus and Staphylococcus aureus Super-Infection on a Molecular Level

In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B

artículo científico publicado en 2015

Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses

artículo científico publicado en 2007

Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked

artículo científico publicado en 2017

Influenza A virus TRIMs the type I interferon response

artículo científico publicado en 2009

Influenza A virus does not encode a tetherin antagonist with Vpu-like activity and induces IFN-dependent tetherin expression in infected cells

artículo científico publicado en 2012

Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression

artículo científico publicado en 2008

Influenza A viruses suppress cyclooxygenase-2 expression by affecting its mRNA stability

artículo científico publicado en 2016

Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade

artículo científico publicado en 2001

Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway

artículo científico publicado en 2001

Influenza virus-induced NF-kappaB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IkappaB kinase

artículo científico publicado en 2000

Influenza viruses and MAP kinase cascades – Novel targets for an antiviral intervention?

scholarly article by Stephan Ludwig published in February 2007

Influenza viruses and the NF-kappaB signaling pathway - towards a novel concept of antiviral therapy

artículo científico publicado en 2008

Influenza viruses control the vertebrate type I interferon system: factors, mechanisms, and consequences

artículo científico publicado en 2009

Influenza, a One Health paradigm--novel therapeutic strategies to fight a zoonotic pathogen with pandemic potential.

artículo científico publicado en 2014

Influenza-virus-induced signaling cascades: targets for antiviral therapy?

artículo científico publicado en 2003

Inhibition of p38 mitogen-activated protein kinase impairs influenza virus-induced primary and secondary host gene responses and protects mice from lethal H5N1 infection

artículo científico publicado en 2013

Interaction between S100A8/A9 and annexin A6 is involved in the calcium-induced cell surface exposition of S100A8/A9.

artículo científico publicado en 2008

Interaction of influenza A virus matrix protein with RACK1 is required for virus release

artículo científico publicado en 2012

Interleukin-27 displays interferon-gamma-like functions in human hepatoma cells and hepatocytes

artículo científico publicado en 2009

Interplay between influenza A virus and the innate immune signaling

scientific article published on 25 September 2009

Introduction of silent mutations into the NP gene of influenza A viruses as a possible strategy for the creation of a live attenuated vaccine

artículo científico publicado en 2012

Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus

artículo científico publicado en 2018

Late activation of the Raf/MEK/ERK pathway is required for translocation of the respiratory syncytial virus F protein to the plasma membrane and efficient viral replication

artículo científico publicado en 2018

Lung-specific expression of active Raf kinase results in increased mortality of influenza A virus-infected mice

artículo científico publicado en 2004

MAP kinase-activated protein kinases 2 and 3 are required for influenza A virus propagation and act via inhibition of PKR.

artículo científico publicado en 2010

MAPKAP kinase 3 suppresses Ifng gene expression and attenuates NK cell cytotoxicity and Th1 CD4 T-cell development upon influenza A virus infection

artículo científico publicado en 2014

MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1

artículo científico publicado en 2005

MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination

artículo científico publicado en 2022

MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling

artículo científico publicado en 2019

MEK inhibition impairs influenza B virus propagation without emergence of resistant variants

artículo científico publicado en 2004

MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells

artículo científico publicado en 2001

MEK5/ERK5 signaling modulates endothelial cell migration and focal contact turnover

artículo científico publicado en 2009

MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes

artículo científico publicado en 2004

Macrophage-mediated psoriasis can be suppressed by regulatory T lymphocytes

artículo científico publicado en 2016

Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling

artículo científico publicado en 2006

Metabolic conversion of CI-1040 turns a cellular MEK-inhibitor into an antibacterial compound.

artículo científico publicado en 2018

Mitogen-activated 3p kinase is active in the nucleus

artículo científico publicado en 2004

Mitogen-activated protein kinases (MAPKs) regulate IL-6 over-production during concomitant influenza virus and Staphylococcus aureus infection

artículo científico publicado en 2017

Monoclonal antibodies against the PB1-F2 protein of H1N1 influenza A virus

artículo científico publicado en 2010

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

artículo científico publicado en 2007

Mss4 protein is a regulator of stress response and apoptosis

artículo científico publicado en 2012

Multiple signaling pathways regulate NF-kappaB-dependent transcription of the monocyte chemoattractant protein-1 gene in primary endothelial cells

article

NF-kappaB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation

artículo científico publicado en 2004

Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death

artículo científico publicado en 2001

New virulence determinants contribute to the enhanced immune response and reduced virulence of an influenza A virus A/PR8/34 variant

artículo científico publicado en 2013

Nonstructural protein 1 (NS1)-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections: insights into 1918 H1N1 pandemic?

artículo científico publicado en 2014

Oncolytic influenza virus infection restores immunocompetence of lung tumor-associated alveolar macrophages

artículo científico publicado en 2018

Origin of the 1918 pandemic H1N1 influenza A virus as studied by codon usage patterns and phylogenetic analysis

artículo científico publicado en 2010

PAR1 contributes to influenza A virus pathogenicity in mice

artículo científico publicado en 2012

PD-1 IC Inhibition Synergistically Improves Influenza A Virus-Mediated Oncolysis of Metastatic Pulmonary Melanoma

scientific article published on 08 April 2020

Pathogenesis of Staphylococcus aureus necrotizing pneumonia: the role of PVL and an influenza coinfection.

artículo científico publicado en 2013

Pathogenicity of different PR8 influenza A virus variants in mice is determined by both viral and host factors

artículo científico publicado en 2011

Pharmacodynamics, Pharmacokinetics, and Antiviral Activity of BAY 81-8781, a Novel NF-κB Inhibiting Anti-influenza Drug

artículo científico publicado en 2017

Phosphatidylinositol-3-kinase (PI3K) is activated by influenza virus vRNA via the pathogen pattern receptor Rig-I to promote efficient type I interferon production

artículo científico publicado en 2011

Phosphorylation of JIP4 at S730 Presents Antiviral Properties against Influenza A Virus Infection

artículo científico publicado en 2021

Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells

artículo científico publicado en 2018

Phosphorylation of influenza A virus NS1 at serine 205 mediates its viral polymerase-enhancing function

scientific article published on 06 January 2021

Phosphorylation of influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity

artículo científico publicado en 2015

Phosphorylation of the influenza A virus protein PB1-F2 by PKC is crucial for apoptosis promoting functions in monocytes.

artículo científico publicado en 2009

Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses ⬇️

artículo científico publicado el 1 de agosto de 1991

Platelet activation and aggregation promote lung inflammation and influenza virus pathogenesis.

artículo científico publicado en 2015

Polyethylenimine, a cost-effective transfection reagent

scholarly article by Christina Ehrhardt published in June 2006

Previous H1N1 influenza A viruses circulating in the Mongolian population.

artículo científico publicado en 1996

Proliferative Inhibition and Apoptotic Mechanism on Human Non-small-cell Lung Cancer (A549 Cells) of a Novel Cucurbitacin from Wilbrandia ebracteata Cogn

Proteinase-activated receptor-2 agonist activates anti-influenza mechanisms and modulates IFNγ-induced antiviral pathways in human neutrophils.

artículo científico publicado en 2013

Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3.

artículo científico publicado en 2004

Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases

artículo científico publicado en 2022

Ras-independent Activation of the Raf/MEK/ERK Pathway upon Calcium-induced Differentiation of Keratinocytes

scientific article published in Journal of Biological Chemistry

Recent influenza A (H1N1) infections of pigs and turkeys in northern Europe

artículo científico publicado en 1994

Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells

artículo científico publicado en 2006

Role of proteinase-activated receptor-2 in anti-bacterial and immunomodulatory effects of interferon-γ on human neutrophils and monocytes

artículo científico publicado en 2011

Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles

article published in 2001

Semisynthetic Cardenolides Acting as Antiviral Inhibitors of Influenza A Virus Replication by Preventing Polymerase Complex Formation

artículo científico publicado en 2020

Sequence of the nucleoprotein (NP) gene of the influenza Alanas acuta/Primorje/695/76 (H2N3) virus

artículo científico publicado en 1991

Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activity

artículo científico publicado en 2000

Signaling to Life and Death: Influenza Viruses and Intracellular Signal Transduction Cascades

Small Spleen Peptides (SSPs) Shape Dendritic Cell Differentiation through Modulation of Extracellular ATP Synthesis Profile

artículo científico publicado en 2024

Small molecule inhibitors of the c-Jun N-terminal kinase (JNK) possess antiviral activity against highly pathogenic avian and human pandemic influenza A viruses

artículo científico publicado en 2012

Staphylococcus aureus triggers a shift from influenza virus-induced apoptosis to necrotic cell death

artículo científico publicado en 2018

Super-infection with Staphylococcus aureus inhibits influenza virus-induced type I IFN signalling through impaired STAT1-STAT2 dimerization

artículo científico publicado en 2014

Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice

artículo científico publicado en 2011

Targeting a metabolic pathway to fight the flu.

artículo científico publicado en 2017

Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy

artículo científico publicado en 2009

Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy

article by Stephan Ludwig published 6 May 2009 in Journal of Antimicrobial Chemotherapy

Targeting intracellular signaling as an antiviral strategy: aerosolized LASAG for the treatment of influenza in hospitalized patients

artículo científico publicado en 2018

Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine

scientific article published on 25 September 2020

The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription When Associated with Specific Structures in the Nucleus

artículo científico publicado en 2021

The LIM-Only Protein Four and a Half LIM Domain Protein 2 Attenuates Development of Psoriatic Arthritis by Blocking Adam17-Mediated Tumor Necrosis Factor Release

artículo científico publicado en 2017

The LIM-only protein FHL2 attenuates lung inflammation during bleomycin-induced fibrosis

artículo científico publicado en 2013

The LIM-only protein FHL2 supports influenza A virus-induced lung inflammation by restricting the host adaptive immune response

artículo científico publicado en 2018

The MEK-inhibitor CI-1040 displays a broad anti-influenza virus activity in vitro and provides a prolonged treatment window compared to standard of care in vivo

artículo científico publicado en 2017

The MKK6/p38 mitogen-activated protein kinase pathway is capable of inducing SOCS3 gene expression and inhibits IL-6-induced transcription

artículo científico publicado en 2001

The Mitogen-activated Protein (MAP) Kinase p38 and Its Upstream Activator MAP Kinase Kinase 6 Are Involved in the Activation of Signal Transducer and Activator of Transcription by Hyperosmolarity

artículo científico publicado en 1999

The NF-kappaB inhibitor SC75741 protects mice against highly pathogenic avian influenza A virus

artículo científico publicado en 2013

The NF-κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance

artículo científico publicado en 2013

The NS segment of an H5N1 highly pathogenic avian influenza virus (HPAIV) is sufficient to alter replication efficiency, cell tropism, and host range of an H7N1 HPAIV

artículo científico publicado en 2009

The NS1 protein of influenza A virus blocks RIG-I-mediated activation of the noncanonical NF-κB pathway and p52/RelB-dependent gene expression in lung epithelial cells

artículo científico publicado en 2012

The Rac1 inhibitor NSC23766 exerts anti-influenza virus properties by affecting the viral polymerase complex activity.

artículo científico publicado en 2014

The Two Sides of the Same Coin-Influenza Virus and Intracellular Signal Transduction

scientific article published on 30 December 2019

The Vesicular Stomatitis Virus Matrix Protein Inhibits Glycoprotein 130-Dependent STAT Activation ⬇️

artículo científico publicado el 1 de noviembre de 2001

The adaptor protein FHL2 enhances the cellular innate immune response to influenza A virus infection

artículo científico publicado en 2012

The annexin A1/FPR2 signaling axis expands alveolar macrophages, limits viral replication, and attenuates pathogenesis in the murine influenza A virus infection model

artículo científico publicado en 2019

The binding of Mss4 to alpha-integrin subunits regulates matrix metalloproteinase activation and fibronectin remodeling

artículo científico publicado en 2006

The clinically approved MEK inhibitor Trametinib efficiently blocks influenza A virus propagation and cytokine expression

scholarly article by Tobias Schräder published in September 2018

The clinically approved proteasome inhibitor PS-341 efficiently blocks influenza A virus and vesicular stomatitis virus propagation by establishing an antiviral state

artículo científico publicado en 2010

The clinically licensed antifungal drug itraconazole inhibits influenza virus in vitro and in vivo

artículo científico publicado en 2019

The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells

artículo científico publicado en 2010

The human H3N2 influenza viruses A/Victoria/3/75 and A/Hiroshima/52/2005 preferentially bind to α2-3-sialylated monosialogangliosides with fucosylated poly-N-acetyllactosaminyl chains

artículo científico publicado en 2012

The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors

artículo científico publicado en 2002

The influenza A virus matrix protein as a marker to monitor initial virus internalisation

artículo científico publicado en 2009

The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections

artículo científico publicado en 2020

The influenza virus PB1-F2 protein has interferon antagonistic activity

artículo científico publicado en 2011

The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein

artículo científico publicado en 2008

The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway

artículo científico publicado en 1998

Transactivation of naturally occurring HIV-1 long terminal repeats by the JNK signaling pathway. The most frequent naturally occurring length polymorphism sequence introduces a novel binding site for AP-1 factors

artículo científico publicado en 2000

Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells

artículo científico publicado en 2004

Type I interferon antagonistic properties of influenza B virus polymerase proteins

scientific article published on 08 December 2019

Vemurafenib Limits Influenza A Virus Propagation by Targeting Multiple Signaling Pathways

artículo científico publicado en 2017

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions

artículo científico publicado en 2014

Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1.

artículo científico publicado en 2005

Virus Infection and Systemic Inflammation: Lessons Learnt from COVID-19 and Beyond

artículo científico publicado en 2022

Will omics help to cure the flu?

artículo científico publicado en 2014

β-catenin promotes the type I IFN synthesis and the IFN-dependent signaling response but is suppressed by influenza A virus-induced RIG-I/NF-κB signaling

artículo científico publicado en 2014

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