Lista de obras - Christoph Romanin - Dominio Público Uruguay

2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size.

artículo científico publicado en 2008

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

artículo científico publicado en 2009

A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription

artículo científico publicado en 2015

A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).

artículo científico publicado en 2014

A dual mechanism promotes switching of the Stormorken STIM1 R304W mutant into the activated state.

artículo científico publicado en 2018

A novel homology model of TRPC3 reveals allosteric coupling between gate and selectivity filter.

artículo científico publicado en 2013

A sequence in the carboxy-terminus of the alpha(1C) subunit important for targeting, conductance and open probability of L-type Ca(2+) channels.

artículo científico publicado en 2000

A type 2A phosphatase-sensitive phosphorylation site controls modal gating of L-type Ca2+ channels in human vascular smooth-muscle cells.

artículo científico publicado en 1996

ATP-induced activation of expressed RyR3 at low free calcium.

artículo científico publicado en 2000

Action of calpastatin in prevention of cardiac L-type Ca2+ channel run-down cannot be mimicked by synthetic calpain inhibitors

scientific article published on 01 February 1995

Activity of cardiac L-type Ca2+ channels is sensitive to cytoplasmic calcium

artículo científico publicado en 1992

Adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene.

artículo científico publicado en 2003

Adhesion and proliferation of human vascular cells on UV-light-modified polymers

artículo científico publicado en 2004

An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel

artículo científico publicado en 2018

Assembly domains in TRP channels.

artículo científico publicado en 2007

Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N-terminus.

artículo científico publicado en 2017

Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry

artículo científico publicado en 2011

Basal dephosphorylation controls slow gating of L-type Ca2+ channels in human vascular smooth muscle.

artículo científico publicado en 1995

C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels

artículo científico publicado en 2006

CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions

scientific article published on 22 December 2020

CRAC inhibitors: identification and potential

artículo científico publicado en 2008

Ca(2+) release-activated Ca(2+) (CRAC) current, structure, and function.

artículo científico publicado en 2012

Ca(2+) sensors of L-type Ca(2+) channel

artículo científico publicado en 2000

Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger.

artículo científico publicado en 2004

CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells.

artículo científico publicado en 2004

Calpastatin and nucleotides stabilize cardiac calcium channel activity in excised patches

artículo científico publicado en 1991

Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.

artículo científico publicado en 2012

Cell adhesion on polytetrafluoroethylene modified by UV-irradiation in an ammonia atmosphere.

artículo científico publicado en 2003

Cell microarrays on photochemically modified polytetrafluoroethylene

artículo científico publicado en 2005

Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction

artículo científico publicado en 2010

Cellular cholesterol controls TRPC3 function: evidence from a novel dominant-negative knockdown strategy.

artículo científico publicado en 2006

Cholesterol modulates Orai1 channel function

scientific article published on 26 January 2016

Co-localization of CD3 and prion protein in Jurkat lymphocytes after hypothermal stimulation

artículo científico publicado en 2004

Communication between N-terminus and Loop2 tunes Orai activation.

artículo científico publicado en 2017

Complex role of STIM1 in the activation of store-independent Orai1/3 channels.

artículo científico publicado en 2014

Cooperativeness of Orai cytosolic domains tunes subtype-specific gating.

artículo científico publicado en 2011

Crosstalk between voltage-independent Ca2+ channels and L-type Ca2+ channels in A7r5 vascular smooth muscle cells at elevated intracellular pH: evidence for functional coupling between L-type Ca2+ channels and a 2-APB-sensitive cation channel.

artículo científico publicado en 2003

Cytosolic Ca2+ prevents the subplasmalemmal clustering of STIM1: an intrinsic mechanism to avoid Ca2+ overload

artículo científico publicado en 2008

Detailed Evidence for an Unparalleled Interaction Mode between Calmodulin and Orai Proteins

artículo científico publicado en 2017

Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+-dependent inactivation.

artículo científico publicado en 2006

Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.

artículo científico publicado en 2008

Essential role of the beta subunit in modulation of C-class L-type Ca2+ channels by intracellular pH.

artículo científico publicado en 1997

Expression of Trp3 determines sensitivity of capacitative Ca2+ entry to nitric oxide and mitochondrial Ca2+ handling: evidence for a role of Trp3 as a subunit of capacitative Ca2+ entry channels.

artículo científico publicado en 2001

Extending Optogenetics to a Ca2+-Selective Channel ⬇️

artículo científico publicado el 29 de julio de 2011

Gating and permeation of Orai channels.

artículo científico publicado en 2012

Guanylate cyclase activation by organic nitrates is not mediated via nitrite

artículo científico publicado en 1988

Identification of a rare subset of adipose tissue-resident progenitor cells, which express CD133 and TRPC3 as a VEGF-regulated Ca2+ entry channel.

artículo científico publicado en 2008

In this issue of Channels: Special issue on STIM and Orai

artículo científico publicado en 2013

Inactivation-mimicking block of the epithelial calcium channel TRPV6

artículo científico publicado en 2020

Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant

scientific article published on 14 April 2009

Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle.

artículo científico publicado en 2013

Inhibition of a store-operated Ca2+ entry pathway in human endothelial cells by the isoquinoline derivative LOE 908.

artículo científico publicado en 1996

Interhelical interactions within the STIM1 CC1 domain modulate CRAC channel activation

artículo científico publicado en 2020

Lipid-independent control of endothelial and neuronal TRPC3 channels by light

artículo científico publicado en 2019

Live-cell imaging of ER-PM contact architecture by a novel TIRFM approach reveals extension of junctions in response to store-operated Ca(2+)-entry

artículo científico publicado en 2016

Lpe10p modulates the activity of the Mrs2p-based yeast mitochondrial Mg2+ channel.

artículo científico publicado en 2010

Membrane binding of beta2-glycoprotein I can be described by a two-state reaction model: an atomic force microscopy and surface plasmon resonance study

artículo científico publicado en 2005

Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation

artículo científico publicado en 2015

Modulation of the smooth-muscle L-type Ca2+ channel alpha1 subunit (alpha1C-b) by the beta2a subunit: a peptide which inhibits binding of beta to the I-II linker of alpha1 induces functional uncoupling

artículo científico publicado en 2000

Modulation of voltage- and Ca2+-dependent gating of CaV1.3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain.

artículo científico publicado en 2008

Molecular Determinants within N Terminus of Orai3 Protein That Control Channel Activation and Gating ⬇️

artículo científico publicado el 9 de septiembre de 2011

Molecular determinant for run-down of L-type Ca2+ channels localized in the carboxyl terminus of the 1C subunit

artículo científico publicado en 2000

Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant

artículo científico publicado en 2009

Molecular mechanisms of STIM/Orai communication.

artículo científico publicado en 2016

Mrs2p forms a high conductance Mg2+ selective channel in mitochondria.

artículo científico publicado en 2007

Nanopatterned polymer substrates promote endothelial proliferation by initiation of β-catenin transcriptional signaling

artículo científico publicado en 2012

Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca(2+) entry pathways

artículo científico publicado en 2012

Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells. ⬇️

artículo científico publicado en 2010

Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex.

artículo científico publicado en 2006

Plasticity in Ca2+ selectivity of Orai1/Orai3 heteromeric channel.

artículo científico publicado en 2009

Potent block of Cl- channels by antiallergic drugs

artículo científico publicado en 1992

Proliferation of aligned mammalian cells on laser-nanostructured polystyrene.

artículo científico publicado en 2008

Rapid NMR-scale purification of 15N,13C isotope-labeled recombinant human STIM1 coiled coil fragments.

artículo científico publicado en 2018

Recent progress on STIM1 domains controlling Orai activation.

artículo científico publicado en 2009

Removing non-random artifacts from patch clamp traces

artículo científico publicado en 1998

Resting state Orai1 diffuses as homotetramer in the plasma membrane of live mammalian cells

artículo científico publicado en 2010

S-nitrosation controls gating and conductance of the alpha 1 subunit of class C L-type Ca(2+) channels.

artículo científico publicado en 2001

STIM1 activation of Orai1

scientific article published on 30 November 2018

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

artículo científico publicado en 2013

Sequential activation of STIM1 links Ca2+ with luminal domain unfolding

artículo científico publicado en 2019

Store depletion-activated CaT1 currents in rat basophilic leukemia mast cells are inhibited by 2-aminoethoxydiphenyl borate. Evidence for a regulatory component that controls activation of both CaT1 and CRAC (Ca(2+) release-activated Ca(2+) channel)

artículo científico publicado en 2002

Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia

artículo científico publicado en 2013

Structure, regulation and biophysics of I(CRAC), STIM/Orai1.

artículo científico

TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells.

artículo científico publicado en 2006

TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival

artículo científico publicado en 2014

The STIM-Orai Pathway: The Interactions Between STIM and Orai.

artículo científico publicado en 2017

The STIM/Orai coupling machinery.

artículo científico publicado en 2008

The STIM1/Orai signaling machinery

artículo científico publicado en 2013

The STIM1: Orai Interaction

artículo científico publicado en 2016

The action of selective CRAC channel blockers is affected by the Orai pore geometry ⬇️

artículo científico publicado el 5 de diciembre de 2012

The benzazepine/benzothiazepine binding domain of the cardiac L-type Ca2+ channel is accessible only from the extracellular side

artículo científico publicado en 1993

The dihydropyridine niguldipine inhibits T-type Ca2+ currents in atrial myocytes

artículo científico publicado en 1992

The extended transmembrane Orai1 N-terminal (ETON) region combines binding interface and gate for Orai1 activation by STIM1.

artículo científico publicado en 2013

The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.

artículo científico publicado en 2007

Tolerance to nitroglycerin is caused by reduced guanylate cyclase activation

artículo científico publicado en 1989

Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.

artículo científico publicado en 2017

Trp proteins form store-operated cation channels in human vascular endothelial cells

artículo científico publicado en 1998

Trypsin increases availability and open probability of cardiac L-type Ca2+ channels without affecting inactivation induced by Ca2+.

artículo científico publicado en 1995

UV surface modification of a new nanocomposite polymer to improve cytocompatibility

artículo científico publicado en 2007

Lista de obras de Christoph Romanin

2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size.

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription

A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).

A dual mechanism promotes switching of the Stormorken STIM1 R304W mutant into the activated state.

A novel homology model of TRPC3 reveals allosteric coupling between gate and selectivity filter.

A sequence in the carboxy-terminus of the alpha(1C) subunit important for targeting, conductance and open probability of L-type Ca(2+) channels.

A type 2A phosphatase-sensitive phosphorylation site controls modal gating of L-type Ca2+ channels in human vascular smooth-muscle cells.

ATP-induced activation of expressed RyR3 at low free calcium.

Action of calpastatin in prevention of cardiac L-type Ca2+ channel run-down cannot be mimicked by synthetic calpain inhibitors

Activity of cardiac L-type Ca2+ channels is sensitive to cytoplasmic calcium

Adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene.

Adhesion and proliferation of human vascular cells on UV-light-modified polymers

An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel

Assembly domains in TRP channels.

Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N-terminus.

Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry

Basal dephosphorylation controls slow gating of L-type Ca2+ channels in human vascular smooth muscle.

C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels

CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions

CRAC inhibitors: identification and potential

Ca(2+) release-activated Ca(2+) (CRAC) current, structure, and function.

Ca(2+) sensors of L-type Ca(2+) channel

Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger.

CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells.

Calpastatin and nucleotides stabilize cardiac calcium channel activity in excised patches

Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.

Cell adhesion on polytetrafluoroethylene modified by UV-irradiation in an ammonia atmosphere.

Cell microarrays on photochemically modified polytetrafluoroethylene

Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction

Cellular cholesterol controls TRPC3 function: evidence from a novel dominant-negative knockdown strategy.

Cholesterol modulates Orai1 channel function

Co-localization of CD3 and prion protein in Jurkat lymphocytes after hypothermal stimulation

Communication between N-terminus and Loop2 tunes Orai activation.

Complex role of STIM1 in the activation of store-independent Orai1/3 channels.

Cooperativeness of Orai cytosolic domains tunes subtype-specific gating.

Crosstalk between voltage-independent Ca2+ channels and L-type Ca2+ channels in A7r5 vascular smooth muscle cells at elevated intracellular pH: evidence for functional coupling between L-type Ca2+ channels and a 2-APB-sensitive cation channel.

Cytosolic Ca2+ prevents the subplasmalemmal clustering of STIM1: an intrinsic mechanism to avoid Ca2+ overload

Detailed Evidence for an Unparalleled Interaction Mode between Calmodulin and Orai Proteins

Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+-dependent inactivation.

Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.

Essential role of the beta subunit in modulation of C-class L-type Ca2+ channels by intracellular pH.

Expression of Trp3 determines sensitivity of capacitative Ca2+ entry to nitric oxide and mitochondrial Ca2+ handling: evidence for a role of Trp3 as a subunit of capacitative Ca2+ entry channels.

Extending Optogenetics to a Ca2+-Selective Channel ⬇️

Gating and permeation of Orai channels.

Guanylate cyclase activation by organic nitrates is not mediated via nitrite

Identification of a rare subset of adipose tissue-resident progenitor cells, which express CD133 and TRPC3 as a VEGF-regulated Ca2+ entry channel.

In this issue of Channels: Special issue on STIM and Orai

Inactivation-mimicking block of the epithelial calcium channel TRPV6

Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant

Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle.

Inhibition of a store-operated Ca2+ entry pathway in human endothelial cells by the isoquinoline derivative LOE 908.

Interhelical interactions within the STIM1 CC1 domain modulate CRAC channel activation

Lipid-independent control of endothelial and neuronal TRPC3 channels by light

Live-cell imaging of ER-PM contact architecture by a novel TIRFM approach reveals extension of junctions in response to store-operated Ca(2+)-entry

Lpe10p modulates the activity of the Mrs2p-based yeast mitochondrial Mg2+ channel.

Membrane binding of beta2-glycoprotein I can be described by a two-state reaction model: an atomic force microscopy and surface plasmon resonance study

Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation

Modulation of the smooth-muscle L-type Ca2+ channel alpha1 subunit (alpha1C-b) by the beta2a subunit: a peptide which inhibits binding of beta to the I-II linker of alpha1 induces functional uncoupling

Modulation of voltage- and Ca2+-dependent gating of CaV1.3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain.

Molecular Determinants within N Terminus of Orai3 Protein That Control Channel Activation and Gating ⬇️

Molecular determinant for run-down of L-type Ca2+ channels localized in the carboxyl terminus of the 1C subunit

Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant

Molecular mechanisms of STIM/Orai communication.

Mrs2p forms a high conductance Mg2+ selective channel in mitochondria.

Nanopatterned polymer substrates promote endothelial proliferation by initiation of β-catenin transcriptional signaling

Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca(2+) entry pathways

Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells. ⬇️

Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex.

Plasticity in Ca2+ selectivity of Orai1/Orai3 heteromeric channel.

Potent block of Cl- channels by antiallergic drugs

Proliferation of aligned mammalian cells on laser-nanostructured polystyrene.

Rapid NMR-scale purification of 15N,13C isotope-labeled recombinant human STIM1 coiled coil fragments.

Recent progress on STIM1 domains controlling Orai activation.

Removing non-random artifacts from patch clamp traces

Resting state Orai1 diffuses as homotetramer in the plasma membrane of live mammalian cells

S-nitrosation controls gating and conductance of the alpha 1 subunit of class C L-type Ca(2+) channels.

STIM1 activation of Orai1

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry