Lista de obras - Beatriz de Pascual-Teresa

Adrenomedullin: a new and promising target for drug discovery

artículo científico publicado en 2006

Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities

artículo científico publicado en 2005

An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily.

artículo científico publicado en 2014

Assessment of Solvation Effects on Calculated Binding Affinity Differences: Trypsin Inhibition by Flavonoids as a Model System for Congeneric Series

article

Azino-Fused Benzimidazolium Salts as DNA Intercalating Agents. 2

Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis

artículo científico publicado en 1993

Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family

artículo científico publicado en 2015

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders

artículo científico publicado en 2017

Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells. A study on the mode of action

artículo científico publicado en 2014

Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold

artículo científico publicado en 2018

From a MMP2/CK2 multitarget approach to the identification of potent and selective MMP13 inhibitors

scientific article published on 01 January 2019

Human protein kinase CK2 phosphorylates matrix metalloproteinase 2 and inhibits its activity

artículo científico publicado en 2014

Identification of first proadrenomedullin N-terminal 20 peptide (PAMP) modulator by means of virtual screening and NMR interaction experiments

artículo científico publicado en 2012

In silico identification and in vivo characterization of small molecule therapeutic hypothermia mimetics.

artículo científico publicado en 2017

Intercalators as anticancer drugs.

artículo científico publicado en 2001

MMP-2 selectivity in hydroxamate-type inhibitors.

artículo científico publicado en 2012

Molecular dynamics simulations of the bis-intercalated complexes of ditercalinium and Flexi-Di with the hexanucleotide d(GCGCGC)2: theoretical analysis of the interaction and rationale for the sequence binding specificity.

artículo científico publicado en 1996

Multisite-directed inhibitors of protein kinase CK2: new challenges.

artículo científico publicado en 2011

Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 inhibitors

artículo científico publicado en 2020

New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.

artículo científico publicado en 2004

New clicked full agonists of the estrogen receptor β

scholarly article in RSC Advances, vol. 3 no. 11, 2013

New scaffolds for the design of selective estrogen receptor modulators

artículo científico publicado en 2008

Novel DNA Intercalators Based on the Pyridazino[1‘,6‘:1,2]pyrido[4,3-b]indol-5-inium System

Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol.

artículo científico publicado en 2018

Potent “Clicked” MMP2 Inhibitors: Synthesis, Molecular Modeling and Biological Exploration

scientific article published on 06 May 2011

Progress towards water-soluble triazole-based selective MMP-2 inhibitors.

artículo científico publicado en 2013

Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases

artículo científico publicado en 2005

Small-molecule negative modulators of adrenomedullin: design, synthesis, and 3D-QSAR study

artículo científico publicado en 2008

Structure of micelle-bound adrenomedullin: a first step toward the analysis of its interactions with receptors and small molecules

artículo científico publicado en 2012

Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins.

artículo científico publicado en 2011

Synthesis and DNA Binding Properties of γ-Carbolinium Derivatives and Benzologues

Synthesis and biological evaluation of analogues of butyrolactone I and molecular model of its interaction with CDK2.

artículo científico publicado en 2004

Synthesis and cytotoxicity of hydrophobic esters of podophyllotoxins

artículo científico publicado en 2004

Synthesis, antitumor activity, molecular modeling, and DNA binding properties of a new series of imidazonaphthalimides.

artículo científico publicado en 2002

Synthesis, biological evaluation, and three-dimensional quantitative structure-activity relationship study of small-molecule positive modulators of adrenomedullin

artículo científico publicado en 2005

Synthesis, cytotoxic activities and proposed mode of binding of a series of bis([(9-oxo-9,10-dihydroacridine-4-carbonyl)amino]alkyl) alkylamines

artículo científico publicado en 2002

Targeting matrix metalloproteinases: exploring the dynamics of the s1' pocket in the design of selective, small molecule inhibitors

artículo científico publicado en 2014

alpha-Alkyl-alpha-Amino-beta-Lactam Peptides: Design, Synthesis, and Conformational Features.

artículo científico publicado en 1999

Lista de obras de Beatriz de Pascual-Teresa

Adrenomedullin: a new and promising target for drug discovery

Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities

An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily.

Assessment of Solvation Effects on Calculated Binding Affinity Differences: Trypsin Inhibition by Flavonoids as a Model System for Congeneric Series

Azino-Fused Benzimidazolium Salts as DNA Intercalating Agents. 2

Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis

Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders

Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells. A study on the mode of action

Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold

From a MMP2/CK2 multitarget approach to the identification of potent and selective MMP13 inhibitors

Human protein kinase CK2 phosphorylates matrix metalloproteinase 2 and inhibits its activity

Identification of first proadrenomedullin N-terminal 20 peptide (PAMP) modulator by means of virtual screening and NMR interaction experiments

In silico identification and in vivo characterization of small molecule therapeutic hypothermia mimetics.

Intercalators as anticancer drugs.

MMP-2 selectivity in hydroxamate-type inhibitors.

Molecular dynamics simulations of the bis-intercalated complexes of ditercalinium and Flexi-Di with the hexanucleotide d(GCGCGC)2: theoretical analysis of the interaction and rationale for the sequence binding specificity.

Multisite-directed inhibitors of protein kinase CK2: new challenges.

Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 inhibitors

New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.

New clicked full agonists of the estrogen receptor β

New scaffolds for the design of selective estrogen receptor modulators

Novel DNA Intercalators Based on the Pyridazino[1‘,6‘:1,2]pyrido[4,3-b]indol-5-inium System

Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol.

Potent “Clicked” MMP2 Inhibitors: Synthesis, Molecular Modeling and Biological Exploration

Progress towards water-soluble triazole-based selective MMP-2 inhibitors.

Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases

Small-molecule negative modulators of adrenomedullin: design, synthesis, and 3D-QSAR study

Structure of micelle-bound adrenomedullin: a first step toward the analysis of its interactions with receptors and small molecules

Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins.

Synthesis and DNA Binding Properties of γ-Carbolinium Derivatives and Benzologues

Synthesis and biological evaluation of analogues of butyrolactone I and molecular model of its interaction with CDK2.

Synthesis and cytotoxicity of hydrophobic esters of podophyllotoxins

Synthesis, antitumor activity, molecular modeling, and DNA binding properties of a new series of imidazonaphthalimides.

Synthesis, biological evaluation, and three-dimensional quantitative structure-activity relationship study of small-molecule positive modulators of adrenomedullin

Synthesis, cytotoxic activities and proposed mode of binding of a series of bis([(9-oxo-9,10-dihydroacridine-4-carbonyl)amino]alkyl) alkylamines

Targeting matrix metalloproteinases: exploring the dynamics of the s1' pocket in the design of selective, small molecule inhibitors

alpha-Alkyl-alpha-Amino-beta-Lactam Peptides: Design, Synthesis, and Conformational Features.