Lista de obras - Ana Ramos - Dominio Público Uruguay

A Novel Photochemical Vinylcyclopropane Rearrangement Yielding 6,7-Dihydro-5H-benzocycloheptene Derivatives

artículo científico publicado en 2000

A Study of the Competition between the Di-.pi.-methane and the Azadi-.pi.-methane Processes in 2-Vinyl-.beta.,.gamma.-unsaturated Oxime Derivatives. The Novel Azadi-.pi.-methane Reactivity of .beta.,.gamma.-Unsaturated Oximes

article

A novel photochemical ring contraction of 4H-pyrans. A new route to selectively substituted cyclobutenes

article

A study on the scope of the photochemical 1,3-migration of oximino groups in β,γ-unsaturated oximes and oxime derivatives

article

A study on the scope of the photochemical ring contraction of substituted 2-amino-3-cyano-4H-pyrans to cyclobutenes: crystal structure of 3-carbamoyl-3-cyano-1-ethoxycarbonyl-4-isopropyl-2-phenylcyclobutene

Adrenomedullin: a new and promising target for drug discovery

artículo científico publicado en 2006

Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities

artículo científico publicado en 2005

An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily.

artículo científico publicado en 2014

Bis[5,5-bis(4-methoxyphenyl)-3,3-dimethyl-2-tetrahydrofuranyl] Ether

Chromophore-modified bisnaphthalimides: DNA recognition, topoisomerase inhibition, and cytotoxic properties of two mono- and bisfuronaphthalimides

artículo científico publicado en 2003

Design and synthesis of novel dual-target agents for HDAC1 and CK2 inhibition

scholarly article in RSC Advances, vol. 6 no. 71, 2016

Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family

artículo científico publicado en 2015

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders

artículo científico publicado en 2017

Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells. A study on the mode of action

artículo científico publicado en 2014

Extension of the aza-di-π-methane reaction to stable derivatives. Photochemical cyclization of β,γ-unsaturated oxime acetates

article

From a MMP2/CK2 multitarget approach to the identification of potent and selective MMP13 inhibitors

scientific article published on 01 January 2019

Human protein kinase CK2 phosphorylates matrix metalloproteinase 2 and inhibits its activity

artículo científico publicado en 2014

Identification of first proadrenomedullin N-terminal 20 peptide (PAMP) modulator by means of virtual screening and NMR interaction experiments

artículo científico publicado en 2012

In silico identification and in vivo characterization of small molecule therapeutic hypothermia mimetics.

artículo científico publicado en 2017

Intercalators as anticancer drugs.

artículo científico publicado en 2001

MMP-2 selectivity in hydroxamate-type inhibitors.

artículo científico publicado en 2012

Multisite-directed inhibitors of protein kinase CK2: new challenges.

artículo científico publicado en 2011

Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 inhibitors

artículo científico publicado en 2020

Naphthalimides as anti-cancer agents: synthesis and biological activity

artículo científico publicado en 2001

New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.

artículo científico publicado en 2004

New clicked full agonists of the estrogen receptor β

scholarly article in RSC Advances, vol. 3 no. 11, 2013

New clicked thiirane derivatives as gelatinase inhibitors: the relevance of the P1′ segment

scholarly article in RSC Advances, vol. 4 no. 34, 2014

New scaffolds for the design of selective estrogen receptor modulators

artículo científico publicado en 2008

Novel photochemical behaviour of the oximes and hydrazones of β,γ-unsaturated carbonyl compounds

Photochemical reactivity of imines from benzil mono-oxime esters

article

Photochemical synthesis of oxime acetates derivatives of 1-carbaldehydobicyclo[n.1.0]alkanes by the aza-di-π-methane rearrangement

Potent “Clicked” MMP2 Inhibitors: Synthesis, Molecular Modeling and Biological Exploration

scientific article published on 06 May 2011

Progress towards water-soluble triazole-based selective MMP-2 inhibitors.

artículo científico publicado en 2013

Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases

artículo científico publicado en 2005

Retro-ene reactions of N-substituted derivatives of 4-aza-2,2-dimethyl-1-phenyl-3-butenone and related compounds

Small-molecule negative modulators of adrenomedullin: design, synthesis, and 3D-QSAR study

artículo científico publicado en 2008

Structure of micelle-bound adrenomedullin: a first step toward the analysis of its interactions with receptors and small molecules

artículo científico publicado en 2012

Synthesis and biological evaluation of analogues of butyrolactone I and molecular model of its interaction with CDK2.

artículo científico publicado en 2004

Synthesis of cyclobutenes by the novel photochemical ring contraction of 4-substituted 2-amino-3,5-dicyano-6-phenyl-4H-pyrans

Synthesis, antitumor activity, molecular modeling, and DNA binding properties of a new series of imidazonaphthalimides.

artículo científico publicado en 2002

Synthesis, biological activity and structural study of new benzotriazole-based protein kinase CK2 inhibitors

scholarly article in RSC Advances, vol. 5 no. 89, 2015

Synthesis, biological evaluation and DNA binding properties of novel mono and bisnaphthalimides.

artículo científico publicado en 2003

Synthesis, biological evaluation, and three-dimensional quantitative structure-activity relationship study of small-molecule positive modulators of adrenomedullin

artículo científico publicado en 2005

Targeting matrix metalloproteinases: exploring the dynamics of the s1' pocket in the design of selective, small molecule inhibitors

artículo científico publicado en 2014

The aza-di-π-methane rearrangement of β-γ-unsaturated oximes

Towards β-selectivity in functional estrogen receptor antagonists

artículo científico publicado en 2012

Lista de obras de Ana Ramos

A Novel Photochemical Vinylcyclopropane Rearrangement Yielding 6,7-Dihydro-5H-benzocycloheptene Derivatives

A Study of the Competition between the Di-.pi.-methane and the Azadi-.pi.-methane Processes in 2-Vinyl-.beta.,.gamma.-unsaturated Oxime Derivatives. The Novel Azadi-.pi.-methane Reactivity of .beta.,.gamma.-Unsaturated Oximes

A novel photochemical ring contraction of 4H-pyrans. A new route to selectively substituted cyclobutenes

A study on the scope of the photochemical 1,3-migration of oximino groups in β,γ-unsaturated oximes and oxime derivatives

A study on the scope of the photochemical ring contraction of substituted 2-amino-3-cyano-4H-pyrans to cyclobutenes: crystal structure of 3-carbamoyl-3-cyano-1-ethoxycarbonyl-4-isopropyl-2-phenylcyclobutene

Adrenomedullin: a new and promising target for drug discovery

Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities

An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily.

Bis[5,5-bis(4-methoxyphenyl)-3,3-dimethyl-2-tetrahydrofuranyl] Ether

Chromophore-modified bisnaphthalimides: DNA recognition, topoisomerase inhibition, and cytotoxic properties of two mono- and bisfuronaphthalimides

Design and synthesis of novel dual-target agents for HDAC1 and CK2 inhibition

Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders

Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells. A study on the mode of action

Extension of the aza-di-π-methane reaction to stable derivatives. Photochemical cyclization of β,γ-unsaturated oxime acetates

From a MMP2/CK2 multitarget approach to the identification of potent and selective MMP13 inhibitors

Human protein kinase CK2 phosphorylates matrix metalloproteinase 2 and inhibits its activity

Identification of first proadrenomedullin N-terminal 20 peptide (PAMP) modulator by means of virtual screening and NMR interaction experiments

In silico identification and in vivo characterization of small molecule therapeutic hypothermia mimetics.

Intercalators as anticancer drugs.

MMP-2 selectivity in hydroxamate-type inhibitors.

Multisite-directed inhibitors of protein kinase CK2: new challenges.

Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 inhibitors

Naphthalimides as anti-cancer agents: synthesis and biological activity

New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.

New clicked full agonists of the estrogen receptor β

New clicked thiirane derivatives as gelatinase inhibitors: the relevance of the P1′ segment

New scaffolds for the design of selective estrogen receptor modulators

Novel photochemical behaviour of the oximes and hydrazones of β,γ-unsaturated carbonyl compounds

Photochemical reactivity of imines from benzil mono-oxime esters

Photochemical synthesis of oxime acetates derivatives of 1-carbaldehydobicyclo[n.1.0]alkanes by the aza-di-π-methane rearrangement

Potent “Clicked” MMP2 Inhibitors: Synthesis, Molecular Modeling and Biological Exploration

Progress towards water-soluble triazole-based selective MMP-2 inhibitors.

Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases

Retro-ene reactions of N-substituted derivatives of 4-aza-2,2-dimethyl-1-phenyl-3-butenone and related compounds

Small-molecule negative modulators of adrenomedullin: design, synthesis, and 3D-QSAR study

Structure of micelle-bound adrenomedullin: a first step toward the analysis of its interactions with receptors and small molecules

Synthesis and biological evaluation of analogues of butyrolactone I and molecular model of its interaction with CDK2.

Synthesis of cyclobutenes by the novel photochemical ring contraction of 4-substituted 2-amino-3,5-dicyano-6-phenyl-4H-pyrans

Synthesis, antitumor activity, molecular modeling, and DNA binding properties of a new series of imidazonaphthalimides.

Synthesis, biological activity and structural study of new benzotriazole-based protein kinase CK2 inhibitors

Synthesis, biological evaluation and DNA binding properties of novel mono and bisnaphthalimides.

Synthesis, biological evaluation, and three-dimensional quantitative structure-activity relationship study of small-molecule positive modulators of adrenomedullin

Targeting matrix metalloproteinases: exploring the dynamics of the s1' pocket in the design of selective, small molecule inhibitors

The aza-di-π-methane rearrangement of β-γ-unsaturated oximes

Towards β-selectivity in functional estrogen receptor antagonists

Unexpected Oxadi-π-methane Rearrangement of β,γ-Unsaturated Aldehydes

Unexpected reactivity of the anion derived from benzophenone benzoylhydrazone in the presence of electrophiles