Lista de obras - John F Thompson - Dominio Público Uruguay

A comparison of single molecule and amplification based sequencing of cancer transcriptomes

artículo científico publicado en 2011

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

artículo científico publicado en 2014

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

artículo científico publicado en 2011

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

artículo científico publicado en 2009

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

artículo científico publicado en 2009

An association study of 43 SNPs in 16 candidate genes with atorvastatin response

artículo científico publicado en 2005

Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels

artículo científico publicado en 2004

Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels

artículo científico publicado en 2004

Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes

article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

artículo científico publicado en 2007

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease.

artículo científico publicado en 2005

Cellular factors couple recombination with growth phase: characterization of a new component in the lambda site-specific recombination pathway.

artículo científico publicado en 1987

Cholesterol 7 alpha hydroxylase promoter separated from cyclophilin pseudogene by Alu sequence

artículo científico publicado en 1993

Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib.

artículo científico publicado en 2005

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

artículo científico publicado en 2016

Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort

artículo científico publicado en 2009

Control of directionality in lambda site specific recombination

artículo científico publicado en 1985

Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis

artículo científico publicado en 2000

Dependence of 4'-(hydroxymethyl)-4,5',8-trimethylpsoralen photoaddition on the conformation of RNA

artículo científico publicado en 1982

Determination of the secondary structure of Drosophila melanogaster 5 S RNA by hydroxymethyltrimethylpsoralen crosslinking.

artículo científico publicado en 1981

Direct biomechanical induction of endogenous calcineurin inhibitor Down Syndrome Critical Region-1 in cardiac myocytes

scientific journal article

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

artículo científico publicado en 2013

E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo

artículo científico publicado en 1990

Empirical estimation of protein-induced DNA bending angles: applications to lambda site-specific recombination complexes

artículo científico publicado en 1988

Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences

scientific article published on 28 May 2008

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

artículo científico publicado en 2011

Frequency and function of CETP variants among individuals of Asian ancestry

artículo científico publicado en 2008

Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array

artículo científico publicado en 2010

Genetic association of the CCR5 region with lipid levels in at-risk cardiovascular patients.

artículo científico

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

artículo científico publicado en 2010

Genetically determined height and coronary artery disease

artículo científico publicado en 2015

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

artículo científico publicado en 2009

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

artículo científico publicado en 2010

Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease

artículo científico publicado en 2009

Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides

artículo científico publicado en 2008

Genomewide association analysis of coronary artery disease

artículo científico publicado en 2007

Helicos single-molecule sequencing of bacterial genomes

artículo científico publicado en 2011

High-density genotyping and functional SNP localization in the CETP gene

artículo científico publicado en 2006

Highly polymorphic repeat region in the CETP promoter induces unusual DNA structure

artículo científico publicado en 2004

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

artículo científico publicado en 2011

Identification of IEX-1 as a biomechanically controlled nuclear factor-kappaB target gene that inhibits cardiomyocyte hypertrophy

artículo científico publicado en 2002

Identification of a site of psoralen crosslinking in E. coli 16S ribosomal RNA

artículo científico publicado en 1982

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification of seven loci affecting mean telomere length and their association with disease

artículo científico publicado en 2013

Identification of the modified nucleotides produced by covalent photoaddition of hydroxymethyltrimethylpsoralen to RNA.

artículo científico publicado en 1981

Improving ancient DNA read mapping against modern reference genomes

artículo científico publicado en 2012

Improving the performance of true single molecule sequencing for ancient DNA

artículo científico publicado en 2012

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

artículo científico publicado en 2012

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

artículo científico publicado en 2010

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

artículo científico publicado en 2011

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

artículo científico publicado en 2017

Mapping and sequencing DNA using nanopores and nanodetectors.

artículo científico publicado en 2012

Mechanical strain induces specific changes in the synthesis and organization of proteoglycans by vascular smooth muscle cells

artículo científico publicado en 2001

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

artículo científico publicado en 2010

Mutation of a Protease-sensitive Region in Firefly Luciferase Alters Light Emission Properties ⬇️

artículo científico publicado el 25 de julio de 1997

Mutations in an integration host factor-binding site: effect on lambda site-specific recombination and regulatory implications

artículo científico publicado en 1986

Native molecular state of adeno-associated viral vectors revealed by single-molecule sequencing

artículo científico publicado en 2011

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

artículo científico publicado en 2009

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

Novel lactone compounds from Mortierella verticillata that induce the human low density lipoprotein receptor gene: fermentation, isolation, structural elucidation and biological activities

article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Novel variants in human and monkey CETP.

artículo científico publicado en 2005

Orthogonal NGS for High Throughput Clinical Diagnostics

artículo científico publicado en 2016

Overexpression of eotaxin and the CCR3 receptor in human atherosclerosis: using genomic technology to identify a potential novel pathway of vascular inflammation

artículo científico publicado en 2000

Pharmacogenomics: integration into drug discovery and development.

artículo científico publicado en 2005

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

artículo científico publicado en 2012

Polymorphisms in the CETP gene and association with CETP mass and HDL levels

artículo científico publicado en 2003

Protein binding to the low density lipoprotein receptor promoter in vivo is differentially affected by gene activation in primary human cells

article

Protein fusions of BPI with CETP retain functions inherent to each

scientific article published on 01 October 2006

Protein-protein interactions in a higher-order structure direct lambda site-specific recombination

scientific article published on 01 June 1987

Protocol dependence of sequencing-based gene expression measurements

artículo científico publicado en 2011

Quantification of the yeast transcriptome by single-molecule sequencing

artículo científico publicado en 2009

Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

artículo científico publicado en 2013

Recurrent heteroplasmy for the MT-ATP6 p.Ser148Asn (m.8969G>A) mutation in patients with syndromic congenital sideroblastic anemia of variable clinical severity

scientific article published on 13 July 2018

Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1.

artículo científico publicado en 2009

Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease

scientific article published on 24 March 2008

Role of a KCNH2 polymorphism (R1047 L) in dofetilide-induced Torsades de Pointes

artículo científico publicado en 2004

Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms

artículo científico publicado en 2009

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

artículo científico publicado en 2010

Sequencing of the cholesteryl ester transfer protein 5' regulatory region using artificial transposons

artículo científico publicado en 1997

Single molecule sequencing with a HeliScope genetic analysis system

artículo científico publicado en 2010

Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer.

artículo científico publicado en 2015

Single-molecule sequencing: sequence methods to enable accurate quantitation.

artículo científico

Single-step capture and sequencing of natural DNA for detection of BRCA1 mutations

artículo científico publicado en 2011

Structure of E. coli 16S RNA elucidated by psoralen crosslinking

scientific article published on 01 April 1983

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

artículo científico publicado en 2017

The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA

artículo científico publicado en 2010

The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA.

artículo científico publicado en 2011

The properties and applications of single-molecule DNA sequencing.

artículo científico publicado en 2011

Transcriptional Modulators Affect in Vivo Protein Binding to the Low Density Lipoprotein Receptor and 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Promoters

scientific article published in Journal of Biological Chemistry

Transcriptional Profile of Mechanically Induced Genes in Human Vascular Smooth Muscle Cells

article

True single-molecule DNA sequencing of a pleistocene horse bone

artículo científico publicado en 2011

Truncation of human squalene synthase yields active, crystallizable protein

artículo científico publicado en 1998

Urotensin-II system in genetic control of blood pressure and renal function

artículo científico publicado en 2013

Virtual terminator nucleotides for next-generation DNA sequencing.

artículo científico publicado en 2009

What would you do if you could sequence everything?

artículo científico publicado en 2008

Lista de obras de John F Thompson

A comparison of single molecule and amplification based sequencing of cancer transcriptomes

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

An association study of 43 SNPs in 16 candidate genes with atorvastatin response

Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels

Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels

Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Biological, clinical and population relevance of 95 loci for blood lipids

CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease.

Cellular factors couple recombination with growth phase: characterization of a new component in the lambda site-specific recombination pathway.

Cholesterol 7 alpha hydroxylase promoter separated from cyclophilin pseudogene by Alu sequence

Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib.

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort

Control of directionality in lambda site specific recombination

Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis

Dependence of 4'-(hydroxymethyl)-4,5',8-trimethylpsoralen photoaddition on the conformation of RNA

Determination of the secondary structure of Drosophila melanogaster 5 S RNA by hydroxymethyltrimethylpsoralen crosslinking.

Direct biomechanical induction of endogenous calcineurin inhibitor Down Syndrome Critical Region-1 in cardiac myocytes

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo

Empirical estimation of protein-induced DNA bending angles: applications to lambda site-specific recombination complexes

Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

Frequency and function of CETP variants among individuals of Asian ancestry

Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array

Genetic association of the CCR5 region with lipid levels in at-risk cardiovascular patients.

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

Genetically determined height and coronary artery disease

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease

Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides

Genomewide association analysis of coronary artery disease

Helicos single-molecule sequencing of bacterial genomes

High-density genotyping and functional SNP localization in the CETP gene

Highly polymorphic repeat region in the CETP promoter induces unusual DNA structure

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

Identification of IEX-1 as a biomechanically controlled nuclear factor-kappaB target gene that inhibits cardiomyocyte hypertrophy

Identification of a site of psoralen crosslinking in E. coli 16S ribosomal RNA

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Identification of seven loci affecting mean telomere length and their association with disease

Identification of the modified nucleotides produced by covalent photoaddition of hydroxymethyltrimethylpsoralen to RNA.

Improving ancient DNA read mapping against modern reference genomes

Improving the performance of true single molecule sequencing for ancient DNA

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Large-scale association analysis identifies new risk loci for coronary artery disease

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

Mapping and sequencing DNA using nanopores and nanodetectors.

Mechanical strain induces specific changes in the synthesis and organization of proteoglycans by vascular smooth muscle cells

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Mutation of a Protease-sensitive Region in Firefly Luciferase Alters Light Emission Properties ⬇️

Mutations in an integration host factor-binding site: effect on lambda site-specific recombination and regulatory implications

Native molecular state of adeno-associated viral vectors revealed by single-molecule sequencing

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

Novel lactone compounds from Mortierella verticillata that induce the human low density lipoprotein receptor gene: fermentation, isolation, structural elucidation and biological activities

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Novel variants in human and monkey CETP.

Orthogonal NGS for High Throughput Clinical Diagnostics

Overexpression of eotaxin and the CCR3 receptor in human atherosclerosis: using genomic technology to identify a potential novel pathway of vascular inflammation

Pharmacogenomics: integration into drug discovery and development.

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Polymorphisms in the CETP gene and association with CETP mass and HDL levels

Protein binding to the low density lipoprotein receptor promoter in vivo is differentially affected by gene activation in primary human cells

Protein fusions of BPI with CETP retain functions inherent to each

Protein-protein interactions in a higher-order structure direct lambda site-specific recombination

Protocol dependence of sequencing-based gene expression measurements

Quantification of the yeast transcriptome by single-molecule sequencing

Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

Recurrent heteroplasmy for the MT-ATP6 p.Ser148Asn (m.8969G>A) mutation in patients with syndromic congenital sideroblastic anemia of variable clinical severity

Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1.