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Lista de obras de Randall J Bateman

A LONGITUDINAL MORPHOMETRIC STUDY OF FAMILIAL ALZHEIMER’S DISEASE: RESULTS FROM DIAN

A LONGITUDINAL MORPHOMETRIC STUDY OF FAMILIAL ALZHEIMER’S DISEASE: RESULTS FROM DIAN

A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system

artículo científico publicado en 2009

A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials

artículo científico publicado en 2019

A novel PSEN1 (S230N) mutation causing early-onset Alzheimer's Disease associated with prosopagnosia, hoarding, and Parkinsonism.

artículo científico publicado en 2017

A novel cognitive disease progression model for clinical trials in autosomal-dominant Alzheimer's disease

artículo científico publicado en 2018

A randomized controlled study to evaluate the effect of bexarotene on amyloid-β and apolipoprotein E metabolism in healthy subjects

artículo científico publicado en 2016

A single dose of the γ-secretase inhibitor semagacestat alters the cerebrospinal fluid peptidome in humans

artículo científico publicado en 2016

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease

artículo científico publicado en 2020

A survey of attitudes toward clinical trials and genetic disclosure in autosomal dominant Alzheimer's disease

artículo científico publicado en 2015

A voxel-based morphometry study of volumetric MRI in familial Alzheimer's disease

Acute gamma-secretase inhibition of nonhuman primate CNS shifts amyloid precursor protein (APP) metabolism from amyloid-beta production to alternative APP fragments without amyloid-beta rebound

artículo científico publicado en 2010

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

artículo científico publicado en 2014

Age and amyloid effects on human central nervous system amyloid-beta kinetics

artículo científico publicado en 2015

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction

artículo científico publicado en 2011

Alzheimer's disease

artículo científico publicado en 2015

Alzheimer's disease and other dementias: advances in 2014.

artículo científico publicado en 2015

Alzheimer's disease therapeutic trials: EU/US task force report on recruitment, retention, and methodology ⬇️

artículo científico publicado el 1 de abril de 2012

Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease

scientific article published on 06 February 2020

Amyloid imaging of dutch-type hereditary cerebral amyloid angiopathy carriers

scientific article published on 12 August 2019

Amyloid β concentrations and stable isotope labeling kinetics of human plasma specific to central nervous system amyloidosis

artículo científico publicado en 2017

Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle

artículo científico publicado en 2009

Amyloid-beta isoform metabolism quantitation by stable isotope-labeled kinetics

artículo científico publicado en 2013

Amyloid-β Plaques in Clinical Alzheimer's Disease Brain Incorporate Stable Isotope Tracer In Vivo and Exhibit Nanoscale Heterogeneity

artículo científico publicado en 2018

Amyloid-β diurnal pattern: possible role of sleep in Alzheimer's disease pathogenesis

artículo científico publicado en 2014

Amyloid-β efflux from the central nervous system into the plasma

artículo científico publicado en 2014

Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls

artículo científico publicado en 2012

Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease

artículo científico publicado en 2012

An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice

artículo científico publicado en 2014

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

artículo científico publicado en 2019

An integrated multi-study analysis of intra-subject variability in cerebrospinal fluid amyloid-β concentrations collected by lumbar puncture and indwelling lumbar catheter

artículo científico publicado en 2015

Analysis of a compartmental model of amyloid beta production, irreversible loss and exchange in humans

artículo científico publicado en 2014

Another step forward in blood-based diagnostics for Alzheimer's disease

artículo científico publicado en 2020

Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease

artículo científico publicado en 2020

Are early atrophy patterns in autosomal dominant familial Alzheimer's disease gene-dependent?

article

Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease

scientific article published on 02 December 2019

Association of education with Aβ burden in preclinicial familial and sporadic Alzheimer disease

artículo científico publicado en 2020

Associations Between β-Amyloid Kinetics and the β-Amyloid Diurnal Pattern in the Central Nervous System

artículo científico publicado en 2016

Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease

artículo científico publicado en 2011

Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN)

scientific article published on 01 January 2020

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression

artículo científico publicado en 2019

BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease

artículo científico publicado en 2016

Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer's disease

artículo científico publicado en 2020

Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer's disease

artículo científico publicado en 2020

Brain and hippocampal rates of atrophy in familial Alzheimer's disease mutation carriers: Preliminary findings from the DIAN study

CAP--advancing the evaluation of preclinical Alzheimer disease treatments

artículo científico publicado en 2015

CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition.

artículo científico publicado en 2014

CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline

scholarly article by Marc Suárez-Calvet et al published December 2018 in EMBO Molecular Medicine

CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer's disease

artículo científico publicado en 2020

Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease

artículo científico publicado en 2015

Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer's disease and PET amyloid-positive patient identification

artículo científico publicado en 2020

Challenges, solutions, and recommendations for Alzheimer's disease combination therapy

artículo científico publicado en 2016

Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease

artículo científico publicado en 2016

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

artículo científico publicado en 2012

Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease

artículo científico publicado en 2016

Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease

artículo científico publicado en 2019

Collaboration for Alzheimer's Prevention: Principles to guide data and sample sharing in preclinical Alzheimer's disease trials

artículo científico publicado en 2016

Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease

artículo científico publicado en 2020

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies

article

Continuous 24-hour leptin, proopiomelanocortin, and amino acid measurements in human cerebrospinal fluid: correlations with plasma leptin, soluble leptin receptor, and amino acid levels

artículo científico publicado en 2014

Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Ratesin the CNS.

artículo científico publicado en 2012

Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group

artículo científico publicado en 2016

Cross-sectional and longitudinal associations between plasma neurodegenerative biomarkers and physical performance among community-dwelling older adults

artículo científico publicado en 2020

Cross-sectional cerebral volumetric differences and associations with estimated time to age-at-onset in familial Alzheimer's disease: Findings from the DIAN study

article

Data-driven models of dominantly-inherited Alzheimer's disease progression

artículo científico publicado en 2018

Data-driven models of dominantly-inherited Alzheimer's disease progression

scholarly article published 19 January 2018

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease

artículo científico publicado en 2017

Decreased clearance of CNS beta-amyloid in Alzheimer's disease

artículo científico publicado en 2010

Decreased platelet APP isoform ratios in autosomal dominant Alzheimer's disease: baseline data from a DIAN cohort subset

artículo científico publicado en 2015

Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network

artículo científico publicado en 2012

Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer's Disease: Results of the DIAN Study

artículo científico publicado en 2015

Discovery and validation of autosomal dominant Alzheimer's disease mutations

artículo científico publicado en 2018

Disruption of the sleep-wake cycle and diurnal fluctuation of β-amyloid in mice with Alzheimer's disease pathology

artículo científico publicado en 2012

Diurnal oscillation of CSF Aβ and other AD biomarkers

artículo científico publicado en 2017

Diurnal patterns of soluble amyloid precursor protein metabolites in the human central nervous system

artículo científico publicado en 2014

Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain.

artículo científico publicado en 2017

Dominantly Inherited Alzheimer Network: facilitating research and clinical trials

artículo científico publicado en 2013

Dominantly inherited Alzheimer's disease in Latin America: Genetic heterogeneity and clinical phenotypes

artículo científico publicado en 2020

Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network

artículo científico publicado en 2015

Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury

artículo científico publicado en 2016

Effect of BDNFVal66Met on disease markers in dominantly inherited Alzheimer's disease

scientific article published on 25 August 2018

Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network

scientific article published on 13 October 2018

Effect of sleep on overnight CSF amyloid-β kinetics.

artículo científico publicado en 2017

Effects of age and amyloid deposition on Aβ dynamics in the human central nervous system

artículo científico publicado en 2011

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease

artículo científico publicado en 2019

Estimating diagnostic accuracy for clustered ordinal diagnostic groups in the three-class case-Application to the early diagnosis of Alzheimer disease

artículo científico publicado en 2017

Exposure of the lysine in the gamma chain dodecapeptide of human fibrinogen is not enhanced by adsorption to poly(ethylene terephthalate) as measured by biotinylation and mass spectrometry

artículo científico publicado en 2011

Factors Contributing to the Post-Lumbar Puncture Headache—Reply

artículo científico publicado en 2015

Factors associated with the onset and persistence of post-lumbar puncture headache

artículo científico publicado en 2015

Fluctuations of CSF amyloid-beta levels: implications for a diagnostic and therapeutic biomarker

artículo científico publicado en 2007

Functional connectivity in autosomal dominant and late-onset Alzheimer disease

artículo científico publicado en 2014

Gantenerumab reduces amyloid-β plaques in patients with prodromal to moderate Alzheimer's disease: a PET substudy interim analysis

scientific article published on 12 December 2019

Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.

artículo científico publicado en 2018

Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer's disease

artículo científico publicado en 2017

High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis

scientific article published on 01 August 2019

Human Central Nervous System (CNS) ApoE Isoforms Are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared with Plasma

artículo científico publicado en 2016

Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo

artículo científico publicado en 2006

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

artículo científico publicado en 2011

Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network

artículo científico publicado en 2018

Impaired default network functional connectivity in autosomal dominant Alzheimer disease

artículo científico publicado en 2013

In vivo human apolipoprotein E isoform fractional turnover rates in the CNS

artículo científico publicado en 2012

In vivo kinetic approach reveals slow SOD1 turnover in the CNS.

artículo científico publicado en 2015

Increased Cerebrospinal Fluid Amyloid-β During Sleep Deprivation in Healthy Middle-Aged Adults Is Not Due to Stress or Circadian Disruption

artículo científico publicado en 2020

Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers

artículo científico publicado en 2013

Intra- and Inter-individual Variability of microRNA Levels in Human Cerebrospinal Fluid: Critical Implications for Biomarker Discovery

artículo científico publicado en 2017

Item response theory analysis of the Clinical Dementia Rating

artículo científico publicado en 2020

LONGITUDINAL ATROPHY IN AUTOSOMAL DOMINANT AD AND SPORADIC AD: LESSONS FROM DIAN

Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease

artículo científico publicado en 2018

Linear Combinations of Multiple Outcome Measures to Improve the Power of Efficacy Analysis ---Application to Clinical Trials on Early Stage Alzheimer Disease

artículo científico publicado en 2017

Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease

artículo científico publicado en 2014

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

artículo científico publicado en 2018

Loss of Brain Aerobic Glycolysis in Normal Human Aging.

artículo científico publicado en 2017

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

artículo científico publicado en 2006

Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism.

artículo científico publicado en 2006

Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling

artículo científico publicado en 2012

Measuring target effect of proposed disease-modifying therapies in Alzheimer's disease

artículo científico publicado en 2008

Method for the simultaneous quantitation of apolipoprotein E isoforms using tandem mass spectrometry

artículo científico publicado en 2009

Microglia Implicated in Tauopathy in the Striatum of Neurodegenerative Disease Patients from Genotype to Phenotype

scientific article published on 22 August 2020

Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer's disease subjects

artículo científico publicado en 2012

Neurofilament light chain levels in ventricular cerebrospinal fluid after acute aneurysmal subarachnoid haemorrhage.

scientific article published on 22 June 2010

Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).

artículo científico publicado en 2016

Neuropathologic assessment of participants in two multi-center longitudinal observational studies: the Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN).

artículo científico publicado en 2015

Partial volume correction in quantitative amyloid imaging

artículo científico publicado en 2014

Persistent metabolic youth in the aging female brain

artículo científico publicado en 2019

Phospho-tau with subthreshold tau-PET predicts increased tau accumulation rates in amyloid-positive individuals

artículo científico publicado en 2022

Plasma Aβ and neurofilament light chain are associated with cognitive and physical function decline in non-dementia older adults

artículo científico publicado en 2020

Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study

scientific article published on 21 January 2016

Preclinical and Clinical Development of ABBV-8E12, a Humanized Anti-Tau Antibody, for Treatment of Alzheimer's Disease and Other Tauopathies

artículo científico publicado en 2017

Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial.

artículo científico publicado en 2013

Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning

scientific article published on 11 February 2020

Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing

artículo científico publicado en 2018

Presymptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy-Related Blood Metabolite Alterations

scientific article published on 24 December 2020

Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study.

artículo científico publicado en 2017

Prioritized research recommendations from the National Institute of Neurological Disorders and Stroke Parkinson's Disease 2014 conference

artículo científico publicado en 2014

Protein production is an early biomarker for RNA-targeted therapies

scientific article published on 14 October 2018

Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease

artículo científico publicado en 2018

Pupil response biomarkers distinguish amyloid precursor protein mutation carriers from non-carriers

artículo científico publicado en 2013

Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group

artículo científico publicado en 2016

Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain

scientific article published on 27 August 2020

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

artículo científico publicado en 2013

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease

artículo científico publicado en 2018

Relationships between big-five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease

scientific article published on 23 June 2020

Reply

Reply to "Excess amyloid beta can be degraded in healthy humans".

artículo científico publicado en 2018

Reply to comment on "An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice".

artículo científico publicado en 2014

Reply to: Fractional synthesis and clearance rates for amyloid β

Revolutionizing Alzheimer's disease and clinical trials through biomarkers

artículo científico publicado en 2015

SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases

scientific article published on 20 June 2019

Seizures as an early symptom of autosomal dominant Alzheimer's disease

artículo científico publicado en 2018

Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study

artículo científico publicado en 2020

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

artículo científico publicado en 2019

Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease

scientific article published on 06 June 2020

Simultaneously evaluating the effect of baseline levels and longitudinal changes in disease biomarkers on cognition in dominantly inherited Alzheimer's disease

scholarly article by Guoqiao Wang et al published 2018 in Alzheimer's & dementia (New York, N. Y.)

Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease

scientific article published on 15 July 2020

Sleep Deprivation Affects Tau Phosphorylation in Human Cerebrospinal Fluid

artículo científico publicado en 2020

Soluble Amyloid-beta Aggregates from Human Alzheimer's Disease Brains

artículo científico publicado en 2016

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

artículo científico publicado en 2018

Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates

artículo científico publicado en 2007

Stable isotope labeling tandem mass spectrometry (SILT): integration with peptide identification and extension to data-dependent scans

artículo científico publicado en 2008

Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset

artículo científico publicado en 2019

Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis

artículo científico publicado en 2014

Tau Kinetics in Neurons and the Human Central Nervous System

artículo científico publicado en 2018

Tau Kinetics in Neurons and the Human Central Nervous System

scientific article published on 01 May 2018

Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers

scientific article published on 01 April 2019

Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer's Disease.

artículo científico publicado en 2019

Tau Positron Emission Tomography in Autosomal Dominant Alzheimer Disease: Small Windows, Big Picture

artículo científico publicado en 2018

Testing a test for Alzheimer disease

artículo científico publicado en 2007

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease

scientific article published on 21 March 2019

The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model

artículo científico publicado en 2016

The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkey.

artículo científico publicado en 2017

The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study

artículo científico publicado en 2013

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease

scholarly article by Daniel Twohig et al published 26 November 2018 in Acta neuropathologica communications

The structure of amyloid-β dimers in Alzheimer's disease brain: a step forward for oligomers

scientific article published on 01 May 2019

Two-period linear mixed effects models to analyze clinical trials with run-in data when the primary outcome is continuous: Applications to Alzheimer's disease

scientific article published on 05 September 2019

Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease

artículo científico publicado en 2018

Validity and power of minimization algorithm in longitudinal analysis of clinical trials

scientific article published on 13 June 2017

Visual involvement in corticobasal syndrome

artículo científico

White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease

article by Miguel Ángel Araque Caballero et al published 1 October 2018 in Brain

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease

artículo científico publicado en 2018

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

artículo científico publicado en 2016

β-amyloid dynamics in human plasma

artículo científico publicado en 2012

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