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Lista de obras de Kazuhiko Igarashi

A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors

artículo científico publicado en 2017

A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain

artículo científico publicado en 2000

Ablation of the bach1 gene leads to the suppression of atherosclerosis in bach1 and apolipoprotein E double knockout mice

artículo científico publicado en 2008

Abundant Expression of Erythroid Transcription Factor P45 NF-E2 mRNA in Human Peripheral Granurocytes

artículo científico publicado en 1996

Actin Family Proteins in the Human INO80 Chromatin Remodeling Complex Exhibit Functional Roles in the Induction of Heme Oxygenase-1 with Hemin

artículo científico publicado en 2017

Activation of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with promyelocytic leukemia nuclear bodies

artículo científico publicado en 2002

Activation of the SUMO modification system is required for the accumulation of RAD51 at sites of DNA damage

artículo científico publicado en 2013

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

artículo científico publicado el 18 de julio de 1997

Architecture and dynamics of the transcription factor network that regulates B-to-plasma cell differentiation

artículo científico publicado en 2007

Association between BACH2 expression and clinical prognosis in diffuse large B-cell lymphoma

artículo científico publicado en 2014

B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs

artículo científico publicado en 2003

BACH transcription factors in innate and adaptive immunity

artículo científico publicado en 2017

BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint

artículo científico publicado en 2013

BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers

artículo científico publicado en 2016

BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis.

artículo científico publicado en 2013

BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice

scientific article published on 01 March 2013

Bach1 as a regulator of mitosis, beyond its transcriptional function

artículo científico publicado en 2012

Bach1 deficiency ameliorates hepatic injury in a mouse model

artículo científico publicado en 2009

Bach1 deficiency and accompanying overexpression of heme oxygenase-1 do not influence aging or tumorigenesis in mice.

artículo científico publicado en 2014

Bach1 deficiency protects pancreatic β-cells from oxidative stress injury

artículo científico publicado en 2013

Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1

artículo científico publicado en 2015

Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells

artículo científico publicado en 2003

Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model

artículo científico publicado en 2010

Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin

artículo científico publicado en 2008

Bach1 is critical for the transformation of mouse embryonic fibroblasts by Ras(V12) and maintains ERK signaling

artículo científico publicado en 2012

Bach1 modulates heme oxygenase-1 expression in the neonatal mouse lung

scientific article published on February 2009

Bach1 promotes muscle regeneration through repressing Smad-mediated inhibition of myoblast differentiation

artículo científico publicado en 2020

Bach1 regulates osteoclastogenesis in a mouse model via both heme oxygenase 1-dependent and heme oxygenase 1-independent pathways

artículo científico publicado en 2012

Bach1 repression of ferritin and thioredoxin reductase1 is heme-sensitive in cells and in vitro and coordinates expression with heme oxygenase1, beta-globin, and NADP(H) quinone (oxido) reductase1.

artículo científico publicado en 2007

Bach1, a heme-dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure

artículo científico publicado en 2007

Bach1-dependent and -independent regulation of heme oxygenase-1 in keratinocytes

artículo científico publicado en 2010

Bach1-mediated suppression of p53 is inhibited by p19ARF independently of MDM2

artículo científico publicado en 2012

Bach2 Controls Homeostasis of Eosinophils by Restricting the Type-2 Helper Function of T Cells

artículo científico publicado en 2017

Bach2 Promotes B Cell Receptor-Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors.

artículo científico publicado en 2018

Bach2 maintains T cells in a naive state by suppressing effector memory-related genes

artículo científico publicado en 2013

Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch

artículo científico publicado en 2010

Bcr-Abl signaling through the PI-3/S6 kinase pathway inhibits nuclear translocation of the transcription factor Bach2, which represses the antiapoptotic factor heme oxygenase-1.

artículo científico publicado en 2006

Bipartite functional map of the E. coli RNA polymerase α subunit: Involvement of the C-terminal region in transcription activation by cAMP-CRP

scientific article published on 01 June 1991

Cancer and epigenetics - basic research and clinical implications: Joint Meeting of the Fourteenth International Symposium of the Hiroshima Cancer Seminar and the Eighth Meeting of the Tottori Bioscience Promotion Foundation, October 2004

artículo científico publicado en 2005

Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling comp

artículo científico publicado en 2009

Charge-state-distribution analysis of Bach2 intrinsically disordered heme binding region

artículo científico publicado en 2016

Cloning of a coproporphyrinogen oxidase promoter regulatory element binding protein

artículo científico publicado en 2000

Co-repressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression

artículo científico publicado en 2007

Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective

scientific article published on 01 February 2020

Collagen V Is a Potential Substrate for Clostridial Collagenase G in Pancreatic Islet Isolation

artículo científico publicado en 2016

Collagenase H is crucial for isolation of rat pancreatic islets

artículo científico publicado en 2013

Conditional expression of the ubiquitous transcription factor MafK induces erythroleukemia cell differentiation

artículo científico publicado el 1 de agosto de 1995

Corrigendum to “Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism” [FEBS Letters 586 (2012) 448-454]

scholarly article published in FEBS Letters

Crystal structure of the Bach1 BTB domain and its regulation of homodimerization

scientific journal article

DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics

artículo científico publicado en 2007

Differential gene expression profiling between wild-type and ALAS2-null erythroblasts: identification of novel heme-regulated genes.

artículo científico publicado en 2005

Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells

artículo científico publicado en 2017

Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines

artículo científico publicado en 2006

Duodenal follicular lymphoma lacks AID but expresses BACH2 and has memory B-cell characteristics

artículo científico publicado en 2012

Dynamic changes in transcription factor complexes during erythroid differentiation revealed by quantitative proteomics

artículo científico publicado en 2003

Dynamic cytoplasmic anchoring of the transcription factor Bach1 by intracellular hyaluronic acid binding protein IHABP

artículo científico publicado en 2005

Effects of genetic ablation of bach1 upon smooth muscle cell proliferation and atherosclerosis after cuff injury

artículo científico publicado en 2005

Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3.

artículo científico publicado en 2016

Epitope mapping and functional characterization of monoclonal antibodies specific for the alpha subunit of Escherichia coli RNA polymerase

artículo científico publicado en 1994

Erratum: Duodenal follicular lymphoma lacks AID but expresses BACH2 and has memory B-cell characteristics

scholarly article published in Modern Pathology

Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1

scientific article published on 18 November 2019

Fission yeast homologues of the B' subunit of protein phosphatase 2A: multiple roles in mitotic cell division and functional interaction with calcineurin

artículo científico publicado en 2001

Frequent downregulation of BTB and CNC homology 2 expression in Epstein-Barr virus-positive diffuse large B-cell lymphoma.

artículo científico publicado en 2017

Functional map of the alpha subunit of Escherichia coli RNA polymerase: two modes of transcription activation by positive factors

artículo científico publicado el 15 de octubre de 1991

Functional specialization within the α-subunit of Escherichia coli RNA polymerase

artículo científico publicado en 1991

Genetic Ablation of Transcription Repressor Bach1 Reduces Neural Tissue Damage and Improves Locomotor Function after Spinal Cord Injury in Mice

artículo científico publicado en 2009

Genetic ablation of Bach1 gene enhances recovery from hyperoxic lung injury in newborn mice via transient upregulation of inflammatory genes

artículo científico publicado en 2017

Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: role of IL-6.

artículo científico publicado en 2009

Genetic ablation of the transcription repressor Bach1 leads to myocardial protection against ischemia/reperfusion in mice

artículo científico publicado en 2006

Genetic complementation analysis showed distinct contributions of the N-terminal tail of H2A.Z to epigenetic regulations

artículo científico publicado en 2016

Genetic heterogeneity in 26 infants with a hypomyelinating leukodystrophy

artículo científico publicado en 2015

Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1-Pparg pathway in adipogenesis

artículo científico publicado en 2016

Glucocorticoid receptor signaling represses the antioxidant response by inhibiting histone acetylation mediated by the transcriptional activator NRF2.

artículo científico publicado en 2017

Heme binds to an intrinsically disordered region of Bach2 and alters its conformation

artículo científico publicado en 2014

Heme induces ubiquitination and degradation of the transcription factor Bach1

artículo científico publicado en 2007

Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1

artículo científico publicado en 2001

Heme oxygenase-1 gene enhancer manifests silencing activity in a chromatin environment prior to oxidative stress

artículo científico

Heme positively regulates the expression of beta-globin at the locus control region via the transcriptional factor Bach1 in erythroid cells

artículo científico publicado en 2004

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2.

artículo científico publicado en 2011

Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1

artículo científico publicado en 2004

Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network

artículo científico publicado en 2004

Heme-Regulated Transcription Factor Bach1

Heme-dependent up-regulation of the alpha-globin gene expression by transcriptional repressor Bach1 in erythroid cells

artículo científico publicado en 2004

Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages

artículo científico publicado en 2014

Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation

artículo científico publicado en 2014

Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene

artículo científico publicado en 2002

High Fractional Occupancy of a Tandem Maf Recognition Element and Its Role in Long-Range β-Globin Gene Regulation

artículo científico publicado en 2015

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1

artículo científico publicado en 2021

Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer.

artículo científico publicado en 1998

Identification of a subunit assembly domain in the alpha subunit of Escherichia coli RNA polymerase.

artículo científico publicado en 1991

Identification of senescence-associated genes and their networks under oxidative stress by the analysis of Bach1.

artículo científico publicado en 2011

Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK2.

artículo científico publicado en 2017

Infection perturbs Bach2- and Bach1-dependent erythroid lineage 'choice' to cause anemia

artículo científico publicado en 2018

Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis

artículo científico publicado en 2017

Interaction and cooperation of mi transcription factor (MITF) and myc-associated zinc-finger protein-related factor (MAZR) for transcription of mouse mast cell protease 6 gene

artículo científico publicado en 2002

Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency

artículo científico publicado en 2016

MafB as a type I interferon rheostat

scientific article published on 01 August 2010

Mapping the cAMP receptor protein contact site on the alpha subunit of Escherichia coli RNA polymerase

artículo científico publicado el 1 de septiembre de 1992

Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation

artículo científico publicado en 2015

Metabolic aspects of epigenome: coupling of S-adenosylmethionine synthesis and gene regulation on chromatin by SAMIT module

artículo científico

Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein

artículo científico publicado en 2011

Methionine adenosyltransferase II-dependent histone H3K9 methylation at the COX-2 gene locus

artículo científico publicado en 2013

MiR-196a regulates heme oxygenase-1 by silencing Bach1 in the neonatal mouse lung

artículo científico publicado en 2016

Microproteomics with microfluidic-based cell sorting: Application to 1000 and 100 immune cells

artículo científico publicado en 2017

Mitochondrial function provides instructive signals for activation-induced B-cell fates

artículo científico publicado en 2015

Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1.

artículo científico publicado en 2008

Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3

artículo científico publicado en 1999

Multifunctional human transcriptional coactivator protein PC4 is a substrate of Aurora kinases and activates the Aurora enzymes

artículo científico publicado en 2016

Multivalent DNA Binding Complex Generated by Small Maf and Bach1 as a Possible Biochemical Basis for β-Globin Locus Control Region Complex

artículo científico publicado en 1998

Myocardial protection against pressure overload in mice lacking Bach1, a transcriptional repressor of heme oxygenase-1.

artículo científico publicado en 2008

N 1-methyladenosine (m1A) RNA modification: the key to ribosome control?

scientific article published on 04 March 2020

Nuclear positioning of the BACH2 gene in BCR-ABL positive leukemic cells

artículo científico publicado en 2007

Orchestration of B lymphoid cells and their inner myeloid by Bach

artículo científico publicado en 2016

Orchestration of plasma cell differentiation by Bach2 and its gene regulatory network

artículo científico publicado en 2014

Over-expression of BACH2 is related to ongoing somatic hypermutation of the immunoglobulin heavy chain gene variable region of de novo diffuse large B-cell lymphoma

artículo científico publicado en 2013

Oxidative stress reaction in the meniscus of Bach 1 deficient mice: potential prevention of meniscal degeneration

artículo científico publicado en 2008

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

artículo científico publicado en 2004

Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.

artículo científico publicado en 2018

Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells

artículo científico

Posttranscriptional regulation of US11 in cells infected with a herpes simplex virus 1 recombinant lacking both 222-bp domains containing S-component origins of DNA synthesis

artículo científico publicado en 1999

Prognostic significance of BACH2 expression in diffuse large B-cell lymphoma: a study of the Osaka Lymphoma Study Group

artículo científico publicado en 2005

Proline cis/trans-isomerase Pin1 regulates peroxisome proliferator-activated receptor gamma activity through the direct binding to the activation function-1 domain

artículo científico publicado en 2009

Reconstitution of human beta-globin locus control region hypersensitive sites in the absence of chromatin assembly.

artículo científico publicado en 2001

Regulation of NF-E2 activity in erythroleukemia cell differentiation

artículo científico publicado en 1998

Regulation of heme oxygenase-1 by transcription factor Bach1 in the mouse brain

scientific article published on 26 April 2008

Regulation of heme oxygenase-1 gene transcription: recent advances and highlights from the International Conference (Uppsala, 2003) on Heme Oxygenase

artículo científico publicado en 2004

Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6.

artículo científico publicado en 2008

Regulatory signatures of liver regeneration distilled by integrative analysis of mRNA, histone methylation, and proteomics

artículo científico publicado en 2017

Repression of PML nuclear body-associated transcription by oxidative stress-activated Bach2

artículo científico publicado en 2004

SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites

artículo científico publicado en 2017

Sequence analysis of two temperature-sensitive mutations in the alpha subunit gene (rpoA) of Escherichia coli RNA polymerase.

artículo científico publicado en 1990

Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response

artículo científico publicado en 2003

Solution structure of clostridial collagenase H and its calcium-dependent global conformation change

artículo científico publicado en 2013

Stimulation of the phage lambda pL promoter by integration host factor requires the carboxy terminus of the alpha-subunit of RNA polymerase

artículo científico publicado el 20 de octubre de 1992

Study profile of The Tohoku Medical Megabank Community-Based Cohort Study

artículo científico publicado en 2020

Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency

Synergistic Effect of Neutral Protease and Clostripain on Rat Pancreatic Islet Isolation.

artículo científico publicado en 2015

The Ada protein is a class I transcription factor of Escherichia coli

artículo científico publicado en 1993

The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif

artículo científico publicado en 2014

The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression

artículo científico publicado en 2015

The Tohoku Medical Megabank Project: Design and Mission

scientific article published on 02 July 2016

The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization

artículo científico publicado en 2015

The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes

artículo científico

The double knockout of Bach1 and Bach2 in mice reveals shared compensatory mechanisms in regulating alveolar macrophage function and lung surfactant homeostasis

artículo científico publicado en 2016

The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation

artículo científico publicado en 2006

The mTOR-Bach2 Cascade Controls Cell Cycle and Class Switch Recombination during B Cell Differentiation

artículo científico publicado en 2017

The mobility of Bach2 nuclear foci is regulated by SUMO-1 modification

artículo científico publicado en 2007

The superoxide-producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells

artículo científico publicado en 2005

The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program

artículo científico publicado en 2014

The transcriptional programme of antibody class switching involves the repressor Bach2.

artículo científico publicado en 2004

The world according to Maf

artículo científico publicado en 1997

Transcription factor BACH1 is recruited to the nucleus by its novel alternative spliced isoform

artículo científico publicado en 2001

Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function

artículo científico publicado en 2013

Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism

artículo científico publicado en 2012

Transcriptional suppression of BACH2 by the Bcr-Abl oncoprotein is mediated by PAX5.

artículo científico publicado en 2012

Transforming growth factor-β induces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.

artículo científico publicado en 2013

Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment

artículo científico publicado en 2005

Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair

artículo científico publicado en 2016

Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population

artículo científico publicado en 2014

Wearing red for signaling: the heme-bach axis in heme metabolism, oxidative stress response and iron immunology

artículo científico publicado en 2014

[Extensive analysis of protein phosphorylation: An example of transcription factor Bach2].

artículo científico publicado en 2016

beta-Carotene and cigarette smoke condensate regulate heme oxygenase-1 and its repressor factor Bach1: relationship with cell growth

scientific journal article