Lista de obras - Arnaud Jacquel - Dominio Público Uruguay

A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function

artículo científico publicado en 2014

A role for caspases in the differentiation of erythroid cells and macrophages.

artículo científico publicado en 2007

A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.

artículo científico publicado en 2006

ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.

artículo científico publicado en 2017

Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia

artículo científico publicado en 2019

All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to Ponatinib ⬇️

artículo científico publicado el 1 de diciembre de 2012

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

artículo científico publicado en 2009

Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition.

artículo científico publicado en 2006

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

artículo científico publicado en 2012

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

artículo científico publicado en 2016

CD271 is an imperfect marker for melanoma initiating cells.

artículo científico publicado en 2014

CXCL7 is a predictive marker of sunitinib efficacy in clear cell renal cell carcinomas

artículo científico publicado en 2017

Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice

artículo científico publicado en 2018

Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies

scientific article published on 16 October 2019

Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

artículo científico publicado en 2004

Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages

artículo científico publicado en 2009

Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34+ cells

artículo científico publicado en 2010

DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes

artículo científico publicado en 2016

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

artículo científico publicado en 2016

Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes

artículo científico publicado en 2014

Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.

artículo científico publicado en 2011

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

artículo científico publicado en 2021

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia

artículo científico publicado en 2015

Fine-tuning nucleophosmin in macrophage differentiation and activation.

artículo científico publicado en 2011

Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors.

artículo científico publicado en 2009

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.

artículo científico publicado en 2018

Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage.

artículo científico publicado en 2003

Imatinib mesylate (STI571) decreases the vascular endothelial growth factor plasma concentration in patients with chronic myeloid leukemia.

artículo científico publicado en 2004

Imatinib mesylate-resistant human chronic myelogenous leukemia cell lines exhibit high sensitivity to the phytoalexin resveratrol

artículo científico publicado en 2008

Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.

artículo científico publicado en 2012

Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation

scientific article published on 30 September 2018

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

artículo científico publicado en 2013

Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells.

artículo científico publicado en 2009

Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo

scientific article published on 16 May 2019

Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation

scientific journal article

LAMP2 expression dictates azacytidine response and prognosis in MDS/AML

artículo científico publicado en 2019

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.

artículo científico publicado en 2011

Mechanism of action of the multikinase inhibitor Foretinib.

artículo científico publicado en 2011

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells ⬇️

artículo científico publicado el 1 de noviembre de 2011

Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells

artículo científico publicado en 2009

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

artículo científico publicado en 2010

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

artículo científico publicado en 2014

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

artículo científico publicado en 2003

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

artículo científico publicado en 2015

Ponatinib circumvents all types of imatinib resistance in chronic myelogenous leukemia cell lines.

artículo científico publicado en 2013

Proper macrophagic differentiation requires both autophagy and caspase activation.

artículo científico publicado en 2012

Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases

artículo científico publicado en 2003

RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.

artículo científico publicado en 2017

Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance

artículo científico publicado en 2018

Reprogramming monocyte-derived macrophages through caspase inhibition

publication published on 30 December 2021

RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation

artículo científico publicado en 2006

Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia.

artículo científico publicado en 2017

Severe thymic atrophy in a mouse model of skin inflammation accounts for impaired TNFR1 signaling

artículo científico publicado en 2012

Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway

artículo científico publicado en 2012

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

artículo científico publicado en 2015

The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.

artículo científico publicado en 2012

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production ⬇️

artículo científico publicado el 4 de mayo de 2012

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.

artículo científico publicado en 2018

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.

artículo científico publicado en 2014

[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies]

artículo científico publicado en 2017

cIAPs and XIAP reduce RIPKs to silence.

artículo científico publicado en 2014

p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.

artículo científico publicado en 2006

Lista de obras de Arnaud Jacquel

A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function

A role for caspases in the differentiation of erythroid cells and macrophages.

A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.

ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.

Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia

All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to Ponatinib ⬇️

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition.

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

CD271 is an imperfect marker for melanoma initiating cells.

CXCL7 is a predictive marker of sunitinib efficacy in clear cell renal cell carcinomas

Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice

Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies

Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages

Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34+ cells

DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes

Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia

Fine-tuning nucleophosmin in macrophage differentiation and activation.

Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors.

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.

Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage.

Imatinib mesylate (STI571) decreases the vascular endothelial growth factor plasma concentration in patients with chronic myeloid leukemia.

Imatinib mesylate-resistant human chronic myelogenous leukemia cell lines exhibit high sensitivity to the phytoalexin resveratrol

Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.

Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells.

Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo

Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation

LAMP2 expression dictates azacytidine response and prognosis in MDS/AML

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.

Mechanism of action of the multikinase inhibitor Foretinib.

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells ⬇️

Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

Ponatinib circumvents all types of imatinib resistance in chronic myelogenous leukemia cell lines.

Proper macrophagic differentiation requires both autophagy and caspase activation.

Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases

RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.

Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance

Reprogramming monocyte-derived macrophages through caspase inhibition

RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation

Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia.

Severe thymic atrophy in a mouse model of skin inflammation accounts for impaired TNFR1 signaling

Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production ⬇️

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.

[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies]

cIAPs and XIAP reduce RIPKs to silence.

p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.