Filtros de búsqueda

Lista de obras de Holger Grohganz

A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin

artículo científico publicado en 2012

Adsorption of the decapeptide Cetrorelix depends both on the composition of dissolution medium and the type of solid surface

artículo científico publicado en 2004

Amino Acids as Co-amorphous Excipients for Simvastatin and Glibenclamide: Physical Properties and Stability

artículo científico publicado en 2014

Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement

artículo científico publicado en 2013

Amino acids as co-amorphous stabilizers for poorly water-soluble drugs--Part 2: molecular interactions.

artículo científico publicado en 2013

Amorphization within the tablet: Using microwave irradiation to form a glass solution in situ

artículo científico publicado en 2017

Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and l-Arginine.

artículo científico publicado en 2018

Aspartame as a co-former in co-amorphous systems

Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs

scientific article published on 01 September 2019

Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying.

artículo científico publicado en 2015

Classification of lyophilised mixtures using multivariate analysis of NIR spectra.

artículo científico publicado en 2009

Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions

article

Co-former selection for co-amorphous drug-amino acid formulations

artículo científico publicado en 2018

Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen.

artículo científico publicado en 2011

Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme.

artículo científico publicado en 2017

Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy

artículo científico publicado en 2012

Design space approach in the optimization of the spray-drying process

artículo científico publicado en 2011

Detecting phase separation of freeze-dried binary amorphous systems using pair-wise distribution function and multivariate data analysis.

artículo científico publicado en 2013

Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systems

artículo científico publicado en 2020

Development and in vitro evaluation of a liposome based implant formulation for the decapeptide cetrorelix

artículo científico publicado en 2005

Development and validation of a HPLC method for routine quantification of the decapeptide Cetrorelix in liposome dispersions

artículo científico publicado en 2004

Development of a screening method for co-amorphous formulations of drugs and amino acids.

artículo científico publicado en 2016

Dipeptides as co-formers in co-amorphous systems

scientific article published on 20 November 2018

Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy

artículo científico publicado en 2019

Emerging trends in the stabilization of amorphous drugs.

artículo científico publicado en 2012

Exploring the chemical space for freeze-drying excipients

scientific article published on 27 May 2019

Formation Mechanism of Coamorphous Drug-Amino Acid Mixtures.

artículo científico publicado en 2015

Formation of mannitol hemihydrate in freeze-dried protein formulations--a design of experiment approach

artículo científico publicado en 2013

Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations

artículo científico publicado en 2013

Glass Forming Ability of Amorphous Drugs Investigated by Continuous Cooling and Isothermal Transformation

artículo científico publicado en 2016

Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs

artículo científico publicado en 2018

Improvement of the physicochemical properties of Co-amorphous naproxen-indomethacin by naproxen-sodium

artículo científico publicado en 2017

Improving co-amorphous drug formulations by the addition of the highly water soluble amino Acid, proline

artículo científico publicado en 2014

In situ amorphisation of indomethacin with Eudragit® E during dissolution

artículo científico publicado en 2013

In situ co-amorphisation in coated tablets - The combination of carvedilol with aspartic acid during immersion in an acidic medium

scientific article published on 12 January 2019

In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium - a proof of concept study

artículo científico publicado en 2018

In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine

scientific article published on 25 September 2018

Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions

artículo científico publicado en 2019

Influence of PVP molecular weight on the microwave assisted in situ amorphization of indomethacin

artículo científico publicado en 2017

Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations

artículo científico publicado en 2018

Influence of preparation pathway on the glass forming ability

artículo científico publicado en 2017

Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids

artículo científico publicado en 2018

Influence of the cooling rate and the blend ratio on the physical stability of co-amorphous naproxen/indomethacin

artículo científico publicado en 2016

Influence of variation in molar ratio on co-amorphous drug-amino acid systems

artículo científico publicado en 2016

Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug–polymer mixtures

artículo científico publicado en 2013

Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling

artículo científico publicado en 2015

Is there a correlation between the glass forming ability of a drug and its supersaturation propensity?

artículo científico publicado en 2018

Large-Scale Biophysical Evaluation of Protein PEGylation Effects: In Vitro Properties of 61 Protein Entities

artículo científico publicado en 2016

Multivariate Quantification of the Solid State Phase Composition of Co-Amorphous Naproxen-Indomethacin.

artículo científico publicado en 2015

Multivariate analysis of phenol in freeze-dried and spray-dried insulin formulations by NIR and FTIR

artículo científico publicado en 2011

Near-infrared imaging for high-throughput screening of moisture induced changes in freeze-dried formulations

artículo científico publicado en 2014

On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems

artículo científico publicado en 2017

Organic acids as co-formers for co-amorphous systems - Influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems

artículo científico publicado en 2018

Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine

artículo científico publicado en 2017

Preparation and characterization of spray-dried co-amorphous drug-amino acid salts

artículo científico publicado en 2015

Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin

artículo científico publicado en 2016

Preparation of Co-Amorphous Systems by Freeze-Drying

scientific article published on 30 September 2020

Probing Pharmaceutical Mixtures during Milling: The Potency of Low-Frequency Raman Spectroscopy in Identifying Disorder.

artículo científico publicado en 2017

Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations

artículo científico publicado en 2019

Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage.

artículo científico publicado en 2016

Quality by design approach in the optimization of the spray-drying process.

artículo científico publicado en 2011

Rapid solid-state analysis of freeze-dried protein formulations using NIR and Raman spectroscopies

artículo científico publicado en 2011

Recent advances in co-amorphous drug formulations

artículo científico publicado en 2016

Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients.

artículo científico publicado en 2009

Refining stability and dissolution rate of amorphous drug formulations

artículo científico publicado en 2014

Role of excipients in the quantification of water in lyophilised mixtures using NIR spectroscopy

artículo científico publicado en 2009

Solid state properties and drug release behavior of co-amorphous indomethacin-arginine tablets coated with Kollicoat® Protect

artículo científico publicado en 2017

Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin–arginine

artículo científico publicado en 2015

Supersaturating drug delivery systems: The potential of co-amorphous drug formulations.

artículo científico publicado en 2017

Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery

scientific article published on 12 March 2017

The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

artículo científico publicado en 2018

The Role of Glass Transition Temperatures in Coamorphous Drug–Amino Acid Formulations

scientific article published on 30 July 2018

The impact of surface- and nano-crystallisation on the detected amorphous content and the dissolution behaviour of amorphous indomethacin

artículo científico publicado en 2012

The influence of lysozyme on mannitol polymorphism in freeze-dried and spray-dried formulations depends on the selection of the drying process

artículo científico publicado en 2013

The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation

artículo científico publicado en 2017

The use of molecular descriptors in the development of co-amorphous formulations.

artículo científico publicado en 2018

Towards a robust water content determination of freeze-dried samples by near-infrared spectroscopy

artículo científico publicado en 2010

Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems

artículo científico publicado en 2019

Undesired co-amorphisation of indomethacin and arginine during combined storage at high humidity conditions

artículo científico publicado en 2018

Unintended and in situ amorphisation of pharmaceuticals.

artículo científico

Using dextran of different molecular weights to achieve faster freeze-drying and improved storage stability of lactate dehydrogenase

scientific article published on 20 June 2018

Well-plate freeze-drying: a high throughput platform for screening of physical properties of freeze-dried formulations

artículo científico publicado en 2014

Whey proteins as stabilizers in amorphous solid dispersions

artículo científico publicado en 2018

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda