Lista de obras - Shamshad Cockcroft - Dominio Público Uruguay

14-3-3 protein and ATRAP bind to the soluble class IIB phosphatidylinositol transfer protein RdgBβ at distinct sites.

artículo científico publicado en 2012

A modified procedure for thin-layer chromatography of phospholipids

artículo científico publicado en 1982

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport.

artículo científico publicado en 2015

A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum.

artículo científico publicado en 2009

ADP ribosylation factor 1 mutants identify a phospholipase D effector region and reveal that phospholipase D participates in lysosomal secretion but is not sufficient for recruitment of coatomer I.

artículo científico publicado en 1999

ADP-ribosylation factor 1-regulated phospholipase D activity is localized at the plasma membrane and intracellular organelles in HL60 cells.

artículo científico publicado en 1996

ADP-ribosylation factor and Rho proteins mediate fMLP-dependent activation of phospholipase D in human neutrophils

artículo científico publicado en 1998

ADP-ribosylation-factor-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following N-formylmethionyl-leucyl-phenylalanine stimulation of human neutrophils.

artículo científico publicado en 1997

ARF and PITP restore GTPγS-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis

scientific article published on 01 June 1996

ARF-regulated phospholipase D: a potential role in membrane traffic

artículo científico publicado en 1996

ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts

artículo científico publicado en 1998

ARF1(2-17) does not specifically interact with ARF1-dependent pathways. Inhibition by peptide of phospholipases C beta, D and exocytosis in HL60 cells

scientific article published on 01 July 1994

ARF1-regulated phospholipase D in human neutrophils is enhanced by PMA and MgATP

scientific article published on 01 September 1994

ATP induces nucleotide permeability in rat mast cells

scientific journal article

ATP stimulates secretion in human neutrophils and HL60 cells via a pertussis toxin-sensitive guanine nucleotide-binding protein coupled to phospholipase C

artículo científico publicado en 1989

Activation and inhibition of calcium-dependent histamine secretion by ATP ions applied to rat mast cells ⬇️

artículo científico publicado el 1 de noviembre de 1979

Activation of exocytosis by cross-linking of the IgE receptor is dependent on ADP-ribosylation factor 1-regulated phospholipase D in RBL-2H3 mast cells: evidence that the mechanism of activation is via regulation of phosphatidylinositol [...]

scientific journal article

Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha.

artículo científico publicado en 2004

An essential role for phosphatidylinositol transfer protein in phospholipase C-Mediated inositol lipid signaling

scientific article published on 01 September 1993

Biochemical and biological functions of class I phosphatidylinositol transfer proteins

artículo científico publicado en 2007

Breakdown and synthesis of polyphosphoinositides in fMetLeuPhe-stimulated neutrophils

scientific article published on 01 February 1985

Bromoenol lactone, an inhibitor of Group V1A calcium-independent phospholipase A2 inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx

artículo científico publicado en 2006

Ca2+-dependent conversion of phosphatidylinositol to phosphatidate in neutrophils stimulated with fMet-Leu-Phe or ionophore A23187

artículo científico publicado en 1984

Characterization of fMet-Leu-Phe-stimulated phospholipase C in streptolysin-O-permeabilised cells

artículo científico publicado en 1991

Chemotactic peptide stimulation of arachidonic acid release in HL60 cells, an interaction between G protein and phospholipase C mediated signal transduction

artículo científico publicado en 1991

Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in the formylmethionyl-leucylphenylalanine-dependent production of phosphatidylinositol 3,4,5-trisphosphate in human neutrophils

artículo científico publicado en 1997

Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in vitro

artículo científico publicado en 2002

Compartmentalized signalling in neurons

artículo científico publicado en 2007

Continual production of phosphatidic acid by phospholipase D is essential for antigen-stimulated membrane ruffling in cultured mast cells

artículo científico publicado en 2002

Contrasting roles for receptor-stimulated inositol lipid metabolism in secretory cells ⬇️

artículo científico publicado el 1 de diciembre de 1984

Correlation between secretion and phospholipase D activation in differentiated HL60 cells.

artículo científico publicado en 1993

Crystallization and preliminary X-ray diffraction studies on ADP-ribosylation factor 1

artículo científico publicado en 1994

Current thoughts on the phosphatidylinositol transfer protein family

artículo científico publicado en 2002

Deletion of 24 amino acids from the C-terminus of phosphatidylinositol transfer protein causes loss of phospholipase C-mediated inositol lipid signalling

artículo científico publicado en 1997

Didecanoyl phosphatidylcholine is a superior substrate for assaying mammalian phospholipase D.

artículo científico publicado en 1996

Differential control of azurophilic and specific granule exocytosis in Sendai-virus-permeabilized rabbit neutrophils

artículo científico publicado en 1987

Differential expression of a C-terminal splice variant of phosphatidylinositol transfer protein beta lacking the constitutive-phosphorylated Ser262 that localizes to the Golgi compartment.

artículo científico publicado en 2006

Dual role for guanine nucleotides in stimulus-secretion coupling

artículo científico publicado en 1986

Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells

artículo científico publicado en 2008

EGF regulation of PITP dynamics is blocked by inhibitors of phospholipase C and of the Ras-MAP kinase pathway

artículo científico publicado en 2003

Early events in the activation of Ca2+ dependent secretion: studies with rat peritoneal mast cells

scientific article published on 01 September 1980

Effect of H-ras proteins on the activity of polyphosphoinositide phospholipase C in HL60 membranes

artículo científico publicado en 1990

Endogenous phospholipase D2 localizes to the plasma membrane of RBL-2H3 mast cells and can be distinguished from ADP ribosylation factor-stimulated phospholipase D1 activity by its specific sensitivity to oleic acid

artículo científico publicado en 2003

Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells

artículo científico publicado en 1987

Evidence for a role of phosphatidylinositol turnover in stimulus–secretion coupling. Studies with rat peritoneal mast cells ⬇️

artículo científico publicado el 15 de marzo de 1979

Fluoxetine elevates allopregnanolone in female rat brain but inhibits a steroid microsomal dehydrogenase rather than activating an aldo-keto reductase.

artículo científico publicado en 2014

Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?

scientific article published on 31 January 2011

Guanine nucleotides stimulate polyphosphoinositide phosphodiesterase and exocytotic secretion from HL60 cells permeabilized with streptolysin O.

artículo científico publicado en 1988

Human ITPK1: a reversible inositol phosphate kinase/phosphatase that links receptor-dependent phospholipase C to Ca2+-activated chloride channels

artículo científico publicado en 2008

Identification of a Plasmodium falciparum phospholipid transfer protein

artículo científico publicado en 2013

Identification of a novel cytosolic poly-phosphoinositide-specific phospholipase C (PLC-86) as the major G-protein-regulated enzyme ⬇️

artículo científico publicado el 1 de septiembre de 1991

Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast

artículo científico publicado en 2004

Inositol lipid metabolism in human T lymphocytes activated via the T3 complex

artículo científico publicado en 1987

Insulin uptake across the luminal membrane of the rat proximal tubule in vivo and in vitro.

artículo científico publicado en 2009

Ionomycin stimulates mast cell histamine secretion by forming a lipid-soluble calcium complex ⬇️

artículo científico publicado el 20 de diciembre de 1979

Is phospholipase A2 activation regulated by G-proteins? ⬇️

artículo científico publicado el 1 de abril de 1991

Ligand and membrane-binding behavior of the phosphatidylinositol transfer proteins PITPα and PITPβ.

artículo científico publicado en 2016

Mammalian PITPs at the Golgi and ER-Golgi Membrane Contact Sites

Mammalian phosphatidylinositol transfer proteins: emerging roles in signal transduction and vesicular traffic.

artículo científico publicado en 1999

Measurement of phosphatidylinositol and phosphatidylcholine binding and transfer activity of the lipid transport protein PITP

artículo científico publicado en 2009

Measurement of phospholipase C by monitoring inositol phosphates using [3H]inositol-labeling protocols in permeabilized cells.

artículo científico publicado en 2006

Measurement of phospholipase C by monitoring inositol phosphates using [³H]inositol labeling protocols in permeabilized cells

artículo científico publicado en 2013

Measurement of phospholipase C by monitoring inositol phosphates using [³H]inositol-labeling protocols in permeabilized cells

artículo científico publicado en 2005

Mechanism of ADP ribosylation factor-stimulated phosphatidylinositol 4,5-bisphosphate synthesis in HL60 cells

artículo científico publicado en 2001

Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases

artículo científico publicado en 2006

Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1.

artículo científico publicado en 2017

Monomeric IgE stimulates NFAT translocation into the nucleus, a rise in cytosol Ca2+, degranulation, and membrane ruffling in the cultured rat basophilic leukemia-2H3 mast cell line

artículo científico publicado en 2004

PA binding of phosphatidylinositol 4-phosphate 5-kinase

artículo científico publicado en 2007

Phorbol ester inhibits polyphosphoinositide phosphodiesterase activity stimulated by either Ca2+, fluoride or GTP analogue in HL60 membranes and in permeabilized HL60 cells

artículo científico publicado en 1989

Phorbol esters inhibit inositol phosphate and diacylglycerol formation in proliferating HL60 cells. Relationship to differentiation

artículo científico publicado en 1988

Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases

artículo científico publicado en 2009

Phosphatidylinositol binding of Saccharomyces cerevisiae Pdr16p represents an essential feature of this lipid transfer protein to provide protection against azole antifungals

artículo científico publicado en 2014

Phosphatidylinositol metabolism in mast cells and neutrophils ⬇️

artículo científico publicado el 1 de octubre de 1982

Phosphatidylinositol transfer protein beta displays minimal sphingomyelin transfer activity and is not required for biosynthesis and trafficking of sphingomyelin

artículo científico publicado en 2002

Phosphatidylinositol transfer protein dictates the rate of inositol trisphosphate production by promoting the synthesis of PIP2 ⬇️

artículo científico publicado el 1 de julio de 1995

Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid

scientific journal article

Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis

artículo científico publicado en 2017

Phosphatidylinositol transfer proteins: a requirement in signal transduction and vesicle traffic ⬇️

artículo científico publicado el 1 de mayo de 1998

Phosphatidylinositol transfer proteins: an essential requirement in inositol lipid signalling

artículo científico publicado en 1997

Phosphatidylinositol transfer proteins: requirements in phospholipase C signaling and in regulated exocytosis ⬇️

artículo científico publicado el 23 de junio de 1997

Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum

artículo científico publicado en 2010

Phospholipase D: Regulation by GTPases and protein kinase C and physiological relevance ⬇️

artículo científico publicado el 1 de diciembre de 1996

Phospholipase D: a downstream effector of ARF in granulocytes

artículo científico publicado en 1994

Phospholipid transport protein function at organelle contact sites

article published in 2018

Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes

artículo científico publicado en 2004

Pitpnc1a Regulates Zebrafish Sleep and Wake Behavior through Modulation of Insulin-like Growth Factor Signaling

Plasma-membrane location of phosphatidylinositol hydrolysis in rabbit neutrophils stimulated with formylmethionyl-leucylphenylalanine

artículo científico publicado en 1982

Potential role for phosphatidylinositol transfer protein (PITP) family in lipid transfer during phospholipase C signalling

artículo científico

Potentiation and inhibition of secretion from neutrophils by phorbol ester

artículo científico publicado en 1986

Protein and diacylglycerol phosphorylation in the stimulus-secretion coupling of rat mast cells

artículo científico publicado en 1987

Purification and cloning of phosphatidylinositol transfer proteins from Dictyostelium discoideum: homologues of both mammalian PITPs and Saccharomyces cerevisiae sec14p are found in the same cell

artículo científico publicado en 2000

Purification of phosphatidylinositol transfer protein from brain cytosol for reconstituting G-protein-regulated phosphoinositide-specific phospholipase C-beta isozymes

artículo científico publicado en 1994

RDGBα, a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction

artículo científico publicado en 2015

Rat mast cells permeabilized with ATP secrete histamine in response to calcium ions buffered in the micromolar range

scientific article published on 01 August 1981

Reconstitution System Based on Cytosol-Depleted Cells to Study the Regulation of Phospholipases C and D

artículo científico publicado el 1 de enero de 1998

Reconstitution of GTPγS-Induced NADPH Oxidase Activity in Streptolysin-O-Permeabilized Neutrophils by Specific Cytosol Fractions

scientific article published on 01 November 1999

Reconstitution system based on cytosol-depleted cells to study the regulation of phospholipase D.

artículo científico publicado en 2006

Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons

artículo científico publicado en 2008

Regulation of cytosolic phosphoinositide-phospholipase C by G-protein, Gp.

artículo científico publicado en 1991

Regulation of inositol lipid-specific phospholipase cdelta by changes in Ca2+ ion concentrations

artículo científico publicado en 1997

Requirement for phosphatidylinositol transfer protein in epidermal growth factor signaling

artículo científico publicado en 1995

Resynthesis of phosphatidylinositol in permeabilized neutrophils following phospholipase Cbeta activation: transport of the intermediate, phosphatidic acid, from the plasma membrane to the endoplasmic reticulum for phosphatidylinositol resynthesis i

artículo científico publicado en 1999

Reversible bleb formation in mast cells stimulated with antigen is Ca2+/calmodulin-dependent and bleb size is regulated by ARF6.

artículo científico publicado en 2009

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

artículo científico publicado en 1985

Signalling role for ARF and phospholipase D in mast cell exocytosis stimulated by crosslinking of the high affinity FcepsilonR1 receptor.

artículo científico publicado en 2002

Signalling roles of mammalian phospholipase D1 and D2 ⬇️

artículo científico publicado el 1 de octubre de 2001

Signalling through phospholipase C interferes with clathrin-mediated endocytosis

artículo científico publicado en 2006

Special issue on phospholipase D

artículo científico publicado en 2009

Spermine increases phosphatidylinositol 4,5-bisphosphate content in permeabilized and nonpermeabilized HL60 cells

artículo científico publicado en 2002

Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein

artículo científico publicado en 1985

Stimulus–secretion coupling in rabbit neutrophils is not mediated by phosphatidylinositol breakdown

artículo científico publicado en 1980

Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol

artículo científico publicado en 2004

Subcellular localisation of inositol lipid kinases in rat liver

artículo científico publicado en 1985

The ATP4- receptor of rat mast cells

artículo científico publicado en 1980

The Ca2+-activated polyphosphoinositide phosphodiesterase of human and rabbit neutrophil membranes ⬇️

artículo científico publicado el 15 de julio de 1984

The Concise Guide to PHARMACOLOGY 2013/14: overview

artículo científico publicado en 2013

The Diverse Functions of Phosphatidylinositol Transfer Proteins ⬇️

artículo científico publicado el 1 de enero de 2012

The Drosophila photoreceptor as a model system for studying signalling at membrane contact sites

artículo científico publicado en 2016

The dependence on Ca2+ of phosphatidylinositol breakdown and enzyme secretion in rabbit neutrophils stimulated by formylmethionyl-leucylphenylalanine or ionomycin

artículo científico publicado en 1981

The differentiating agent, retinoic acid, causes an early inhibition of inositol lipid-specific phospholipase C activity in HL-60 cells

artículo científico publicado en 1991

The fatty acid composition of 1,2-diacylglycerol and polyphosphoinositides from human erythrocyte membranes

artículo científico publicado en 1983

The latest phospholipase C, PLCeta, is implicated in neuronal function

artículo científico publicado en 2005

The phosphatidylinositol transfer protein RdgBβ binds 14-3-3 via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein)

scientific article published in 2011

The receptors for ATP and fMetLeuPhe are independently coupled to phospholipases C and A2 via G-protein(s). Relationship between phospholipase C and A2 activation and exocytosis in HL60 cells and human neutrophils

artículo científico publicado en 1989

The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signaling in cytosol-depleted RBL-2H3 and HL-60 cells

artículo científico publicado en 1996

Thyroid-stimulating hormone stimulates increases in inositol phosphates as well as cyclic AMP in the FRTL-5 rat thyroid cell line

artículo científico publicado en 1987

Topological organisation of the phosphatidylinositol 4,5-bisphosphate-phospholipase C resynthesis cycle: PITPs bridge the ER-PM gap.

artículo científico publicado en 2016

Trafficking of phosphatidylinositol by phosphatidylinositol transfer proteins

artículo científico publicado en 2007

Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis

artículo científico publicado en 1987

Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils

artículo científico publicado en 1986

Type I phosphatidylinositol 4-phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the golgi compartment.

artículo científico publicado en 2000

Undifferentiated HL60 cells respond to extracellular ATP and UTP by stimulating phospholipase C activation and exocytosis

artículo científico publicado en 1990

Use of cytochalasin B to distinguish between early and late events in neutrophil activation

artículo científico publicado en 1980

Use of cytosol-depleted HL-60 cells for reconstitution studies of G-protein-regulated phosphoinositide-specific phospholipase C-beta isozymes

artículo científico publicado en 1994

Vesicular transport. Sticky fingers grab a lipid

artículo científico publicado en 1998

Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo.

artículo científico publicado en 1999

f-MetLeuPhe-induced phosphatidylinositol turnover in rabbit neutrophils is dependent on extracellular calcium

scientific article published on 01 January 1980

Lista de obras de Shamshad Cockcroft

14-3-3 protein and ATRAP bind to the soluble class IIB phosphatidylinositol transfer protein RdgBβ at distinct sites.

A modified procedure for thin-layer chromatography of phospholipids

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport.

A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum.

ADP ribosylation factor 1 mutants identify a phospholipase D effector region and reveal that phospholipase D participates in lysosomal secretion but is not sufficient for recruitment of coatomer I.

ADP-ribosylation factor 1-regulated phospholipase D activity is localized at the plasma membrane and intracellular organelles in HL60 cells.

ADP-ribosylation factor and Rho proteins mediate fMLP-dependent activation of phospholipase D in human neutrophils

ADP-ribosylation-factor-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following N-formylmethionyl-leucyl-phenylalanine stimulation of human neutrophils.

ARF and PITP restore GTPγS-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis

ARF-regulated phospholipase D: a potential role in membrane traffic

ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts

ARF1(2-17) does not specifically interact with ARF1-dependent pathways. Inhibition by peptide of phospholipases C beta, D and exocytosis in HL60 cells

ARF1-regulated phospholipase D in human neutrophils is enhanced by PMA and MgATP

ATP induces nucleotide permeability in rat mast cells

ATP stimulates secretion in human neutrophils and HL60 cells via a pertussis toxin-sensitive guanine nucleotide-binding protein coupled to phospholipase C

Activation and inhibition of calcium-dependent histamine secretion by ATP ions applied to rat mast cells ⬇️

Activation of exocytosis by cross-linking of the IgE receptor is dependent on ADP-ribosylation factor 1-regulated phospholipase D in RBL-2H3 mast cells: evidence that the mechanism of activation is via regulation of phosphatidylinositol [...]

Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha.

An essential role for phosphatidylinositol transfer protein in phospholipase C-Mediated inositol lipid signaling

Biochemical and biological functions of class I phosphatidylinositol transfer proteins

Breakdown and synthesis of polyphosphoinositides in fMetLeuPhe-stimulated neutrophils

Bromoenol lactone, an inhibitor of Group V1A calcium-independent phospholipase A2 inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx

Ca2+-dependent conversion of phosphatidylinositol to phosphatidate in neutrophils stimulated with fMet-Leu-Phe or ionophore A23187

Characterization of fMet-Leu-Phe-stimulated phospholipase C in streptolysin-O-permeabilised cells

Chemotactic peptide stimulation of arachidonic acid release in HL60 cells, an interaction between G protein and phospholipase C mediated signal transduction

Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in the formylmethionyl-leucylphenylalanine-dependent production of phosphatidylinositol 3,4,5-trisphosphate in human neutrophils

Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in vitro

Compartmentalized signalling in neurons

Continual production of phosphatidic acid by phospholipase D is essential for antigen-stimulated membrane ruffling in cultured mast cells

Contrasting roles for receptor-stimulated inositol lipid metabolism in secretory cells ⬇️

Correlation between secretion and phospholipase D activation in differentiated HL60 cells.

Crystallization and preliminary X-ray diffraction studies on ADP-ribosylation factor 1

Current thoughts on the phosphatidylinositol transfer protein family

Deletion of 24 amino acids from the C-terminus of phosphatidylinositol transfer protein causes loss of phospholipase C-mediated inositol lipid signalling

Didecanoyl phosphatidylcholine is a superior substrate for assaying mammalian phospholipase D.

Differential control of azurophilic and specific granule exocytosis in Sendai-virus-permeabilized rabbit neutrophils

Differential expression of a C-terminal splice variant of phosphatidylinositol transfer protein beta lacking the constitutive-phosphorylated Ser262 that localizes to the Golgi compartment.

Dual role for guanine nucleotides in stimulus-secretion coupling

Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells

EGF regulation of PITP dynamics is blocked by inhibitors of phospholipase C and of the Ras-MAP kinase pathway

Early events in the activation of Ca2+ dependent secretion: studies with rat peritoneal mast cells

Effect of H-ras proteins on the activity of polyphosphoinositide phospholipase C in HL60 membranes

Endogenous phospholipase D2 localizes to the plasma membrane of RBL-2H3 mast cells and can be distinguished from ADP ribosylation factor-stimulated phospholipase D1 activity by its specific sensitivity to oleic acid

Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells

Evidence for a role of phosphatidylinositol turnover in stimulus–secretion coupling. Studies with rat peritoneal mast cells ⬇️

Fluoxetine elevates allopregnanolone in female rat brain but inhibits a steroid microsomal dehydrogenase rather than activating an aldo-keto reductase.

Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?

Guanine nucleotides stimulate polyphosphoinositide phosphodiesterase and exocytotic secretion from HL60 cells permeabilized with streptolysin O.

Human ITPK1: a reversible inositol phosphate kinase/phosphatase that links receptor-dependent phospholipase C to Ca2+-activated chloride channels

Identification of a Plasmodium falciparum phospholipid transfer protein

Identification of a novel cytosolic poly-phosphoinositide-specific phospholipase C (PLC-86) as the major G-protein-regulated enzyme ⬇️

Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast

Inositol lipid metabolism in human T lymphocytes activated via the T3 complex

Insulin uptake across the luminal membrane of the rat proximal tubule in vivo and in vitro.

Ionomycin stimulates mast cell histamine secretion by forming a lipid-soluble calcium complex ⬇️

Is phospholipase A2 activation regulated by G-proteins? ⬇️

Ligand and membrane-binding behavior of the phosphatidylinositol transfer proteins PITPα and PITPβ.

Mammalian PITPs at the Golgi and ER-Golgi Membrane Contact Sites

Mammalian phosphatidylinositol transfer proteins: emerging roles in signal transduction and vesicular traffic.

Measurement of phosphatidylinositol and phosphatidylcholine binding and transfer activity of the lipid transport protein PITP

Measurement of phospholipase C by monitoring inositol phosphates using [3H]inositol-labeling protocols in permeabilized cells.

Measurement of phospholipase C by monitoring inositol phosphates using [³H]inositol labeling protocols in permeabilized cells

Measurement of phospholipase C by monitoring inositol phosphates using [³H]inositol-labeling protocols in permeabilized cells

Mechanism of ADP ribosylation factor-stimulated phosphatidylinositol 4,5-bisphosphate synthesis in HL60 cells

Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases

Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1.

Monomeric IgE stimulates NFAT translocation into the nucleus, a rise in cytosol Ca2+, degranulation, and membrane ruffling in the cultured rat basophilic leukemia-2H3 mast cell line

PA binding of phosphatidylinositol 4-phosphate 5-kinase

Phorbol ester inhibits polyphosphoinositide phosphodiesterase activity stimulated by either Ca2+, fluoride or GTP analogue in HL60 membranes and in permeabilized HL60 cells

Phorbol esters inhibit inositol phosphate and diacylglycerol formation in proliferating HL60 cells. Relationship to differentiation

Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases

Phosphatidylinositol binding of Saccharomyces cerevisiae Pdr16p represents an essential feature of this lipid transfer protein to provide protection against azole antifungals

Phosphatidylinositol metabolism in mast cells and neutrophils ⬇️

Phosphatidylinositol transfer protein beta displays minimal sphingomyelin transfer activity and is not required for biosynthesis and trafficking of sphingomyelin

Phosphatidylinositol transfer protein dictates the rate of inositol trisphosphate production by promoting the synthesis of PIP2 ⬇️

Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid

Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis

Phosphatidylinositol transfer proteins: a requirement in signal transduction and vesicle traffic ⬇️

Phosphatidylinositol transfer proteins: an essential requirement in inositol lipid signalling