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Lista de obras de Michael Grusch

A bicistronic baculovirus vector for transient and stable protein expression in mammalian cells.

artículo científico publicado en 2008

A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in vitro

artículo científico publicado en 2015

A link between the fibroblast growth factor axis and the miR-16 family reveals potential new treatment combinations in mesothelioma.

artículo científico publicado en 2017

A novel N-hydroxy-N'-aminoguanidine derivative inhibits ribonucleotide reductase activity: Effects in human HL-60 promyelocytic leukemia cells and synergism with arabinofuranosylcytosine (Ara-C).

artículo científico publicado en 2010

Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression

artículo científico publicado en 2016

Activin A is anti-lymphangiogenic in a melanoma mouse model

artículo científico publicado en 2014

Activin A: an emerging target for improving cancer treatment?

scientific article published on 23 July 2020

Activins and follistatins: Emerging roles in liver physiology and cancer

artículo científico publicado en 2009

An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis.

artículo científico publicado en 2012

Analysis of mechanisms contributing to AraC-mediated chemoresistance and re-establishment of drug sensitivity by the novel heterodinucleoside phosphate 5-FdUrd-araC.

artículo científico publicado en 2006

Angioregulatory microRNAs in Colorectal Cancer

scientific article published on 26 December 2019

Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells.

artículo científico publicado en 2008

Apelin promotes lymphangiogenesis and lymph node metastasis.

artículo científico publicado en 2014

Apoptosis-inducing cleavage of caspases by trimidox, an inhibitor of ribonucleotide reductase

artículo científico publicado en 2000

Avemar, a nontoxic fermented wheat germ extract, attenuates the growth of sensitive and 5-FdUrd/Ara-C cross-resistant H9 human lymphoma cells through induction of apoptosis.

artículo científico publicado en 2009

Avemar, a nontoxic fermented wheat germ extract, induces apoptosis and inhibits ribonucleotide reductase in human HL-60 promyelocytic leukemia cells

Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis

artículo científico publicado en 2018

Benzamide riboside induces apoptosis independent of Cdc25A expression in human ovarian carcinoma N.1 cells

artículo científico publicado en 1999

Berberine and a Berberis lycium extract inactivate Cdc25A and induce alpha-tubulin acetylation that correlate with HL-60 cell cycle inhibition and apoptosis

artículo científico publicado en 2010

Bimodal expression of Sprouty2 during the cell cycle is mediated by phase-specific Ras/MAPK and c-Cbl activities

artículo científico publicado en 2010

Biochemical effects of piceatannol in human HL-60 promyelocytic leukemia cells--synergism with Ara-C.

artículo científico publicado en 2008

CDC25A Mediates Survival by Activating AKT Kinase

scientific article published on 12 October 2001

Canine and human sarcomas exhibit predominant FGFR1 expression and impaired viability after inhibition of signaling.

artículo científico publicado en 2014

Cdc25A phosphatase suppresses apoptosis induced by serum deprivation

artículo científico publicado en 2001

Cell characterization by proteome profiling applied to primary hepatocytes and hepatocyte cell lines Hep-G2 and Hep-3B.

artículo científico publicado en 2010

Circulating activin A is a novel prognostic biomarker in malignant pleural mesothelioma - A multi-institutional study.

artículo científico publicado en 2016

Circulating complement component 4d (C4d) correlates with tumor volume, chemotherapeutic response and survival in patients with malignant pleural mesothelioma.

artículo científico publicado en 2017

Circulating fibrinogen is a prognostic and predictive biomarker in malignant pleural mesothelioma

scientific article published on 16 January 2014

Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis

artículo científico publicado en 1999

Cytotoxic and apoptotic effects of novel heterodinucleoside phosphates consisting of 5-fluorodeoxyuridine and Ara-C in human cancer cell lines

artículo científico publicado en 2004

Cytotoxic and biochemical effects of 3,3′,4,4′,5,5′-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells

artículo científico publicado en 2006

Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells.

artículo científico publicado en 2005

DNA Methylation as a Noninvasive Epigenetic Biomarker for the Detection of Cancer

artículo científico publicado en 2017

Deregulation of the activin/follistatin system in hepatocarcinogenesis

artículo científico publicado en 2006

Differential effects of polymorphic alleles of FGF receptor 4 on colon cancer growth and metastasis

artículo científico publicado en 2012

Digalloylresveratrol, a new phenolic acid derivative induces apoptosis and cell cycle arrest in human HT-29 colon cancer cells

artículo científico publicado en 2008

Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells.

artículo científico publicado en 2013

Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma.

artículo científico publicado en 2015

EGCG-meditated cyto- and genotoxicity in HaCat keratinocytes is impaired by cell-mediated clearance of auto-oxidation-derived H2O2: an algorithm for experimental setting correction

artículo científico publicado en 2011

Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers

artículo científico publicado en 2012

Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver

artículo científico publicado en 2007

Effects of heavy water (D2O) on human pancreatic tumor cells.

artículo científico publicado en 2005

Epigallocatechin gallate, ellagic acid, and rosmarinic acid perturb dNTP pools and inhibit de novo DNA synthesis and proliferation of human HL-60 promyelocytic leukemia cells: Synergism with arabinofuranosylcytosine.

artículo científico publicado en 2014

Epigenetic Biomarkers in Cancer.

artículo científico publicado en 2018

Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.

artículo científico publicado en 2015

Erythropoietin receptor expression is a potential prognostic factor in human lung adenocarcinoma

artículo científico publicado en 2013

Expression of FGFR1-4 in Malignant Pleural Mesothelioma Tissue and Corresponding Cell Lines and its Relationship to Patient Survival and FGFR Inhibitor Sensitivity

artículo científico publicado en 2019

Expression of activins C and E induces apoptosis in human and rat hepatoma cells.

artículo científico publicado en 2003

FGF18 in colorectal tumour cells: autocrine and paracrine effects

artículo científico publicado en 2007

FGF2 and EGF induce epithelial-mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal.

artículo científico publicado en 2018

FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities

artículo científico publicado en 2008

FGF5 is expressed in melanoma and enhances malignancy in vitro and in vivo.

artículo científico publicado en 2017

FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer

scientific article published on 01 October 2018

Fas ligand is expressed in normal breast epithelial cells and is frequently up-regulated in breast cancer

artículo científico publicado en 2000

Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.

artículo científico publicado en 2014

Fibroblast growth factor receptor 3 isoforms: Novel therapeutic targets for hepatocellular carcinoma?

artículo científico publicado en 2015

Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration.

artículo científico publicado en 2010

Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer

artículo científico publicado en 2016

Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.

artículo científico publicado en 2014

Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.

artículo científico publicado en 2014

Fibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition

artículo científico publicado en 2011

Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis

artículo científico publicado en 2015

Fine structural correlates of sensitivity in the eyes of the ctenid spider, Cupiennius salei Keys

artículo científico publicado en 1997

Gallic acid inhibits ribonucleotide reductase and cyclooxygenases in human HL-60 promyelocytic leukemia cells.

artículo científico publicado en 2006

Gallic acid, a common dietary phenolic protects against high fat diet induced DNA damage

scientific article published on 23 July 2018

HB-EGF is a paracrine growth stimulator for early tumor prestages in inflammation-associated hepatocarcinogenesis.

artículo científico publicado en 2008

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma.

artículo científico publicado en 2016

Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca2+ Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK.

artículo científico publicado en 2017

Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes

artículo científico publicado en 2010

In vitro and in vivo antitumor activity of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine.

artículo científico publicado en 2004

In vitro anti-cancer activity of two ethno-pharmacological healing plants from Guatemala Pluchea odorata and Phlebodium decumanum

artículo científico publicado en 2009

In vitro anti-inflammatory and anticancer activities of extracts of Acalypha alopecuroidea (Euphorbiaceae).

artículo científico publicado en 2009

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.

artículo científico publicado en 2013

In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen.

artículo científico publicado en 2013

Indications for cell stress in response to adenoviral and baculoviral gene transfer observed by proteome profiling of human cancer cells.

artículo científico publicado en 2010

Inhibin/activin expression in human and rodent liver: subunits α and βB as new players in human hepatocellular carcinoma?

artículo científico publicado en 2011

Inhibition of tumour spheroid-induced prometastatic intravasation gates in the lymph endothelial cell barrier by carbamazepine: drug testing in a 3D model

artículo científico publicado en 2013

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells

artículo científico publicado en 2009

Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer.

artículo científico publicado en 2017

Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis

artículo científico publicado en 2017

Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?

artículo científico publicado en 2014

Ki67 index is an independent prognostic factor in epithelioid but not in non-epithelioid malignant pleural mesothelioma: a multicenter study

artículo científico publicado en 2015

Light-assisted small-molecule screening against protein kinases.

artículo científico publicado en 2015

Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation.

artículo científico publicado en 2014

Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma: Increased Cell Migration and Its Association with EGFR Expression

artículo científico publicado en 2019

Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements.

artículo científico publicado en 2017

Loss of CUL4A expression is underlying cisplatin hypersensitivity in colorectal carcinoma cells with acquired trabectedin resistance

artículo científico publicado en 2017

Lysosomal Sequestration Impairs the Activity of the Preclinical FGFR Inhibitor PD173074

Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside

artículo científico publicado en 2002

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis

artículo científico publicado en 2013

Microscopic analysis of adenoviral decontamination using GFP adenovirus with comparable sensitivity to flow cytometry.

artículo científico publicado en 2009

Monitoring viral decontamination procedures with green fluorescent protein-expressing adenovirus.

artículo científico publicado en 2006

Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro

artículo científico publicado en 2010

N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine.

artículo científico publicado en 2007

NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells

artículo científico publicado en 2011

NORE1B is a putative tumor suppressor in hepatocarcinogenesis and may act via RASSF1A.

artículo científico publicado en 2009

Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo

scientific article published on 03 May 2018

Non-parenchymal liver cells support the growth advantage in the first stages of hepatocarcinogenesis

artículo científico publicado en 2005

Novel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells: inhibition of ribonucleotide reductase activity.

artículo científico publicado en 2008

Novel resveratrol derivatives induce apoptosis and cause cell cycle arrest in prostate cancer cell lines.

artículo científico publicado en 2007

P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b

artículo científico publicado en 2020

Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells.

artículo científico publicado en 2018

Photodynamic action of meta-tetrahydroxyphenylchlorin (mTHPC) on an ovarian cancer cell line.

artículo científico publicado en 2000

Pretreatment serum C-reactive protein levels predict benefit from multimodality treatment including radical surgery in malignant pleural mesothelioma: a retrospective multicenter analysis

artículo científico publicado en 2012

Pro- and anticarcinogenic mechanisms of piceatannol are activated dose dependently in MCF-7 breast cancer cells.

artículo científico publicado en 2009

Prostaglandin E(2) stimulates progression-related gene expression in early colorectal adenoma cells.

artículo científico publicado en 2006

Response of experimental malignant melanoma models to the pan-Aurora kinase inhibitor VE-465.

artículo científico publicado en 2010

Sensitivity of Melanoma Cells to EGFR and FGFR Activation but Not Inhibition is Influenced by Oncogenic BRAF and NRAS Mutations.

artículo científico publicado en 2015

Shifting the Immune-Suppressive to Predominant Immune-Stimulatory Radiation Effects by SBRT-PArtial Tumor Irradiation Targeting HYpoxic Segment (SBRT-PATHY)

artículo científico publicado en 2020

Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.

artículo científico publicado en 2014

Stable protein expression in mammalian cells using baculoviruses.

artículo científico publicado en 2012

Subcellular localisation of Cdc25A determines cell fate

artículo científico publicado en 2004

Subtype-specific KRAS mutations in advanced lung adenocarcinoma: a retrospective study of patients treated with platinum-based chemotherapy.

artículo científico publicado en 2014

Synergistic effects of deuterium oxide and gemcitabine in human pancreatic cancer cell lines

artículo científico publicado en 2007

Synergistic effects of erlotinib and everolimus on bronchial carcinoids and large-cell neuroendocrine carcinomas with activated EGFR/AKT/mTOR pathway

artículo científico publicado en 2012

TNFalpha-mediated cell death is independent of cdc25A

artículo científico publicado en 1998

Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.

artículo científico publicado en 2011

Telomerase reverse transcriptase promoter mutations identify a genomically defined and highly aggressive human pleural mesothelioma subgroup

artículo científico publicado en 2020

Temsirolimus inhibits malignant pleural mesothelioma growth in vitro and in vivo: synergism with chemotherapy

artículo científico publicado en 2011

The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells.

artículo científico publicado en 2010

The activin axis in liver biology and disease.

artículo científico publicado en 2006

The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis

artículo científico publicado en 2012

The effect of organic anion-transporting polypeptides 1B1, 1B3 and 2B1 on the antitumor activity of flavopiridol in breast cancer cells.

artículo científico publicado en 2014

The germacranolide sesquiterpene lactone neurolenin B of the medicinal plant Neurolaena lobata (L.) R.Br. ex Cass inhibits NPM/ALK-driven cell expansion and NF-κB-driven tumour intravasation

artículo científico publicado en 2015

The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells

artículo científico publicado en 2012

The optogenetic promise for oncology: Episode I.

artículo científico publicado en 2014

The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.

artículo científico publicado en 2016

The thiosemicarbazone MeNNMe induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

artículo científico publicado en 2018

Trabectedin Is Active against Malignant Pleural Mesothelioma Cell and Xenograft Models and Synergizes with Chemotherapy and Bcl-2 Inhibition In Vitro

artículo científico publicado en 2016

Transferrin Ensures Survival of Ovarian Carcinoma Cells Subjected to Deferoxamine, TNFA, FASL, Trail or MYC-Activation

scientific article published on 12 May 2001

Transferrin ensures survival of ovarian carcinoma cells when apoptosis is induced by TNFalpha, FasL, TRAIL, or Myc.

artículo científico publicado en 2003

Trimidox, an inhibitor of ribonucleotide reductase, induces apoptosis and activates caspases in HL-60 promyelocytic leukemia cells

article

Trimidox, an inhibitor of ribonucleotide reductase, synergistically enhances the inhibition of colony formation by Ara-C in HL-60 human promyelocytic leukemia cells

artículo científico publicado en 2002

Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis.

artículo científico publicado en 2011

Use of four new human-derived liver-cell lines for the detection of genotoxic compounds in the single-cell gel electrophoresis (SCGE) assay.

artículo científico publicado en 2008

Vaults and the major vault protein: novel roles in signal pathway regulation and immunity

artículo científico publicado en 2009

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis

artículo científico publicado en 2013

YB-1 Knockdown Inhibits the Proliferation of Mesothelioma Cells through Multiple Mechanisms

artículo científico publicado en 2020