Lista de obras - Karl J Tronstad - Dominio Público Uruguay

A Bioactively Modified Fatty Acid Improves Survival and Impairs Metastasis in Preclinical Models of Acute Leukemia

artículo científico publicado en 2006

A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology

artículo científico publicado en 2015

Antiproliferative effects of a non-beta-oxidizable fatty acid, tetradecylthioacetic acid, in native human acute myelogenous leukemia blast cultures

artículo científico publicado en 2002

Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?

artículo científico publicado en 2005

Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties

artículo científico publicado en 2014

Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model ⬇️

artículo científico publicado en 2021

BMET-34DRUG REPURPOSING DISCOVERS BETA-SITOSTEROL AS AN EFFECTIVE THERAPEUTIC AGENT AGAINST MELANOMA BRAIN METASTASES IN VIVO.

artículo científico publicado en 2015

Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines

artículo científico publicado en 2009

Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression: evidence for peroxisome proliferator-activated rec

artículo científico publicado en 2003

Connexin-based signaling in acute myelogenous leukemia (AML).

artículo científico publicado en 2009

Corrigendum: A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology

artículo científico publicado en 2016

Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.

artículo científico publicado en 2019

Far-infrared radiation protects viability in a cell model of Spinocerebellar Ataxia by preventing polyQ protein accumulation and improving mitochondrial function

artículo científico publicado en 2016

Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status

artículo científico publicado en 2001

Human TNF-alpha in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes

artículo científico publicado en 2002

Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma

artículo científico publicado en 2009

Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model

artículo científico publicado en 2009

Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation

artículo científico publicado en 2003

In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.

artículo científico publicado en 1999

In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum

artículo científico publicado en 2005

Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats.

artículo científico publicado en 2017

Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA)

artículo científico publicado en 2012

Introducing nano-scale quantitative polymerase chain reaction

artículo científico publicado en 2018

Is targeted chemotherapy an alternative to immunotherapy in chronic lymphocytic leukemia?

artículo científico publicado en 2005

Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats

artículo científico publicado en 2008

Metabolic effects of 3-thia fatty acid in cancer cells

scientific article published on 01 January 1999

Metabolic effects of thia fatty acids

artículo científico publicado en 2002

Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells

artículo científico publicado en 2021

Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells

artículo científico publicado en 2003

Modified fatty acids and their possible therapeutic targets in malignant diseases ⬇️

artículo científico publicado el 1 de octubre de 2003

Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality

artículo científico publicado en 2019

Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth

artículo científico publicado en 2001

Peptide-mediated delivery of donor mitochondria improves mitochondrial function and cell viability in human cybrid cells with the MELAS A3243G mutation

artículo científico publicado en 2017

Poorly oxidizable fatty acid analogues inhibit the proliferation of cancer cells in culture

artículo científico publicado en 1999

Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB.

artículo científico publicado en 2009

Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML.

artículo científico publicado en 2006

Regulation and quantification of cellular mitochondrial morphology and content.

artículo científico publicado en 2014

Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells.

artículo científico publicado en 2015

Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling

artículo científico publicado en 2007

Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways

artículo científico publicado en 2001

Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance.

artículo científico publicado en 2002

The angiogenic switch leads to a metabolic shift in human glioblastoma

artículo científico publicado en 2016

The metabolic syndrome and the hepatic fatty acid drainage hypothesis.

artículo científico publicado en 2005

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide

artículo científico publicado en 2018

Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation

artículo científico publicado en 2019

Lista de obras de Karl J Tronstad

A Bioactively Modified Fatty Acid Improves Survival and Impairs Metastasis in Preclinical Models of Acute Leukemia

A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology

Antiproliferative effects of a non-beta-oxidizable fatty acid, tetradecylthioacetic acid, in native human acute myelogenous leukemia blast cultures

Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?

Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties

Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model ⬇️

BMET-34DRUG REPURPOSING DISCOVERS BETA-SITOSTEROL AS AN EFFECTIVE THERAPEUTIC AGENT AGAINST MELANOMA BRAIN METASTASES IN VIVO.

Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines

Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression: evidence for peroxisome proliferator-activated rec

Connexin-based signaling in acute myelogenous leukemia (AML).

Corrigendum: A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology

Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.

Far-infrared radiation protects viability in a cell model of Spinocerebellar Ataxia by preventing polyQ protein accumulation and improving mitochondrial function

Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status

Human TNF-alpha in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes

Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma

Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model

Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation

In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.

In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum

Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats.

Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA)

Introducing nano-scale quantitative polymerase chain reaction

Is targeted chemotherapy an alternative to immunotherapy in chronic lymphocytic leukemia?

Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats

Metabolic effects of 3-thia fatty acid in cancer cells

Metabolic effects of thia fatty acids

Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells

Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells

Modified fatty acids and their possible therapeutic targets in malignant diseases ⬇️

Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality

Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth

Peptide-mediated delivery of donor mitochondria improves mitochondrial function and cell viability in human cybrid cells with the MELAS A3243G mutation

Poorly oxidizable fatty acid analogues inhibit the proliferation of cancer cells in culture

Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB.

Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML.

Regulation and quantification of cellular mitochondrial morphology and content.

Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells.

Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling

Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways

Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance.

The angiogenic switch leads to a metabolic shift in human glioblastoma

The metabolic syndrome and the hepatic fatty acid drainage hypothesis.

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide

Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation