Lista de obras - Jari Yli-Kauhaluoma - Dominio Público Uruguay

(+)-Dehydroabietic acid, an abietane-type diterpene, inhibits Staphylococcus aureus biofilms in vitro

artículo científico publicado en 2013

A Developability-Focused Optimization Approach Allows Identification of in Vivo Fast-Acting Antimalarials: N-[3-[(Benzimidazol-2-yl)amino]propyl]amides.

artículo científico publicado en 2015

A modification of the Hammett equation for predicting ionisation constants of p-vinyl phenols.

artículo científico publicado en 2005

A new insight into solid-state conformation of macrolide antibiotics

artículo científico publicado en 2007

Abietane-Type Diterpenoid Amides with Highly Potent and Selective Activity against Leishmania donovani and Trypanosoma cruzi.

artículo científico publicado en 2016

Acetylcholinesterase inhibitory guided fractionation of Melissa officinalis L.

artículo científico publicado en 2008

Adenosine analogs bearing phosphate isosteres as human MDO1 ligands

artículo científico publicado en 2018

Albumin stimulates the activity of the human UDP-glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the effects are enzyme and substrate dependent

artículo científico publicado en 2013

Analysis of small molecules by ultra thin-layer chromatography-atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry.

artículo científico publicado en 2005

Anti-leishmanial activity of betulin derivatives

artículo científico publicado en 2010

Antibacterial profiling of abietane-type diterpenoids.

artículo científico publicado en 2016

Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.

artículo científico publicado en 2006

Antiprotozoal activity of dehydroabietic acid derivatives against Leishmania donovani and Trypanosoma cruzi

Assessing the data quality in predictive toxicology using a panel of cell lines and cytotoxicity assays

artículo científico publicado en 2006

Asymmetry in catalysis by membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor

artículo científico publicado en 2019

Azulene-based compounds for targeting orexin receptors

artículo científico publicado en 2018

Benzo[cd]azulene skeleton: azulene, heptafulvene, and tropone derivatives.

artículo científico publicado en 2009

Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo.

artículo científico publicado en 2016

Betulin derivatives impair Leishmania braziliensis viability and host-parasite interaction

artículo científico publicado en 2014

Betulin-derived compounds as inhibitors of alphavirus replication

artículo científico publicado en 2009

Biosynthesis of the Bis-Prenylated Alkaloids Muscoride A and B

scientific article published on 19 November 2019

Biotransformation of Cyclodextrine-Complexed Semisynthetic Betulin Derivatives by Plant Cells.

artículo científico publicado en 2018

Bovine serum albumin decreases Km values of human UDP-glucuronosyltransferases 1A9 and 2B7 and increases Vmax values of UGT1A9.

artículo científico publicado en 2011

Brain-derived neurotrophic factor controls activity-dependent maturation of CA1 synapses by downregulating tonic activation of presynaptic kainate receptors.

artículo científico publicado en 2009

C1 Domain-targeted isophthalate derivatives induce cell elongation and cell cycle arrest in HeLa cells

artículo científico publicado en 2011

C1 domain-targeted isophthalates as protein kinase C modulators: structure-based design, structure-activity relationships and biological activities

artículo científico publicado en 2014

Catalytic antibodies: the rerouting of chemical reactions. Towards electrophilic aromatic substitution by carbon dioxide

scientific article published on 01 October 1996

Catalytic, Tunable, One-Step Bismuth(III) Triflate Reaction with Alcohols: Dehydration Versus Dimerization

artículo científico publicado en 2018

Chemical profiles of birch and alder bark by ambient mass spectrometry

artículo científico publicado en 2019

Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17

scientific article published on 01 April 2006

Combined Effect of Naturally-Derived Biofilm Inhibitors and Differentiated HL-60 Cells in the Prevention of Staphylococcus aureus Biofilm Formation

artículo científico publicado en 2020

Conditioned Reward of Opioids, but not Psychostimulants, is Impaired in GABA-A Receptor δ Subunit Knockout Mice

scientific article published on 09 July 2018

Conformation study of 2-arylbenzimidazoles as inhibitors of Chlamydia pneumoniae growth.

artículo científico publicado en 2012

Current status and future prospects of C1 domain ligands as drug candidates

artículo científico publicado en 2011

Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1

artículo científico publicado en 2018

Design and synthesis of 2-arylbenzimidazoles and evaluation of their inhibitory effect against Chlamydia pneumoniae

artículo científico publicado en 2010

Design, synthesis, and biological activity of isophthalic acid derivatives targeted to the C1 domain of protein kinase C.

artículo científico publicado en 2009

Design, synthesis, and biological activity of urea derivatives as anaplastic lymphoma kinase inhibitors.

artículo científico publicado en 2011

Determination of neutral carbohydrates by CZE with direct UV detection

artículo científico publicado en 2007

Discovery of 12-Thiazole Abietanes as Selective Inhibitors of the Human Metabolic Serine Hydrolase hABHD16A

artículo científico publicado en 2018

Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12)

artículo científico publicado en 2014

Electrospray ionization mass spectrometry and tandem mass spectrometry of clodronate and related bisphosphonate and phosphonate compounds

artículo científico publicado en 2002

Eudismic analysis of tricyclic sesquiterpenoid alcohols: lead structures for the design of potent inhibitors of the human UDP-glucuronosyltransferase 2B7

artículo científico publicado en 2007

Exploring marine resources for bioactive compounds.

artículo científico publicado en 2014

Exploring the scope of the 29G12 antibody catalyzed 1,3-dipolar cycloaddition reaction

artículo científico publicado en 2005

Functionalization of carboxylated lignin nanoparticles for targeted and pH-responsive delivery of anticancer drugs

artículo científico publicado en 2017

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases

artículo científico publicado en 2009

HIV-1 Tat-peptide inhibits protein kinase C and protein kinase A through substrate competition

artículo científico publicado en 2010

Identification of free and conjugated metabolites of mesocarb in human urine by LC-MS/MS.

artículo científico publicado en 2010

Inhibitory effect of the natural product betulin and its derivatives against the intracellular bacterium Chlamydia pneumoniae.

artículo científico publicado en 2010

Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma

artículo científico publicado en 2013

In vitro evaluation of biodegradable lignin-based nanoparticles for drug delivery and enhanced antiproliferation effect in cancer cells

artículo científico publicado en 2017

Isoform-selective inhibition of the human UDP-glucuronosyltransferase 2B7 by isolongifolol derivatives

scientific article published on 03 May 2007

Ketamine-induced regulation of TrkB-GSK3β signaling is accompanied by slow EEG oscillations and sedation but is independent of hydroxynorketamine metabolites

scientific article published on 25 June 2019

Mass-tag enhanced immuno-laser desorption/ionization mass spectrometry for sensitive detection of intact protein antigens.

artículo científico publicado en 2015

Mechanism of the Oxidation of Heptafulvenes to Tropones Studied by Online Mass Spectrometry and Density Functional Theory Calculations

scientific article published on 21 October 2019

Methadone increases intracellular calcium in SH-SY5Y and SH-EP1-halpha7 cells by activating neuronal nicotinic acetylcholine receptors

artículo científico publicado en 2005

Microplate screening assay for binding of ligands to bovine or reindeer beta-lactoglobulins

artículo científico publicado en 2006

Microwave-assisted synthesis of imidazoles: reaction of p-toluenesulfonylmethyl isocyanide and polymer-bound imines

artículo científico publicado en 2005

Morphine, Oxycodone, Methadone and Its Enantiomers in Different Models of Nociception in the Rat

article

Natural Stilbenoids Have Anti-Inflammatory Properties in Vivo and Down-Regulate the Production of Inflammatory Mediators NO, IL6, and MCP1 Possibly in a PI3K/Akt-Dependent Manner

artículo científico publicado en 2018

New derivatives of dehydroabietic acid target planktonic and biofilm bacteria in Staphylococcus aureus and effectively disrupt bacterial membrane integrity

artículo científico publicado en 2015

Nucleophilic Substitution of Hydrogen Facilitated by Quinone Methide Moieties in Benzo[cd]azulen-3-ones

artículo científico publicado en 2017

On the hydrolytic behavior of tinidazole, metronidazole, and ornidazole

artículo científico publicado en 2003

Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development

artículo científico publicado en 2015

Optimization of a High-Throughput 384-Well Plate-Based Screening Platform with Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 15442 Biofilms

artículo científico publicado en 2020

Pharmacological characterization of noroxymorphone as a new opioid for spinal analgesia

artículo científico publicado en 2008

Pharmacological properties of the ubiquitous natural product betulin

artículo científico publicado en 2006

Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

artículo científico publicado en 2015

Polyketide derivatives active against Botrytis cinerea in Gerbera hybrida.

artículo científico publicado en 2010

Potent inhibitors of the human UDP-glucuronosyltransferase 2B7 derived from the sesquiterpenoid alcohol longifolol

scientific article published on 01 June 2007

Preparation and Characterization of Dentin Phosphophoryn-Derived Peptide-Functionalized Lignin Nanoparticles for Enhanced Cellular Uptake

artículo científico publicado en 2019

Protein kinases as drug targets.

artículo científico publicado en 2011

Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo

scientific article published on 29 April 2019

Quercetin-Based Modified Porous Silicon Nanoparticles for Enhanced Inhibition of Doxorubicin-Resistant Cancer Cells

artículo científico publicado en 2016

Recent advances in 1,3-dipolar cycloaddition reactions on solid supports

artículo científico publicado en 2005

Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation

scientific article published on 10 May 2007

Rigorous computational study reveals what docking overlooks: Double trouble from membrane association in protein kinase C modulators

scientific article published on 11 September 2020

Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C.

artículo científico publicado en 2018

Screening and characterisation of antimicrobial properties of semisynthetic betulin derivatives

artículo científico publicado en 2014

Screening of FDA-Approved Drugs Using a 384-Well Plate-Based Biofilm Platform: The Case of Fingolimod

artículo científico publicado en 2020

Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids

artículo científico publicado en 2020

Simple 3D printed stainless steel microreactors for online mass spectrometric analysis

scientific article published on 02 July 2019

Solid-Phase Synthesis of Pyrazolopyridines from Polymer-Bound Alkyne and Azomethine Imines

artículo científico publicado en 2006

Solid-phase synthesis of 1,2,3-triazoles via 1,3-dipolar cycloaddition

artículo científico publicado en 2003

Solid-phase synthesis of amino acid derived N-unsubstituted pyrazoles via sydnones

artículo científico publicado en 2009

Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds

scientific article published on 09 July 2018

Stereochemical and steric control of the UDP-glucuronosyltransferase-catalyzed conjugation reaction: a rational approach for the design of inhibitors for the human UGT2B7.

artículo científico publicado en 2007

Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17

artículo científico publicado en 2006

Stereoselective aza Diels-Alder reaction on solid phase: a facile synthesis of hexahydrocinnoline derivatives

artículo científico publicado en 2007

Strategies to Prevent Biofilm Infections on Biomaterials: Effect of Novel Naturally-Derived Biofilm Inhibitors on a Competitive Colonization Model of Titanium by Staphylococcus aureus and SaOS-2 Cells

scientific article published on 29 February 2020

Structural Isosteres of Phosphate Groups in the Protein Data Bank

artículo científico publicado en 2017

Structure-Activity Relationships of 1-Benzoylazulenes at the OX1 and OX2 Orexin Receptors

artículo científico publicado en 2019

Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence

artículo científico publicado en 2021

Synthesis and Anti-Proliferative Activity of Sulfanyltriazolylnaphthalenols and Sulfanyltriazolylnaphthalene-1,4-diones.

artículo científico publicado en 2016

Synthesis and Antiproliferative Activity of Marine Bromotyrosine Purpurealidin I and Its Derivatives

Synthesis and Biological Evaluation of 2-Aminobenzothiazole and Benzimidazole Analogs Based on the Clathrodin Structure

artículo científico publicado en 2015

Synthesis and anti-leishmanial activity of heterocyclic betulin derivatives

artículo científico publicado en 2010

Synthesis and biological evaluation of 2-arylbenzimidazoles targeting Leishmania donovani

artículo científico publicado en 2015

Synthesis and biological evaluation of new oxadiazoline-substituted naphthalenyl acetates as anticancer agents

artículo científico publicado en 2014

Synthesis and characterization of hydroxylated mesocarb metabolites for doping control

artículo científico publicado en 2009

Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease

artículo científico publicado en 2011

Synthesis and tautomerization of benzo[cd]azulen-3-ones

artículo científico publicado en 2011

Synthesis of 1,3,6-Trisubstituted Azulenes

scientific article published on 11 November 2015

Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors

artículo científico publicado en 2018

Synthesis of aminophosphonate haptens for an aminoacylation reaction between methyl glucoside and a beta-alanyl ester

scientific article published on 01 August 2000

Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel KV10.1.

artículo científico publicado en 2017

Synthesis, Identification, and Structure-Activity Relationship Analysis of GATA4 and NKX2-5 Protein-Protein Interaction Modulators

artículo científico publicado en 2019

Synthesis, structure characterization, and enzyme screening of clenbuterol glucuronides.

artículo científico publicado en 2009

The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells

artículo científico publicado en 2013

The Diels-Alder reaction between deactivated dienes and electron-deficient dienophiles on solid support: stereoselective synthesis of hexahydro-1,3-dioxoisoindoles

artículo científico publicado en 2004

The binding of synthetic retinoids to lipocalin beta-lactoglobulins

artículo científico publicado en 2010

Tissue-specific study across the stem reveals the chemistry and transcriptome dynamics of birch bark

scientific article published on 07 March 2019

Total synthesis of bistramide A and its 36(Z) isomers: differential effect on cell division, differentiation, and apoptosis

artículo científico publicado en 2012

Toxicity of betulin derivatives and in vitro effect on promastigotes and amastigotes of Leishmania infantum and L. donovani

artículo científico publicado en 2011

Tricyclic Benzo[cd]azulenes selectively inhibit activities of Pim kinases and restrict growth of Epstein-Barr virus-transformed cells

artículo científico publicado en 2013

Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents.

artículo científico publicado en 2017

Twisted alpha-keto amides as transition-state analogues for acyl-transfer reactions: synthesis of the immunoconjugates

artículo científico publicado en 1994

UDP-glucuronic acid binds first and the aglycone substrate binds second to form a ternary complex in UGT1A9-catalyzed reactions, in both the presence and absence of bovine serum albumin

artículo científico publicado en 2012

UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly

artículo científico publicado en 2008

Utilization of in situ ELISA method for examining Trk receptor phosphorylation in cultured cells

artículo científico publicado en 2013

Lista de obras de Jari Yli-Kauhaluoma

(+)-Dehydroabietic acid, an abietane-type diterpene, inhibits Staphylococcus aureus biofilms in vitro

A Developability-Focused Optimization Approach Allows Identification of in Vivo Fast-Acting Antimalarials: N-[3-[(Benzimidazol-2-yl)amino]propyl]amides.

A modification of the Hammett equation for predicting ionisation constants of p-vinyl phenols.

A new insight into solid-state conformation of macrolide antibiotics

Abietane-Type Diterpenoid Amides with Highly Potent and Selective Activity against Leishmania donovani and Trypanosoma cruzi.

Acetylcholinesterase inhibitory guided fractionation of Melissa officinalis L.

Adenosine analogs bearing phosphate isosteres as human MDO1 ligands

Albumin stimulates the activity of the human UDP-glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the effects are enzyme and substrate dependent

Analysis of small molecules by ultra thin-layer chromatography-atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry.

Anti-leishmanial activity of betulin derivatives

Antibacterial profiling of abietane-type diterpenoids.

Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.

Antiprotozoal activity of dehydroabietic acid derivatives against Leishmania donovani and Trypanosoma cruzi

Assessing the data quality in predictive toxicology using a panel of cell lines and cytotoxicity assays

Asymmetry in catalysis by membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor

Azulene-based compounds for targeting orexin receptors

Benzo[cd]azulene skeleton: azulene, heptafulvene, and tropone derivatives.

Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo.

Betulin derivatives impair Leishmania braziliensis viability and host-parasite interaction

Betulin-derived compounds as inhibitors of alphavirus replication

Biosynthesis of the Bis-Prenylated Alkaloids Muscoride A and B

Biotransformation of Cyclodextrine-Complexed Semisynthetic Betulin Derivatives by Plant Cells.

Bovine serum albumin decreases Km values of human UDP-glucuronosyltransferases 1A9 and 2B7 and increases Vmax values of UGT1A9.

Brain-derived neurotrophic factor controls activity-dependent maturation of CA1 synapses by downregulating tonic activation of presynaptic kainate receptors.

C1 Domain-targeted isophthalate derivatives induce cell elongation and cell cycle arrest in HeLa cells

C1 domain-targeted isophthalates as protein kinase C modulators: structure-based design, structure-activity relationships and biological activities

Catalytic antibodies: the rerouting of chemical reactions. Towards electrophilic aromatic substitution by carbon dioxide

Catalytic, Tunable, One-Step Bismuth(III) Triflate Reaction with Alcohols: Dehydration Versus Dimerization

Chemical profiles of birch and alder bark by ambient mass spectrometry

Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17

Combined Effect of Naturally-Derived Biofilm Inhibitors and Differentiated HL-60 Cells in the Prevention of Staphylococcus aureus Biofilm Formation

Conditioned Reward of Opioids, but not Psychostimulants, is Impaired in GABA-A Receptor δ Subunit Knockout Mice

Conformation study of 2-arylbenzimidazoles as inhibitors of Chlamydia pneumoniae growth.

Current status and future prospects of C1 domain ligands as drug candidates

Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1

Design and synthesis of 2-arylbenzimidazoles and evaluation of their inhibitory effect against Chlamydia pneumoniae

Design, synthesis, and biological activity of isophthalic acid derivatives targeted to the C1 domain of protein kinase C.

Design, synthesis, and biological activity of urea derivatives as anaplastic lymphoma kinase inhibitors.

Determination of neutral carbohydrates by CZE with direct UV detection

Discovery of 12-Thiazole Abietanes as Selective Inhibitors of the Human Metabolic Serine Hydrolase hABHD16A

Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12)

Electrospray ionization mass spectrometry and tandem mass spectrometry of clodronate and related bisphosphonate and phosphonate compounds

Eudismic analysis of tricyclic sesquiterpenoid alcohols: lead structures for the design of potent inhibitors of the human UDP-glucuronosyltransferase 2B7

Exploring marine resources for bioactive compounds.

Exploring the scope of the 29G12 antibody catalyzed 1,3-dipolar cycloaddition reaction

Functionalization of carboxylated lignin nanoparticles for targeted and pH-responsive delivery of anticancer drugs

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases

HIV-1 Tat-peptide inhibits protein kinase C and protein kinase A through substrate competition

Identification of free and conjugated metabolites of mesocarb in human urine by LC-MS/MS.

Inhibitory effect of the natural product betulin and its derivatives against the intracellular bacterium Chlamydia pneumoniae.

Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma

In vitro evaluation of biodegradable lignin-based nanoparticles for drug delivery and enhanced antiproliferation effect in cancer cells

Isoform-selective inhibition of the human UDP-glucuronosyltransferase 2B7 by isolongifolol derivatives

Ketamine-induced regulation of TrkB-GSK3β signaling is accompanied by slow EEG oscillations and sedation but is independent of hydroxynorketamine metabolites

Mass-tag enhanced immuno-laser desorption/ionization mass spectrometry for sensitive detection of intact protein antigens.

Mechanism of the Oxidation of Heptafulvenes to Tropones Studied by Online Mass Spectrometry and Density Functional Theory Calculations

Methadone increases intracellular calcium in SH-SY5Y and SH-EP1-halpha7 cells by activating neuronal nicotinic acetylcholine receptors

Microplate screening assay for binding of ligands to bovine or reindeer beta-lactoglobulins

Microwave-assisted synthesis of imidazoles: reaction of p-toluenesulfonylmethyl isocyanide and polymer-bound imines

Morphine, Oxycodone, Methadone and Its Enantiomers in Different Models of Nociception in the Rat

Natural Stilbenoids Have Anti-Inflammatory Properties in Vivo and Down-Regulate the Production of Inflammatory Mediators NO, IL6, and MCP1 Possibly in a PI3K/Akt-Dependent Manner

New derivatives of dehydroabietic acid target planktonic and biofilm bacteria in Staphylococcus aureus and effectively disrupt bacterial membrane integrity

Nucleophilic Substitution of Hydrogen Facilitated by Quinone Methide Moieties in Benzo[cd]azulen-3-ones

On the hydrolytic behavior of tinidazole, metronidazole, and ornidazole

Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development

Optimization of a High-Throughput 384-Well Plate-Based Screening Platform with Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 15442 Biofilms

Pharmacological characterization of noroxymorphone as a new opioid for spinal analgesia

Pharmacological properties of the ubiquitous natural product betulin

Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

Polyketide derivatives active against Botrytis cinerea in Gerbera hybrida.

Potent inhibitors of the human UDP-glucuronosyltransferase 2B7 derived from the sesquiterpenoid alcohol longifolol

Preparation and Characterization of Dentin Phosphophoryn-Derived Peptide-Functionalized Lignin Nanoparticles for Enhanced Cellular Uptake

Protein kinases as drug targets.

Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo

Quercetin-Based Modified Porous Silicon Nanoparticles for Enhanced Inhibition of Doxorubicin-Resistant Cancer Cells

Recent advances in 1,3-dipolar cycloaddition reactions on solid supports

Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation

Rigorous computational study reveals what docking overlooks: Double trouble from membrane association in protein kinase C modulators

Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C.