Lista de obras - Michelle Glass - Dominio Público Uruguay

100 years of modelling ligand-receptor binding and response: A focus on GPCRs

scientific article published on 28 February 2020

A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury

artículo científico publicado en 2012

A novel high-throughput assay for the quantitative assessment of receptor trafficking

artículo científico publicado en 2008

A novel population of progenitor cells expressing cannabinoid receptors in the subependymal layer of the adult normal and Huntington's disease human brain.

artículo científico publicado en 2006

A shifted repertoire of endocannabinoid genes in the zebrafish (Danio rerio).

artículo científico publicado en 2007

Alkyl indole-based cannabinoid type 2 receptor tools: Exploration of linker and fluorophore attachment

artículo científico publicado en 2017

Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease

artículo científico publicado en 2009

An evaluation of the operational model when applied to quantify functional selectivity

artículo científico publicado en 2018

An intact model for quantifying functional selectivity

artículo científico publicado en 2019

Anandamide receptor signal transduction

artículo científico publicado en 2009

Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice.

artículo científico publicado en 2010

Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor

artículo científico publicado en 2015

CB(1) and CB(2) receptor-mediated signalling: a focus on endocannabinoids

artículo científico publicado en 2002

Cannabinoid (CB(1)), GABA(A) and GABA(B) receptor subunit changes in the globus pallidus in Huntington's disease.

artículo científico publicado en 2009

Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence

scientific article published on 10 April 2019

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.

artículo científico publicado en 2017

Cannabinoid Receptor 1 trafficking and the role of the intracellular pool: implications for therapeutics

artículo científico publicado en 2010

Cannabinoid Receptor 2 (CB2) Signals via G-alpha-s and Induces IL-6 and IL-10 Cytokine Secretion in Human Primary Leukocytes

artículo científico publicado en 2019

Cannabinoid Receptor 2 Signalling Bias Elicited by 2,4,6-Trisubstituted 1,3,5-Triazines

article

Cannabinoid Receptors: A brief history and what not

artículo científico publicado en 2009

Cannabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway

artículo científico publicado en 2011

Cannabinoid receptor CB2 is expressed on vascular cells, but not astroglial cells in the post-mortem human Huntington's disease brain.

artículo científico publicado en 2014

Cannabinoid receptors in invertebrates.

artículo científico publicado en 2006

Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain

artículo científico publicado en 1997

Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism

artículo científico publicado en 2007

Cannabis, cannabinoids and reproduction

artículo científico publicado en 2004

Cerebral hypoxia-ischemia and middle cerebral artery occlusion induce expression of the cannabinoid CB2 receptor in the brain

artículo científico publicado en 2006

Characterization of NTera2/D1 cells as a model system for the investigation of cannabinoid function in human neurons and astrocytes

artículo científico publicado en 2011

Characterization of the endocannabinoid system in early human pregnancy

artículo científico publicado en 2004

Chromenopyrazole-based High Affinity, Selective Fluorescent Ligands for Cannabinoid Type 2 Receptor

artículo científico publicado en 2019

Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk?

artículo científico publicado en 2005

Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors

artículo científico publicado en 2004

Development of positive control tissue for in situ hybridisation using Alvetex scaffolds

artículo científico publicado en 2014

Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1,8-naphthyridin-2-(1)-one-3-carboxamide scaffold

article

Differential activation of G-proteins by mu-opioid receptor agonists

artículo científico publicado en 2006

Distinct Temporal Fingerprint for Cyclic Adenosine Monophosphate (cAMP) Signaling of Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid Receptors.

artículo científico publicado en 2015

Do Toxic Synthetic Cannabinoid Receptor Agonists Have Signature in Vitro Activity Profiles? A Case Study of AMB-FUBINACA

scientific article published on 24 September 2019

Effects of bioisosteric fluorine in synthetic cannabinoid designer drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135.

artículo científico publicado en 2015

Effects of the Parkinsonian toxin MPP+ on electrophysiological properties of nigral dopaminergic neurons

artículo científico publicado en 2014

Evaluation of the profiles of CB1 cannabinoid receptor signalling bias using joint kinetic modelling

scientific article published on 15 April 2020

Evolutionary origins of the endocannabinoid system

article

Exploring Stereochemical and Conformational Requirements at Cannabinoid Receptors for Synthetic Cannabinoids Related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA

artículo científico publicado en 2020

Functional mapping of cannabinoid receptor homologs in mammals, other vertebrates, and invertebrates

artículo científico publicado en 2003

GPR18 undergoes a high degree of constitutive trafficking but is unresponsive to N-Arachidonoyl Glycine

artículo científico publicado en 2016

Gαs signalling of the CB1 receptor and the influence of receptor number

artículo científico publicado en 2017

High throughput quantification of mutant huntingtin aggregates

artículo científico publicado en 2008

Identification of N-arachidonoyl dopamine as a highly biased ligand at cannabinoid CB1 receptors

artículo científico publicado en 2015

Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor

artículo científico publicado en 2000

Increasing the flexibility of the LANCE cAMP detection kit

scholarly article by Morag Rose Hunter & Michelle Glass published January 2015 in Journal of Pharmacological and Toxicological Methods

Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway.

artículo científico publicado en 2006

Is the Cannabinoid CB2 Receptor a Major Regulator of the Neuroinflammatory Axis of the Neurovascular Unit in Humans?

artículo científico publicado en 2017

Localisation of the adenosine uptake site in the human brain: a comparison with the distribution of adenosine A1 receptors.

artículo científico publicado en 1996

Loss of A1 adenosine receptors in human temporal lobe epilepsy

artículo científico publicado en 1996

Loss of cannabinoid receptors in the substantia nigra in Huntington's disease.

artículo científico publicado en 1993

M1 muscarinic receptor activation mediates cell death in M1-HEK293 cells

artículo científico publicado en 2013

Meta-analysis of cannabinoid ligand binding affinity and receptor distribution: interspecies differences.

artículo científico publicado en 2007

Misidentification of prostamides as prostaglandins

artículo científico publicado en 2005

Model-free and kinetic modelling approaches for characterising non-equilibrium pharmacological pathway activity: Internalisation of cannabinoid CB1 receptors

scientific article published on 21 May 2019

Modulation of neurotransmission by cannabinoids in the basal ganglia

artículo científico publicado en 1997

Neurochemical and morphological changes associated with human epilepsy

scientific article published on 01 July 1995

Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.

artículo científico publicado en 2010

Nuclear localisation of the endocannabinoid metabolizing enzyme fatty acid amide hydrolase (FAAH) in invasive trophoblasts and an association with recurrent miscarriage

artículo científico publicado en 2008

One for the Price of Two…Are Bivalent Ligands Targeting Cannabinoid Receptor Dimers Capable of Simultaneously Binding to both Receptors?

artículo científico publicado en 2016

Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA.

artículo científico publicado en 2015

Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues

artículo científico publicado en 2016

Real-Time Measurement of Cannabinoid Receptor-Mediated cAMP Signaling.

artículo científico publicado en 2017

Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action

artículo científico publicado en 2013

Real-time profiling of NK cell killing of human astrocytes using xCELLigence technology

artículo científico publicado en 2011

Sensitive and accurate quantification of human leukocyte migration using high-content Discovery-1 imaging system and ATPlite assay.

artículo científico publicado en 2011

Signalling profiles of a structurally diverse panel of synthetic cannabinoid receptor agonists

artículo científico publicado en 2020

Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal!

artículo científico publicado en 2008

Structure–activity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologues

Sulfation of the FLAG epitope is affected by co-expression of G protein-coupled receptors in a mammalian cell model

artículo científico publicado en 2016

Synthesis and pharmacology of new psychoactive substance 5F-CUMYL-P7AICA, a scaffold- hopping analog of synthetic cannabinoid receptor agonists 5F-CUMYL-PICA and 5F-CUMYL-PINACA

artículo científico publicado en 2018

Synthetic cannabis: adverse events reported to the New Zealand Pharmacovigilance Centre

artículo científico publicado en 2020

The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities

artículo científico publicado en 2016

The cannabinoid CB2 receptor as a target for inflammation-dependent neurodegeneration

artículo científico publicado en 2007

The chemistry and pharmacology of putative synthetic cannabinoid receptor agonist (SCRA) new psychoactive substances (NPS) 5F-PY-PICA, 5F-PY-PINACA, and their analogs

scientific article published on 08 May 2019

The endocannabinoid system as a target for the treatment of neurodegenerative disease

artículo científico publicado en 2010

The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease

artículo científico publicado en 2000

The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse

artículo científico publicado en 2013

The therapeutic potential of G-protein coupled receptors in Huntington's disease

artículo científico publicado en 2010

c-fos antisense reduces expression of Krox 24 in rat caudate and neocortex

artículo científico publicado en 1994

Lista de obras de Michelle Glass

100 years of modelling ligand-receptor binding and response: A focus on GPCRs

A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury

A novel high-throughput assay for the quantitative assessment of receptor trafficking

A novel population of progenitor cells expressing cannabinoid receptors in the subependymal layer of the adult normal and Huntington's disease human brain.

A shifted repertoire of endocannabinoid genes in the zebrafish (Danio rerio).

Alkyl indole-based cannabinoid type 2 receptor tools: Exploration of linker and fluorophore attachment

Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease

An evaluation of the operational model when applied to quantify functional selectivity

An intact model for quantifying functional selectivity

Anandamide receptor signal transduction

Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice.

Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor

CB(1) and CB(2) receptor-mediated signalling: a focus on endocannabinoids

Cannabinoid (CB(1)), GABA(A) and GABA(B) receptor subunit changes in the globus pallidus in Huntington's disease.

Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.

Cannabinoid Receptor 1 trafficking and the role of the intracellular pool: implications for therapeutics

Cannabinoid Receptor 2 (CB2) Signals via G-alpha-s and Induces IL-6 and IL-10 Cytokine Secretion in Human Primary Leukocytes

Cannabinoid Receptor 2 Signalling Bias Elicited by 2,4,6-Trisubstituted 1,3,5-Triazines

Cannabinoid Receptors: A brief history and what not

Cannabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway

Cannabinoid receptor CB2 is expressed on vascular cells, but not astroglial cells in the post-mortem human Huntington's disease brain.

Cannabinoid receptors in invertebrates.

Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain

Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism

Cannabis, cannabinoids and reproduction

Cerebral hypoxia-ischemia and middle cerebral artery occlusion induce expression of the cannabinoid CB2 receptor in the brain

Characterization of NTera2/D1 cells as a model system for the investigation of cannabinoid function in human neurons and astrocytes

Characterization of the endocannabinoid system in early human pregnancy

Chromenopyrazole-based High Affinity, Selective Fluorescent Ligands for Cannabinoid Type 2 Receptor

Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk?

Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors

Development of positive control tissue for in situ hybridisation using Alvetex scaffolds

Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1,8-naphthyridin-2-(1)-one-3-carboxamide scaffold

Differential activation of G-proteins by mu-opioid receptor agonists

Distinct Temporal Fingerprint for Cyclic Adenosine Monophosphate (cAMP) Signaling of Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid Receptors.

Do Toxic Synthetic Cannabinoid Receptor Agonists Have Signature in Vitro Activity Profiles? A Case Study of AMB-FUBINACA

Effects of bioisosteric fluorine in synthetic cannabinoid designer drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135.

Effects of the Parkinsonian toxin MPP+ on electrophysiological properties of nigral dopaminergic neurons

Evaluation of the profiles of CB1 cannabinoid receptor signalling bias using joint kinetic modelling

Evolutionary origins of the endocannabinoid system

Exploring Stereochemical and Conformational Requirements at Cannabinoid Receptors for Synthetic Cannabinoids Related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA

Functional mapping of cannabinoid receptor homologs in mammals, other vertebrates, and invertebrates

GPR18 undergoes a high degree of constitutive trafficking but is unresponsive to N-Arachidonoyl Glycine

Gαs signalling of the CB1 receptor and the influence of receptor number

High throughput quantification of mutant huntingtin aggregates

Identification of N-arachidonoyl dopamine as a highly biased ligand at cannabinoid CB1 receptors

Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor

Increasing the flexibility of the LANCE cAMP detection kit

Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2A cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway.

Is the Cannabinoid CB2 Receptor a Major Regulator of the Neuroinflammatory Axis of the Neurovascular Unit in Humans?

Localisation of the adenosine uptake site in the human brain: a comparison with the distribution of adenosine A1 receptors.

Loss of A1 adenosine receptors in human temporal lobe epilepsy

Loss of cannabinoid receptors in the substantia nigra in Huntington's disease.

M1 muscarinic receptor activation mediates cell death in M1-HEK293 cells

Meta-analysis of cannabinoid ligand binding affinity and receptor distribution: interspecies differences.

Misidentification of prostamides as prostaglandins

Model-free and kinetic modelling approaches for characterising non-equilibrium pharmacological pathway activity: Internalisation of cannabinoid CB1 receptors

Modulation of neurotransmission by cannabinoids in the basal ganglia

Neurochemical and morphological changes associated with human epilepsy

Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.

Nuclear localisation of the endocannabinoid metabolizing enzyme fatty acid amide hydrolase (FAAH) in invasive trophoblasts and an association with recurrent miscarriage

One for the Price of Two…Are Bivalent Ligands Targeting Cannabinoid Receptor Dimers Capable of Simultaneously Binding to both Receptors?

Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA.

Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues

Real-Time Measurement of Cannabinoid Receptor-Mediated cAMP Signaling.

Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action

Real-time profiling of NK cell killing of human astrocytes using xCELLigence technology

Sensitive and accurate quantification of human leukocyte migration using high-content Discovery-1 imaging system and ATPlite assay.

Signalling profiles of a structurally diverse panel of synthetic cannabinoid receptor agonists

Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal!

Structure–activity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologues

Sulfation of the FLAG epitope is affected by co-expression of G protein-coupled receptors in a mammalian cell model

Synthesis and pharmacology of new psychoactive substance 5F-CUMYL-P7AICA, a scaffold- hopping analog of synthetic cannabinoid receptor agonists 5F-CUMYL-PICA and 5F-CUMYL-PINACA

Synthetic cannabis: adverse events reported to the New Zealand Pharmacovigilance Centre

The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities

The cannabinoid CB2 receptor as a target for inflammation-dependent neurodegeneration

The chemistry and pharmacology of putative synthetic cannabinoid receptor agonist (SCRA) new psychoactive substances (NPS) 5F-PY-PICA, 5F-PY-PINACA, and their analogs

The endocannabinoid system as a target for the treatment of neurodegenerative disease