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Lista de obras de Natasha L. Grimsey

A novel high-throughput assay for the quantitative assessment of receptor trafficking

artículo científico publicado en 2008

Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells

artículo científico publicado en 2019

Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence

scientific article published on 10 April 2019

Cannabinoid Receptor 1 trafficking and the role of the intracellular pool: implications for therapeutics

artículo científico publicado en 2010

Cannabinoid Receptor 2 (CB2) Signals via G-alpha-s and Induces IL-6 and IL-10 Cytokine Secretion in Human Primary Leukocytes

artículo científico publicado en 2019

Cannabinoid Receptor 2 Signalling Bias Elicited by 2,4,6-Trisubstituted 1,3,5-Triazines

article

Cannabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway

artículo científico publicado en 2011

Cannabinoid receptor CB2 is expressed on vascular cells, but not astroglial cells in the post-mortem human Huntington's disease brain.

artículo científico publicado en 2014

Chromenopyrazole-based High Affinity, Selective Fluorescent Ligands for Cannabinoid Type 2 Receptor

artículo científico publicado en 2019

Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells

artículo científico publicado en 2020

Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1,8-naphthyridin-2-(1)-one-3-carboxamide scaffold

article

Drug Derived Fluorescent Probes for the Specific Visualization of Cannabinoid Type 2 Receptor - A Toolbox Approach

scholarly article

GPR18 undergoes a high degree of constitutive trafficking but is unresponsive to N-Arachidonoyl Glycine

artículo científico publicado en 2016

Gαs signalling of the CB1 receptor and the influence of receptor number

artículo científico publicado en 2017

Highly Specific, Fluorescent Cannabinoid Type 2 Receptor Probes Enable Applications in Microscopy, Flow Cytometry and FRET-based Binding Assays

Identification of N-arachidonoyl dopamine as a highly biased ligand at cannabinoid CB1 receptors

artículo científico publicado en 2015

Intracellular trafficking of cannabinoid receptor 1: a thorough characterisation and investigation into the role of the intracellular pool ⬇️

2010 doctoral thesis by Natasha Lillia Grimsey at University of Auckland

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists

scientific article published on 31 March 2020

Real-Time Measurement of Cannabinoid Receptor-Mediated cAMP Signaling.

artículo científico publicado en 2017

Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action

artículo científico publicado en 2013

Regulating membrane lipid levels at the synapse by small-molecule inhibitors of monoacylglycerol lipase: new developments in therapeutic and PET imaging applications

scientific article published on 14 October 2019

Sensitive and accurate quantification of human leukocyte migration using high-content Discovery-1 imaging system and ATPlite assay.

artículo científico publicado en 2011

Signalling profiles of a structurally diverse panel of synthetic cannabinoid receptor agonists

artículo científico publicado en 2020

Single nucleotide polymorphisms in the cannabinoid CB 2 receptor: Molecular pharmacology and disease associations

artículo científico publicado en 2024

Specific detection of CB1 receptors; cannabinoid CB1 receptor antibodies are not all created equal!

artículo científico publicado en 2008

Sulfation of the FLAG epitope is affected by co-expression of G protein-coupled receptors in a mammalian cell model

artículo científico publicado en 2016

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