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Lista de obras de Paula Gomes

"Clicking" an Ionic Liquid to a Potent Antimicrobial Peptide: On the Route towards Improved Stability

artículo científico publicado en 2020

"Recycling" classical drugs for malaria

artículo científico publicado en 2014

11(th) National Meeting of Organic Chemistry and 4(th) Meeting of Therapeutic Chemistry

artículo científico publicado en 2016

A 17-mer Membrane-Active MSI-78 Derivative with Improved Selectivity toward Bacterial Cells

artículo científico publicado en 2015

A Quinacrine Analogue Selective Against Gastric Cancer Cells: Insight from Biochemical and Biophysical Studies

artículo científico publicado en 2016

A biocompatible hybrid material with simultaneous calcium and strontium release capability for bone tissue repair

artículo científico publicado en 2016

A minocycline-releasing PMMA system as a space maintainer for staged bone reconstructions-in vitro antibacterial, cytocompatibility and anti-inflammatory characterization

artículo científico publicado en 2017

A novel synthetic peptide inspired on Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates.

artículo científico publicado en 2018

AMP-Chitosan Coating with Bactericidal Activity in the Presence of Human Plasma Proteins

artículo científico publicado en 2020

Acylation of the S4-PV cell-penetrating peptide as a means of enhancing its capacity to mediate nucleic acid delivery: Relevance of peptide/lipid interactions

scientific article published on 04 October 2018

Affinity-Triggered Assemblies Based on a Designed Peptide-Peptide Affinity Pair

scientific article published on 08 August 2019

Aminoglutethimide-imprinted xerogels in bulk and spherical formats, based on a multifunctional organo-alkoxysilane precursor

artículo científico publicado en 2015

Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones

artículo científico publicado en 2007

Anti-tumoral activity of imidazoquines, a new class of antimalarials derived from primaquine

artículo científico publicado en 2009

Antigenicity modulation upon peptide cyclization: application to the GH loop of foot-and-mouth disease virus strain C1-Barcelona.

artículo científico publicado en 2001

Antimicrobial coatings prepared from Dhvar-5-click-grafted chitosan powders

scientific article published on 05 December 2018

Antimicrobial peptides: a new class of antimalarial drugs?

artículo científico publicado en 2014

Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78.

artículo científico publicado en 2015

Bacteria-targeted biomaterials: Glycan-coated microspheres to bind Helicobacter pylori.

artículo científico publicado en 2016

Biomimetic mineralization on a macroporous cellulose-based matrix for bone regeneration

artículo científico publicado en 2013

Bionanoconjugates of tyrosinase and peptide-derivatised gold nanoparticles for biosensing of phenolic compounds

Bisphosphonates induce the osteogenic gene expression in co-cultured human endothelial and mesenchymal stem cells.

artículo científico publicado en 2013

Bone Cells Dynamics during Peri-Implantitis: a Theoretical Analysis

artículo científico publicado en 2016

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3

scientific article published on 30 June 2018

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5

scientific article published on 30 June 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6

scientific article published on 28 December 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4

scientific article published on 31 December 2018

Carcinogenic liver fluke Opisthorchis viverrini oxysterols detected by LC-MS/MS survey of soluble fraction parasite extract.

scientific article published on 20 August 2013

Cell-induced response by tetracyclines on human bone marrow colonized hydroxyapatite and Bonelike.

artículo científico publicado en 2008

Characterization of Sensory Properties of Flavanols--A Molecular Dynamic Approach

artículo científico publicado en 2015

Characterization of hLF1-11 immobilization onto chitosan ultrathin films, and its effects on antimicrobial activity

artículo científico publicado en 2014

Chloroquine Analogues as Leads against Pneumocystis Lung Pathogens

artículo científico publicado en 2018

Cinnamic Acid Conjugates in the Rescuing and Repurposing of Classical Antimalarial Drugs

artículo científico publicado en 2019

Cinnamic acid/chloroquinoline conjugates as potent agents against chloroquine-resistant Plasmodium falciparum

artículo científico publicado en 2012

Clinical Application of AMPs

scientific article published on 01 January 2019

Comparison of the Efficiency of Complexes Based on S413-PV Cell-Penetrating Peptides in Plasmid DNA and siRNA Delivery ⬇️

artículo científico publicado el 10 de junio de 2013

Coupling the Antimalarial Cell Penetrating Peptide TP10 to Classical Antimalarial Drugs Primaquine and Chloroquine Produces Strongly Hemolytic Conjugates

artículo científico publicado en 2019

Coupling the cell-penetrating peptides transportan and transportan 10 to primaquine enhances its activity against liver-stage malaria parasites

scholarly article by Luísa Aguiar et al published 1 February 2019 in MedChemComm

Covalent immobilization of antimicrobial peptides (AMPs) onto biomaterial surfaces.

artículo científico publicado en 2010

Cross-species comparison of mammalian saliva using an LC-MALDI based proteomic approach

artículo científico publicado en 2015

Cyclization-activated prodrugs.

artículo científico publicado en 2007

Cyclization-activated prodrugs. Synthesis, reactivity and toxicity of dipeptide esters of paracetamol

artículo científico publicado en 2005

Cytotoxicity evaluation of nanocrystalline diamond coatings by fibroblast cell cultures.

artículo científico publicado en 2008

Defensins in the oral cavity: distribution and biological role.

artículo científico publicado en 2009

Development of hydroxyapatite nanoparticles loaded with folic acid to induce osteoblastic differentiation.

artículo científico publicado en 2016

Dhvar5 antimicrobial peptide (AMP) chemoselective covalent immobilization results on higher antiadherence effect than simple physical adsorption.

artículo científico publicado en 2015

Diels-Alder functionalized carbon nanotubes for bone tissue engineering: in vitro/in vivo biocompatibility and biodegradability.

artículo científico publicado en 2015

Dipeptide derivatives of AZT: synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity

artículo científico publicado en 2008

Direct kinetic assay of interactions between small peptides and immobilized antibodies using a surface plasmon resonance biosensor

artículo científico publicado en 2002

Direct single-step surface plasmon resonance analysis of interactions between small peptides and immobilized monoclonal antibodies

artículo científico publicado en 2000

Dynamics of an antibiotic oligopeptide

article

Effect of Sterilization Methods on Electrospun Poly(lactic acid) (PLA) Fiber Alignment for Biomedical Applications.

artículo científico publicado en 2016

Effect of surface coating on the biodistribution profile of gold nanoparticles in the rat.

artículo científico publicado en 2011

Effect of therapeutic levels of doxycycline and minocycline in the proliferation and differentiation of human bone marrow osteoblastic cells

artículo científico publicado en 2006

Effects of novel triple-stage antimalarial ionic liquids on lipid membrane models

artículo científico publicado en 2017

Efficacy and Cytotoxicity of Binary Mixtures as Root Canal Filling Solvents

artículo científico publicado en 2020

Electrospray ionization mass spectrometry as a valuable tool in the characterization of novel primaquine peptidomimetic derivatives

artículo científico publicado en 2009

Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine

artículo científico publicado en 2008

Encapsulated bacteriophages in alginate-nanohydroxyapatite hydrogel as a novel delivery system to prevent orthopedic implant-associated infections

scientific article published on 17 December 2019

EndoProteoFASP as a Tool to Unveil the Peptidome-Protease Profile: Application to Salivary Diagnostics

artículo científico publicado en 2018

Energetics and partition of two cecropin-melittin hybrid peptides to model membranes of different composition

artículo científico publicado en 2007

Equisetum arvense hydromethanolic extracts in bone tissue regeneration: in vitro osteoblastic modulation and antibacterial activity.

artículo científico publicado en 2012

Evaluation of human osteoblastic cell response to plasma-sprayed silicon-substituted hydroxyapatite coatings over titanium substrates

artículo científico publicado en 2010

Gemcitabine anti-proliferative activity significantly enhanced upon conjugation with cell-penetrating peptides.

artículo científico publicado en 2017

Grafting Techniques towards Production of Peptide-Tethered Hydrogels, a Novel Class of Materials with Biomedical Interest

scientific article published on 21 October 2015

Growth and phenotypic expression of human endothelial cells cultured on a glass-reinforced hydroxyapatite.

artículo científico publicado en 2008

Harnessing snake venom phospholipases A2 to novel approaches for overcoming antibiotic resistance

scientific article published on 26 September 2018

Heparan sulphate mediates swine vesicular disease virus attachment to the host cell

artículo científico

Hydration water and peptide dynamics--two sides of a coin. A neutron scattering and adiabatic calorimetry study at low hydration and cryogenic temperatures

artículo científico publicado en 2013

Identification of T-cell epitopes in nonstructural proteins of foot-and-mouth disease virus.

artículo científico publicado en 2001

Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials

artículo científico publicado en 2005

Imidazolidin-4-one peptidomimetic derivatives of primaquine: synthesis and antimalarial activity

artículo científico publicado en 2008

Imidazolium-based functional monomers for the imprinting of the anti-inflammatory drug naproxen: comparison of acrylic and sol-gel approaches

artículo científico publicado en 2013

Imidazoquines as antimalarial and antipneumocystis agents

scientific article published on December 2009

ImmunoPEGliposomes for the targeted delivery of novel lipophilic drugs to red blood cells in a falciparum malaria murine model

artículo científico publicado en 2017

In Vitro Evaluation of Five Antimicrobial Peptides against the Plant Pathogen Erwinia amylovora

artículo científico publicado en 2021

In the trail of a new bio-sensor for measuring strain in bone: osteoblastic biocompatibility.

artículo científico publicado en 2011

In vitro efficiency of 9-(N-cinnamoylbutyl)aminoacridines against blood- and liver-stage malaria parasites

artículo científico publicado en 2012

In vitro evaluation of Portuguese propolis and floral sources for antiprotozoal, antibacterial and antifungal activity

artículo científico publicado en 2013

In vivo assessment of a new multifunctional coating architecture for improved Mg alloy biocompatibility

artículo científico publicado en 2016

In vivo tissue response and antibacterial efficacy of minocycline delivery system based on polymethylmethacrylate bone cement

scientific article published on 01 September 2018

Incorporation of glass-reinforced hydroxyapatite microparticles into poly(lactic acid) electrospun fibre mats for biomedical applications.

artículo científico publicado en 2017

Increased DNA damage and cell death on exfoliated buccal epithelial cells upon CPAP therapy with oro-nasal interface

artículo científico publicado en 2016

Insights into the Membranolytic Activity of Antimalarial Drug-Cell Penetrating Peptide Conjugates

artículo científico publicado en 2020

Interaction and lipid-induced conformation of two cecropin-melittin hybrid peptides depend on peptide and membrane composition

artículo científico publicado en 2005

Interaction between Wine Phenolic Acids and Salivary Proteins by Saturation-Transfer Difference Nuclear Magnetic Resonance Spectroscopy (STD-NMR) and Molecular Dynamics Simulations.

artículo científico publicado en 2017

Ionic liquids for Topical Delivery in Cancer

artículo científico publicado en 2019

Killing of Mycobacterium avium by lactoferricin peptides: improved activity of arginine- and D-amino-acid-containing molecules

artículo científico publicado en 2014

Levofloxacin-loaded bone cement delivery system: highly effective against intracellular bacteria and Staphylococcus aureus biofilms.

artículo científico publicado en 2017

Mass spectrometry techniques in the survey of steroid metabolites as potential disease biomarkers: a review

artículo científico publicado en 2013

Mastocytosis: oral implications of a rare disease.

artículo científico publicado en 2010

Melanoma targeting with alpha-melanocyte stimulating hormone analogs labeled with fac-[99mTc(CO)3]+: effect of cyclization on tumor-seeking properties.

artículo científico publicado en 2008

Membrane structure and interactions of a short Lycotoxin I analogue

artículo científico publicado en 2008

Microanalysis of Bioactive Samarium Doped Glass-Reinforced Hydroxyapatite

artículo científico publicado en 2015

Model Amphipathic Peptide Coupled with Tacrine to Improve Its Antiproliferative Activity

artículo científico publicado en 2020

Molecular analysis of peptides from the GH loop of foot-and-mouth disease virus C-S30 using surface plasmon resonance: a role for kinetic rate constants.

artículo científico publicado en 2000

Multifunctional PLLA-ceramic fiber membranes for bone regeneration applications.

artículo científico publicado en 2017

Multifunctional carbon nanotube/bioceramics modulate the directional growth and activity of osteoblastic cells.

artículo científico publicado en 2014

N-Cinnamoylation of Antimalarial Classics: Effects of Using Acyl Groups Other than Cinnamoyl toward Dual-Stage Antimalarials

artículo científico publicado en 2015

N-acetylcysteine-functionalized coating avoids bacterial adhesion and biofilm formation.

artículo científico publicado en 2017

N-cinnamoylated chloroquine analogues as dual-stage antimalarial leads

artículo científico publicado en 2013

N-cinnamoylation of antimalarial classics: quinacrine analogues with decreased toxicity and dual-stage activity

artículo científico publicado en 2013

Nano-hydroxyapatite in oral care cosmetics: characterization and cytotoxicity assessment

scientific article published on 30 July 2019

Nanocrystalline diamond: In vitro biocompatibility assessment by MG63 and human bone marrow cells cultures

artículo científico publicado en 2008

New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins

artículo científico publicado en 2017

New times, new trends for ethionamide: In vitro evaluation of drug-loaded thermally carbonized porous silicon microparticles.

artículo científico publicado en 2012

New titanium and titanium/hydroxyapatite coatings on ultra-high-molecular-weight polyethylene-in vitro osteoblastic performance

artículo científico publicado en 2010

Nitric Oxide Release from Antimicrobial Peptide Hydrogels for Wound Healing

scientific article published in 2018

Novel cerium doped glass-reinforced hydroxyapatite with antibacterial and osteoconductive properties for bone tissue regeneration.

artículo científico publicado en 2015

Novel cinnamic acid/4-aminoquinoline conjugates bearing non-proteinogenic amino acids: towards the development of potential dual action antimalarials

artículo científico publicado en 2012

Novel potent metallocenes against liver stage malaria

artículo científico publicado en 2011

Orofacial manifestations in outpatients with anorexia nervosa and bulimia nervosa focusing on the vomiting behavior.

artículo científico publicado en 2017

PDMS-SiO2-TiO2-CaO hybrid materials - Cytocompatibility and nanoscale surface features.

artículo científico publicado en 2016

PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity

PRIMACINS, N-cinnamoyl-primaquine conjugates, with improved liver-stage antimalarial activity

Peptide-Based Drugs and Drug Delivery Systems.

artículo científico publicado en 2017

Phenolic Profiling of Portuguese Propolis by LC–MS Spectrometry: Uncommon Propolis Rich in Flavonoid Glycosides ⬇️

artículo científico publicado el 22 de noviembre de 2012

Phenolic quantification and botanical origin of Portuguese propolis

article

Physicochemical and toxicological properties of novel amino acid-based amphiphiles and their spontaneously formed catanionic vesicles

artículo científico publicado en 2009

Plasma catecholamines during an ultrarapid heroin detoxification

scientific article published on 01 September 2000

Potential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents

scientific article published on 24 August 2019

Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs

artículo científico publicado en 2009

Primaquine revisited six decades after its discovery

artículo científico publicado en 2008

Probing degeneracy in antigen-antibody recognition at the immunodominant site of foot-and-mouth disease virus.

artículo científico publicado en 2002

Processing strategies for smart electroconductive carbon nanotube-based bioceramic bone grafts.

artículo científico publicado en 2014

Radiochemical and biological evaluation of novel153Sm/166Ho-amino acid-chitosan complexes

Recycling antimalarial leads for cancer: Antiproliferative properties of N-cinnamoyl chloroquine analogues

artículo científico publicado en 2013

Relevance of the sterilization-induced effects on the properties of different hydroxyapatite nanoparticles and assessment of the osteoblastic cell response.

artículo científico publicado en 2012

Rodent models in bone-related research: the relevance of calvarial defects in the assessment of bone regeneration strategies.

artículo científico publicado en 2010

S4(13)-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA.

artículo científico publicado en 2008

S4(13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: implications for cell internalization

artículo científico publicado en 2011

Samarium doped glass-reinforced hydroxyapatite with enhanced osteoblastic performance and antibacterial properties for bone tissue regeneration

artículo científico publicado en 2014

Schistosoma haematobium: identification of new estrogenic molecules with estradiol antagonistic activity and ability to inactivate estrogen receptor in mammalian cells

artículo científico publicado en 2010

Selective albumin-binding surfaces modified with a thrombin-inhibiting peptide.

artículo científico publicado en 2013

Silicate and borate glasses as composite fillers: a bioactivity and biocompatibility study

artículo científico publicado en 2011

Smart electroconductive bioactive ceramics to promote in situ electrostimulation of bone

artículo científico publicado en 2015

Spontaneous vesicle formation in catanionic mixtures of amino acid-based surfactants: chain length symmetry effects.

artículo científico publicado en 2008

Striking HIV-1 Entry by Targeting HIV-1 gp41. But, Where Should We Target?

artículo científico publicado en 2016

Structure and function of a novel antioxidant peptide from the skin of tropical frogs

artículo científico publicado en 2017

Structure-activity relationships for dipeptide prodrugs of acyclovir: implications for prodrug design

artículo científico publicado en 2008

Structure-function studies of BPP-BrachyNH2 and synthetic analogues thereof with Angiotensin I-Converting Enzyme

artículo científico publicado en 2017

Structure/property relationships for the thermotropic behavior of lysine-based amphiphiles: from hexagonal to smectic phases

artículo científico publicado en 2008

Tethering antimicrobial peptides onto chitosan: Optimization of azide-alkyne "click" reaction conditions.

artículo científico publicado en 2017

The 1st Baltic Osseointegration Academy and Lithuanian University of Health Sciences Consensus Conference 2016. Summary and Consensus Statements: Group I - Peri-Implantitis Aetiology, Risk Factors and Pathogenesis

artículo científico publicado en 2016

The Osteogenic Priming of Mesenchymal Stem Cells is Impaired in Experimental Diabetes

artículo científico publicado en 2015

The biomaterial-mediated healing of critical size bone defects in the ovariectomized rat.

artículo científico publicado en 2014

The diagnosis of eating disorders through mid-infrared spectroscopy of the gingival crevicular fluid: a pilot trial

The effects of intense pulsed light in a mouse model of skin carcinogenesis

artículo científico publicado en 2015

Toward the definition of a peptidome signature and protease profile in chronic periodontitis

artículo científico publicado en 2015

Toward the discovery of inhibitors of babesipain-1, a Babesia bigemina cysteine protease: in vitro evaluation, homology modeling and molecular docking studies

artículo científico publicado en 2013

Towards a Sustainable Management of the Spotted-Wing Drosophila: Disclosing the Effects of Two Spider Venom Peptides on Drosophila suzukii

artículo científico publicado en 2023

Tumour-like phenotypes in urothelial cells after exposure to antigens from eggs of Schistosoma haematobium: an oestrogen-DNA adducts mediated pathway?

artículo científico publicado en 2012

Unanticipated stereoselectivity in the reaction of primaquine alpha-aminoamides with substituted benzaldehydes: a computational and experimental study

artículo científico publicado en 2007

Uncovering the molecular networks in periodontitis ⬇️

artículo científico

Unravelling a Mechanism of Action for a Cecropin A-Melittin Hybrid Antimicrobial Peptide: The Induced Formation of Multilamellar Lipid Stacks

artículo científico publicado en 2018

Urinary estrogen metabolites and self-reported infertility in women infected with Schistosoma haematobium

artículo científico publicado en 2014

Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries

artículo científico publicado en 2017

endoProteoFASP: a novel FASP approach to profile salivary peptidome and disclose salivary proteases.

artículo científico publicado en 2014

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