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Lista de obras de Gianluca Tell

A Potent HIV Protease Inhibitor Identified in an Epimeric Mixture by High-Resolution Protein Crystallography

article

A chicken hnRNP of the A/B family recognizes the single-stranded d(CCCTAA)(n) telomeric repeated motif.

artículo científico publicado en 2001

A differential proteomic approach to identify proteins associated with thyroid cell transformation.

artículo científico publicado en 2005

A molecular code dictates sequence-specific DNA recognition by homeodomains.

artículo científico publicado en 1996

A proteomic approach to identify early molecular targets of oxidative stress in human epithelial lens cells

artículo científico publicado en 2004

A proteomic approach to the bilirubin-induced toxicity in neuronal cells reveals a protective function of DJ-1 protein

artículo científico publicado en 2010

A review on protein-protein interaction network of APE1/Ref-1 and its associated biological functions

artículo científico

A short review on the implications of base excision repair pathway for neurons: relevance to neurodegenerative diseases

artículo científico publicado en 2013

A unique combination of transcription factors controls differentiation of thyroid cells

artículo científico publicado en 2001

APE/Ref-1 is increased in nuclear fractions of human thyroid hyperfunctioning nodules.

artículo científico publicado en 2002

APE1 polymorphic variants cause persistent genomic stress and affect cancer cell proliferation

artículo científico publicado en 2016

APE1/Ref-1 in Alzheimer's disease: an immunohistochemical study

artículo científico publicado en 2009

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

artículo científico publicado en 2009

APE1/Ref-1 redox function contributes to inflammatory pain sensitization

scientific article published on 14 May 2018

APE1/Ref-1 regulates PTEN expression mediated by Egr-1

artículo científico publicado en 2008

Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2.

artículo científico publicado en 2017

Acetylation on critical lysine residues of Apurinic/apyrimidinic endonuclease 1 (APE1) in triple negative breast cancers

artículo científico publicado en 2012

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP

artículo científico publicado en 2005

Activation of human T lymphocytes under conditions similar to those that occur during exposure to microgravity: a proteomics study

artículo científico publicado en 2005

Adhesion to fibronectin promotes the activation of the p125(FAK)/Zap-70complex in human T cells.

artículo científico publicado en 1999

Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations.

artículo científico publicado en 2008

Alterations in the redox state and liver damage: hints from the EASL Basic School of Hepatology.

artículo científico

Altered intracellular redox status in Gaucher disease fibroblasts and impairment of adaptive response against oxidative stress

artículo científico publicado en 2007

An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

artículo científico publicado en 2000

Analysis of the solution structure of the homeodomain of rat thyroid transcription factor 1 by 1H-NMR spectroscopy and restrained molecular mechanics

artículo científico publicado en 1996

Architecture of The Human Ape1 Interactome Defines Novel Cancers Signatures

scientific article published on 08 January 2020

Autocrine/paracrine stimulation of purinergic receptors in osteoblasts: contribution of vesicular ATP release

artículo científico publicado en 2005

BIPHASIC CONTROL OF NF-κB ACTIVATION INDUCED BY THE TRIGGERING OF HLA-DR ANTIGENS EXPRESSED ON B CELLS

scientific article published on 01 May 1997

BRCA1 modulates the expression of hnRNPA2B1 and KHSRP.

artículo científico publicado en 2010

Base excision repair in Archaea: back to the future in DNA repair

artículo científico

Bilirubin-induced cell toxicity involves PTEN activation through an APE1/Ref-1-dependent pathway

artículo científico publicado en 2007

Bisphosphonates activate nucleotide receptors signaling and induce the expression of Hsp90 in osteoblast-like cell lines

artículo científico publicado en 2006

Cadmium treatment suppresses DNA polymerase δ catalytic subunit gene expression by acting on the p53 and Sp1 regulatory axis

artículo científico publicado en 2015

Calreticulin enhances the transcriptional activity of thyroid transcription factor-1 by binding to its homeodomain

artículo científico publicado en 1999

Cleavage of the APE1 N-Terminal Domain in Acute Myeloid Leukemia Cells Is Associated with Proteasomal Activity

scientific article published on 31 March 2020

Co-operation between the PAI and RED subdomains of Pax-8 in the interaction with the thyroglobulin promoter

artículo científico publicado en 1999

Combining RNAi and in vivo confocal microscopy analysis of the photoconvertible fluorescent protein Dendra2 to study a DNA repair protein

artículo científico publicado en 2013

Comparative stability analysis of the thyroid transcription factor 1 and Antennapedia homeodomains: evidence for residue 54 in controlling the structural stability of the recognition helix

artículo científico publicado en 1999

Control of phosphatase and tensin homolog (PTEN) gene expression in normal and neoplastic thyroid cells

artículo científico publicado en 2004

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.

artículo científico publicado en 2010

Cross-regulation between Egr-1 and APE/Ref-1 during early response to oxidative stress in the human osteoblastic HOBIT cell line: evidence for an autoregulatory loop

artículo científico publicado en 2005

Cytosine-block telomeric type DNA-binding activity of hnRNP proteins from human cell lines.

artículo científico publicado en 2003

DNA repair enzyme APE1 from evolutionarily ancient Hydra reveals redox activity exclusively found in mammalian APE1.

artículo científico publicado en 2017

Definition of the DNA-binding specificity of TTF-1 homeodomain by chromatographic selection of binding sequences

artículo científico publicado en 1995

DeltaNp73alpha inhibits PTEN expression in thyroid cancer cells

artículo científico publicado en 2009

Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia.

artículo científico publicado en 2016

Detection of aromatic catabolic gene expression in heterogeneous organic matter used for reduction of volatile organic compounds (VOC) by biofiltration.

artículo científico publicado en 2006

Differential proteomic analysis of nuclear extracts from thyroid cell lines

artículo científico publicado en 2006

Differential proteomic analysis of subfractioned human hepatocellular carcinoma tissues.

artículo científico publicado en 2009

Down-regulation of SM22/transgelin gene expression during H9c2 cells differentiation.

artículo científico publicado en 2009

Effect of phosphorothioate modifications on the ability of GTn oligodeoxynucleotides to specifically recognize single-stranded DNA-binding proteins and to affect human cancer cellular growth.

artículo científico publicado en 1999

Effect of salt concentration on TTF-1 HD binding to specific and non-specific DNA sequences

artículo científico

Effects of histone acetylation on sodium iodide symporter promoter and expression of thyroid-specific transcription factors

artículo científico publicado en 2005

Emerging roles of the nucleolus in regulating the DNA damage response: the noncanonical DNA repair enzyme APE1/Ref-1 as a paradigmatical example

artículo científico publicado en 2014

Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination

artículo científico publicado en 2019

Expression and Prognostic Significance of APE1/Ref-1 and NPM1 Proteins in High-Grade Ovarian Serous Cancer

scientific article published on 01 March 2014

Expression and function of the homeodomain-containing protein Hex in thyroid cells

artículo científico publicado en 2000

Expression and localization of the homeodomain-containing protein HEX in human thyroid tumors

artículo científico publicado en 2002

Expression of Dicer and Drosha in triple-negative breast cancer.

artículo científico publicado en 2012

Expression, purification and functional characterisation of a Kunitz-type module from chicken type VI collagen.

artículo científico publicado en 1995

Expression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell lines

artículo científico publicado en 2005

Extracellular ATP stimulates the early growth response protein 1 (Egr-1) via a protein kinase C-dependent pathway in the human osteoblastic HOBIT cell line

artículo científico publicado en 2003

Extracellular nucleotides activate Runx2 in the osteoblast-like HOBIT cell line: a possible molecular link between mechanical stress and osteoblasts' response

artículo científico publicado en 2005

Fibronectin binding promotes a PKC-dependent modulation of NF-kappa B in human T cells

scientific article published on 01 February 1998

Functional analysis of a novel RUNX2 missense mutation found in a family with cleidocranial dysplasia

artículo científico publicado en 2005

Functional interaction among thyroid-specific transcription factors: Pax8 regulates the activity of Hex promoter

artículo científico publicado en 2004

Functional interference between contacting amino acids of homeodomains.

artículo científico publicado en 1997

Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology

artículo científico publicado en 2015

Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.

artículo científico publicado en 2013

G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection.

artículo científico publicado en 2014

Galectin-3 expression in non-small cell lung carcinoma

Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells.

artículo científico publicado en 2009

Glyceraldehyde 3-phosphate-induced DNA or protein modifications severely inhibit the protein/DNA interaction

artículo científico

H(2)O(2) induces translocation of APE/Ref-1 to mitochondria in the Raji B-cell line

artículo científico publicado en 2002

H(2)O(2) modulates purinergic-dependent calcium signalling in osteoblast-like cells

artículo científico publicado en 2007

High mobility group I proteins interfere with the homeodomains binding to DNA.

artículo científico publicado en 1997

Human AP endonuclease/redox factor APE1/ref-1 modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1

artículo científico publicado en 2012

Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence

artículo científico publicado en 2018

Hydrogen-deuterium exchange studies of the rat thyroid transcription factor 1 homeodomain

artículo científico publicado el 1 de junio de 1997

Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers

artículo científico publicado en 2003

Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection.

artículo científico publicado en 2009

Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice

artículo científico publicado en 2015

In the TTF-1 homeodomain the contribution of several amino acids to DNA recognition depends on the bound sequence

artículo científico publicado en 1996

Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties

artículo científico publicado en 2015

Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?

artículo científico publicado en 2009

Isoforms of the Erythropoietin receptor in dopaminergic neurons of the Substantia Nigra

artículo científico publicado en 2016

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function

artículo científico publicado en 2011

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

artículo científico publicado en 2017

Missense mutations of human homeoboxes: A review

artículo científico publicado en 2001

Mitochondrial translocation of APE1 relies on the MIA pathway

artículo científico publicado en 2015

Modern strategies to identify new molecular targets for the treatment of liver diseases: The promising role of Proteomics and Redox Proteomics investigations.

artículo científico publicado en 2009

Molecular analysis of a human PAX6 homeobox mutant

artículo científico publicado en 2006

Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis.

artículo científico publicado en 2008

Molecular characterization of Pseudomonas aeruginosa 2NR degrading naphthalene

artículo científico publicado en 1999

Monoclonal antibodies against pools of mono- and polyacetylated peptides selectively recognize acetylated lysines within the context of the original antigen

artículo científico publicado en 2016

Monoclonal antibody detection of naphthalene dioxygenase from Pseudomonas aeruginosa 2NR

artículo científico publicado en 2000

New perspectives in cancer biology from a study of canonical and non-canonical functions of base excision repair proteins with a focus on early steps

artículo científico publicado en 2020

Nuclear localization of Galectin-3 in transformed thyroid cells: a role in transcriptional regulation

artículo científico publicado en 2003

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells

artículo científico publicado en 2012

Nucleophosmin delocalization in thyroid tumour cells

artículo científico publicado en 2011

Nucleophosmin is overexpressed in thyroid tumors.

artículo científico publicado en 2010

Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins.

artículo científico publicado en 2014

Nucleotide receptors stimulation by extracellular ATP controls Hsp90 expression through APE1/Ref-1 in thyroid cancer cells: a novel tumorigenic pathway

artículo científico publicado en 2006

Overoxidation of peroxiredoxins as an immediate and sensitive marker of oxidative stress in HepG2 cells and its application to the redox effects induced by ischemia/reperfusion in human liver

artículo científico publicado en 2005

Oxidized transthyretin in amniotic fluid as an early marker of preeclampsia

artículo científico publicado en 2007

PTEN and Egr-1 expression in thyroid proliferative lesions.

artículo científico publicado en 2004

Pax-8 protein levels regulate thyroglobulin gene expression

artículo científico publicado en 1998

Placental aging and oxidation damage in a tissue micro-array model: an immunohistochemistry study.

artículo científico publicado en 2016

Platinum Salts in Patients with Breast Cancer: A Focus on Predictive Factors

artículo científico publicado en 2019

Probing the dimeric structure of porcine aminoacylase 1 by mass spectrometric and modeling procedures.

artículo científico publicado en 2003

Proteomic analysis of human thyroid cell lines reveals reduced nuclear localization of Mn-SOD in poorly differentiated thyroid cancer cells

artículo científico publicado en 2005

Proteomic analysis of liver tissues subjected to early ischemia/reperfusion injury during human orthotopic liver transplantation

artículo científico publicado en 2006

Proteomic evaluation of core biopsy specimens from breast lesions

artículo científico publicado en 2004

RbAp48 is a target of nuclear factor-kappaB activity in thyroid cancer

artículo científico publicado en 2007

Redox effector factor-1 regulates the activity of thyroid transcription factor 1 by controlling the redox state of the N transcriptional activation domain

artículo científico publicado en 2002

Redox potential controls the structure and DNA binding activity of the paired domain

artículo científico publicado en 1998

Redox proteomics and immunohistology to study molecular events during ischemia-reperfusion in human liver

scientific article published on 01 July 2007

Redox state, oxidative stress, and molecular mechanisms of protective and toxic effects of bilirubin on cells.

artículo científico publicado en 2009

Ref-1 controls pax-8 DNA-binding activity

artículo científico publicado en 1998

Role of mutual interactions in the chemical and thermal stability of nucleophosmin NPM1 domains.

artículo científico publicado en 2012

Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin).

artículo científico publicado en 2013

SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements.

artículo científico publicado en 2013

Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma

article published in 2019

Serum APE1 as a predictive marker for platinum-based chemotherapy of non-small cell lung cancer patients

artículo científico publicado en 2016

Shotgun proteomics analysis reveals new unsuspected molecular effectors of nitrogen-containing bisphosphonates in osteocytes.

artículo científico publicado en 2011

Specific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell lines

artículo científico publicado en 2013

Structural defects of a Pax8 mutant that give rise to congenital hypothyroidism

artículo científico publicado en 1999

Structural defects of a Pax8 mutant that give rise to congenital hypothyroidism

artículo científico publicado en 1999

Structural studies on Pax-8 Prd domain/DNA complex

scientific article published on 01 April 2007

TRANSCRIPTION FACTORS AND CANCER. THE EXAMPLE OF PAX GENES.

artículo científico publicado en 1997

TSH controls Ref-1 nuclear translocation in thyroid cells

artículo científico publicado en 2000

Targeting DNA repair proteins for cancer treatment

artículo científico publicado en 2010

The PAX6 gene is activated by the basic helix-loop-helix transcription factor NeuroD/BETA2.

artículo científico publicado en 2003

The Solution Structure of DNA-free Pax-8 Paired Box Domain Accounts for Redox Regulation of Transcriptional Activity in the Pax Protein Family

artículo científico publicado en 2008

The intracellular localization of APE1/Ref-1: more than a passive phenomenon?

artículo científico publicado en 2005

The many functions of APE1/Ref-1: not only a DNA repair enzyme

artículo científico publicado en 2009

The neutrophil gelatinase-associated lipocalin (NGAL), a NF-kappaB-regulated gene, is a survival factor for thyroid neoplastic cells

artículo científico publicado en 2008

The prion protein is critical for DNA repair and cell survival after genotoxic stress

artículo científico publicado en 2014

The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate.

artículo científico publicado en 2014

The regulatory role of APE1 in epithelial-to-mesenchymal transition and in determining EGFR-TKI responsiveness in non-small-cell lung cancer

artículo científico publicado en 2018

Thyroid tumors: novel insights from proteomic studies.

artículo científico publicado en 2009

Topology of the thyroid transcription factor 1 homeodomain-DNA complex.

artículo científico publicado en 1999

Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis

artículo científico publicado en 2015

Transcriptional regulation of human sodium/iodide symporter gene: a role for redox factor-1.

artículo científico publicado en 2003

Transcriptome and proteome analysis of osteocytes treated with nitrogen-containing bisphosphonates

artículo científico publicado en 2009

Two novel NPM1 mutations in a therapy-responder AML patient

artículo científico publicado en 2010

Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment

artículo científico publicado en 2010

Unexpected phenotype of a typical NPM1 mutant.

artículo científico publicado en 2009

Unlike the Escherichia coli counterpart, archaeal RNase HII cannot process ribose monophosphate abasic sites and oxidized ribonucleotides embedded in DNA

artículo científico publicado en 2019

Unveiling the non-repair face of the Base Excision Repair pathway in RNA processing: A missing link between DNA repair and gene expression?

artículo científico publicado en 2017

[Letter to the Editor] Isolation of mitochondria is necessary for precise quantification of mitochondrial DNA damage in human carcinoma samples

artículo científico publicado en 2017

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