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Lista de obras de Gianni Sava

A Cationic [60] Fullerene Derivative Reduces Invasion and Migration of HT-29 CRC Cells in Vitro at Dose Free of Significant Effects on Cell Survival

A kinetic study of the chemical stability of the antimetastatic ruthenium complex NAMI-A.

artículo científico publicado en 2002

A novel retinoic/butyric hyaluronan ester for the treatment of acute promyelocytic leukemia: preliminary preclinical results.

artículo científico publicado en 2006

A review on usnic acid, an interesting natural compound

artículo científico publicado en 2002

Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A.

artículo científico publicado en 2004

Activity and inhibition by cytotoxic and antimetastatic drugs of cathepsin B-like cysteine proteinase in transplantable leukemias in mice

artículo científico publicado en 1987

Age Dependent Modification of the Metabolic Profile of the Tibialis Anterior Muscle Fibers in C57BL/6J Mice

scientific article published on 30 May 2020

Analysis of the cytotoxicity of synthetic antimicrobial peptides on mouse leucocytes: implications for systemic use.

artículo científico publicado en 2002

Anti-leukaemic action of RuCl2 (DMSO)4 isomers and prevention of brain involvement on P388 leukaemia and on P388/DDP subline

artículo científico publicado en 1993

Antiangiogenic properties of selected ruthenium(III) complexes that are nitric oxide scavengers.

artículo científico publicado en 2003

Antiinflammatory action of hydrosoluble dimethyltriazenes on the carrageenin-induced edema in guinea pigs

artículo científico publicado en 1985

Antimetastatic action and hematological toxicity of p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt and 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide used as prophylactic adjuvants to surgical tumor removal in mice bearing B16 melanoma.

artículo científico publicado en 1984

Antimetastatic action and toxicity on healthy tissues of Na[trans-RuCl4(DMSO)Im] in the mouse

article

Antimetastatic action of orally administered lysozyme in mice bearing Lewis lung carcinoma

scientific article published on 01 May 1988

Antimetastatic action of the prostacyclin analog Iloprost in the mouse

artículo científico publicado en 1989

Antimetastatic effects and tumor proteinase inhibition by spleen intracellular inhibitors of neutral proteinases

artículo científico publicado en 1981

Antimetastatic effects of N-diazoacetyl-glycine derivatives in C57BL mice

artículo científico publicado en 1977

Antimetastatic properties and DNA interactions of the novel class of dimeric Ru(III) compounds Na2[{trans-RuCl4(Me2SO)}2(μ-L)] (L=ditopic, non-chelating aromatic N-ligand). A preliminary investigation

scientific article published on 01 April 2000

Antineoplastic action of egg-white lysozyme on the growth of MCa mammary carcinoma and TLX5 lymphoma in the CBA mouse

artículo científico publicado en 1989

Antineoplastic action ofp-(3-methyl-1-triazeno)benzoic acid potassium salt, a monomethyl derivative of the antimetastatic compound DM-COOK

artículo científico publicado en 1991

Antineoplastic activity and toxicity of an organometallic complex of ruthenium(II) in comparison with cis-PDD in mice bearing solid malignant neoplasms

article

Antineoplastic activity of planar rhodium(I) complexes in mice bearing Lewis lung carcinoma and P388 leukemia

artículo científico publicado en 1985

Antineoplastic effect of mer-trichlorobisdimethylsulphoxideaminorutheniumIII against murine tumors: comparison with cisplatin and with ImH[RuIm2Cl4].

artículo científico publicado en 1991

Antineoplastic effects of egg-white lysozyme in mice bearing solid metastasizing tumors

artículo científico publicado en 1986

Antitumor action of rhodium (I) and iridium (I) complexes

artículo científico publicado en 1978

Antitumor action of two rhodium and ruthenium complexes in comparison with cis-diamminedichloroplatinum(II).

artículo científico publicado en 1977

Antitumor activity of N-diazoacetyl derivatives of glycine and phenylalanine against P388 leukemia and B16 melanoma in mice

scientific article published on 01 January 1982

Antitumor and antimetastatic activity of the immunoadjuvant peptidoglycan monomer PGM in mice bearing MCa mammary carcinoma

artículo científico publicado en 1984

Antitumor and antimetastatic effects of benzenoid triazenes in mice bearing lewis lung carcinoma

artículo científico publicado en 1980

Antitumor effects of GANU and other nitrosourea derivatives against transplantable leukemias and solid tumors in mice

artículo científico publicado en 1983

Antitumor effects of rhodium(I), iridium(I) and ruthenium(II) complexes in comparison with cis-dichlorodiammino platinum(II) in mice bearing Lewis lung carcinoma

artículo científico publicado en 1983

Antitumour properties of dimethylsulphoxide ruthenium(II) complexes in the Lewis lung carcinoma system

artículo científico publicado en 1989

Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir

artículo científico publicado en 2004

Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates

artículo científico publicado en 2011

Biochemical and biological characteristics of leucocyte proteinase inhibitors

artículo científico publicado en 1982

Biological role of adduct formation of the ruthenium(III) complex NAMI-A with serum albumin and serum transferrin.

artículo científico publicado en 2003

Blood concentration and toxicity of the antimetastasis agent NAMI-A following repeated intravenous treatment in mice

artículo científico publicado en 2000

Blood levels of ruthenium following repeated treatments with the antimetastatic compound NAMI-A in healthy beagle dogs

artículo científico publicado en 2000

CDK1 hyperphosphorylation maintenance drives the time-course of G2-M cell cycle arrest after short treatment with NAMI-A in Kb cells.

artículo científico publicado en 2012

Can peptides be orally-delivered in crustaceans? The case study of the Crustacean Hyperglycaemic Hormone in Procambarus clarkii

article

Chemical and Molecular Approach to Tumor Metastases.

artículo científico publicado en 2018

Chemical xenogenization of murine lymphoma cells with triazene derivatives: immunotoxicological studies

artículo científico publicado en 1984

Cocultures of metastatic and host immune cells: selective effects of NAMI-A for tumor cells

artículo científico publicado en 2004

Colorectal Cancer Metastases Settle in the Hepatic Microenvironment Through α5β1 Integrin.

artículo científico publicado en 2015

Comparison of the effects of the antimetastatic compound ImH[trans-RuCl4(DMSO)Im] (NAMI-A) on the arthritic rat and on MCa mammary carcinoma in mice

scientific article published on 01 January 1998

Cytofluorimetric analysis of gut-intraepithelial and mesenteric lymph node lymphocytes of tumour bearing mice fed with egg-white lysozyme

scientific article published on 01 January 1996

DTIC and its derivatives: cytotoxic or antimetastatic drugs?

artículo científico publicado en 1985

Development of a LC method for pharmaceutical quality control of the antimetastatic ruthenium complex NAMI-A.

artículo científico publicado en 2003

Development of ruthenium antitumor drugs that overcome multidrug resistance mechanisms

artículo científico publicado en 2007

Distinct effects of dinuclear ruthenium(III) complexes on cell proliferation and on cell cycle regulation in human and murine tumor cell lines

artículo científico publicado en 2003

Down-regulation of tumour gelatinase/inhibitor balance and preservation of tumour endothelium by an anti-metastatic ruthenium complex

scientific article published on 01 September 1996

Drug control of solid tumour metastases: a critical view.

artículo científico publicado en 1999

Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.

artículo científico publicado en 2003

Effects of DTIC, DM-COOK and ICRF-159 on the number of circulating Lewis lung carcinoma cells detected by flow cytometry

artículo científico publicado en 1984

Effects of L-(adamant-2-yl)glycyl-L-alanyl-d-isoglutamine on the antitumor action of cyclophosphamide, 5-fu, Cisplatin and dacarbazine on advanced carcinomas of the mouse

artículo científico publicado en 1994

Effects of N-diazoacetyl-glycine amide on the pool of 5-phosphoribosyl 1-pyrophosphate in Ehrlich ascites tumour cells

artículo científico publicado en 1976

Effects of NAMI-A and some related ruthenium complexes on cell viability after short exposure of tumor cells.

artículo científico publicado en 2000

Effects of Two Fullerene Derivatives on Monocytes and Macrophages.

artículo científico publicado en 2015

Effects of an inducer and an inhibitor of hepatic metabolism on the antitumor action of dimethyltriazenes

artículo científico publicado en 1988

Effects of antimetastatic dimethyltriazenes in mice bearing Lewis lung carcinoma lines with different metastatic potential.

artículo científico publicado en 1984

Effects of antimetastatic, antiinvasive and cytotoxic agents on the growth and spread of transplantable leukemias in mice

artículo científico publicado en 1987

Effects of dimethyltriazenes combined with surgery and non-specific immunotherapy in mice bearing Lewis lung carcinoma lines

artículo científico publicado en 1985

Effects of isomeric aryldimethyltriazenes on lewis lung carcinoma growth and metastases in mice

artículo científico publicado en 1983

Effects of lysozyme on spleen and lungs in mice with Lewis lung carcinoma

artículo científico publicado en 1988

Effects of p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt on leukemic infiltration of brain and liver in mice bearing P388 leukemia.

artículo científico publicado en 1984

Effects of postsurgical immunotherapy with PGM in mice bearing Lewis lung carcinoma treated with p-(3,3-dimethyl-1-triazeno) benzoic acid potassium salt

artículo científico publicado en 1985

Effects of ruthenium complexes on experimental tumors: irrelevance of cytotoxicity for metastasis inhibition

artículo científico publicado en 1995

Effects of some ruthenium chelates on MCa mammary carcinoma and on TLX5 lymphoma in mice

artículo científico publicado en 1993

Effects of the Ru(III) complexes [mer-RuCl3(DMSO)2Im]degrees and Na[trans-RuCl4(DMSO)Im] on solid mouse tumors

artículo científico publicado en 1992

Effects of the ruthenium-based drug NAMI-A on the roles played by TGF-β1 in the metastatic process

artículo científico publicado en 2015

Effects of trans-RuCl2(DMSO)4 on B16 melanoma in mice

scientific article published on 01 November 1989

Effects of two pyridinalalkyliminerhodium(I) complexes in mice bearing MCa mammary carcinoma

scientific article published on 01 January 1989

Efficacy of 5-FU Combined to Na[trans-RuCl(4)(DMSO)Im], A Novel Selective Antimetastatic Agent, on the Survival Time of Mice With P388 Leukemia, P388/DDP subline and MCa Mammary Carcinoma.

artículo científico publicado en 1995

Electrochemical measurements confirm the preferential bonding of the antimetastatic complex [ImH][RuCl(4)(DMSO)(Im)] (NAMI-A) with proteins and the weak interaction with nucleobases

artículo científico publicado en 2004

Evidence for host-mediated antitumor effects of lysozyme in mice bearing the MCa mammary carcinoma

artículo científico publicado en 1988

Features and full reversibility of the renal toxicity of the ruthenium-based drug NAMI-A in mice ⬇️

artículo científico publicado el 26 de septiembre de 2012

Free exchange across cells, and echistatin-sensitive membrane target for the metastasis inhibitor NAMI-A (imidazolium trans-imidazole dimethyl sulfoxide tetrachlororuthenate) on KB tumor cells.

artículo científico publicado en 2004

Half-sandwich Ru II[9]aneS3 complexes structurally similar to antitumor-active organometallic piano-stool compounds: preparation, structural characterization and in vitro cytotoxic activity

artículo científico publicado en 2008

Hemostasis and mechanism of action of selective antimetastatic drugs in mice bearing Lewis lung carcinoma

artículo científico publicado en 1984

Human recombinant lysozyme downregulates advanced glycation endproduct-induced interleukin-6 production and release in an in-vitro model of human proximal tubular epithelial cells.

artículo científico publicado en 2014

Hyaluronic-acid butyric esters as promising antineoplastic agents in human lung carcinoma: a preclinical study

artículo científico publicado en 2004

Identification and Characterization of a Novel Family of Cysteine-Rich Peptides (MgCRP-I) from Mytilus galloprovincialis

artículo científico publicado en 2015

Immunogenic changes of murine lymphoma cells following in vitro treatment with aryl-triazene derivatives

artículo científico publicado en 1984

Immunotherapy of lewis lung carcinoma with hydrosoluble peptidoglycan monomer (PGM)

artículo científico publicado en 1983

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

artículo científico publicado en 2005

In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin

artículo científico publicado en 1999

In vitro down regulation of ICAM-1 and E-cadherin and in vivo reduction of lung metastases of TS/A adenocarcinoma by a lysozyme derivative.

artículo científico publicado en 1999

In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model.

artículo científico publicado en 2009

Increase of tumour infiltrating lymphocytes in mice treated with antimetastatic doses of NAMI-A

artículo científico publicado en 2000

Infiltration of liver and brain by tumor cells in leukemic mice: prevention by dimethyltriazenes and cyclophosphamide

artículo científico publicado en 1984

Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A.

artículo científico publicado en 2002

Influence of the anionic ligands on the anticancer activity of Ru(II)-dmso complexes: Kinetics of aquation and in vitro cytotoxicity of new dicarboxylate compounds in comparison with their chloride precursors

artículo científico publicado en 2007

Influence of the binding of reduced NAMI-A to human serum albumin on the pharmacokinetics and biological activity.

artículo científico publicado en 2015

Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion.

artículo científico publicado en 2005

Inhibition of adhesion, migration and of α5β1 integrin in the HCT-116 colorectal cancer cells treated with the ruthenium drug NAMI-A.

artículo científico publicado en 2016

Inhibition of endothelial cell functions and of angiogenesis by the metastasis inhibitor NAMI-A.

artículo científico publicado en 2002

Inhibition of hepatocellular carcinomas in vitro and hepatic metastases in vivo in mice by the histone deacetylase inhibitor HA-But

artículo científico publicado en 2004

Inhibition of human pancreatic cell line MIA PaCa2 proliferation by HA-But, a hyaluronic butyric ester: a preliminary report

artículo científico publicado en 2008

Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation

artículo científico publicado en 2002

Inhibitory Effects of the Ruthenium Complex KP1019 in Models of Mammary Cancer Cell Migration and Invasion.

artículo científico publicado en 2009

Intratumoral NAMI-A treatment triggers metastasis reduction, which correlates to CD44 regulation and tumor infiltrating lymphocyte recruitment

artículo científico publicado en 2004

Investigation on the oxidative N-demethylation of aryl triazenes in vitro.

artículo científico publicado en 1975

Isolation of a murine metastatic cell line and preliminary test of sensitivity to the anti-metastasis agent NAMI-A.

artículo científico publicado en 2001

Kinetic investigation of the aqueous stability and antitumor activity of a hydrosoluble diaryltriazene, AVIS, related to the antimetastatic agent DM-COOK.

artículo científico publicado en 1990

Lack of In vitro cytotoxicity, associated to increased G(2)-M cell fraction and inhibition of matrigel invasion, may predict In vivo-selective antimetastasis activity of ruthenium complexes

artículo científico publicado en 2000

Linking the future of anticancer metal-complexes to the therapy of tumour metastases

artículo científico

Lysosomal enzyme inhibitors and antimetastatic activity in the mouse

artículo científico publicado en 1977

Lysozyme induced recovery of the response to cona on mononuclear-cells harvested from mice bearing mca mammary-carcinoma

artículo científico publicado en 1994

Lysozyme-Induced Transcriptional Regulation of TNF-α Pathway Genes in Cells of the Monocyte Lineage ⬇️

artículo científico publicado en 2019

Mechanism of the antileukemic effects of 1-p-carboxamidophenyl-3,3-dimethyltriazene and its in vitro metabolites.

artículo científico publicado en 1982

Mechanism of the antimetastatic action of N-diazoacetylglycinamide in mice bearing lewis lung carcinoma

artículo científico publicado en 1980

Mechanism of the antimetastatic action of dimethyltriazenes

artículo científico publicado en 1979

Mechanism of the antineoplastic action of lysozyme: evidence for host mediated effects

artículo científico publicado en 1989

Metabolism and mechanism of the antileukemic action of isomeric aryldimethyltriazenes.

artículo científico publicado en 1982

Metal based drugs restyled and resumed

artículo científico publicado en 2007

Metal complexes of ruthenium: a potential class of selective anticancer drugs.

artículo científico publicado en 1991

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase − The Guardian Angel of DNA ⬇️

artículo científico publicado el 3 de marzo de 2011

Metal-based antitumour drugs in the post genomic era.

artículo científico publicado en 2006

Metal-based antitumour drugs in the post-genomic era: what comes next? ⬇️

artículo científico publicado el 4 de julio de 2011

Methodologic problems encountered in the assay of proteinases in Lewis lung carcinoma, a mouse metastasizing tumor

artículo científico publicado en 1982

Microencapsulation of bioactive principles with an airless spray-gun suitable for processing high viscous solutions

artículo científico publicado en 2013

Modification of cell cycle and viability of TLX5 lymphoma in vitro by sulfoxide-ruthenium compounds and cisplatin detected by flow cytometry

artículo científico publicado en 1998

Modification of the growth of mca mammary-carcinoma of cba mouse by new adamantylpeptides

artículo científico publicado en 1993

Modulation of the metastatic progression of breast cancer with an organometallic ruthenium compound.

artículo científico publicado en 2008

Molecular structure, solution chemistry and biological properties of the novel [ImH][trans-IrCl(4)(Im)(DMSO)], (I) and of the orange form of [(DMSO)(2)H][trans-IrCl(4)(DMSO)(2)], (II), complexes

artículo científico publicado en 2003

Mutagenic activity of the dacarbazine analog p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt in bacterial cells

artículo científico publicado en 1986

Na[trans-RuCl4(DMSO)Im], a metal complex of ruthenium with antimetastatic properties

artículo científico publicado en 1992

Neutral proteinase inhibitors and antimetastatic effects in mice

artículo científico publicado en 1980

Observations on the antimetastatic action of lysozyme in mice bearing Lewis lung carcinoma

artículo científico publicado en 1991

Observations on the “in vitro” oxidative N-demethylation of 4-(3,3-dimetryl-1-triazeno)-imidazole-5-carboxamide (DIC, NSC 45388)

artículo científico publicado en 1976

Oral poly(ethylene glycol)-conjugated human recombinant lysozyme control of lung metastases in mice

artículo científico publicado en 2008

Orally administered microencapsulated lysozyme downregulates serum AGE and reduces the severity of early-stage diabetic nephropathy

artículo científico publicado en 2008

Paracrine effects of IL-4 transfection on TS/A adenocarcinoma cells mediate reduced in vivo growth

artículo científico publicado en 1999

Pharmaceutical development of a parenteral lyophilized formulation of the antimetastatic ruthenium complex NAMI-A.

artículo científico publicado en 2002

Pharmacological Activities of Ruthenium Complexes Related to Their NO Scavenging Properties

artículo científico publicado en 2016

Pharmacological Effects of the Ruthenium Complex NAMI-A Given Orally to CBA Mice With MCa Mammary Carcinoma.

artículo científico publicado en 2001

Pharmacological aspects and therapeutic applications of lysozymes

artículo científico publicado en 1996

Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex

artículo científico publicado en 1998

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

artículo científico publicado en 2014

Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A.

artículo científico publicado en 2002

Platinum(II) complexes with antitumoral/antiviral aromatic heterocycles: effect of glutathione upon in vitro cell growth inhibition

artículo científico publicado en 2005

Preclinical combination therapy of the investigational drug NAMI-A(+) with doxorubicin for mammary cancer

artículo científico publicado en 2014

Primary tumor growth and formation of spontaneous lung metastases in mice bearing Lewis carcinoma treated with proteinase inhibitors

artículo científico publicado en 1984

Primary tumor, lung and kidney retention and antimetastasis effect of NAMI-A following different routes of administration

artículo científico publicado en 2003

Profiling the molecular mechanism of fullerene cytotoxicity on tumor cells by RNA-seq

artículo científico publicado en 2013

Prophylactic antimetastatic treatment with aryldimethyltriazenes as adjuvants to surgical tumor removal in mice bearing Lewis lung carcinoma.

artículo científico publicado en 1982

Proteinases and proteinase inhibition by cytotoxic and antimetastatic drugs in transplantable solid metastasizing tumors in mice

artículo científico publicado en 1985

RNA-seq analysis of the whole transcriptome of MDA-MB-231 mammary carcinoma cells exposed to the antimetastatic drug NAMI-A.

artículo científico publicado en 2015

Reduction of B16 melanoma metastases by oral administration of egg-white lysozyme

artículo científico publicado en 1989

Reduction of Lung Metastases by Na[trans-RuCl(4)(DMSO)Im] is not Coupled With the Induction of Chemical Xenogenization.

artículo científico publicado en 1996

Reduction of MCa mammary carcinoma in mice fed with egg-white lysozyme

scientific article published on 01 September 1990

Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro tumour invasion.

artículo científico publicado en 2004

Role of host responses in the drug treatment of metastasis

article

Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs ⬇️

artículo científico publicado el 21 de agosto de 2011

Ruthenium antimetastatic agents

artículo científico publicado en 2004

Ruthenium(III) dimethyl sulfoxide pyridinehydroxamic acid complexes as potential antimetastatic agents: synthesis, characterisation and in vitro pharmacological evaluation

artículo científico publicado en 2008

Ruthenium-based NAMI-A type complexes with in vivo selective metastasis reduction and in vitro invasion inhibition unrelated to cell cytotoxicity.

artículo científico publicado en 2002

Ruthenium-based compounds and tumour growth control (review).

artículo científico publicado en 2000

Ruthenium-porphyrin conjugates with cytotoxic and phototoxic antitumor activity

artículo científico publicado en 2010

Selective antimetastatic drugs (review).

artículo científico publicado en 1981

Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma.

artículo científico publicado en 1981

Solution, solid state and biological characterization of ruthenium(III)-DMSO complexes with purine base derivatives

artículo científico publicado en 2004

Some further characteristics of endogenous proteinase inhibitors

scientific article published on 01 January 1982

Stimulation of GALT and activation of mesenteric lymph node lymphocytes by a modified lysozyme in CBA mice with MCa mammary carcinoma

artículo científico publicado en 1996

Structure-dependent in vitro cytotoxicity of the isomeric complexes [Ru(L)2Cl2] (L= o-tolylazopyridine and 4-methyl-2-phenylazopyridine) in comparison to [Ru(azpy)2Cl2].

artículo científico publicado en 2004

Study of a potential drug delivery system based on carbon nanoparticles: effects of fullerene derivatives in MCF7 mammary carcinoma cells

Synthesis and antitumor activity of hydrosoluble analogs of p-(3,3-dimethyl-1-triazeno) benzoic acid potassium salt

artículo científico publicado en 1991

Synthesis and chemical-pharmacological characterization of the antimetastatic NAMI-A-type Ru(III) complexes (Hdmtp)[trans-RuCl4(dmso-S)(dmtp)], (Na)[trans-RuCl4(dmso-S)(dmtp)], and [mer-RuCl3(H2O)(dmso-S)(dmtp)] (dmtp = 5,7-dimethyl[1,2,4]triazolo[1

artículo científico publicado en 2004

Synthesis of l-Aryl-3-formyl-3-methyltriazenes, Potential Metabolites of l-Ary1-3,3-dimethyltriazenes

artículo científico publicado en 1980

Synthesis, Characterization, and in Vitro Evaluation of Novel Ruthenium(II) η6-Arene Imidazole Complexes

artículo científico publicado en 2006

Synthesis, catalytic properties and biological activity of new water soluble ruthenium cyclopentadienyl PTA complexes [(C5R5)RuCl(PTA)2] (R = H, Me; PTA = 1,3,5-triaza-7-phosphaadamantane).

artículo científico publicado en 2003

Synthesis, characterization and biological activity of copper complexes with pyridoxal thiosemicarbazone derivatives. X-ray crystal structure of three dimeric complexes

artículo científico publicado en 2004

Synthetic thymic fraction 5: effects of high dose administration on circulating lymphocytes in patients

artículo científico publicado en 1996

TGFbeta1 regulation and collagen-release-independent connective tissue re-modelling by the ruthenium complex NAMI-A in solid tumours

artículo científico publicado en 2004

Targeted therapy vs. DNA-adduct formation-guided design: thoughts about the future of metal-based anticancer drugs ⬇️

artículo científico publicado el 22 de mayo de 2012

The Differential Distribution of RAPTA-T in Non-Invasive and Invasive Breast Cancer Cells Correlates with Its Anti-Invasive and Anti-Metastatic Effects.

artículo científico publicado en 2017

The anti-metastatic agent imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway

artículo científico publicado en 2002

The antimetastatic drug NAMI-A potentiates the phenylephrine-induced contraction of aortic smooth muscle cells and induces a transient increase in systolic blood pressure.

artículo científico publicado en 2015

The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: an NMR evaluation

artículo científico publicado en 2004

The role of cisplatin and NAMI-A plasma-protein interactions in relation to combination therapy.

artículo científico publicado en 2006

Treatment of metastases of solid mouse tumours by NAMI-A: comparison with cisplatin, cyclophosphamide and dacarbazine

artículo científico publicado en 1999

Treatment of residual metastases with Na[trans-RuCl4 (DMSO)lm] and ruthenium uptake by tumor cells

artículo científico publicado en 1996

Tumor cell metastasis and surface neutral proteinase: effects of antimetastatic and antitumor drugs.

artículo científico publicado en 1985

Tumour cell uptake G2-M accumulation and cytotoxicity of NAMI-A on TS/A adenocarcinoma cells

artículo científico publicado en 2001

Tumour cell uptake of the metastasis inhibitor ruthenium complex NAMI-A and its in vitro effects on KB cells

artículo científico publicado en 2002

Tuning the hydrophobicity of ruthenium(II)-arene (RAPTA) drugs to modify uptake, biomolecular interactions and efficacy

artículo científico publicado en 2007

Validated method for the determination of the novel organo-ruthenium anticancer drug NAMI-A in human biological fluids by Zeeman atomic absorption spectrometry

artículo científico publicado en 2001

[The clinical risk management: an initial experience of incident reporting in a surgical department]

artículo científico publicado en 2010

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