Lista de obras - Adelaide Fernandes - Dominio Público Uruguay

Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis

artículo científico publicado en 2019

Anti-inflammatory effect of rosmarinic acid and an extract of Rosmarinus officinalis in rat models of local and systemic inflammation

artículo científico publicado en 2014

Apoptosis and impairment of neurite network by short exposure of immature rat cortical neurons to unconjugated bilirubin increase with cell differentiation and are additionally enhanced by an inflammatory stimulus

artículo científico publicado en 2007

Astrocyte reactivity to unconjugated bilirubin requires TNF-α and IL-1β receptor signaling pathways

scientific journal article

Automated analysis of NeuronJ tracing data

artículo científico publicado en 2009

Bilirubin as a determinant for altered neurogenesis, neuritogenesis, and synaptogenesis

artículo científico publicado en 2009

Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid

artículo científico publicado en 2007

Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation state

artículo científico publicado en 2006

Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cells

artículo científico publicado en 2005

Bilirubin-induced neural impairment: a special focus on myelination, age-related windows of susceptibility and associated co-morbidities

artículo científico

Biological risks for neurological abnormalities associated with hyperbilirubinemia.

artículo científico publicado en 2009

Contribution of inflammatory processes to nerve cell toxicity by bilirubin and efficacy of potential therapeutic agents

scientific article published on January 2009

Cross-talk between neurons and astrocytes in response to bilirubin: adverse secondary impacts

artículo científico publicado en 2014

Cross-talk between neurons and astrocytes in response to bilirubin: early beneficial effects

artículo científico publicado en 2013

Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS.

artículo científico publicado en 2004

Directing mouse embryonic neurosphere differentiation toward an enriched neuronal population

artículo científico publicado en 2014

Dissociated primary nerve cell cultures as models for assessment of neurotoxicity

artículo científico publicado en 2005

Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an Early Stage

artículo científico publicado en 2017

Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities.

artículo científico publicado en 2017

ER stress, mitochondrial dysfunction and calpain/JNK activation are involved in oligodendrocyte precursor cell death by unconjugated bilirubin

artículo científico publicado en 2012

Elevated levels of bilirubin and long-term exposure impair human brain microvascular endothelial cell integrity

artículo científico publicado en 2011

Erythropoietin reduces acute lung injury and multiple organ failure/dysfunction associated to a scald-burn inflammatory injury in the rat.

artículo científico publicado en 2015

Evidence of tricellulin expression by immune cells, particularly microglia

article

Features of bilirubin-induced reactive microglia: from phagocytosis to inflammation.

artículo científico publicado en 2010

Glycoursodeoxycholic Acid and Interleukin-10 Modulate the Reactivity of Rat Cortical Astrocytes to Unconjugated Bilirubin

artículo científico publicado en 2007

Impaired oligodendrogenesis and myelination by elevated S100B levels during neurodevelopment

artículo científico publicado en 2017

Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubin

artículo científico publicado en 2006

Influence of hypoxia and ischemia preconditioning on bilirubin damage to astrocytes

artículo científico publicado en 2007

Inhibition of glycogen synthase kinase-3β attenuates organ injury and dysfunction associated with liver ischemia-reperfusion and thermal injury in the rat.

artículo científico publicado en 2015

Interventions for age-related diseases: Shifting the paradigm

artículo científico publicado en 2016

MAPKs are key players in mediating cytokine release and cell death induced by unconjugated bilirubin in cultured rat cortical astrocytes

artículo científico publicado en 2007

Microglia and inflammation: conspiracy, controversy or control?

artículo científico publicado en 2014

Microglia change from a reactive to an age-like phenotype with the time in culture

artículo científico publicado en 2014

Microglial Phagocytosis-Rational but Challenging Therapeutic Target in Multiple Sclerosis

artículo científico publicado en 2020

Modelling physical resilience in ageing mice

article

N-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicity

artículo científico publicado en 2010

Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10.

artículo científico publicado en 2012

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

artículo científico publicado en 2015

Neuroprotective effects of erythropoietin pretreatment in a rodent model of transient middle cerebral artery occlusion

artículo científico publicado en 2014

Oligodendrocyte Development and Myelination in Neurodevelopment: Molecular Mechanisms in Health and Disease

artículo científico

Peptidomimetic β-Secretase Inhibitors Comprising a Sequence of Amyloid-β Peptide for Alzheimer's Disease

artículo científico publicado en 2015

Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin

artículo científico publicado en 2011

Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-α inhibitors

scientific journal article

Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia

artículo científico publicado en 2015

Role of multidrug resistance-associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin

scientific journal article

S100B as a Potential Biomarker and Therapeutic Target in Multiple Sclerosis

artículo científico publicado en 2015

Secretome from SH-SY5Y APP Swe cells trigger time-dependent CHME3 microglia activation phenotypes, ultimately leading to miR-21 exosome shuttling

article by Adelaide Fernandes et al published May 2018 in Biochimie

Selective vulnerability of rat brain regions to unconjugated bilirubin

artículo científico publicado en 2011

Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects

artículo científico publicado en 2015

Temporal oligodendrocyte lineage progression: in vitro models of proliferation, differentiation and myelination.

artículo científico

Topical gels of etofenamate: in vitro and in vivo evaluation

artículo científico publicado en 2014

Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

article

Tricellulin expression in brain endothelial and neural cells

artículo científico publicado en 2012

Unconjugated bilirubin activates and damages microglia

artículo científico publicado en 2006

Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells

artículo científico publicado en 2007

Unconjugated bilirubin restricts oligodendrocyte differentiation and axonal myelination

artículo científico publicado en 2012

Lista de obras de Adelaide Fernandes

Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis

Anti-inflammatory effect of rosmarinic acid and an extract of Rosmarinus officinalis in rat models of local and systemic inflammation

Apoptosis and impairment of neurite network by short exposure of immature rat cortical neurons to unconjugated bilirubin increase with cell differentiation and are additionally enhanced by an inflammatory stimulus

Astrocyte reactivity to unconjugated bilirubin requires TNF-α and IL-1β receptor signaling pathways

Automated analysis of NeuronJ tracing data

Bilirubin as a determinant for altered neurogenesis, neuritogenesis, and synaptogenesis

Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid

Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation state

Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cells

Bilirubin-induced neural impairment: a special focus on myelination, age-related windows of susceptibility and associated co-morbidities

Biological risks for neurological abnormalities associated with hyperbilirubinemia.

Contribution of inflammatory processes to nerve cell toxicity by bilirubin and efficacy of potential therapeutic agents

Cross-talk between neurons and astrocytes in response to bilirubin: adverse secondary impacts

Cross-talk between neurons and astrocytes in response to bilirubin: early beneficial effects

Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS.

Directing mouse embryonic neurosphere differentiation toward an enriched neuronal population

Dissociated primary nerve cell cultures as models for assessment of neurotoxicity

Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an Early Stage

Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities.

ER stress, mitochondrial dysfunction and calpain/JNK activation are involved in oligodendrocyte precursor cell death by unconjugated bilirubin

Elevated levels of bilirubin and long-term exposure impair human brain microvascular endothelial cell integrity

Erythropoietin reduces acute lung injury and multiple organ failure/dysfunction associated to a scald-burn inflammatory injury in the rat.

Evidence of tricellulin expression by immune cells, particularly microglia

Features of bilirubin-induced reactive microglia: from phagocytosis to inflammation.

Glycoursodeoxycholic Acid and Interleukin-10 Modulate the Reactivity of Rat Cortical Astrocytes to Unconjugated Bilirubin

Impaired oligodendrogenesis and myelination by elevated S100B levels during neurodevelopment

Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubin

Influence of hypoxia and ischemia preconditioning on bilirubin damage to astrocytes

Inhibition of glycogen synthase kinase-3β attenuates organ injury and dysfunction associated with liver ischemia-reperfusion and thermal injury in the rat.

Interventions for age-related diseases: Shifting the paradigm

MAPKs are key players in mediating cytokine release and cell death induced by unconjugated bilirubin in cultured rat cortical astrocytes

Microglia and inflammation: conspiracy, controversy or control?

Microglia change from a reactive to an age-like phenotype with the time in culture

Microglial Phagocytosis-Rational but Challenging Therapeutic Target in Multiple Sclerosis

Modelling physical resilience in ageing mice

N-methyl-aspartate receptor and neuronal nitric oxide synthase activation mediate bilirubin-induced neurotoxicity

Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10.

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

Neuroprotective effects of erythropoietin pretreatment in a rodent model of transient middle cerebral artery occlusion

Oligodendrocyte Development and Myelination in Neurodevelopment: Molecular Mechanisms in Health and Disease

Peptidomimetic β-Secretase Inhibitors Comprising a Sequence of Amyloid-β Peptide for Alzheimer's Disease

Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin

Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-α inhibitors

Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia

Role of multidrug resistance-associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin

S100B as a Potential Biomarker and Therapeutic Target in Multiple Sclerosis

Secretome from SH-SY5Y APP Swe cells trigger time-dependent CHME3 microglia activation phenotypes, ultimately leading to miR-21 exosome shuttling

Selective vulnerability of rat brain regions to unconjugated bilirubin

Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects

Temporal oligodendrocyte lineage progression: in vitro models of proliferation, differentiation and myelination.

Topical gels of etofenamate: in vitro and in vivo evaluation

Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

Tricellulin expression in brain endothelial and neural cells

Unconjugated bilirubin activates and damages microglia

Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells

Unconjugated bilirubin restricts oligodendrocyte differentiation and axonal myelination