Lista de obras - Elisabeth Davioud-Charvet

1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agents

artículo científico publicado en 2013

18-Vinyldeoxycorticosterone: a potent inhibitor of the bovine cytochrome P -450 11β

artículo científico publicado en 1998

2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity.

artículo científico publicado en 2001

5-substituted tetrazoles as bioisosteres of carboxylic acids. Bioisosterism and mechanistic studies on glutathione reductase inhibitors as antimalarials

artículo científico publicado en 2004

A General Approach to the Synthesis of Polyamine Linked-Monoindolylmaleimides, a New Series of Trypanothione Reductase Inhibitors

artículo científico publicado en 1998

A Mild and Versatile Friedel-Crafts Methodology for the Diversity-Oriented Synthesis of Redox-Active 3-Benzoylmenadiones with Tunable Redox Potentials

scientific article published on 28 January 2020

A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs

artículo científico publicado en 2016

A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme

artículo científico publicado en 2006

A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assay

artículo científico publicado en 2017

A novel mechanism for inhibition of HIV-1 reverse transcriptase

artículo científico publicado en 2002

A physico-biochemical study on potential redox-cyclers as antimalarial and anti-schistosomal drugs.

artículo científico publicado en 2012

A plant-derived flavonoid inhibits entry of all HCV genotypes into human hepatocytes

artículo científico publicado en 2012

A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline.

artículo científico publicado en 2001

A sugar-modified phosphole gold complex with antiproliferative properties acting as a thioredoxin reductase inhibitor in MCF-7 cells

artículo científico publicado en 2008

An improved synthesis of 18-norandrost-4-ene-3,17-dione

scientific article published on 01 March 1993

AntiMalarial Mode of Action (AMMA) Database: Data Selection, Verification and Chemical Space Analysis

scholarly article by Pavel Sidorov et al published 11 May 2018 in Molecular Informatics

Antiglioma activity of GoPI-sugar, a novel gold(I)-phosphole inhibitor: chemical synthesis, mechanistic studies, and effectiveness in vivo.

artículo científico publicado en 2014

Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats

artículo científico publicado en 2015

Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker

artículo científico publicado en 2009

Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum

artículo científico publicado en 2008

Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA.

artículo científico publicado en 2010

Antimalarial, antitrypanosomal, and antileishmanial activities and cytotoxicity of bis(9-amino-6-chloro-2-methoxyacridines): influence of the linker

artículo científico publicado en 2000

Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase

scientific article published on 10 December 2019

Antiplasmodial activity and cytotoxicity of bis-, tris-, and tetraquinolines with linear or cyclic amino linkers

artículo científico publicado en 2001

Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides.

artículo científico publicado en 2002

Arylmethylamino steroids as antiparasitic agents

artículo científico publicado en 2017

Author Correction: Arylmethylamino steroids as antiparasitic agents

scientific article published on 08 July 2019

Bromination studies of the 2,3-dimethylnaphthazarin core allowing easy access to naphthazarin derivatives

artículo científico publicado en 2001

Comparison of the inhibition of human and Trypanosoma cruzi prolyl endopeptidases

artículo científico publicado en 2002

Correction: Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target

artículo científico publicado en 2007

Double-drug development against antioxidant enzymes from Plasmodium falciparum

artículo científico publicado en 2003

Electrochemical properties of substituted 2-methyl-1,4-naphthoquinones: redox behavior predictions

artículo científico publicado en 2014

Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials

artículo científico publicado en 2022

Evidence for the co-existence of glutathione reductase and trypanothione reductase in the non-trypanosomatid Euglenozoa: Euglena gracilis Z

artículo científico publicado en 1999

Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase

artículo científico publicado en 2012

Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites

artículo científico publicado en 2011

Glutathione-dependent activities of Trypanosoma cruzi p52 makes it a new member of the thiol:disulphide oxidoreductase family

artículo científico publicado en 1997

High Sensitivity to Auxin is a Common Feature of Hairy Root

artículo científico publicado en 1990

In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids.

artículo científico publicado en 2016

Interactions of the antimalarial drug methylene blue with methemoglobin and heme targets in Plasmodium falciparum: a physico-biochemical study

artículo científico publicado en 2012

Investigating the mode of action of the redox-active antimalarial drug plasmodione using the yeast model

scientific article published on 22 June 2019

Iridoids of Guyanese Species of Stigmaphyllon

scientific article published on 01 February 1985

Iron(iii) coordination properties of ladanein, a flavone lead with a broad-spectrum antiviral activity

Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate

artículo científico publicado en 2005

Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity

artículo científico publicado en 2003

Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase

artículo científico publicado en 2005

New spermine and spermidine derivatives as potent inhibitors of Trypanosoma cruzi Trypanothione Reductase

scientific article published on 01 July 1997

New steroidal diazo ketones as potential photoaffinity labeling reagents for the mineralocorticoid receptor: synthesis and biological activities.

artículo científico publicado en 1996

Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties

artículo científico publicado en 2017

Photoaffinity labelling of the human mineralocorticoid receptor with steroids having a reactive group at position 3, 18 or 21.

artículo científico publicado en 1998

Physicochemical Properties Govern the Activity of Potent Antiviral Flavones ⬇️

artículo científico publicado en 2019

Potent and specific inhibitors of trypanothione reductase from Trypanosoma cruzi: bis(2-aminodiphenylsulfides) for fluorescent labeling studies

artículo científico publicado en 2001

QSAR modeling and chemical space analysis of antimalarial compounds

artículo científico publicado en 2017

Redox Polypharmacology as an Emerging Strategy to Combat Malarial Parasites

artículo científico publicado en 2016

Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections

artículo científico publicado en 2020

Screening of Plasmodium falciparum iron superoxide dismutase inhibitors and accuracy of the SOD-assays

artículo científico publicado en 2003

Selenium Status in Elderly People: Longevity and Age-Related Diseases

scientific article published on 01 January 2019

Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents.

artículo científico publicado en 2006

Structure-activity relationships in 2-aminodiphenylsulfides against trypanothione reductase from Trypanosoma cruzi

artículo científico publicado en 1998

Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents

artículo científico publicado en 2012

Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs

artículo científico publicado en 2015

Synthesis of 5,5'-dithiobis(2-nitrobenzamides) as alternative substrates for trypanothione reductase and thioredoxin reductase: a microtiter colorimetric assay for inhibitor screening

artículo científico publicado en 1999

Synthesis of 5-nitro-2-furancarbohydrazides and their cis-diamminedichloroplatinum complexes as bitopic and irreversible human thioredoxin reductase inhibitors

artículo científico publicado en 2005

Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation.

artículo científico publicado en 2018

Synthesis of polyamine derivatives for the preparation of affinity chromatography columns for the search of new Trypanosoma cruzi targets

artículo científico publicado en 1999

The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites

artículo científico publicado en 2016

The antimalarial activities of methylene blue and the 1,4-naphthoquinone 3-[4-(trifluoromethyl)benzyl]-menadione are not due to inhibition of the mitochondrial electron transport chain

artículo científico publicado en 2013

The aza-analogues of 1,4-naphthoquinones are potent substrates and inhibitors of plasmodial thioredoxin and glutathione reductases and of human erythrocyte glutathione reductase

artículo científico publicado en 2008

The conserved redox-sensitive cysteine residue of the DNA-binding region in the c-Rel protein is involved in the regulation of the phosphorylation of the protein

artículo científico publicado en 2000

The mineralocorticoid activity of progesterone derivatives depends on the nature of the C18 substituent

artículo científico publicado en 1995

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

artículo científico publicado en 2007

Trypanosoma cruzi prolyl oligopeptidase Tc80 is involved in nonphagocytic mammalian cell invasion by trypomastigotes.

artículo científico publicado en 2001

Trypanothione reductase inhibition/trypanocidal activity relationships in a 1,4-bis(3-aminopropyl)piperazine series

artículo científico publicado en 2000

Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases

artículo científico publicado en 2006

Unsaturated Mannich bases active against multidrug-resistant Trypanosoma brucei brucei strains

artículo científico publicado en 2009

Lista de obras de Elisabeth Davioud-Charvet

1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agents

18-Vinyldeoxycorticosterone: a potent inhibitor of the bovine cytochrome P -450 11β

2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity.

5-substituted tetrazoles as bioisosteres of carboxylic acids. Bioisosterism and mechanistic studies on glutathione reductase inhibitors as antimalarials

A General Approach to the Synthesis of Polyamine Linked-Monoindolylmaleimides, a New Series of Trypanothione Reductase Inhibitors

A Mild and Versatile Friedel-Crafts Methodology for the Diversity-Oriented Synthesis of Redox-Active 3-Benzoylmenadiones with Tunable Redox Potentials

A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs

A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme

A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assay

A novel mechanism for inhibition of HIV-1 reverse transcriptase

A physico-biochemical study on potential redox-cyclers as antimalarial and anti-schistosomal drugs.

A plant-derived flavonoid inhibits entry of all HCV genotypes into human hepatocytes

A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline.

A sugar-modified phosphole gold complex with antiproliferative properties acting as a thioredoxin reductase inhibitor in MCF-7 cells

An improved synthesis of 18-norandrost-4-ene-3,17-dione

AntiMalarial Mode of Action (AMMA) Database: Data Selection, Verification and Chemical Space Analysis

Antiglioma activity of GoPI-sugar, a novel gold(I)-phosphole inhibitor: chemical synthesis, mechanistic studies, and effectiveness in vivo.

Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats

Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker

Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum

Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA.

Antimalarial, antitrypanosomal, and antileishmanial activities and cytotoxicity of bis(9-amino-6-chloro-2-methoxyacridines): influence of the linker

Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase

Antiplasmodial activity and cytotoxicity of bis-, tris-, and tetraquinolines with linear or cyclic amino linkers

Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides.

Arylmethylamino steroids as antiparasitic agents

Author Correction: Arylmethylamino steroids as antiparasitic agents

Bromination studies of the 2,3-dimethylnaphthazarin core allowing easy access to naphthazarin derivatives

Comparison of the inhibition of human and Trypanosoma cruzi prolyl endopeptidases

Correction: Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target

Double-drug development against antioxidant enzymes from Plasmodium falciparum

Electrochemical properties of substituted 2-methyl-1,4-naphthoquinones: redox behavior predictions

Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials

Evidence for the co-existence of glutathione reductase and trypanothione reductase in the non-trypanosomatid Euglenozoa: Euglena gracilis Z

Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase

Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites

Glutathione-dependent activities of Trypanosoma cruzi p52 makes it a new member of the thiol:disulphide oxidoreductase family

High Sensitivity to Auxin is a Common Feature of Hairy Root

In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids.

Interactions of the antimalarial drug methylene blue with methemoglobin and heme targets in Plasmodium falciparum: a physico-biochemical study

Investigating the mode of action of the redox-active antimalarial drug plasmodione using the yeast model

Iridoids of Guyanese Species of Stigmaphyllon

Iron(iii) coordination properties of ladanein, a flavone lead with a broad-spectrum antiviral activity

Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate

Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity

Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase

New spermine and spermidine derivatives as potent inhibitors of Trypanosoma cruzi Trypanothione Reductase

New steroidal diazo ketones as potential photoaffinity labeling reagents for the mineralocorticoid receptor: synthesis and biological activities.

Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties

Photoaffinity labelling of the human mineralocorticoid receptor with steroids having a reactive group at position 3, 18 or 21.

Physicochemical Properties Govern the Activity of Potent Antiviral Flavones ⬇️

Potent and specific inhibitors of trypanothione reductase from Trypanosoma cruzi: bis(2-aminodiphenylsulfides) for fluorescent labeling studies

QSAR modeling and chemical space analysis of antimalarial compounds

Redox Polypharmacology as an Emerging Strategy to Combat Malarial Parasites

Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections

Screening of Plasmodium falciparum iron superoxide dismutase inhibitors and accuracy of the SOD-assays

Selenium Status in Elderly People: Longevity and Age-Related Diseases

Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents.

Structure-activity relationships in 2-aminodiphenylsulfides against trypanothione reductase from Trypanosoma cruzi

Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents

Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs

Synthesis of 5,5'-dithiobis(2-nitrobenzamides) as alternative substrates for trypanothione reductase and thioredoxin reductase: a microtiter colorimetric assay for inhibitor screening

Synthesis of 5-nitro-2-furancarbohydrazides and their cis-diamminedichloroplatinum complexes as bitopic and irreversible human thioredoxin reductase inhibitors

Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation.

Synthesis of polyamine derivatives for the preparation of affinity chromatography columns for the search of new Trypanosoma cruzi targets

The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites

The antimalarial activities of methylene blue and the 1,4-naphthoquinone 3-[4-(trifluoromethyl)benzyl]-menadione are not due to inhibition of the mitochondrial electron transport chain

The aza-analogues of 1,4-naphthoquinones are potent substrates and inhibitors of plasmodial thioredoxin and glutathione reductases and of human erythrocyte glutathione reductase

The conserved redox-sensitive cysteine residue of the DNA-binding region in the c-Rel protein is involved in the regulation of the phosphorylation of the protein

The mineralocorticoid activity of progesterone derivatives depends on the nature of the C18 substituent

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

Trypanosoma cruzi prolyl oligopeptidase Tc80 is involved in nonphagocytic mammalian cell invasion by trypomastigotes.

Trypanothione reductase inhibition/trypanocidal activity relationships in a 1,4-bis(3-aminopropyl)piperazine series

Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases

Unsaturated Mannich bases active against multidrug-resistant Trypanosoma brucei brucei strains