Filtros de búsqueda

Lista de obras de Clemens Decristoforo

(68)Ga-PSMA PET/CT for restaging recurrent prostate cancer: which factors are associated with PET/CT detection rate?

artículo científico publicado en 2015

(68)Ga-PSMA PET/CT imaging of metastatic clear cell renal cell carcinoma.

artículo científico publicado en 2014

(68)Ga-PSMA ligand PET versus (18)F-NaF PET: evaluation of response to (223)Ra therapy in a prostate cancer patient.

artículo científico publicado en 2014

68Ga- and 111In-labelled DOTA-RGD peptides for imaging of alphavbeta3 integrin expression

artículo científico publicado en 2008

68Ga-DOTA-TOC uptake in neuroendocrine tumour and healthy tissue: differentiation of physiological uptake and pathological processes in PET/CT.

artículo científico publicado en 2013

68Ga-DOTA-Tyr3-Octreotide PET in Neuroendocrine Tumors: Comparison with Somatostatin Receptor Scintigraphy and CT

artículo científico publicado en 2007

68Ga-DOTA-Tyr3-octreotide PET for assessing response to somatostatin-receptor-mediated radionuclide therapy

artículo científico publicado en 2009

68Ga-PSMA-11 PET/CT in primary staging of prostate cancer: PSA and Gleason score predict the intensity of tracer accumulation in the primary tumour

artículo científico publicado en 2017

99m-Technetium-labelled peptide-HYNIC conjugates: effects of lipophilicity and stability on biodistribution

artículo científico publicado en 1999

99mTc-EDDA/HYNIC-TOC and (18)F-FDG in thyroid cancer patients with negative (131)I whole-body scans.

artículo científico publicado en 2003

99mTc-EDDA/HYNIC-TOC scintigraphy in oncological diagnostics: methodological considerations

artículo científico publicado en 2004

99mTc-EDDA/HYNIC-TOC: a new 99mTc-labelled radiopharmaceutical for imaging somatostatin receptor-positive tumours: first clinical results and intra-patient comparison with 111In-labelled octreotide derivatives

scientific article published on 01 September 2000

99mTc-EDDA/HYNIC-Tyr(3)-octreotide for staging and follow-up of patients with neuroendocrine gastro-entero-pancreatic tumors.

artículo científico publicado en 2005

99mTc-HYNIC-[Tyr3]-octreotide for imaging somatostatin-receptor-positive tumors: preclinical evaluation and comparison with 111In-octreotide

artículo científico publicado en 2000

99mTc-N4-[Tyr3]Octreotate Versus 99mTc-EDDA/HYNIC-[Tyr3]Octreotide: an intrapatient comparison of two novel Technetium-99m labeled tracers for somatostatin receptor scintigraphy.

artículo científico publicado en 2004

99mTc-labeling and in vitro and in vivo evaluation of HYNIC- and (Nalpha-His)acetic acid-modified [D-Glu1]-minigastrin.

artículo científico publicado en 2004

99mTc-labelled HYNIC-minigastrin with reduced kidney uptake for targeting of CCK-2 receptor-positive tumours

scientific article published on 17 February 2007

A fully automated synthesis for the preparation of 68Ga-labelled peptides.

artículo científico publicado en 2007

A novel CCK2/gastrin receptor-localizing radiolabeled peptide probe for personalized diagnosis and therapy of patients with progressive or metastatic medullary thyroid carcinoma: a multicenter phase I GRAN-T-MTC study

scientific article published on 05 December 2018

A retrospective comparison between 68Ga-DOTA-TOC PET/CT and 18F-DOPA PET/CT in patients with extra-adrenal paraganglioma.

artículo científico publicado en 2013

A simple two-strip method to determine the radiochemical purity of technetium-99m mercaptoacetyltriglycine

artículo científico publicado en 1993

An intrapatient comparison of 99mTc-EDDA/HYNIC-TOC with 111In-DTPA-octreotide for diagnosis of somatostatin receptor-expressing tumors

artículo científico publicado en 2003

An iron-mimicking, Trojan horse-entering fungi--has the time come for molecular imaging of fungal infections?

artículo científico publicado en 2015

Analysis of accumulation of 99mTc-octreotide and 99mTc-EDDA/HYNIC-Tyr3-octreotide in the rat kidneys.

artículo científico publicado en 2004

Are we "preparing" radiopharmaceuticals?

artículo científico publicado en 2016

Bone metastases in patients with neuroendocrine tumor: 68Ga-DOTA-Tyr3-octreotide PET in comparison to CT and bone scintigraphy.

artículo científico publicado en 2009

Brain perfusion scintigraphy with 99mTc-HMPAO or 99mTc-ECD and 123I-beta-CIT single-photon emission tomography in dementia of the Alzheimer-type and diffuse Lewy body disease

artículo científico publicado en 1997

Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m

article

Clinical translation of theranostic radiopharmaceuticals: Current regulatory status and recent examples

artículo científico publicado en 2019

Comparison of 68Ga-DOTATATE and 68Ga-DOTANOC PET/CT imaging in the same patient group with neuroendocrine tumours

artículo científico publicado en 2012

Comparison of 68Ga-labeled RGD mono- and multimers based on a clickable siderophore-based scaffold

scientific article published on 25 October 2019

Comparison of Ga-68-Labeled Fusarinine C-Based Multivalent RGD Conjugates and [(68)Ga]NODAGA-RGD-In Vivo Imaging Studies in Human Xenograft Tumors

scientific article published on 23 February 2016

Comparison of PEGylated and non-PEGylated proticles: An in vitro and in vivo study

scientific article published on 02 September 2019

Comparison of [68Ga]Ga-PSMA-11 PET/CT with [18F]NaF PET/CT in the evaluation of bone metastases in metastatic prostate cancer patients prior to radionuclide therapy

scientific article published on 16 May 2018

Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607.

artículo científico publicado en 2011

Comparison of different methods for radiochemical purity testing of [99mTc-EDDA-HYNIC-D-Phe1,Tyr3]-octreotide.

artículo científico publicado en 2005

Comparison of in vitro and in vivo properties of [99mTc]cRGD peptides labeled using different novel Tc-cores.

artículo científico publicado en 2007

Correction: Klingler, M., et al. Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m. Pharmaceuticals 2019, 12, 13

artículo científico publicado en 2019

Current status of theranostics in prostate cancer.

artículo científico publicado en 2017

Cyclic minigastrin analogues for gastrin receptor scintigraphy with technetium-99m: preclinical evaluation.

artículo científico publicado en 2009

Cyclic versus Noncyclic Chelating Scaffold for 89Zr-Labeled ZEGFR:2377 Affibody Bioconjugates Targeting Epidermal Growth Factor Receptor Overexpression

artículo científico publicado en 2017

DOTA-MGS5, a New Cholecystokinin-2 Receptor-Targeting Peptide Analog with an Optimized Targeting Profile for Theranostic Use

scientific article published on 07 December 2018

Design and evaluation of novel radiolabelled VIP derivatives for tumour targeting.

artículo científico publicado en 2013

Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y₁)- and GRP-Receptors-An Improvement for Breast Cancer Imaging?

scholarly article by Alicia Vall-Sagarra et al published 4 July 2018 in Pharmaceuticals

Detection of somatostatin receptor-positive tumours using the new 99mTc-tricine-HYNIC-d-Phel-Tyr3-octreotide: first results in patients and comparison with 111In-DTPA-D-Phe1-octreotide

artículo científico publicado en 2000

Determination of Sn(II) in technetium cold kits by voltammetry at the hanging mercury drop electrode (HMDE) and relevant radiopharmaceutical applications

artículo científico publicado en 1998

Developing Targeted Hybrid Imaging Probes by Chelator Scaffolding

artículo científico publicado en 2017

EANM guideline for the preparation of an Investigational Medicinal Product Dossier (IMPD)

artículo científico publicado en 2014

EANM guideline on the validation of analytical methods for radiopharmaceuticals

artículo científico publicado en 2020

Early PET imaging with [68]Ga-PSMA-11 increases the detection rate of local recurrence in prostate cancer patients with biochemical recurrence.

artículo científico publicado en 2017

Early dynamic imaging in 68Ga- PSMA-11 PET/CT allows discrimination of urinary bladder activity and prostate cancer lesions

artículo científico publicado en 2016

Erratum to: Guideline for PET/CT imaging of neuroendocrine neoplasms with (68)Ga-DOTA-conjugated somatostatin receptor targeting peptides and (18)F-DOPA.

artículo científico publicado en 2017

Erratum: Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting: Erratum

artículo científico publicado en 2019

Erythroid 5-aminolevulinate synthase, ferrochelatase and DMT1 expression in erythroid progenitors: differential pathways for erythropoietin and iron-dependent regulation

artículo científico publicado en 2002

European regulations for the introduction of novel radiopharmaceuticals in the clinical setting.

artículo científico publicado en 2017

Evaluation of [123I]IBZM pinhole SPECT for the detection of striatal dopamine D2 receptor availability in rats.

artículo científico publicado en 2004

Evaluation of striatal dopamine transporter function in rats by in vivo beta-[123I]CIT pinhole SPECT.

artículo científico publicado en 2002

Evidence for Somatostatin receptor 2 in thyroid tissue.

artículo científico publicado en 2006

Exploiting the Concept of Multivalency with 68Ga- and 89Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression.

artículo científico publicado en 2018

Expression of somatostatin receptor subtype 2 and subtype 5 in thyroid malignancies

scientific article published on 26 June 2014

Failure of labelling of anti-granulocyte antibody

scientific article published on 01 June 1993

Feasibility and availability of ⁶⁸Ga-labelled peptides.

artículo científico publicado en 2012

From preclinical development to clinical application: Kit formulation for radiolabelling the minigastrin analogue CP04 with In-111 for a first-in-human clinical trial

artículo científico publicado en 2016

Full automation of (68)Ga labelling of DOTA-peptides including cation exchange prepurification.

artículo científico publicado en 2009

Functional imaging in phaeochromocytoma and neuroblastoma with 68Ga-DOTA-Tyr 3-octreotide positron emission tomography and 123I-metaiodobenzylguanidine

artículo científico publicado en 2011

Functional imaging in phaeochromocytoma and neuroblastoma with 68Ga-DOTA-Tyr3-octreotide positron emission tomography and 123I-metaiodobenzylguanidine: a clarification.

artículo científico publicado en 2012

Fusarinine C, a novel siderophore-based bifunctional chelator for radiolabeling with Gallium-68.

artículo científico publicado en 2015

Gallium-68 -- a new opportunity for PET available from a long shelf-life generator - automation and applications

artículo científico publicado en 2012

Guidance on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals

artículo científico publicado en 2010

Guidance on current good radiopharmacy practice for the small-scale preparation of radiopharmaceuticals using automated modules: a European perspective

artículo científico publicado en 2014

Guideline for PET/CT imaging of neuroendocrine neoplasms with 68Ga-DOTA-conjugated somatostatin receptor targeting peptides and 18F-DOPA.

artículo científico publicado en 2017

Harmonization of United States, European Union and Canadian First-in-Human Regulatory Requirements for Radiopharmaceuticals-Is This Possible?

scientific article published on 27 September 2018

Highlights lecture EANM 2015: the search for nuclear medicine's superheroes

artículo científico publicado en 2016

Highlights of the 30th Annual Congress of the EANM, Vienna 2017: "Yes we can - make nuclear medicine great again"

article

Hybrid Imaging Agents for Pretargeting Applications Based on Fusarinine C-Proof of Concept

artículo científico publicado en 2020

Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores

scientific article published on 22 January 2020

Image fusion analysis of (99m)Tc-HYNIC-Tyr(3)-octreotide SPECT and diagnostic CT using an immobilisation device with external markers in patients with endocrine tumours.

artículo científico publicado en 2005

Image fusion analysis of 99m Tc-HYNIC-octreotide scintigraphy and CT/MRI in patients with thyroid-associated orbitopathy: the importance of the lacrimal gland.

artículo científico publicado en 2003

Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography

artículo científico publicado en 2018

Improved quality control of [177Lu]Lu-PSMA I&T

Impurity in (68)Ga-peptide preparation using processed generator eluate.

artículo científico publicado en 2010

In Vitro and In Vivo Comparison of Selected Ga-68 and Zr-89 Labelled Siderophores.

artículo científico publicado en 2015

In Vivo Characterization of 4 Ga-Labeled Multimeric RGD Peptides to Image αβ Integrin Expression in 2 Human Tumor Xenograft Mouse Models

In vitro and in vivo evaluation of a novel 99mTc(CO)3-pyrazolyl conjugate of cyclo-(Arg-Gly-Asp-d-Tyr-Lys).

artículo científico publicado en 2007

In vitro and in vivo evaluation of selected 68Ga-siderophores for infection imaging

artículo científico publicado en 2011

Influence of PEGylation and RGD loading on the targeting properties of radiolabeled liposomal nanoparticles

artículo científico publicado en 2012

Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue

artículo científico publicado en 2015

Influence of biological assay conditions on stability assessment of radiometal-labelled peptides exemplified using a 177Lu-DOTA-minigastrin derivative.

artículo científico publicado en 2011

Methodological considerations influence the clinical value of parathyroid localisation diagnostics

artículo científico publicado en 2001

Microbial challenge tests on nonradioactive TiO2-based 68Ge/68Ga generator columns

artículo científico publicado en 2012

Modifying the Siderophore Triacetylfusarinine C for Molecular Imaging of Fungal Infection

artículo científico publicado en 2019

Molecular Design of <sup>68</sup>Ga- and <sup>89</sup>Zr-Labeled Anticalin Radioligands for PET-Imaging of PSMA-Positive Tumors

Molecular Imaging: In Vivo Agents for the Diagnosis and Treatment of Cancer

scientific article published on 22 October 2018

Multimerization results in formation of re-bindable metabolites: A proof of concept study with FSC-based minigastrin imaging probes targeting CCK2R expression

artículo científico publicado en 2018

Myocardial fatty acid metabolism during acute cardiac allograft rejection

artículo científico publicado en 1998

Novel 99mTc '4 + 1' peptide conjugates: tuning the biodistribution by variation of coligands.

artículo científico publicado en 2010

Novel Bifunctional Cyclic Chelator for (89)Zr Labeling-Radiolabeling and Targeting Properties of RGD Conjugates

artículo científico publicado en 2015

On-cartridge preparation and evaluation of 68Ga-, 89Zr- and 64Cu-precursors for cell radiolabelling

artículo científico publicado en 2019

Peptide targeted imaging of cancer.

artículo científico publicado en 2003

Position paper on requirements for toxicological studies in the specific case of radiopharmaceuticals

article

Preclinical evaluation of radiolabeled DOTA-derivatized cyclic minigastrin analogs for targeting cholecystokinin receptor expressing malignancies.

artículo científico publicado en 2012

Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging.

artículo científico publicado en 2012

Preclinical pharmacokinetics, biodistribution, radiation dosimetry and toxicity studies required for regulatory approval of a phase I clinical trial with (111)In-CP04 in medullary thyroid carcinoma patients

artículo científico publicado en 2016

Preparation, 99mTc-labeling, and in vitro characterization of HYNIC and N3S modified RC-160 and [Tyr3]octreotide

artículo científico publicado en 1999

Preparation,99mTc-Labeling, and in Vitro Characterization of Hynic and N3S Modified RC-160 and [TYR3]octreotide

scientific article published on 01 July 1999

Pretargeted Imaging with Gallium-68-Improving the Binding Capability by Increasing the Number of Tetrazine Motifs

article

Problems with fractionated cold kits

artículo científico publicado en 1996

Radiochemical purity of routinely prepared 99Tcm radiopharmaceuticals: A retrospective study

scientific article published on 01 April 2000

Radiolabeling of lipid-based nanoparticles for diagnostics and therapeutic applications: a comparison using different radiometals

artículo científico publicado en 2010

Radiolabelling of peptides for PET, SPECT and therapeutic applications using a fully automated disposable cassette system

artículo científico publicado en 2011

Radionuclides: medicinal products or rather starting materials?

scientific article published on 20 August 2019

Radiopharmaceutical development of a freeze-dried kit formulation for the preparation of [99mTc-EDDA-HYNIC-D-Phe1, Tyr3]-octreotide, a somatostatin analog for tumor diagnosis

artículo científico publicado en 2004

Radiopharmaceuticals are special, but is this recognized? The possible impact of the new Clinical Trials Regulation on the preparation of radiopharmaceuticals.

artículo científico publicado en 2014

Radiopharmacy: regulations and legislations in relation to human applications

artículo científico publicado en 2011

Rational Design, Synthesis and Preliminary Evaluation of Novel Fusarinine C-Based Chelators for Radiolabeling with Zirconium-89

article

Role of radiopharmaceuticals in the diagnosis and treatment of neuroendocrine tumours

artículo científico publicado en 2009

Selected ⁶⁸Ga-siderophores versus ⁶⁸Ga-colloid and ⁶⁸Ga-citrate: biodistribution and small animal imaging in mice

artículo científico publicado en 2014

Selection of the First <sup>99m</sup>Tc-Labelled Somatostatin Receptor Subtype 2 Antagonist for Clinical Translation-Preclinical Assessment of Two Optimized Candidates

artículo científico publicado en 2020

Siderophore Scaffold as Carrier for Antifungal Peptides in Therapy of <i>Aspergillus fumigatus</i> Infections

scientific article published on 15 December 2020

Siderophore-Based Molecular Imaging of Fungal and Bacterial Infections-Current Status and Future Perspectives

artículo científico publicado en 2020

Siderophores for molecular imaging applications.

scientific article published on 11 October 2016

Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting.

artículo científico publicado en 2018

Small animal imaging using a conventional gamma camera exemplified in studies on the striatal dopaminergic system.

artículo científico publicado en 2006

Somatostatin receptor scintigraphy using (99m)Tc-EDDA/HYNIC-TOC in graves' disease

artículo científico publicado en 2002

Surfactant protein B labelled with [99mTc(CO)3(H2O)3]+ retains biological activity in vitro

artículo científico publicado en 2001

Synthesis, in vitro and in vivo evaluation of 18F-fluoronorimatinib as radiotracer for Imatinib-sensitive gastrointestinal stromal tumors

artículo científico publicado en 2017

Targeting Gastrointestinal Stromal Tumor with 68Ga-Labeled Peptides: An In Vitro Study on Gastrointestinal Stromal Tumor-Cell Lines.

artículo científico publicado en 2016

Targeting properties of peptide-modified radiolabeled liposomal nanoparticles

artículo científico publicado en 2011

Technetium-99m human immunoglobulin scintigraphy in psoriatic arthropathy: first results

artículo científico publicado en 1994

Technetium-99m somatostatin analogues: effect of labelling methods and peptide sequence

artículo científico publicado en 1999

The 68Ga/177Lu theragnostic concept in PSMA targeting of castration-resistant prostate cancer: correlation of SUVmax values and absorbed dose estimates.

artículo científico publicado en 2017

The Siderophore Transporter Sit1 Determines Susceptibility to the Antifungal VL-2397

scientific article published on 23 September 2019

The influence of chelator on the pharmacokinetics of 99mTc-labelled peptides.

artículo científico publicado en 2002

The new Regulation on clinical trials in relation to radiopharmaceuticals: when and how will it be implemented?

artículo científico publicado en 2019

The specific case of radiopharmaceuticals and GMP—activities of the Radiopharmacy Committee

artículo científico publicado en 2008

The use of electronic autoradiography in radiopharmacy

artículo científico publicado en 1997

Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles

artículo científico publicado en 2013

US and EU radiopharmaceutical diagnostic and therapeutic nonclinical study requirements for clinical trials authorizations and marketing authorizations

artículo científico publicado en 2019

Ultra-low activities of a common radioisotope for permission-free tracking of a drosophilid fly in its natural habitat

artículo científico publicado en 2016

Untangling the web of European regulations for the preparation of unlicensed radiopharmaceuticals: a concise overview and practical guidance for a risk-based approach.

artículo científico publicado en 2015

[(68)Ga]FSC-(RGD)3 a trimeric RGD peptide for imaging αvβ3 integrin expression based on a novel siderophore derived chelating scaffold-synthesis and evaluation

artículo científico publicado en 2014

[(68)Ga]NODAGA-RGD - Metabolic stability, biodistribution, and dosimetry data from patients with hepatocellular carcinoma and liver cirrhosis

artículo científico publicado en 2016

[68Ga]NODAGA-RGD for imaging αvβ3 integrin expression.

artículo científico publicado en 2011

[99mTc]HYNIC-RGD for imaging integrin alphavbeta3 expression

artículo científico publicado en 2006

[99mTc]demotensin VI: biodistribution and initial clinical results in tumor patients of a pilot/phase I study

artículo científico publicado en 2011

[Quality control of radiopharmaceuticals from the clinical aspect--a necessity?]

artículo científico publicado en 1993

[⁶⁸Ga]NS₃-RGD and [⁶⁸Ga] Oxo-DO3A-RGD for imaging α(v)β₃ integrin expression: synthesis, evaluation, and comparison.

artículo científico publicado en 2012

⁶⁸Ga-DOTA⁰-Tyr³-octreotide positron emission tomography in head and neck squamous cell carcinoma.

artículo científico publicado en 2013