Lista de obras - Rainer Lehtonen - Dominio Público Uruguay

A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients

artículo científico publicado en 2018

A novel functionally deficient MYH variant in individuals with colorectal adenomatous polyposis.

artículo científico publicado en 2005

Alternative splicing discriminates molecular subtypes and has prognostic impact in diffuse large B-cell lymphoma.

artículo científico publicado en 2017

Anagrelide for Gastrointestinal Stromal Tumor

scientific article published on 07 December 2018

Analysis of KLHDC8B in familial nodular lymphocyte predominant Hodgkin lymphoma.

artículo científico publicado en 2011

Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer

article

Analysis of fumarate hydratase mutations in a population-based series of early onset uterine leiomyosarcoma patients

artículo científico publicado en 2006

BMPR2mutation in a patient with pulmonary arterial hypertension and suspected hereditary hemorrhagic telangiectasia

artículo científico publicado en 2008

Background Mutation Frequency in Microsatellite-Unstable Colorectal Cancer

artículo científico publicado en 2007

Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance

artículo científico publicado en 2021

Complete androgen insensitivity syndrome caused by a deep intronic pseudoexon-activating mutation in the androgen receptor gene

artículo científico publicado en 2016

Computational identification of cancer susceptibility loci.

artículo científico publicado en 2010

Computational identification of candidate loci for recessively inherited mutation using high-throughput SNP arrays

artículo científico publicado en 2007

Cytochrome P450 gene CYP337 and heritability of fitness traits in the Glanville fritillary butterfly

artículo científico publicado en 2014

Data integration to prioritize drugs using genomics and curated data.

artículo científico publicado en 2016

Definition of a minimal region of deletion of chromosome 7 in uterine leiomyomas by tiling-path microarray CGH and mutation analysis of known genes in this region

article

Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma

artículo científico publicado en 2017

Distinct subtypes of diffuse large B-cell lymphoma defined by hypermutated genes

artículo científico publicado en 2019

EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis

artículo científico publicado en 2006

Effects of ambient and preceding temperatures and metabolic genes on flight metabolism in the Glanville fritillary butterfly

artículo científico publicado en 2015

Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma

artículo científico publicado en 2011

Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.

artículo científico publicado en 2016

Fine mapping of 11q13.5 identifies regions associated with prostate cancer and prostate cancer death

artículo científico publicado en 2013

Flight-induced changes in gene expression in the Glanville fritillary butterfly.

artículo científico publicado en 2015

Genetic effects on life-history traits in the Glanville fritillary butterfly

artículo científico publicado en 2017

Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

article

Genomic profile of pseudomyxoma peritonei analyzed using next-generation sequencing and immunohistochemistry

Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma

artículo científico publicado en 2006

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

artículo científico publicado en 2002

High genetic load in an old isolated butterfly population.

artículo científico publicado en 2012

Identification of Prognostic Groups in High-Grade Serous Ovarian Cancer Treated with Platinum-Taxane Chemotherapy.

artículo científico publicado en 2015

Identification of sample-specific regulations using integrative network level analysis

artículo científico publicado en 2015

Identifying differentially methylated sites in samples with varying tumor purity

scientific article published on 01 September 2018

Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans

artículo científico publicado en 2019

Lep-MAP: fast and accurate linkage map construction for large SNP datasets

artículo científico publicado en 2013

Little evidence for involvement of MLH3 in colorectal cancer predisposition

artículo científico publicado en 2003

Mathematical Modeling Predicts Response to Chemotherapy and Drug Combinations in Ovarian Cancer

scientific article published on 16 May 2018

MicroRNAs regulate key cell survival pathways and mediate chemosensitivity during progression of diffuse large B-cell lymphoma.

artículo científico publicado en 2017

Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei

artículo científico publicado en 2017

Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome

artículo científico publicado en 2005

Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer

article

Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers

artículo científico publicado en 2005

Nationwide registry-based analysis of cancer clustering detects strong familial occurrence of Kaposi sarcoma

artículo científico publicado en 2013

No evidence for a genetic modifier for renal cell cancer risk in HLRCC syndrome.

artículo científico publicado en 2010

No germline FH mutations in familial breast cancer patients

PerPAS: Topology-Based Single Sample Pathway Analysis Method.

artículo científico publicado en 2017

Phenotypic plasticity in thermal tolerance in the Glanville fritillary butterfly.

artículo científico publicado en 2014

Pituitary adenoma predisposition caused by germline mutations in the AIP gene

artículo científico publicado en 2006

Plastic larval development in a butterfly has complex environmental and genetic causes and consequences for population dynamics

artículo científico publicado en 2013

Predictable allele frequency changes due to habitat fragmentation in the Glanville fritillary butterfly.

artículo científico publicado en 2016

Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps

artículo científico publicado en 2013

Prospective Longitudinal ctDNA Workflow Reveals Clinically Actionable Alterations in Ovarian Cancer

artículo científico publicado en 2019

Recessively inherited right atrial isomerism caused by mutations in growth/differentiation factor 1 (GDF1)

article published in 2010

Rule-based induction method for haplotype comparison and identification of candidate disease loci

artículo científico publicado en 2012

SNP design from 454 sequencing of Podosphaera plantaginis transcriptome reveals a genetically diverse pathogen metapopulation with high levels of mixed-genotype infection

artículo científico publicado en 2012

SePIA: RNA and small RNA sequence processing, integration, and analysis.

artículo científico publicado en 2016

Temperature- and sex-related effects of serine protease alleles on larval development in the Glanville fritillary butterfly

artículo científico publicado en 2015

The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera

artículo científico publicado en 2014

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.

artículo científico publicado en 2009

Lista de obras de Rainer Lehtonen

A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients

A novel functionally deficient MYH variant in individuals with colorectal adenomatous polyposis.

Alternative splicing discriminates molecular subtypes and has prognostic impact in diffuse large B-cell lymphoma.

Anagrelide for Gastrointestinal Stromal Tumor

Analysis of KLHDC8B in familial nodular lymphocyte predominant Hodgkin lymphoma.

Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer

Analysis of fumarate hydratase mutations in a population-based series of early onset uterine leiomyosarcoma patients

BMPR2mutation in a patient with pulmonary arterial hypertension and suspected hereditary hemorrhagic telangiectasia

Background Mutation Frequency in Microsatellite-Unstable Colorectal Cancer

Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance

Complete androgen insensitivity syndrome caused by a deep intronic pseudoexon-activating mutation in the androgen receptor gene

Computational identification of cancer susceptibility loci.

Computational identification of candidate loci for recessively inherited mutation using high-throughput SNP arrays

Cytochrome P450 gene CYP337 and heritability of fitness traits in the Glanville fritillary butterfly

Data integration to prioritize drugs using genomics and curated data.

Definition of a minimal region of deletion of chromosome 7 in uterine leiomyomas by tiling-path microarray CGH and mutation analysis of known genes in this region

Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma

Distinct subtypes of diffuse large B-cell lymphoma defined by hypermutated genes

EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis

Effects of ambient and preceding temperatures and metabolic genes on flight metabolism in the Glanville fritillary butterfly

Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma

Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.

Fine mapping of 11q13.5 identifies regions associated with prostate cancer and prostate cancer death

Flight-induced changes in gene expression in the Glanville fritillary butterfly.

Genetic effects on life-history traits in the Glanville fritillary butterfly

Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

Genomic profile of pseudomyxoma peritonei analyzed using next-generation sequencing and immunohistochemistry

Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

High genetic load in an old isolated butterfly population.

Identification of Prognostic Groups in High-Grade Serous Ovarian Cancer Treated with Platinum-Taxane Chemotherapy.

Identification of sample-specific regulations using integrative network level analysis

Identifying differentially methylated sites in samples with varying tumor purity

Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans

Lep-MAP: fast and accurate linkage map construction for large SNP datasets

Little evidence for involvement of MLH3 in colorectal cancer predisposition

Mathematical Modeling Predicts Response to Chemotherapy and Drug Combinations in Ovarian Cancer

MicroRNAs regulate key cell survival pathways and mediate chemosensitivity during progression of diffuse large B-cell lymphoma.

Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei

Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome

Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer

Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers

Nationwide registry-based analysis of cancer clustering detects strong familial occurrence of Kaposi sarcoma

No evidence for a genetic modifier for renal cell cancer risk in HLRCC syndrome.

No germline FH mutations in familial breast cancer patients

PerPAS: Topology-Based Single Sample Pathway Analysis Method.

Phenotypic plasticity in thermal tolerance in the Glanville fritillary butterfly.

Pituitary adenoma predisposition caused by germline mutations in the AIP gene

Plastic larval development in a butterfly has complex environmental and genetic causes and consequences for population dynamics

Predictable allele frequency changes due to habitat fragmentation in the Glanville fritillary butterfly.

Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps

Prospective Longitudinal ctDNA Workflow Reveals Clinically Actionable Alterations in Ovarian Cancer

Recessively inherited right atrial isomerism caused by mutations in growth/differentiation factor 1 (GDF1)

Rule-based induction method for haplotype comparison and identification of candidate disease loci

SNP design from 454 sequencing of Podosphaera plantaginis transcriptome reveals a genetically diverse pathogen metapopulation with high levels of mixed-genotype infection

SePIA: RNA and small RNA sequence processing, integration, and analysis.

Temperature- and sex-related effects of serine protease alleles on larval development in the Glanville fritillary butterfly

The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.