Lista de obras - Jan Terje Andersen - Dominio Público Uruguay

A human endothelial cell-based recycling assay for screening of FcRn targeted molecules

artículo científico publicado en 2018

A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes

scientific article published on 02 December 2019

A receptor-mediated mechanism to support clinical observation of altered albumin variants

artículo científico publicado en 2007

A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance

artículo científico publicado en 2012

A strategy for bacterial production of a soluble functional human neonatal Fc receptor

artículo científico publicado en 2007

An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics

artículo científico publicado en 2020

An intact C-terminal end of albumin is required for its long half-life in humans

artículo científico publicado en 2020

Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life

artículo científico publicado en 2012

Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection

scientific article published on 29 August 2019

Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life

artículo científico publicado en 2022

Antibody-antigen kinetics constrain intracellular humoral immunity

artículo científico publicado en 2016

Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies

scientific article published on 14 January 2019

Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses

artículo científico publicado en 2019

Characterization of an FcgammaRI-binding peptide selected by phage display

artículo científico publicado en 2006

Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation

artículo científico publicado en 2013

Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

artículo científico publicado en 2011

Complement C4 Prevents Viral Infection through Capsid Inactivation

scientific article published on 26 March 2019

Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity

artículo científico publicado en 2017

Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding

artículo científico publicado en 2009

Dependence of antibody-mediated presentation of antigen on FcRn

artículo científico publicado en 2008

Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applications

artículo científico publicado en 2015

Dissecting the interaction between transglutaminase 2 and fibronectin

artículo científico publicado en 2016

Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies

artículo científico publicado en 2014

Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn

artículo científico publicado en 2014

Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high FcγRIIa affinity and selectivity

artículo científico publicado en 2012

Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin

artículo científico publicado en 2020

Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization

artículo científico publicado en 2015

Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain

artículo científico publicado en 2010

Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding

artículo científico publicado en 2014

Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions

artículo científico publicado en 2015

FcRn binding properties of an abnormal truncated analbuminemic albumin variant

artículo científico publicado en 2009

FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity

artículo científico publicado en 2020

Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury

artículo científico publicado en 2017

Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport

artículo científico publicado en 2018

Human and mouse albumin bind their respective neonatal Fc receptors differently

artículo científico publicado en 2018

Identification of a high affinity FcgammaRIIA-binding peptide that distinguishes FcgammaRIIA from FcgammaRIIB and exploits FcgammaRIIA-mediated phagocytosis and degradation

artículo científico publicado en 2008

Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn).

artículo científico publicado en 2014

Intracellular neutralisation of rotavirus by VP6-specific IgG

artículo científico publicado en 2020

Ligand binding and antigenic properties of a human neonatal Fc receptor with mutation of two unpaired cysteine residues

artículo científico publicado en 2008

Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions.

artículo científico publicado en 2013

NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies

artículo científico publicado en 2020

On the perplexingly low rate of transport of IgG2 across the human placenta

artículo científico publicado en 2014

Pharmaceutical compounding of aflibercept in prefilled syringes does not affect structural integrity, stability or VEGF and Fc binding properties.

artículo científico publicado en 2018

Polymeric human Fc-fusion proteins with modified effector functions

artículo científico publicado en 2011

Prolonged and increased expression of soluble Fc receptors, IgG and a TCR-Ig fusion protein by transiently transfected adherent 293E cells

artículo científico publicado en 2005

Publisher Correction: Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies

artículo científico publicado en 2019

Selection of nanobodies that target human neonatal Fc receptor.

artículo científico publicado en 2013

Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin fusion therapeutics

artículo científico publicado en 2013

Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease

artículo científico publicado en 2015

Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

artículo científico publicado en 2012

Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients

scientific article published on 17 September 2020

TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity

artículo científico publicado en 2016

TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination

article published in the Proceedings of the National Academy of Sciences of the United States of America

TRIM21-From Intracellular Immunity to Therapy

scientific article published on 28 August 2019

TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity

artículo científico publicado en 2015

Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate 177Lu-NNV003

scientific article published on 15 July 2019

The Neonatal Fc Receptor (FcRn): A Misnomer?

artículo científico publicado en 2019

The arabidopsis histone methyltransferase SUVR4 binds ubiquitin via a domain with a four-helix bundle structure

artículo científico publicado en 2014

The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin

artículo científico publicado en 2006

The neonatal Fc receptor in mucosal immune regulation

artículo científico publicado en 2020

The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery

artículo científico publicado en 2015

The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics.

scientific article published on January 2009

Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies

artículo científico publicado en 2015

Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics

artículo científico publicado en 2014

Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity

artículo científico publicado en 2020

Lista de obras de Jan Terje Andersen

A human endothelial cell-based recycling assay for screening of FcRn targeted molecules

A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes

A receptor-mediated mechanism to support clinical observation of altered albumin variants

A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance

A strategy for bacterial production of a soluble functional human neonatal Fc receptor

An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics

An intact C-terminal end of albumin is required for its long half-life in humans

Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life

Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection

Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life

Antibody-antigen kinetics constrain intracellular humoral immunity

Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies

Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses

Characterization of an FcgammaRI-binding peptide selected by phage display

Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation

Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

Complement C4 Prevents Viral Infection through Capsid Inactivation

Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity

Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding

Dependence of antibody-mediated presentation of antigen on FcRn

Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applications

Dissecting the interaction between transglutaminase 2 and fibronectin

Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies

Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn

Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high FcγRIIa affinity and selectivity

Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin

Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization

Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain

Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding

Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions

FcRn binding properties of an abnormal truncated analbuminemic albumin variant

FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity

Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury

Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport

Human and mouse albumin bind their respective neonatal Fc receptors differently

Identification of a high affinity FcgammaRIIA-binding peptide that distinguishes FcgammaRIIA from FcgammaRIIB and exploits FcgammaRIIA-mediated phagocytosis and degradation

Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn).

Intracellular neutralisation of rotavirus by VP6-specific IgG

Ligand binding and antigenic properties of a human neonatal Fc receptor with mutation of two unpaired cysteine residues

Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions.

NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies

On the perplexingly low rate of transport of IgG2 across the human placenta

Pharmaceutical compounding of aflibercept in prefilled syringes does not affect structural integrity, stability or VEGF and Fc binding properties.

Polymeric human Fc-fusion proteins with modified effector functions

Prolonged and increased expression of soluble Fc receptors, IgG and a TCR-Ig fusion protein by transiently transfected adherent 293E cells

Publisher Correction: Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies

Selection of nanobodies that target human neonatal Fc receptor.

Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin fusion therapeutics

Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease

Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients

TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity

TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination

TRIM21-From Intracellular Immunity to Therapy

TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity

Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate 177Lu-NNV003

The Neonatal Fc Receptor (FcRn): A Misnomer?

The arabidopsis histone methyltransferase SUVR4 binds ubiquitin via a domain with a four-helix bundle structure

The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin

The neonatal Fc receptor in mucosal immune regulation

The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery

The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics.

Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies

Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics

Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity