Lista de obras - Agustín Tortajada - Dominio Público Uruguay

3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase.

scholarly article

A novel antibody against human factor B that blocks formation of the C3bB proconvertase and inhibits complement activation in disease models.

artículo científico publicado en 2014

Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3.

artículo científico publicado en 2012

C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation

artículo científico publicado en 2013

Coexistence of closed and open conformations of complement factor B in the alternative pathway C3bB(Mg2+) proconvertase

artículo científico publicado en 2009

Complement factor H variants I890 and L1007 while commonly associated with atypical hemolytic uremic syndrome are polymorphisms with no functional significance

artículo científico publicado en 2011

FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation.

artículo científico publicado en 2017

Factor H-related proteins determine complement-activating surfaces

artículo científico

Familial C3 glomerulonephritis caused by a novel CFHR5-CFHR2 fusion gene

artículo científico publicado en 2016

Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications.

artículo científico publicado en 2017

Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B

scholarly article

Genetics of atypical hemolytic uremic syndrome (aHUS).

artículo científico publicado en 2014

Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration

artículo científico publicado en 2008

Molecular Basis of Factor H R1210C Association with Ocular and Renal Diseases.

artículo científico publicado en 2015

Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy

artículo científico publicado en 2015

Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin.

artículo científico publicado en 2013

The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity

artículo científico publicado en 2009

The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome.

artículo científico publicado en 2015

Variant-specific quantification of factor H in plasma identifies null alleles associated with atypical hemolytic uremic syndrome

artículo científico publicado en 2010

Lista de obras de Agustín Tortajada

3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase.

A novel antibody against human factor B that blocks formation of the C3bB proconvertase and inhibits complement activation in disease models.

Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3.

C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation

Coexistence of closed and open conformations of complement factor B in the alternative pathway C3bB(Mg2+) proconvertase

Complement factor H variants I890 and L1007 while commonly associated with atypical hemolytic uremic syndrome are polymorphisms with no functional significance

FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation.

Factor H-related proteins determine complement-activating surfaces

Familial C3 glomerulonephritis caused by a novel CFHR5-CFHR2 fusion gene

Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications.

Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B

Genetics of atypical hemolytic uremic syndrome (aHUS).

Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration

Molecular Basis of Factor H R1210C Association with Ocular and Renal Diseases.

Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy

Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin.

The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity

The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome.

Variant-specific quantification of factor H in plasma identifies null alleles associated with atypical hemolytic uremic syndrome