Lista de obras - Manlio Palumbo - Dominio Público Uruguay

2,6-Di(omega-aminoalkyl)-2,5,6,7-tetrahydropyrazolo[3,4,5-mn]pyrimido[5,6,1-de]acridine-5,7-diones: novel, potent, cytotoxic, and DNA-binding agents

artículo científico publicado en 2002

2-Phenylquinolones as inhibitors of the HIV-1 Tat-TAR interaction

artículo científico publicado en 2009

6-Aminoquinolones as new potential anti-HIV agents.

artículo científico publicado en 2000

A potentiometric and CD investigation on the conformational properties of poly(L-p-aminophenylalanine) in aqueous solution

artículo científico publicado en 1976

A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons.

artículo científico publicado en 1997

Adjustable 'cross-linking' of neighboring DNA molecules in liquid-crystalline dispersions through (daunomycin-copper) polymeric chelate complexes

scientific article published on 01 December 1996

Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives

artículo científico

Aminoacyl-anthraquinone conjugates as telomerase inhibitors: synthesis, biophysical and biological evaluation

artículo científico publicado en 2008

An X-ray study of poly(L-prolyl-L-alpha-phenylglycyl-L-proline)

artículo científico publicado en 1976

Anthracyclines: recent developments in their separation and quantitation

artículo científico publicado en 2001

Anticancer agents: towards the future.

artículo científico publicado en 2004

Antitumor AZA-anthrapyrazoles: biophysical and biochemical studies on 8- and 9-aza regioisomers

artículo científico publicado en 2004

Antitumor potential of aza-bioisosterism in anthracenedione-based drugs.

artículo científico publicado en 2004

Antiviral 6-amino-quinolones: molecular basis for potency and selectivity

artículo científico publicado en 2005

Antiviral properties of psoralen derivatives: a biological and physico-chemical investigation

artículo científico publicado en 1984

Antiviral properties of quinolone-based drugs.

artículo científico publicado en 2004

Assessment of gene promoter G‑quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells

artículo científico publicado en 2014

Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage

artículo científico publicado en 2012

Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity

artículo científico publicado en 2015

BINOL-amino acid conjugates as triggerable carriers of DNA-targeted potent photocytotoxic agents

artículo científico publicado en 2007

Benzo- and tetrahydrobenzo-psoralen congeners: DNA binding and photobiological properties

artículo científico publicado en 1993

Benzofurocoumarins: new monofunctional DNA-photobinding agents

artículo científico publicado en 1986

Bipyridyl ligands as photoactivatable mono- and bis-alkylating agents capable of DNA cross-linking

artículo científico publicado en 2006

Bis-phenanthroline derivatives as suitable scaffolds for effective G-quadruplex recognition

artículo científico publicado en 2010

Chromophore-modified antitumor anthracenediones: synthesis, DNA binding, and cytotoxic activity of 1,4-bis[(aminoalkyl)amino]benzo[g]-phthalazine-5,10-diones

artículo científico publicado en 1995

Ciprofloxacin affects conformational equilibria of DNA gyrase A in the presence of magnesium ions

artículo científico publicado en 2001

Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action.

artículo científico publicado en 2003

Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage

artículo científico publicado en 2006

Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage

artículo científico publicado en 2008

Concerted bis-alkylating reactivity of clerocidin towards unpaired cytosine residues in DNA.

artículo científico publicado en 2004

Conformation and stability of intramolecular telomeric G-quadruplexes: sequence effects in the loops

artículo científico publicado en 2013

Conformational drug determinants of the sequence specificity of drug-stimulated topoisomerase II DNA cleavage

scientific article published on 01 January 1994

Conformational properties of topoisomerase II inhibitors and sequence specificity of DNA cleavage

scientific article published on 01 September 1994

Conformational state of lacrimal proteins adsorbed on contact lenses

artículo científico publicado en 1985

Continuous mitoxantrone infusion in pretreated epithelial ovarian cancer

scientific article published on 01 January 1995

DNA gyrase requires DNA for effective two-site coordination of divalent metal ions: further insight into the mechanism of enzyme action.

artículo científico publicado en 2008

DNA topoisomerase II structures and anthracycline activity: insights into ternary complex formation.

artículo científico publicado en 2007

DNA-binding of water-soluble furocoumarins: a thermodynamic and conformational approach to understanding different biological effects.

artículo científico publicado en 1984

Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents

artículo científico publicado en 2003

Development of DNA topoisomerase-related therapeutics: a short perspective of new challenges

artículo científico publicado en 2004

Diethylaminopropionamido-hydroxy-anthraquinones as potential anticancer agents: synthesis and characterization

artículo científico publicado en 1989

Differential targeting of unpaired bases within duplex DNA by the natural compound clerocidin: a valuable tool to dissect DNA secondary structure

artículo científico publicado en 2012

Dinuclear Zn(2+) complexes of synthetic heptapeptides as artificial nucleases.

artículo científico publicado en 2001

Dissecting reactivity of clerocidin toward common buffer systems by means of selected drug analogues

artículo científico publicado en 2005

Do quinolones bind to DNA?

artículo científico publicado en 1988

Effect of G-quadruplex polymorphism on the recognition of telomeric DNA by a metal complex

artículo científico publicado en 2013

Effective DNA inhibitors of cathepsin g by in vitro selection

artículo científico publicado en 2008

Effects of calcium ions on the interactions between antithrombin and factor Xa mediated by variously sulfated, semisynthetic low-molecular-weight heparins

artículo científico publicado en 2002

Effects of common buffer systems on drug activity: the case of clerocidin.

artículo científico publicado en 2004

Effects of magnesium and related divalent metal ions in topoisomerase structure and function.

artículo científico publicado en 2009

Effects of sulfation on antithrombin-thrombin/factor Xa interactions in semisynthetic low molecular weight heparins

artículo científico publicado en 2001

Effects of tacrine upon murine neuroblastoma cells

scientific article published on 01 January 1995

Efficient plasmid DNA cleavage by a mononuclear copper(II) complex

artículo científico publicado en 2005

Ferric complexes of acetoacetyl derivatives of poly(L-lysine), poly(L-ornithine), and poly(L-diaminobutyric acid). I. Preparation and absorption properties in solution.

artículo científico publicado en 1976

Ferric complexes of acetoacetyl derivatives of poly(L-lysine), poly(L-ornithine), and poly(L-diaminobutyric acid). II. Conformational properties in solution. Evidence for a stereospecific complex formation

scientific article published on 01 November 1976

Folding versus charge: understanding selective target recognition by the thrombin aptamers.

artículo científico publicado en 2012

Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity

artículo científico publicado en 2013

G-quadruplexes in human promoters: A challenge for therapeutic applications.

artículo científico publicado en 2016

Heterocyclic dications as a new class of telomeric G-quadruplex targeting agents

artículo científico publicado en 2012

Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases

artículo científico publicado en 2007

In front of and behind the replication fork: bacterial type IIA topoisomerases.

artículo científico publicado en 2010

In vitro basis for schedule-dependent interaction between gemcitabine and topoisomerase-targeted drugs in the treatment of colorectal cancer

artículo científico publicado en 2006

In vitro selection of DNA aptamers that bind L-tyrosinamide

artículo científico publicado en 2001

Inflammatory cytokine expression following the use of bipolar electrocoagulation, ultracision harmonic scalpel and cold knife biopsy

artículo científico publicado en 2015

Inhibition of human immunodeficiency virus type 1 tat-trans-activation-responsive region interaction by an antiviral quinolone derivative

artículo científico publicado en 2004

Inhibitory effects of glycosaminoglycans on basal and stimulated transforming growth factor-β1 expression in mesangial cells: biochemical and structural considerations

artículo científico publicado en 2011

Interaction between second generation anthracyclines and DNA in the nucleosomal structure

artículo científico publicado en 1991

Interaction model for anthracycline activity against DNA topoisomerase II.

artículo científico publicado en 2004

Interaction of calcium ions with peptide hormones of the gastrin family

scientific article published on 01 November 1983

Interaction of metal ions with gastrointestinal hormones. Binding of Ca2+ to Nle11-minigastrin I

scientific article published on 01 September 1980

Interaction of metal ions with gastrointestinal hormones: binding studies of Mg++ to biologically active analogs of little gastrin and minigastrin

scientific article published on 01 July 1984

Interaction of nucleosomes with anthracycline antibiotics: relevance to anticancer activity

artículo científico publicado en 1988

Interactions of low-molecular-weight semi-synthetic sulfated heparins with human leukocyte elastase and human Cathepsin G.

artículo científico publicado en 2005

Intermolecular indole-imidazolium complexes. II. Interaction of a block copolymer (L-tryptophan)n-(gamma-ethyl-DL-glutamate)m with imidazolium hydrochloride and poly(L-histidine hydrochloride).

artículo científico publicado en 1977

Involvement of p53 in specific anti-neuroectodermal tumor activity of aloe-emodin ⬇️

artículo científico publicado en 2003

Letter: Optical activity of the charge-transfer complex between poly-L-histidine hydrochloride and indole

artículo científico publicado en 1975

Liquid-crystalline structure of nucleic acids: effect of antracycline drugs and copper ions

artículo científico publicado en 1997

Mapping drug interactions at the covalent topoisomerase II-DNA complex by bisantrene/amsacrine congeners.

artículo científico publicado en 1998

Mapping simocyclinone D8 interaction with DNA gyrase: evidence for a new binding site on GyrB.

artículo científico publicado en 2009

Metal Complexes of Poly(α-amino acids). A Potentiometric and Circular Dichroism Investigation of Cu(II) Complexes of Poly(L-lysine), Poly(L-ornithine), and Poly(L-diaminobutyric acid)1 ⬇️

artículo científico publicado el 1 de julio de 1977

Metal ion-mediated assembly of effective phenanthroline-based G-quadruplex ligands

artículo científico publicado en 2009

Mg 2+ -mediated binding of 6-Substituted quinolones to DNA: relevance to biological activity

artículo científico publicado en 1998

Modulation of antithrombin-protease interactions by semisynthetic low-molecular-weight heparins with different sulfation patterns

artículo científico publicado en 2003

Molecular Basis for Differential Recognition of G-Quadruplex versus Double-Helix DNA by Bis-Phenanthroline Metal Complexes.

artículo científico publicado en 2016

Naphthalene diimide scaffolds with dual reversible and covalent interaction properties towards G-quadruplex.

artículo científico publicado en 2011

New 1,4-anthracene-9,10-dione derivatives as potential anticancer agents

artículo científico publicado en 2000

New anthracenedione derivatives: interaction with DNA and biological effects

artículo científico publicado en 1983

New anthracenediones with potential anticancer activity: synthesis and characterization of bis-diethylaminopropionamido derivatives

artículo científico publicado en 1988

New anti-human immunodeficiency virus type 1 6-aminoquinolones: mechanism of action

artículo científico publicado en 2003

Ni2+ and Cu2+ complexes of a phenanthroline-based ligand bind to G-quadruplexes at non-overlapping sites

artículo científico publicado en 2013

Novel Ametantrone-Amsacrine Related Hybrids as Topoisomerase IIβ Poisons and Cytotoxic Agents

scientific article published on 17 July 2014

Novel pyrrolo[3,2-f]quinolines: synthesis and antiproliferative activity

artículo científico publicado en 2001

Novel symmetric and asymmetric DNA scission determinants for Streptococcus pneumoniae topoisomerase IV and gyrase are clustered at the DNA breakage site.

artículo científico publicado en 2005

On the mechanism of action of quinolone drugs

artículo científico publicado en 1993

On the oxy analogues to the 3 leads to 1 intramolecularly hydrogen-bonded peptide conformations

scientific article published on 01 May 1976

On the oxy analogues to the 4 leads to 1 intramolecularly hydrogen-bonded peptide conformations

artículo científico publicado en 1976

Peptidyl Anthraquinones as Potential Antineoplastic Drugs: Synthesis, DNA Binding, Redox Cycling, and Biological Activity

artículo científico publicado en 1996

Perylene side chains modulate G-quadruplex conformation in biologically relevant DNA sequences

artículo científico publicado en 2008

Pharmacokinetics of intraperitoneal hyperthermic perfusion with mitoxantrone in ovarian cancer

scientific article published on 01 January 2000

Phase I–II intraperitoneal mitoxantrone in advanced pretreated ovarian cancer

artículo científico publicado en 1993

Photobiological activity of 3,4'-dimethyl-8-methoxypsoralen, a linear furocoumarin with unusual DNA-binding properties

scientific article published on 01 September 1990

Photoreaction of psoralen derivatives with structurally organized DNA.

artículo científico publicado en 1987

Physicochemical properties, cytotoxic activity and topoisomerase II inhibition of 2,3-diaza-anthracenediones

scientific article published on 01 January 1997

Potent 6-Desfluoro-8-methylquinolones as New Lead Compounds in Antibacterial Chemotherapy1

artículo científico publicado en 1996

Preferred interaction of d-peptidyl-anthraquinones with double-stranded B-DNA

artículo científico publicado en 1997

Pyrrolo-quinoline derivatives as potential antineoplastic drugs

artículo científico publicado en 2000

Pyrrolocoumarin derivatives: DNA-binding properties

artículo científico publicado en 1988

Quantitation of camptothecin and related compounds

artículo científico publicado en 2001

Quinone methide generation via photoinduced electron transfer.

artículo científico publicado en 2011

Quinone methides tethered to naphthalene diimides as selective G-quadruplex alkylating agents.

artículo científico publicado en 2009

Rational design, synthesis, and DNA binding properties of novel sequence-selective peptidyl congeners of ametantrone.

artículo científico

Reactivity of clerocidin towards adenine: implications for base-modulated DNA damage

artículo científico publicado en 2009

Relevance of DNA binding to the mechanism of anti-herpesvirus activity of benzhydrazone

artículo científico publicado en 1993

Relevance of ionic effects on norfloxacin uptake by Escherichia coli

artículo científico publicado en 1990

Remarkable interference with telomeric function by a G-quadruplex selective bisantrene regioisomer.

artículo científico publicado en 2010

Screening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models.

artículo científico publicado en 2016

Sensing biological effectors through the response of bridged nucleic acids and polynucleotides fixed in liquid-crystalline dispersions

artículo científico publicado en 1998

Sequence specificity of psoralen photobinding to DNA: a quantitative approach

artículo científico publicado el 1 de diciembre de 1992

Sequence-specific interactions of drugs interfering with the topoisomerase-DNA cleavage complex

artículo científico publicado en 2002

Sequencing and G-quadruplex folding of the canine proto-oncogene KIT promoter region: might dog be used as a model for human disease?

artículo científico publicado en 2014

Simocyclinone D8 turns on against Gram-negative bacteria in a clinical setting.

artículo científico publicado en 2009

Solid-state and solution conformation of N-tert-butyloxycarbonyl-L-prolylglycine

artículo científico publicado en 1977

Solid-state infrared absorption spectra and chain arrangement in some synthetic homooligopeptides in the intermolecularly hydrogen-bonded pleated-sheet beta-conformation

artículo científico publicado en 1977

Somatostatin-28: a conformational analysis

scientific article published on 01 August 1981

Structural properties of hyaluronic acid in moderately concentrated solutions

scientific article published on 01 July 1986

Structure modifications of 6-aminoquinolones with potent anti-HIV activity

artículo científico publicado en 2004

Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives

artículo científico publicado en 2010

Synthesis and biological evaluation of 2-phenylquinolones targeted at Tat/TAR recognition.

artículo científico publicado en 2008

Synthesis and conformational properties of polypeptides containing long aliphatic side chains. Poly(Nepsilon-stearyl-L-lysine) and poly(Nepsilon-pelargonyl-L-lysine)

scientific article published on 01 January 1975

Synthesis and conformational studies in solution of sequential copolypeptides: poly(L-prolyl-L-alpha-phenylglycyl-L-proline).

artículo científico publicado en 1975

Synthesis and photobiological properties of 4-hydroxymethyl-4'-methylpsoralen derivatives

artículo científico publicado en 1993

Synthesis, DNA-damaging and cytotoxic properties of novel topoisomerase II-directed bisantrene analogues

scientific article published on 01 January 1998

Targeting loop adenines in G-quadruplex by a selective oxirane.

artículo científico publicado en 2012

The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein

artículo científico publicado en 2010

The Effects of Metal Ions on the Structure and Stability of the DNA Gyrase B Protein

artículo científico publicado en 2005

The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids

artículo científico publicado en 2016

The evolving world of protein-G-quadruplex recognition: a medicinal chemist's perspective.

artículo científico publicado en 2011

The peculiar binding properties of 4'-deoxy,4'-iododoxorubicin to isolated DNA and 175 bp nucleosomes

artículo científico publicado en 1991

The quinolone family: from antibacterial to anticancer agents

artículo científico publicado en 2003

Topoisomerase I involvement in schedule-dependent interaction between 5-fluoro-uracil and irinotecan in the treatment of colorectal cancer

artículo científico publicado en 2009

Topoisomerase I, IIα and IIβ mRNA expression in peripheral blood mononuclear cells of patients with solid tumor: preliminary results

artículo científico publicado en 2006

Toward efficient Zn(II)-based artificial nucleases

artículo científico publicado en 2004

Tri-, tetra- and heptacyclic perylene analogues as new potential antineoplastic agents based on DNA telomerase inhibition

artículo científico publicado en 2006

Tuning G-Quadruplex vs Double-Stranded DNA Recognition in Regioisomeric Lysyl-Peptidyl-Anthraquinone Conjugates ⬇️

artículo científico publicado el 28 de septiembre de 2011

Tuning the activity of Zn(II) complexes in DNA cleavage: clues for design of new efficient metallo-hydrolases

artículo científico publicado en 2008

Virtual Cross-Linking of the Active Nemorubicin Metabolite PNU-159682 to Double-Stranded DNA.

artículo científico publicado en 2017

Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: in vitro antiproliferative activity and molecular mechanism(s) of action.

artículo científico publicado en 2015

Lista de obras de Manlio Palumbo

2,6-Di(omega-aminoalkyl)-2,5,6,7-tetrahydropyrazolo[3,4,5-mn]pyrimido[5,6,1-de]acridine-5,7-diones: novel, potent, cytotoxic, and DNA-binding agents

2-Phenylquinolones as inhibitors of the HIV-1 Tat-TAR interaction

6-Aminoquinolones as new potential anti-HIV agents.

A potentiometric and CD investigation on the conformational properties of poly(L-p-aminophenylalanine) in aqueous solution

A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons.

Adjustable 'cross-linking' of neighboring DNA molecules in liquid-crystalline dispersions through (daunomycin-copper) polymeric chelate complexes

Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives

Aminoacyl-anthraquinone conjugates as telomerase inhibitors: synthesis, biophysical and biological evaluation

An X-ray study of poly(L-prolyl-L-alpha-phenylglycyl-L-proline)

Anthracyclines: recent developments in their separation and quantitation

Anticancer agents: towards the future.

Antitumor AZA-anthrapyrazoles: biophysical and biochemical studies on 8- and 9-aza regioisomers

Antitumor potential of aza-bioisosterism in anthracenedione-based drugs.

Antiviral 6-amino-quinolones: molecular basis for potency and selectivity

Antiviral properties of psoralen derivatives: a biological and physico-chemical investigation

Antiviral properties of quinolone-based drugs.

Assessment of gene promoter G‑quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells

Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage

Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity

BINOL-amino acid conjugates as triggerable carriers of DNA-targeted potent photocytotoxic agents

Benzo- and tetrahydrobenzo-psoralen congeners: DNA binding and photobiological properties

Benzofurocoumarins: new monofunctional DNA-photobinding agents

Bipyridyl ligands as photoactivatable mono- and bis-alkylating agents capable of DNA cross-linking

Bis-phenanthroline derivatives as suitable scaffolds for effective G-quadruplex recognition

Chromophore-modified antitumor anthracenediones: synthesis, DNA binding, and cytotoxic activity of 1,4-bis[(aminoalkyl)amino]benzo[g]-phthalazine-5,10-diones

Ciprofloxacin affects conformational equilibria of DNA gyrase A in the presence of magnesium ions

Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action.

Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage

Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage

Concerted bis-alkylating reactivity of clerocidin towards unpaired cytosine residues in DNA.

Conformation and stability of intramolecular telomeric G-quadruplexes: sequence effects in the loops

Conformational drug determinants of the sequence specificity of drug-stimulated topoisomerase II DNA cleavage

Conformational properties of topoisomerase II inhibitors and sequence specificity of DNA cleavage

Conformational state of lacrimal proteins adsorbed on contact lenses

Continuous mitoxantrone infusion in pretreated epithelial ovarian cancer

DNA gyrase requires DNA for effective two-site coordination of divalent metal ions: further insight into the mechanism of enzyme action.

DNA topoisomerase II structures and anthracycline activity: insights into ternary complex formation.

DNA-binding of water-soluble furocoumarins: a thermodynamic and conformational approach to understanding different biological effects.

Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents

Development of DNA topoisomerase-related therapeutics: a short perspective of new challenges

Diethylaminopropionamido-hydroxy-anthraquinones as potential anticancer agents: synthesis and characterization

Differential targeting of unpaired bases within duplex DNA by the natural compound clerocidin: a valuable tool to dissect DNA secondary structure

Dinuclear Zn(2+) complexes of synthetic heptapeptides as artificial nucleases.

Dissecting reactivity of clerocidin toward common buffer systems by means of selected drug analogues

Do quinolones bind to DNA?

Effect of G-quadruplex polymorphism on the recognition of telomeric DNA by a metal complex

Effective DNA inhibitors of cathepsin g by in vitro selection

Effects of calcium ions on the interactions between antithrombin and factor Xa mediated by variously sulfated, semisynthetic low-molecular-weight heparins

Effects of common buffer systems on drug activity: the case of clerocidin.

Effects of magnesium and related divalent metal ions in topoisomerase structure and function.

Effects of sulfation on antithrombin-thrombin/factor Xa interactions in semisynthetic low molecular weight heparins

Effects of tacrine upon murine neuroblastoma cells

Efficient plasmid DNA cleavage by a mononuclear copper(II) complex

Ferric complexes of acetoacetyl derivatives of poly(L-lysine), poly(L-ornithine), and poly(L-diaminobutyric acid). I. Preparation and absorption properties in solution.

Ferric complexes of acetoacetyl derivatives of poly(L-lysine), poly(L-ornithine), and poly(L-diaminobutyric acid). II. Conformational properties in solution. Evidence for a stereospecific complex formation

Folding versus charge: understanding selective target recognition by the thrombin aptamers.

Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity

G-quadruplexes in human promoters: A challenge for therapeutic applications.

Heterocyclic dications as a new class of telomeric G-quadruplex targeting agents

Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases

In front of and behind the replication fork: bacterial type IIA topoisomerases.

In vitro basis for schedule-dependent interaction between gemcitabine and topoisomerase-targeted drugs in the treatment of colorectal cancer

In vitro selection of DNA aptamers that bind L-tyrosinamide

Inflammatory cytokine expression following the use of bipolar electrocoagulation, ultracision harmonic scalpel and cold knife biopsy

Inhibition of human immunodeficiency virus type 1 tat-trans-activation-responsive region interaction by an antiviral quinolone derivative

Inhibitory effects of glycosaminoglycans on basal and stimulated transforming growth factor-β1 expression in mesangial cells: biochemical and structural considerations

Interaction between second generation anthracyclines and DNA in the nucleosomal structure

Interaction model for anthracycline activity against DNA topoisomerase II.

Interaction of calcium ions with peptide hormones of the gastrin family

Interaction of metal ions with gastrointestinal hormones. Binding of Ca2+ to Nle11-minigastrin I

Interaction of metal ions with gastrointestinal hormones: binding studies of Mg++ to biologically active analogs of little gastrin and minigastrin

Interaction of nucleosomes with anthracycline antibiotics: relevance to anticancer activity

Interactions of low-molecular-weight semi-synthetic sulfated heparins with human leukocyte elastase and human Cathepsin G.

Intermolecular indole-imidazolium complexes. II. Interaction of a block copolymer (L-tryptophan)n-(gamma-ethyl-DL-glutamate)m with imidazolium hydrochloride and poly(L-histidine hydrochloride).

Involvement of p53 in specific anti-neuroectodermal tumor activity of aloe-emodin ⬇️

Letter: Optical activity of the charge-transfer complex between poly-L-histidine hydrochloride and indole

Liquid-crystalline structure of nucleic acids: effect of antracycline drugs and copper ions

Mapping drug interactions at the covalent topoisomerase II-DNA complex by bisantrene/amsacrine congeners.

Mapping simocyclinone D8 interaction with DNA gyrase: evidence for a new binding site on GyrB.