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Lista de obras de Harald H Sitte

'Second-generation' mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function

artículo científico publicado en 2014

A Novel Heterocyclic Compound CE-104 Enhances Spatial Working Memory in the Radial Arm Maze in Rats and Modulates the Dopaminergic System.

artículo científico publicado en 2016

A binding mode hypothesis of tiagabine confirms liothyronine effect on γ-aminobutyric acid transporter 1 (GAT1)

artículo científico publicado en 2015

A combined approach using transporter-flux assays and mass spectrometry to examine psychostimulant street drugs of unknown content

artículo científico publicado en 2012

A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter

artículo científico publicado en 2014

A heterocyclic compound CE-103 inhibits dopamine reuptake and modulates dopamine transporter and dopamine D1-D3 containing receptor complexes

artículo científico publicado en 2015

A membrane network of receptors and enzymes for adenine nucleotides and nucleosides.

artículo científico publicado en 2008

A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities

artículo científico publicado en 2014

A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter

artículo científico publicado en 2015

A secretagogin locus of the mammalian hypothalamus controls stress hormone release

artículo científico publicado en 2014

Actovegin®: a biological drug for more than 5 decades ⬇️

artículo científico publicado el 1 de febrero de 2011

Additive gene-environment effects on hippocampal structure in healthy humans

artículo científico publicado en 2014

Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters

artículo científico publicado en 2013

Amphetamine action at the cocaine- and antidepressant-sensitive serotonin transporter is modulated by αCaMKII.

artículo científico publicado en 2015

Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate

artículo científico publicado en 2013

Amphetamine reverses or blocks the operation of the human noradrenaline transporter depending on its concentration: superfusion studies on transfected cells

artículo científico publicado en 1999

Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action

Amphetamines, new psychoactive drugs and the monoamine transporter cycle.

artículo científico publicado en 2014

An electrophoretic approach to screen for glutamine deamidation.

artículo científico publicado en 2012

An unsuspected role for organic cation transporter 3 in the actions of amphetamine

artículo científico publicado en 2018

Are reprogrammed cells a useful tool for studying dopamine dysfunction in psychotic disorders? A review of the current evidence

artículo científico publicado en 2016

Autoradiography with [3H]PK11195 of spinal tract degeneration in amyotrophic lateral sclerosis.

artículo científico publicado en 2001

Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum

artículo científico publicado en 2014

Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1

artículo científico publicado en 2002

Binding Mode Selection Determines the Action of Ecstasy Homologs at Monoamine Transporters

artículo científico publicado en 2015

Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.

artículo científico publicado en 2012

Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport.

artículo científico publicado en 2006

Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter.

artículo científico publicado en 1998

Characterization of carrier-mediated efflux in human embryonic kidney 293 cells stably expressing the rat serotonin transporter: a superfusion study.

artículo científico publicado en 2000

Concentrative export from the endoplasmic reticulum of the gamma-aminobutyric acid transporter 1 requires binding to SEC24D.

artículo científico publicado en 2007

Cooperativity between individual transporter protomers: new data fuelling old complexes

artículo científico publicado en 2015

DARK Classics in Chemical Neuroscience: Aminorex Analogues

artículo científico publicado en 2018

Dephosphorylation of human dopamine transporter at threonine 48 by protein phosphatase PP1/2A up-regulates transport velocity

scientific article published on 26 December 2018

Differential regulation of amphetamine-induced serotonergic and dopaminergic efflux by syntaxin 1A.

artículo científico publicado en 2011

Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter

artículo científico publicado en 2017

Dopamine Transporter Phosphorylation Site Threonine 53 Regulates Substrate Reuptake and Amphetamine-stimulated Efflux ⬇️

artículo científico publicado el 21 de junio de 2012

Dopamine and noradrenaline, but not serotonin, in the human claustrum are greatly reduced in patients with Parkinson's disease: possible functional implications

artículo científico publicado en 2016

Dopamine transporter forms stable dimers in the live cell plasma membrane in a phosphatidylinositol 4,5-bisphosphate-independent manner

artículo científico publicado en 2019

Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain.

artículo científico publicado en 2018

Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact

artículo científico publicado en 2020

Dual Action of Zn2+ on the Transport Cycle of the Dopamine Transporter.

artículo científico publicado en 2015

Enhanced serotonin transporter function during depression in seasonal affective disorder

artículo científico publicado en 2007

Evidence for a role of transporter-mediated currents in the depletion of brain serotonin induced by serotonin transporter substrates

artículo científico publicado en 2013

Fluorescence resonance energy transfer in the study of cancer pathways

artículo científico publicado en 2003

Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family

artículo científico publicado en 2017

GTRAP3-18 serves as a negative regulator of Rab1 in protein transport and neuronal differentiation.

artículo científico publicado en 2008

Globus pallidus dopamine and Parkinson motor subtypes: clinical and brain biochemical correlation

artículo científico publicado en 2008

Glycine transporter dimers: evidence for occurrence in the plasma membrane

artículo científico publicado en 2008

Guidelines for vaccination of immunocompromised individuals

artículo científico publicado en 2016

Heterocyclic Analogues of Modafinil as Novel, Atypical Dopamine Transporter Inhibitors.

artículo científico publicado en 2017

Human brain dopamine metabolism in levodopa-induced dyskinesia and wearing-off

artículo científico publicado en 2004

Identification of an additional interaction domain in transmembrane domains 11 and 12 that supports oligomer formation in the human serotonin transporter.

artículo científico publicado en 2003

Imaging genetics of mood disorders.

artículo científico publicado en 2010

Impact of oligomerization on the function of the human serotonin transporter.

artículo científico publicado en 2001

In vivo amphetamine action is contingent on αCaMKII

artículo científico publicado en 2014

Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters

artículo científico publicado en 2020

Insights into binding events of GABA- and Tiagabine- analogues in the Gamma-Aminobutyric Acid Transporter 1 by means of Molecular Modelling.

artículo científico publicado en 2012

Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8.

artículo científico publicado en 2005

Involvement of serotonin transporter extracellular loop 1 in serotonin binding and transport.

artículo científico publicado en 2008

LAPTM4A interacts with hOCT2 and regulates its endocytotic recruitment

artículo científico publicado en 2011

Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction

artículo científico publicado en 2015

Making Sense of: Sensitization in Schizophrenia

artículo científico publicado en 2016

Membrane localization is critical for activation of the PICK1 BAR domain

artículo científico publicado en 2008

Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.

artículo científico publicado en 2013

Methamphetamine ("crystal meth") causes induction of DNA damage and chromosomal aberrations in human derived cells

scientific article published on 22 March 2019

Missense dopamine transporter mutations associate with adult parkinsonism and ADHD.

artículo científico publicado en 2014

Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model

artículo científico publicado en 2013

Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.

artículo científico publicado en 2010

Mutations within an intramembrane leucine heptad repeat disrupt oligomer formation of the rat GABA transporter 1.

artículo científico publicado en 2002

N,N-dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents.

artículo científico publicado en 2008

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites

artículo científico publicado en 2015

Oligomer formation by Na+-Cl--coupled neurotransmitter transporters.

artículo científico publicado en 2003

Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells.

artículo científico publicado en 2000

Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II

artículo científico publicado en 2004

On the relationship of first-episode psychosis to the amphetamine-sensitized state: a dopamine D2/3 receptor agonist radioligand study

scientific article published on 08 January 2020

Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults

artículo científico publicado en 2014

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

artículo científico publicado en 2014

Pairwise structural comparison of tiagabine analogs gives new insights into their protein binding modes.

artículo científico publicado en 2013

Peptide-based interactions with calnexin target misassembled membrane proteins into endoplasmic reticulum-derived multilamellar bodies

artículo científico publicado en 2008

Pharmacological examination of trifluoromethyl ring-substituted methcathinone analogs

artículo científico publicado en 2012

Phase I metabolites of mephedrone display biological activity as substrates at monoamine transporters.

scientific article published on 08 July 2016

Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3

scientific journal article

Platelet serotonin transporter function predicts default-mode network activity

artículo científico publicado en 2014

Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products

artículo científico publicado en 2012

Probing binding pocket of serotonin transporter by single molecular force spectroscopy on living cells.

artículo científico publicado en 2011

Probing the Selectivity of Monoamine Transporter Substrates by Means of Molecular Modeling

artículo científico publicado en 2013

Quantitative analysis of inward and outward transport rates in cells stably expressing the cloned human serotonin transporter: inconsistencies with the hypothesis of facilitated exchange diffusion

artículo científico publicado en 2001

Reduced default mode network suppression during a working memory task in remitted major depression

artículo científico publicado en 2015

Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site

artículo científico publicado en 2015

Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1.

artículo científico publicado en 2007

SLC6 transporter oligomerization

artículo científico publicado en 2020

Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism.

artículo científico publicado en 2014

Sec24- and ARFGAP1-dependent trafficking of GABA transporter-1 is a prerequisite for correct axonal targeting.

artículo científico publicado en 2008

Selective serotonin reuptake inhibitors--a new modality for the treatment of lymphoma/leukaemia?

artículo científico publicado en 2007

Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines and non-amphetamines

artículo científico publicado en 2005

Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation

artículo científico publicado en 2014

Signal-dependent export of GABA transporter 1 from the ER-Golgi intermediate compartment is specified by a C-terminal motif

artículo científico publicado en 2008

Single molecule analysis reveals coexistence of stable serotonin transporter monomers and oligomers in the live cell plasma membrane.

scientific article published on 06 January 2014

Sodium-dependent neurotransmitter transporters: oligomerization as a determinant of transporter function and trafficking

artículo científico publicado en 2004

Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3

scientific article published on 12 February 2019

Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.

artículo científico publicado en 2014

Structure-Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters

scientific article published on 30 December 2019

Substantial loss of substrate by diffusion during uptake in HEK-293 cells expressing neurotransmitter transporters.

artículo científico publicado en 2001

Subtype-specific differences in corticotropin-releasing factor receptor complexes detected by fluorescence spectroscopy

artículo científico publicado en 2009

Sustained dopamine release induced by secretoneurin in the striatum of the rat: a microdialysis study

artículo científico publicado en 1995

Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C

artículo científico publicado en 2013

Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers.

artículo científico publicado en 2016

The Environment Shapes the Inner Vestibule of LeuT.

artículo científico publicado en 2016

The N terminus of monoamine transporters is a lever required for the action of amphetamines

artículo científico publicado en 2010

The Plasma Membrane-Associated GTPase Rin Interacts with the Dopamine Transporter and Is Required for Protein Kinase C-Regulated Dopamine Transporter Trafficking ⬇️

artículo científico publicado el 28 de septiembre de 2011

The conservative view: is it necessary to implant a stent into the dopamine transporter?

artículo científico publicado en 2014

The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle.

artículo científico publicado en 2006

The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization

artículo científico publicado en 2011

The effect of modafinil on the rat dopamine transporter and dopamine receptors D1-D3 paralleling cognitive enhancement in the radial arm maze

artículo científico publicado en 2015

The endoplasmic reticulum exit of glutamate transporter is regulated by the inducible mammalian Yip6b/GTRAP3-18 protein

artículo científico publicado en 2007

The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter

artículo científico publicado en 2010

The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization

scientific journal article

The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters

artículo científico publicado en 2012

The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters--why amphetamines take two to tango.

artículo científico publicado en 2009

The role of zinc ions in reverse transport mediated by monoamine transporters.

artículo científico publicado en 2002

The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

artículo científico publicado en 2011

The two Na+ sites in the human serotonin transporter play distinct roles in the ion coupling and electrogenicity of transport

artículo científico publicado en 2013

Tracking single serotonin transporter molecules at the endoplasmic reticulum and plasma membrane

artículo científico publicado en 2014

Transition metal ion FRET uncovers K(+) regulation of a neurotransmitter/sodium symporter.

scientific article published on 28 September 2016

Transporter-mediated release: a superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter

artículo científico publicado en 2000

Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1)

scientific journal article

Unifying concept of serotonin transporter-associated currents

artículo científico publicado en 2011

Zinc potentiates an uncoupled anion conductance associated with the dopamine transporter

artículo científico publicado en 2004

para-Trifluoromethyl-methcathinone is an allosteric modulator of the serotonin transporter

artículo científico publicado en 2019

α-Fluorination of carbonyls with nucleophilic fluorine

artículo científico publicado en 2019

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