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Lista de obras de Richie Soong

A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting

scientific article published on 08 October 2009

A warfarin-dosing model in Asians that uses single-nucleotide polymorphisms in vitamin K epoxide reductase complex and cytochrome P450 2C9.

artículo científico publicado en 2006

ADPRT Val762Ala and XRCC1 Arg194Trp Polymorphisms and Risk of Gastric Cancer in Sichuan of China

artículo científico publicado el 1 de enero de 2012

Advances and challenges in fluoropyrimidine pharmacogenomics and pharmacogenetics.

artículo científico publicado en 2005

An improved quality control for bisulfite-PCR-based DNA methylation analysis: cycle threshold value

artículo científico publicado en 2008

Association of the IL-1B +3954 C/T polymorphism with the risk of gastric cancer in a population in Western China.

artículo científico publicado en 2014

BRAF mutation is associated with the CpG island methylator phenotype in colorectal cancer from young patients

artículo científico publicado en 2008

Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

artículo científico publicado en 2008

CD133 expression predicts for non-response to chemotherapy in colorectal cancer

artículo científico publicado en 2010

CYP3A5*3 and bilirubin predict midazolam population pharmacokinetics in Asian cancer patients

artículo científico publicado en 2013

Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies?

artículo científico publicado en 2012

Clinical and therapeutic relevance of PIM1 kinase in gastric cancer

artículo científico publicado en 2011

Clinical potential of DNA methylation in gastric cancer: a meta-analysis

artículo científico publicado en 2012

Clonal characterization of sporadic cribriform-morular variant of papillary thyroid carcinoma by laser microdissection-based APC mutation analysis

artículo científico publicado en 2007

Comparison of the pharmacokinetics and pharmacodynamics of S-1 between Caucasian and East Asian patients

scientific article published on 10 December 2010

Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features

artículo científico publicado en 2010

Computer-assisted pathological immunohistochemistry scoring is more time-effective than conventional scoring, but provides no analytical advantage

artículo científico publicado en 2010

Concordance between p53 protein overexpression and gene mutation in a large series of common human carcinomas

artículo científico publicado en 1996

Correlation between epidermal growth factor receptor mutations and expression of female hormone receptors in East-Asian lung adenocarcinomas.

artículo científico publicado en 2010

Correlation of aldo-ketoreductase (AKR) 1C3 genetic variant with doxorubicin pharmacodynamics in Asian breast cancer patients.

artículo científico publicado en 2013

DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach.

artículo científico publicado en 2014

Dasatinib induces a response in malignant thymoma

artículo científico publicado en 2006

Dedifferentiated liposarcoma with unusual kaposiform morphology and whorl formation masquerading As Kaposi's sarcoma: diagnostically challenging case confirmed by cytogenetic and TP53 mutation analysis.

artículo científico publicado en 2013

Dedifferentiated solitary fibrous tumour of the nasal cavity: the first case reported with molecular characterization of a TP53 mutation

artículo científico publicado en 2011

Deep whole-genome sequencing of 100 southeast Asian Malays

artículo científico publicado en 2013

Denaturing high performance liquid chromatography for the detection of microsatellite instability using bethesda and pentaplex marker panels.

artículo científico publicado en 2008

Detection of BRAF V600E mutation by pyrosequencing

artículo científico publicado en 2008

Detection of epidermal growth factor receptor variations by partially denaturing HPLC.

artículo científico publicado en 2006

Detection of p53 gene mutation by rapid PCR-SSCP and its association with poor survival in breast cancer

artículo científico publicado en 1997

Determination of a molecular signature of acute T-cell-mediated renal allograft rejection using quantitative real-time RT-PCR of 45 genes on a low density array.

artículo científico publicado en 2011

Differences in outcome and toxicity between Asian and caucasian patients with lung cancer treated with systemic therapy.

artículo científico publicado en 2012

Distribution of gemcitabine pathway genotypes in ethnic Asians and their association with outcome in non-small cell lung cancer patients

artículo científico publicado en 2008

E1A-F is overexpressed early in human colorectal neoplasia and associated with cyclooxygenase-2 and matrix metalloproteinase-7.

artículo científico publicado en 2005

Effect of blood sample handling and reverse transcriptase-polymerase chain reaction assay sensitivity on detection of CK20 expression in healthy donor blood

scientific article published on 01 June 2002

Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.

artículo científico publicado en 2008

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

artículo científico publicado en 2015

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

artículo científico publicado en 2016

Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.

artículo científico publicado en 2008

Ethnic differences in survival outcome in patients with advanced stage non-small cell lung cancer: results of a meta-analysis of randomized controlled trials.

artículo científico publicado en 2011

Evidence for disease control with erlotinib after gefitinib failure in typical gefitinib-sensitive Asian patients with non-small cell lung cancer

artículo científico publicado en 2008

Exome sequencing: dual role as a discovery and diagnostic tool

artículo científico publicado en 2012

Exome versus transcriptome sequencing in identifying coding region variants

artículo científico

Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study.

artículo científico publicado en 2006

GBSA: a comprehensive software for analysing whole genome bisulfite sequencing data.

artículo científico publicado en 2012

Gastric carcinomas with microsatellite instability: clinical features and mutations to the TGF-beta type II receptor, IGFII receptor, and BAX genes

artículo científico publicado en 1999

Gene discovery in familial cancer syndromes by exome sequencing: prospects for the elucidation of familial colorectal cancer type X.

artículo científico publicado en 2012

Genetic factors associated with intestinal metaplasia in a high risk Singapore-Chinese population: a cohort study

artículo científico publicado en 2009

Human genetics and genomics a decade after the release of the draft sequence of the human genome

artículo científico publicado en 2011

Identification of potentially useful combinations of epidermal growth factor receptor tyrosine kinase antagonists with conventional cytotoxic agents using median effect analysis

artículo científico publicado en 2006

Immunotherapy in the treatment of non-small cell lung cancer

artículo científico publicado en 2014

Impact of sample heterogeneity on methylation analysis

scientific article published on 01 December 2010

Implications of dihydropyrimidine dehydrogenase on 5-fluorouracil pharmacogenetics and pharmacogenomics.

artículo científico publicado en 2002

Improved indicators for assessing the reliability of detection and quantification by kinetic PCR

artículo científico publicado en 2003

Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype.

artículo científico publicado en 2014

Insights into the genetic structure and diversity of 38 South Asian Indians from deep whole-genome sequencing

artículo científico publicado en 2014

Interethnic variability of warfarin maintenance requirement is explained by VKORC1 genotype in an Asian population

artículo científico publicado en 2006

Interleukin-10 Gene Promoter Polymorphisms and Risk of Gastric Cancer in a Chinese Population: Single Nucleotide and Haplotype Analyses

artículo científico publicado el 1 de enero de 2013

KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma.

artículo científico publicado en 2010

KRAS mutation analysis in a complex molecular diagnostic referral practice: the need for test redundancy

artículo científico publicado en 2012

Localized sclerotic bone response demonstrated reduced nanomechanical creep properties.

artículo científico publicado en 2012

Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer.

artículo científico publicado en 2011

Lymphocytic follicles and aggregates are a determinant of mucosal damage and duration of diarrhea

artículo científico publicado en 2013

Meta-analysis of genetic polymorphisms and gastric cancer risk: variability in associations according to race

artículo científico publicado en 2009

MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancer

artículo científico publicado en 2010

Molecular characterization of dedifferentiated mucoepidermoid carcinoma of the trachea using laser microdissection-based TP53 mutation analysis

artículo científico publicado en 2009

Molecular gene expression signature patterns for gastric cancer diagnosis

artículo científico publicado en 2007

Mutation of the transforming growth factor-beta type II receptor gene in right-sided colorectal cancer: relationship to clinicopathological features and genetic alterations

artículo científico publicado en 1998

Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracil–based chemotherapy.

artículo científico publicado en 2014

Patz1 regulates embryonic stem cell identity.

artículo científico

Pharmacodynamic effects of seliciclib, an orally administered cell cycle modulator, in undifferentiated nasopharyngeal cancer

artículo científico publicado en 2009

Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-fluorouracil in PIK3CA mutant gastric cancer cells.

artículo científico publicado en 2012

Phase II evaluation of docetaxel-modulated capecitabine in previously treated patients with non-small cell lung cancer

artículo científico publicado en 2005

Phosphatidylinositol-3-kinase pathway aberrations in gastric and colorectal cancer: meta-analysis, co-occurrence and ethnic variation

artículo científico publicado en 2013

Polymorphisms of XRCC1 and ADPRT Genes and Risk of Noncardia Gastric Cancer in a Chinese Population: a Case-control Study

artículo científico publicado el 1 de enero de 2012

Postoperative serum methylation levels of TAC1 and SEPT9 are independent predictors of recurrence and survival of patients with colorectal cancer

artículo científico publicado en 2014

Primary mucinous adenocarcinoma of the epididymis: report of a rare case with molecular genetic characterization including mutation analysis of the TP53 gene

artículo científico publicado en 2015

Prognostic significance of TP53 gene mutation in 995 cases of colorectal carcinoma. Influence of tumour site, stage, adjuvant chemotherapy and type of mutation

artículo científico publicado en 2000

Protein arginine methyltransferase 6 regulates embryonic stem cell identity

artículo científico publicado en 2012

Quantitative detection of cytokeratin 20 mRNA expression in bladder carcinoma by real-time reverse transcriptase-polymerase chain reaction

artículo científico publicado en 2004

RUNX3 downregulation in human lung adenocarcinoma is independent of p53, EGFR or KRAS status.

artículo científico publicado en 2012

RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression.

artículo científico publicado en 2008

RUNX3 inactivation in colorectal polyps arising through different pathways of colonic carcinogenesis

artículo científico publicado en 2009

RUNX3 protein is overexpressed in human basal cell carcinomas

artículo científico publicado en 2006

Response to a novel multitargeted tyrosine kinase inhibitor pazopanib in metastatic Merkel cell carcinoma.

artículo científico publicado en 2009

Simultaneous detection of variable number tandem repeats, single nucleotide polymorphisms, and allelic imbalance in the thymidylate synthase gene enhancer region using denaturing high-performance liquid chromatography

artículo científico publicado en 2004

Studying the epigenome using next generation sequencing

artículo científico publicado en 2011

TRARESA: a tissue microarray-based hospital system for biomarker validation and discovery.

artículo científico publicado en 2008

Targeting ROS1 with anaplastic lymphoma kinase inhibitors: a promising therapeutic strategy for a newly defined molecular subset of non-small-cell lung cancer.

artículo científico publicado en 2012

Technological advances in DNA sequence enrichment and sequencing for germline genetic diagnosis

artículo científico publicado en 2012

The common molecular genetic alterations in Dukes' B and C colorectal carcinomas are not short-term prognostic indicators of survival

scientific article published on 01 December 1994

The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome.

artículo científico publicado en 2009

The positive impact of cytological specimens for EGFR mutation testing in non-small cell lung cancer: a single South East Asian laboratory's analysis of 670 cases

artículo científico publicado en 2012

The topography of DNA methylation in the non-neoplastic colonic mucosa surrounding colorectal cancers

artículo científico publicado en 2012

Thrombomodulin expression in gastrointestinal stromal tumours (GISTs): a novel finding with diagnostic implications

artículo científico publicado en 2009

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

artículo científico publicado en 2013

Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer

artículo científico publicado en 2005

Use of intraoperative cell-salvage for autologous blood transfusions in metastatic spine tumour surgery: a systematic review.

artículo científico publicado en 2014

Whole-genome reconstruction and mutational signatures in gastric cancer.

artículo científico publicado en 2012

p53 accumulation and mutation are prognostic indicators of poor survival in human gastric carcinoma

artículo científico publicado en 1996

p53 protein overexpression and gene mutation in mixed Müllerian tumors of the uterus

artículo científico publicado en 1999