Lista de obras - Norman L. Lehman - Dominio Público Uruguay

1H MRS in acute traumatic brain injury.

artículo científico publicado en 1998

Anaplastic papillary glioneuronal tumor with extraneural metastases

artículo científico publicado en 2014

Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes

artículo científico publicado en 2022

Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas ⬇️

artículo científico publicado el 1 de febrero de 2012

Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma.

artículo científico publicado en 2014

Axonal Outgrowth and Dendritic Plasticity in the Cortical Peri-Infarct Area After Experimental Stroke ⬇️

artículo científico publicado el 22 de mayo de 2012

Can permeability measurements add to blood volume measurements in differentiating tumefactive demyelinating lesions from high grade gliomas using perfusion CT?

artículo científico publicado en 2009

Case report: ACTH-secreting pituitary carcinoma metastatic to the liver in a patient with a history of atypical pituitary adenoma and Cushing's disease

artículo científico publicado en 2017

Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies

artículo científico publicado en 2014

Characterizing brain structures and remodeling after TBI based on information content, diffusion entropy

artículo científico publicado en 2013

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

artículo científico

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Cortical ependymoma. A case report and review

artículo científico publicado en 2003

Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells

scientific article published on 22 April 2019

Differential expression of aurora-A kinase in T-cell lymphomas.

artículo científico publicado en 2013

Dural marginal zone lymphoma with massive amyloid deposition: rare low-grade primary central nervous system B-cell lymphoma. Case report

artículo científico publicado en 2002

EXTH-75. THE AURORA KINASE A INHIBITOR ALISERTIB IS SYNERGISTIC WITH IRINOTECAN AND CARBOPLATIN AGAINST GLIOBLASTOMA CELLS

artículo científico publicado en 2018

Early neonatal diagnosis of long-chain 3-hydroxyacyl coenzyme a dehydrogenase and mitochondrial trifunctional protein deficiencies.

artículo científico publicado en 2002

Emi1 protein accumulation implicates misregulation of the anaphase promoting complex/cyclosome pathway in ovarian clear cell carcinoma

artículo científico publicado en 2008

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

artículo científico publicado en 2006

Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis

Glioblastoma cell enrichment is critical for analysis of phosphorylated drug targets and proteomic-genomic correlations

artículo científico publicado en 2013

Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo

artículo científico publicado en 2010

Gliosarcoma with melanocytic differentiation

artículo científico publicado en 2007

Histologic findings of disc, end plate and neural elements after coblation of nucleus pulposus: an experimental nucleoplasty study.

artículo científico publicado en 2003

Histological predictors of outcome in ependymoma are dependent on anatomic site within the central nervous system

artículo científico publicado en 2013

Holoprosencephaly associated with an apparent isolated 2q37.1-->2q37.3 deletion

artículo científico publicado en 2001

Intramedullary papillary ependymoma with choroid plexus differentiation and cerebrospinal fluid dissemination to the brain

artículo científico publicado en 2010

Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence.

artículo científico publicado en 2007

Malignant PEComa of the skull base

artículo científico publicado en 2004

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

artículo científico

Morphological and molecular features of astroblastoma, including BRAFV600E mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults

artículo científico

NHERF1/EBP50 and NF2 as diagnostic markers for choroid plexus tumors

artículo científico publicado en 2016

Non-lysosomal cycling pathway for atrial natriuretic peptide activated by protein kinase C in human NPE cells

artículo científico publicado en 1998

Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors.

artículo científico publicado en 2007

Overview of Molecular Signal Transduction of Malignant Gliomas and Correlation with Responses to Targeted Therapy Recent advances in Molecular Characterization of Glioblastoma

PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance

scientific article published in Nature Communications

Patterns of brain infiltration and secondary structure formation in supratentorial ependymal tumors

artículo científico publicado en 2008

Pituitary carcinomas: review of the current literature and report of atypical case

scientific article published on 05 March 2019

Predicting survival in glioblastomas using diffusion tensor imaging metrics.

artículo científico publicado en 2010

Primary Meningeal Pleomorphic Xanthoastrocytoma With Anaplastic Features: A Report of 2 Cases, One With BRAF(V600E) Mutation and Clinical Response to the BRAF Inhibitor Dabrafenib

artículo científico publicado en 2015

Primary paraspinal leiomyosarcoma invading the cervical spinal canal successfully treated with surgery, radiotherapy, and chemotherapy. Case report

artículo científico publicado en 2007

Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair

artículo científico publicado en 2018

RARE-18EXCEPTIONAL RESPONDERS: A PERSONALIZED APPROACH TO TARGETED TREATMENT OF UNCOMMON BRAIN TUMORS.

artículo científico publicado en 2015

Radiation necrosis mimicking rapid intracranial progression of melanoma metastasis in two patients treated with vemurafenib.

artículo científico publicado en 2014

Screening of tissue microarrays for ubiquitin proteasome system components in tumors

artículo científico publicado en 2005

Splenic infarction evidenced by whole-body Tc-99m HMPAO-labeled leukocyte scan

artículo científico publicado en 1999

Synchronous subarachnoid drop metastases from a pituitary adenoma with multiple recurrences ⬇️

artículo científico publicado el 1 de mayo de 2003

The CNS penetrating taxane TPI 287 and the AURKA inhibitor alisertib induce synergistic apoptosis in glioblastoma cells

artículo científico publicado en 2018

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation

artículo científico publicado en 2014

The ubiquitin proteasome system in neuropathology

artículo científico publicado en 2009

Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class

artículo científico publicado en 2013

Lista de obras de Norman L. Lehman

1H MRS in acute traumatic brain injury.

Anaplastic papillary glioneuronal tumor with extraneural metastases

Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes

Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas ⬇️

Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma.

Axonal Outgrowth and Dendritic Plasticity in the Cortical Peri-Infarct Area After Experimental Stroke ⬇️

Can permeability measurements add to blood volume measurements in differentiating tumefactive demyelinating lesions from high grade gliomas using perfusion CT?

Case report: ACTH-secreting pituitary carcinoma metastatic to the liver in a patient with a history of atypical pituitary adenoma and Cushing's disease

Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies

Characterizing brain structures and remodeling after TBI based on information content, diffusion entropy

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

Comprehensive Characterization of Cancer Driver Genes and Mutations

Cortical ependymoma. A case report and review

Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells

Differential expression of aurora-A kinase in T-cell lymphomas.

Dural marginal zone lymphoma with massive amyloid deposition: rare low-grade primary central nervous system B-cell lymphoma. Case report

EXTH-75. THE AURORA KINASE A INHIBITOR ALISERTIB IS SYNERGISTIC WITH IRINOTECAN AND CARBOPLATIN AGAINST GLIOBLASTOMA CELLS

Early neonatal diagnosis of long-chain 3-hydroxyacyl coenzyme a dehydrogenase and mitochondrial trifunctional protein deficiencies.

Emi1 protein accumulation implicates misregulation of the anaphase promoting complex/cyclosome pathway in ovarian clear cell carcinoma

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis

Glioblastoma cell enrichment is critical for analysis of phosphorylated drug targets and proteomic-genomic correlations

Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo

Gliosarcoma with melanocytic differentiation

Histologic findings of disc, end plate and neural elements after coblation of nucleus pulposus: an experimental nucleoplasty study.

Histological predictors of outcome in ependymoma are dependent on anatomic site within the central nervous system

Holoprosencephaly associated with an apparent isolated 2q37.1-->2q37.3 deletion

Intramedullary papillary ependymoma with choroid plexus differentiation and cerebrospinal fluid dissemination to the brain

Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence.

Malignant PEComa of the skull base

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

Morphological and molecular features of astroblastoma, including BRAFV600E mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults

NHERF1/EBP50 and NF2 as diagnostic markers for choroid plexus tumors

Non-lysosomal cycling pathway for atrial natriuretic peptide activated by protein kinase C in human NPE cells

Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors.

Overview of Molecular Signal Transduction of Malignant Gliomas and Correlation with Responses to Targeted Therapy Recent advances in Molecular Characterization of Glioblastoma

Overview of Molecular Signal Transduction of Malignant Gliomas and Correlation with Responses to Targeted Therapy Recent advances in Molecular Characterization of Glioblastoma

PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance

Patterns of brain infiltration and secondary structure formation in supratentorial ependymal tumors

Pituitary carcinomas: review of the current literature and report of atypical case

Predicting survival in glioblastomas using diffusion tensor imaging metrics.

Primary Meningeal Pleomorphic Xanthoastrocytoma With Anaplastic Features: A Report of 2 Cases, One With BRAF(V600E) Mutation and Clinical Response to the BRAF Inhibitor Dabrafenib

Primary paraspinal leiomyosarcoma invading the cervical spinal canal successfully treated with surgery, radiotherapy, and chemotherapy. Case report

Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair

RARE-18EXCEPTIONAL RESPONDERS: A PERSONALIZED APPROACH TO TARGETED TREATMENT OF UNCOMMON BRAIN TUMORS.

Radiation necrosis mimicking rapid intracranial progression of melanoma metastasis in two patients treated with vemurafenib.

Screening of tissue microarrays for ubiquitin proteasome system components in tumors

Splenic infarction evidenced by whole-body Tc-99m HMPAO-labeled leukocyte scan

Synchronous subarachnoid drop metastases from a pituitary adenoma with multiple recurrences ⬇️

The CNS penetrating taxane TPI 287 and the AURKA inhibitor alisertib induce synergistic apoptosis in glioblastoma cells

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation

The ubiquitin proteasome system in neuropathology

Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class