Lista de obras - Matthew J Fuchter - Dominio Público Uruguay

500-fold amplification of small molecule circularly polarized luminescence through circularly polarized FRET

artículo científico publicado en 2020

500‐Fold Amplification of Small Molecule Circularly Polarised Luminescence through Circularly Polarised FRET

artículo científico publicado en 2020

A combinatorial approach to improving the performance of azoarene photoswitches

artículo científico publicado en 2019

A computational exploration of the crystal energy and charge-carrier mobility landscapes of the chiral [6]helicene molecule

artículo científico publicado en 2018

A high throughput screen for next-generation leads targeting malaria parasite transmission

artículo científico publicado en 2018

A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration

artículo científico publicado en 2010

A scalable and expedient route to 1-aza[6]helicene derivatives and its subsequent application to a chiral-relay asymmetric strategy

artículo científico publicado en 2013

A ‘push–pull’ tropylium-fused aminoporphyrazine

An unusual oxidative rearrangement of [7]-helicene

Arylazopyrazoles for Long-Term Thermal Energy Storage and Optically-Triggered Heat Release below 0 °C

artículo científico publicado en 2020

Arylazopyrazoles: Azoheteroarene Photoswitches Offering Quantitative Isomerization and Long Thermal Half-Lives

artículo científico publicado en 2014

Best practices in the measurement of circularly polarised photodetectors

Calcium-mediated stereoselective reduction of α,β-epoxy ketones

Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases ⬇️

artículo científico publicado el 1 de marzo de 2013

Chemical Z − E Isomer Switching of Arylazopyrazoles Using Acid

artículo científico publicado en 2019

Chiroptical studies on brevianamide B: vibrational and electronic circular dichroism confronted

artículo científico publicado en 2015

Circularly Polarized Phosphorescent Electroluminescence with a High Dissymmetry Factor from PHOLEDs Based on a Platinahelicene

artículo científico publicado en 2016

Circularly polarized light detection by a chiral organic semiconductor transistor

article

Clean and efficient synthesis of O-silylcarbamates and ureas in supercritical carbon dioxide

artículo científico publicado en 2008

Computational Screening of Organic Semiconductors: Exploring Side-Group Functionalisation and Assembly to Optimise Charge Transport in Chiral Molecules

artículo científico publicado en 2020

Computational Screening of Organic Semiconductors: Exploring Side-Group Functionalisation and Assembly to Optimise Charge Transport in Chiral Molecules

artículo científico publicado en 2020

Correction to "Arylazopyrazoles: Azoheteroarene Photoswitches Offering Quantitative Isomerization and Long Thermal Half-Lives

artículo científico publicado en 2016

Correction to Emergent Properties of an Organic Semiconductor Driven by its Molecular Chirality

artículo científico publicado en 2018

Correction: A computational exploration of the crystal energy and charge-carrier mobility landscapes of the chiral [6]helicene molecule

artículo científico publicado en 2018

Corrigendum: Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study

artículo científico publicado en 2018

Current limitations and future opportunities for epigenetic therapies.

artículo científico publicado en 2012

Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets

artículo científico publicado en 2012

Designing effective 'frustrated Lewis pair' hydrogenation catalysts

artículo científico publicado en 2017

Development of a Photo-Cross-Linkable Diaminoquinazoline Inhibitor for Target Identification in Plasmodium falciparum.

artículo científico publicado en 2018

Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance

artículo científico publicado en 2013

Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compounds

artículo científico publicado en 2014

Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes

artículo científico publicado en 2008

Direct NHC-catalysed redox amidation using CO2 for traceless masking of amine nucleophiles.

artículo científico publicado en 2016

Direct Reductive Amination of Carbonyl Compounds Catalyzed by a Moisture Tolerant Tin(IV) Lewis Acid.

artículo científico publicado en 2018

Disequilibrating azobenzenes by visible-light sensitization under confinement

artículo científico publicado en 2023

Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells

artículo científico publicado en 2015

Dual wavelength asymmetric photochemical synthesis with circularly polarized light

artículo científico publicado en 2015

Editorial

Effective macrophage delivery using RAFT copolymer derived nanoparticles

Emergent Properties of an Organic Semiconductor Driven by its Molecular Chirality.

artículo científico publicado en 2017

Enantioselective reduction of N-alkyl ketimines with frustrated Lewis pair catalysis using chiral borenium ions

scientific article published on 01 June 2019

Facile Protocol for Water-Tolerant "Frustrated Lewis Pair"-Catalyzed Hydrogenation

artículo científico publicado en 2015

Fullerene Desymmetrization as a Means to Achieve Single-Enantiomer Electron Acceptors with Maximized Chiroptical Responsiveness

artículo científico publicado en 2020

Fullerene Dissymmetrization as a Means to Achieve Single Enantiomer Electron Acceptors with Maximized Chiroptical Responsiveness

artículo científico publicado en 2020

Fullerene Dissymmetrization as a Means to Achieve Single Enantiomer Electron Acceptors with Maximized Chiroptical Responsiveness

artículo científico publicado en 2020

Glycosylated Nanoparticles Derived from RAFT Polymerization for Effective Drug Delivery to Macrophages

artículo científico publicado en 2020

Gold(I) mediated rearrangement of [7]-helicene to give a benzo[cd]pyrenium cation embedded in a chiral framework.

artículo científico publicado en 2013

Highly efficient inverted circularly polarized organic light emitting diodes

scientific article published on 05 August 2020

Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A.

artículo científico publicado en 2012

Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity

artículo científico publicado en 2017

Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity† †The authors declare no competing interests. ‡ ‡Electronic supplementary information (ESI) available: Supple

artículo científico publicado en 2017

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

artículo científico publicado en 2014

ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment.

artículo científico publicado en 2018

Identification of 2,4-diamino-6,7-dimethoxyquinoline derivatives as G9a inhibitors†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4md00274a.

artículo científico publicado en 2014

In memoriam Alasdair James Campbell (11 May 1961–27 February 2021)

artículo científico publicado en 2021

Induction of circularly polarized electroluminescence from an achiral light-emitting polymer via a chiral small-molecule dopant

artículo científico publicado en 2013

Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.

artículo científico publicado en 2017

Intense redox-driven chiroptical switching with a 580 mV hysteresis actuated through reversible dimerization of an azoniahelicene

artículo científico publicado en 2017

Inverting the Handedness of Circularly Polarized Luminescence from Light-Emitting Polymers Using Film Thickness

scientific article published on 26 June 2019

Kinetic method for the large-scale analysis of the binding mechanism of histone deacetylase inhibitors

artículo científico publicado en 2014

Lanthanide replacement in organic synthesis: Luche-type reduction of α,β-unsaturated ketones in the presence of calcium triflate

Mechanistic and chiroptical studies on the desulfurization of epidithiodioxopiperazines reveal universal retention of configuration at the bridgehead carbon atoms

artículo científico publicado en 2013

Metal-free hydrogenation catalyzed by an air-stable borane: use of solvent as a frustrated Lewis base

artículo científico publicado en 2014

Multigram Synthesis of a Water-Soluble Porphyrazine and Derivedseco-Porphyrazine Labeling Agents

artículo científico publicado en 2007

Natural optical activity as the origin of the large chiroptical properties in π-conjugated polymer thin films

artículo científico publicado en 2020

New synthetic strategies towards psammaplin A, access to natural product analogues for biological evaluation

artículo científico publicado en 2010

Nonmetal Catalyzed Hydrogenation of Carbonyl Compounds

artículo científico publicado en 2014

N‐Heterocyclic Carbene Mediated Activation of Tetravalent Silicon Compounds: A Critical Evaluation ⬇️

artículo científico publicado el 2 de noviembre de 2010

On the Determination of the Stereochemistry of Semisynthetic Natural Product Analogues using Chiroptical Spectroscopy: Desulfurization of Epidithiodioxopiperazine Fungal Metabolites

artículo científico publicado en 2011

On the function of the internal cavity of histone deacetylase protein 8: R37 is a crucial residue for catalysis

artículo científico publicado en 2011

On the histone lysine methyltransferase activity of fungal metabolite chaetocin.

artículo científico publicado en 2013

On the promise of photopharmacology using photoswitches: a medicinal chemist's perspective

artículo científico publicado en 2020

One-Pot Formation of Allylic Chlorides from Carbonyl Derivatives

scientific article published on 04 October 2008

Paper No 2.2: Circularly Polarised Organic Light-Emitting Diodes Using Conventional Light-Emitting Polymers and a Chiral Small-Molecule Dopant

article

Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

artículo científico publicado en 2014

Perspectives on natural product epigenetic modulators in chemical biology and medicine.

artículo científico publicado en 2013

Photoswitchable basicity through the use of azoheteroarenes

artículo científico publicado en 2016

Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites

artículo científico publicado en 2016

Porphyrazines as Molecular Scaffolds: Flexible Syntheses of Novel Multimetallic Complexes

artículo científico publicado en 2006

Porphyrazines: Designer Macrocycles by Peripheral Substituent Change

ROM polymerization-capture-release strategy for the chromatography-free synthesis of novel unsymmetrical porphyrazines

artículo científico publicado en 2005

ROM polymerization-capture-release: application to the synthesis of unsymmetrical porphyrazinedithiols and peripherally metalated derivatives

artículo científico publicado en 2005

Regiochemical observations on the lithiation of 1,2,4-trichlorobenzene and reaction with DMF and oxamide electrophiles in THF

Ring-opening metathesis polymer sphere-supported seco-porphyrazines: efficient and recyclable photooxygenation catalysts

artículo científico publicado en 2006

SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2.

artículo científico publicado en 2010

Serendipitous synthesis of trimetallic porphyrazine triads

Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum

artículo científico publicado en 2012

Stoichiometric C-H arylation of tricarbonyl(arene)chromium complexes bearing pyridine directing groups

artículo científico publicado en 2013

Structure-Activity Relationship Studies of a Novel Class of Transmission Blocking Antimalarials Targeting Male Gametes

artículo científico publicado en 2019

Synthesis of porphyrazine-octaamine, hexamine and diamine derivatives

Synthesis of sterically encumbered C10-arylated benzo[h]quinolines using ortho-substituted aryl boronic acids

artículo científico publicado en 2013

Synthetic studies on the reverse antibiotic natural products, the nybomycins

artículo científico publicado en 2019

TRPswitch - a step function chemo-optogenetic ligand for the vertebrate TRPA1 channel

scientific article published on 23 September 2020

The Discovery of Novel 10,11-Dihydro-5H-dibenz[b,f]azepine SIRT2 Inhibitors.

artículo científico publicado en 2012

The Influence of Nitrogen Position on Charge Carrier Mobility in Enantiopure Aza[6]helicene Crystals

The added value of small-molecule chirality in technological applications

The antimalarial screening landscape-looking beyond the asexual blood stage

scientific article published on 12 March 2019

The design and synthesis of novel IBiox N-heterocyclic carbeneligands derived from substituted amino-indanols

scientific article published on 28 November 2011

The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity

artículo científico publicado en 2009

The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model.

artículo científico publicado en 2014

The influence of nitrogen position on charge carrier mobility in enantiopure aza[6]helicene crystals

artículo científico publicado en 2019

The transcriptional repressor REV-ERB as a novel target for disease

artículo científico publicado en 2020

Thermodynamics of ligand binding to histone deacetylase like amidohydrolase from Bordetella/Alcaligenes

artículo científico publicado en 2014

Thienopyrimidinone Based Sirtuin-2 (SIRT2)-Selective Inhibitors Bind in the Ligand Induced Selectivity Pocket.

artículo científico publicado en 2017

Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors

artículo científico publicado en 2013

Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors.

artículo científico publicado en 2016

Tuning Azoheteroarene Photoswitch Performance through Heteroaryl Design

artículo científico publicado en 2016

Unbiased Mass Spectrometry Elucidation of the Targets and Mechanisms of Activity-Based Probes: A Case Study Involving Sulfonyl Fluorides

artículo científico publicado en 2018

Versatile Catalytic Hydrogenation Using A Simple Tin(IV) Lewis Acid

artículo científico publicado en 2016

Versatile Catalytic Hydrogenation Using A Simple Tin(IV) Lewis Acid

[7]-Helicene: a chiral molecular tweezer for silver(i) salts

artículo científico publicado en 2012

Lista de obras de Matthew J Fuchter

500-fold amplification of small molecule circularly polarized luminescence through circularly polarized FRET

500‐Fold Amplification of Small Molecule Circularly Polarised Luminescence through Circularly Polarised FRET

A combinatorial approach to improving the performance of azoarene photoswitches

A computational exploration of the crystal energy and charge-carrier mobility landscapes of the chiral [6]helicene molecule

A high throughput screen for next-generation leads targeting malaria parasite transmission

A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration

A scalable and expedient route to 1-aza[6]helicene derivatives and its subsequent application to a chiral-relay asymmetric strategy

A ‘push–pull’ tropylium-fused aminoporphyrazine

An unusual oxidative rearrangement of [7]-helicene

Arylazopyrazoles for Long-Term Thermal Energy Storage and Optically-Triggered Heat Release below 0 °C

Arylazopyrazoles: Azoheteroarene Photoswitches Offering Quantitative Isomerization and Long Thermal Half-Lives

Best practices in the measurement of circularly polarised photodetectors

Calcium-mediated stereoselective reduction of α,β-epoxy ketones

Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases ⬇️

Chemical Z − E Isomer Switching of Arylazopyrazoles Using Acid

Chiroptical studies on brevianamide B: vibrational and electronic circular dichroism confronted

Circularly Polarized Phosphorescent Electroluminescence with a High Dissymmetry Factor from PHOLEDs Based on a Platinahelicene

Circularly polarized light detection by a chiral organic semiconductor transistor

Clean and efficient synthesis of O-silylcarbamates and ureas in supercritical carbon dioxide

Computational Screening of Organic Semiconductors: Exploring Side-Group Functionalisation and Assembly to Optimise Charge Transport in Chiral Molecules

Computational Screening of Organic Semiconductors: Exploring Side-Group Functionalisation and Assembly to Optimise Charge Transport in Chiral Molecules

Correction to "Arylazopyrazoles: Azoheteroarene Photoswitches Offering Quantitative Isomerization and Long Thermal Half-Lives

Correction to Emergent Properties of an Organic Semiconductor Driven by its Molecular Chirality

Correction: A computational exploration of the crystal energy and charge-carrier mobility landscapes of the chiral [6]helicene molecule

Corrigendum: Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study

Current limitations and future opportunities for epigenetic therapies.

Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets

Designing effective 'frustrated Lewis pair' hydrogenation catalysts

Development of a Photo-Cross-Linkable Diaminoquinazoline Inhibitor for Target Identification in Plasmodium falciparum.

Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance

Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compounds

Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes

Direct NHC-catalysed redox amidation using CO2 for traceless masking of amine nucleophiles.

Direct Reductive Amination of Carbonyl Compounds Catalyzed by a Moisture Tolerant Tin(IV) Lewis Acid.

Disequilibrating azobenzenes by visible-light sensitization under confinement

Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells

Dual wavelength asymmetric photochemical synthesis with circularly polarized light

Editorial

Effective macrophage delivery using RAFT copolymer derived nanoparticles

Emergent Properties of an Organic Semiconductor Driven by its Molecular Chirality.

Enantioselective reduction of N-alkyl ketimines with frustrated Lewis pair catalysis using chiral borenium ions

Facile Protocol for Water-Tolerant "Frustrated Lewis Pair"-Catalyzed Hydrogenation

Fullerene Desymmetrization as a Means to Achieve Single-Enantiomer Electron Acceptors with Maximized Chiroptical Responsiveness

Fullerene Dissymmetrization as a Means to Achieve Single Enantiomer Electron Acceptors with Maximized Chiroptical Responsiveness

Fullerene Dissymmetrization as a Means to Achieve Single Enantiomer Electron Acceptors with Maximized Chiroptical Responsiveness

Glycosylated Nanoparticles Derived from RAFT Polymerization for Effective Drug Delivery to Macrophages

Gold(I) mediated rearrangement of [7]-helicene to give a benzo[cd]pyrenium cation embedded in a chiral framework.

Highly efficient inverted circularly polarized organic light emitting diodes

Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A.

Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity

Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity† †The authors declare no competing interests. ‡ ‡Electronic supplementary information (ESI) available: Supple

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment.

Identification of 2,4-diamino-6,7-dimethoxyquinoline derivatives as G9a inhibitors†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4md00274a.

In memoriam Alasdair James Campbell (11 May 1961–27 February 2021)

Induction of circularly polarized electroluminescence from an achiral light-emitting polymer via a chiral small-molecule dopant

Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.

Intense redox-driven chiroptical switching with a 580 mV hysteresis actuated through reversible dimerization of an azoniahelicene

Inverting the Handedness of Circularly Polarized Luminescence from Light-Emitting Polymers Using Film Thickness

Kinetic method for the large-scale analysis of the binding mechanism of histone deacetylase inhibitors

Lanthanide replacement in organic synthesis: Luche-type reduction of α,β-unsaturated ketones in the presence of calcium triflate

Mechanistic and chiroptical studies on the desulfurization of epidithiodioxopiperazines reveal universal retention of configuration at the bridgehead carbon atoms

Metal-free hydrogenation catalyzed by an air-stable borane: use of solvent as a frustrated Lewis base

Multigram Synthesis of a Water-Soluble Porphyrazine and Derivedseco-Porphyrazine Labeling Agents

Natural optical activity as the origin of the large chiroptical properties in π-conjugated polymer thin films

New synthetic strategies towards psammaplin A, access to natural product analogues for biological evaluation

Nonmetal Catalyzed Hydrogenation of Carbonyl Compounds

N‐Heterocyclic Carbene Mediated Activation of Tetravalent Silicon Compounds: A Critical Evaluation ⬇️

On the Determination of the Stereochemistry of Semisynthetic Natural Product Analogues using Chiroptical Spectroscopy: Desulfurization of Epidithiodioxopiperazine Fungal Metabolites

On the function of the internal cavity of histone deacetylase protein 8: R37 is a crucial residue for catalysis

On the histone lysine methyltransferase activity of fungal metabolite chaetocin.

On the promise of photopharmacology using photoswitches: a medicinal chemist's perspective

One-Pot Formation of Allylic Chlorides from Carbonyl Derivatives

Paper No 2.2: Circularly Polarised Organic Light-Emitting Diodes Using Conventional Light-Emitting Polymers and a Chiral Small-Molecule Dopant

Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

Perspectives on natural product epigenetic modulators in chemical biology and medicine.

Photoswitchable basicity through the use of azoheteroarenes

Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites

Porphyrazines as Molecular Scaffolds: Flexible Syntheses of Novel Multimetallic Complexes