Lista de obras - Yves Collette - Dominio Público Uruguay

1H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein

artículo científico publicado en 2000

A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells

artículo científico publicado en 2015

A co-evolution perspective of the TNFSF and TNFRSF families in the immune system

artículo científico publicado en 2003

A robust and rapid xenograft model to assess efficacy of chemotherapeutic agents for human acute myeloid leukemia.

artículo científico publicado en 2015

A role for the neuronal protein collapsin response mediator protein 2 in T lymphocyte polarization and migration.

artículo científico publicado en 2005

A simplified, 96-well-adapted, ATP luminescence-based motility assay

artículo científico publicado en 2009

A specific protein disorder catalyzer of HIV-1 Nef

article

Active Transcription of the HumanFASL/CD95L/TNFSF6Promoter Region in T Lymphocytes Involves Chromatin Remodeling

scientific article published in Journal of Biological Chemistry

Altered splicing in hematological malignancies reveals a tissue-specific translational block of the Src-family tyrosine kinase fyn brain isoform expression

artículo científico publicado en 2004

Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn.

artículo científico publicado en 2009

Amine-guanidine switch: a promising approach to improve DNA binding and antiproliferative activities

artículo científico publicado en 2007

An improved synthesis of an umbelliferyl 5-thioxylopyranoside, precursor of the antithrombotic drug Iliparcil

scientific article published on 01 May 1999

Anti-leukemia activity of MS-275 histone deacetylase inhibitor implicates 4-1BBL/4-1BB immunomodulatory functions

artículo científico publicado en 2009

Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1.

artículo científico publicado en 2011

BTN3A molecules considerably improve Vγ9Vδ2T cells-based immunotherapy in acute myeloid leukemia

artículo científico publicado en 2016

CD28 can promote T cell survival through a phosphatidylinositol 3-kinase-independent mechanism

scholarly article by Yves Collette et al published December 1997 in European Journal of Immunology

CD95L cell surface cleavage triggers a prometastatic signaling pathway in triple-negative breast cancer

artículo científico publicado en 2013

Cancer et agents pathogènes

artículo científico publicado en 2008

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

artículo científico publicado en 2017

Context-selective death of acute myeloid leukemia cells triggered by the novel hybrid retinoid-HDAC inhibitor MC2392.

artículo científico publicado en 2014

Coxiella burnetii avoids macrophage phagocytosis by interfering with spatial distribution of complement receptor 3.

artículo científico publicado en 2003

Cutting edge: recruitment of the ancestral fyn gene during emergence of the adaptive immune system

artículo científico publicado en 2002

Design of N-substituted amino caproic hydroxamic acid histone deacetylase inhibitors reveal an essential role for cap atomic composition

artículo científico publicado en 2012

Distinct regulation of T-cell death by CD28 depending on both its aggregation and T-cell receptor triggering: a role for Fas-FasL.

artículo científico publicado en 1998

Drug response profiling can predict response to ponatinib in a patient with t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia

artículo científico publicado en 2015

Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment

artículo científico publicado en 2004

Evidence for intact CD28 signaling in T cell hyporesponsiveness induced by the HIV-1nef gene

article

Evidences for ubiquitination and intracellular trafficking of LAT, the linker of activated T cells

article

Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins

artículo científico publicado en 2016

Frontline: Characterization of BT3 molecules belonging to the B7 family expressed on immune cells

scientific journal article

Full peptide synthesis, purification, and characterization of six Tat variants. Differences observed between HIV-1 isolates from Africa and other continents

artículo científico publicado en 1999

Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase

artículo científico publicado en 2004

Histone méthyltransférases

article from 2011

Human Vγ9Vδ2 T cells specifically recognize and kill acute myeloid leukemic blasts

artículo científico publicado en 2012

Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway.

artículo científico publicado en 1999

Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X

artículo científico publicado en 2010

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer

artículo científico publicado en 2016

Immunomodulatory Drugs Exert Anti-Leukemia Effects in Acute Myeloid Leukemia by Direct and Immunostimulatory Activities.

artículo científico publicado en 2018

Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach

artículo científico publicado en 2018

Interaction with simian Hck tyrosine kinase reveals convergent evolution of the Nef protein from simian and human immunodeficiency viruses despite differential molecular surface usage

artículo científico publicado en 2002

JAM-C Identifies Src Family Kinase-Activated Leukemia-Initiating Cells and Predicts Poor Prognosis in Acute Myeloid Leukemia.

artículo científico publicado en 2017

Mechanisms regulating expression of the tumor necrosis factor-related light gene. Role of calcium-signaling pathway in the transcriptional control

artículo científico publicado en 2002

Modified cap group suberoylanilide hydroxamic acid histone deacetylase inhibitor derivatives reveal improved selective antileukemic activity.

artículo científico publicado en 2010

Nectin-4: a new prognostic biomarker for efficient therapeutic targeting of primary and metastatic triple-negative breast cancer

artículo científico publicado en 2016

Non-receptor protein tyrosine kinases as immune targets of viruses

artículo científico publicado en 1997

Parameters involved in the recognition of fresh human leukemic blasts by tumor-specific cytolytic T cell clones: a model study

artículo científico publicado en 2000

Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects.

artículo científico publicado en 1996

Potentiation of Tumor Necrosis Factor-Induced NF-κB Activation by Deacetylase Inhibitors Is Associated with a Delayed Cytoplasmic Reappearance of IκBα.

artículo científico publicado en 2004

Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha

artículo científico publicado en 2003

Primary B-CLL resistance to NK cell cytotoxicity can be overcome in vitro and in vivo by priming NK cells and monoclonal antibody therapy

artículo científico publicado en 2012

Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy

artículo científico publicado en 2016

Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein

artículo científico publicado en 2007

Protein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery

artículo científico publicado en 2016

Role of ICAM-3 in the initial interaction of T lymphocytes and APCs

article published in 2002

Role of Tec kinase in nuclear factor of activated T cells signaling

artículo científico publicado en 2000

Signaling-dependent immobilization of acylated proteins in the inner monolayer of the plasma membrane

artículo científico publicado en 2006

Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation

artículo científico publicado en 1999

Similarity between Nef of primate lentiviruses and p15E of murine and feline leukaemia viruses.

artículo científico publicado en 1996

Specific Th1 cytokine down-regulation associated with primary clinically derived human immunodeficiency virus type 1 Nef gene-induced expression.

artículo científico publicado en 1996

Stereoselective ring contraction of 2,5-diketopiperazines: An innovative approach to the synthesis of promising bioactive 5-membered scaffolds

article published in 2010

Stereoselective synthesis of original spirolactams displaying promising folded structures.

artículo científico publicado en 2013

Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)

artículo científico publicado en 2012

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

artículo científico publicado en 2009

Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies

artículo científico publicado en 2002

Synergy and allostery in ligand binding by HIV-1 Nef

artículo científico publicado en 2021

Tec kinases: a family with multiple roles in immunity

artículo científico publicado en 2000

The Primate Lentivirus-Encoded Nef Protein Can Regulate Several Steps of the Viral Replication Cycle

The distinct capacity of Fyn and Lck to phosphorylate Sam68 in T cells is essentially governed by SH3/SH2-catalytic domain linker interactions

artículo científico publicado en 2002

The histone deacetylase inhibitor abexinostat induces cancer stem cells differentiation in breast cancer with low Xist expression

artículo científico publicado en 2013

The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.

artículo científico publicado en 1998

The role of HIV1 Nef in T-cell activation: Nef impairs induction of Th1 cytokines and interacts with the Src family tyrosine kinase Lck.

artículo científico publicado en 1997

The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras

artículo científico publicado en 1994

The tyrosine kinase Hck is an inhibitor of HIV-1 replication counteracted by the viral vif protein

artículo científico publicado en 2001

Therapeutic targeting of c-Myc in T-cell acute lymphoblastic leukemia, T-ALL

artículo científico publicado en 2014

Towards a consensus for a role of Nef in both viral replication and immunomodulation?

artículo científico publicado en 1997

Transcription factor binding sites in the pol gene intragenic regulatory region of HIV-1 are important for virus infectivity

artículo científico publicado en 2005

Tumor selective cytotoxic action of a thiomorpholin hydroxamate inhibitor (TMI-1) in breast cancer

artículo científico publicado en 2012

Lista de obras de Yves Collette

1H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein

A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells

A co-evolution perspective of the TNFSF and TNFRSF families in the immune system

A robust and rapid xenograft model to assess efficacy of chemotherapeutic agents for human acute myeloid leukemia.

A role for the neuronal protein collapsin response mediator protein 2 in T lymphocyte polarization and migration.

A simplified, 96-well-adapted, ATP luminescence-based motility assay

A specific protein disorder catalyzer of HIV-1 Nef

Active Transcription of the HumanFASL/CD95L/TNFSF6Promoter Region in T Lymphocytes Involves Chromatin Remodeling

Altered splicing in hematological malignancies reveals a tissue-specific translational block of the Src-family tyrosine kinase fyn brain isoform expression

Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn.

Amine-guanidine switch: a promising approach to improve DNA binding and antiproliferative activities

An improved synthesis of an umbelliferyl 5-thioxylopyranoside, precursor of the antithrombotic drug Iliparcil

Anti-leukemia activity of MS-275 histone deacetylase inhibitor implicates 4-1BBL/4-1BB immunomodulatory functions

Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1.

BTN3A molecules considerably improve Vγ9Vδ2T cells-based immunotherapy in acute myeloid leukemia

CD28 can promote T cell survival through a phosphatidylinositol 3-kinase-independent mechanism

CD95L cell surface cleavage triggers a prometastatic signaling pathway in triple-negative breast cancer

Cancer et agents pathogènes

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Context-selective death of acute myeloid leukemia cells triggered by the novel hybrid retinoid-HDAC inhibitor MC2392.

Coxiella burnetii avoids macrophage phagocytosis by interfering with spatial distribution of complement receptor 3.

Cutting edge: recruitment of the ancestral fyn gene during emergence of the adaptive immune system

Design of N-substituted amino caproic hydroxamic acid histone deacetylase inhibitors reveal an essential role for cap atomic composition

Distinct regulation of T-cell death by CD28 depending on both its aggregation and T-cell receptor triggering: a role for Fas-FasL.

Drug response profiling can predict response to ponatinib in a patient with t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia

Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment

Evidence for intact CD28 signaling in T cell hyporesponsiveness induced by the HIV-1nef gene

Evidences for ubiquitination and intracellular trafficking of LAT, the linker of activated T cells

Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins

Frontline: Characterization of BT3 molecules belonging to the B7 family expressed on immune cells

Full peptide synthesis, purification, and characterization of six Tat variants. Differences observed between HIV-1 isolates from Africa and other continents

Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase

Histone méthyltransférases

Human Vγ9Vδ2 T cells specifically recognize and kill acute myeloid leukemic blasts

Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway.

Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer

Immunomodulatory Drugs Exert Anti-Leukemia Effects in Acute Myeloid Leukemia by Direct and Immunostimulatory Activities.

Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach

Interaction with simian Hck tyrosine kinase reveals convergent evolution of the Nef protein from simian and human immunodeficiency viruses despite differential molecular surface usage

JAM-C Identifies Src Family Kinase-Activated Leukemia-Initiating Cells and Predicts Poor Prognosis in Acute Myeloid Leukemia.

Mechanisms regulating expression of the tumor necrosis factor-related light gene. Role of calcium-signaling pathway in the transcriptional control

Modified cap group suberoylanilide hydroxamic acid histone deacetylase inhibitor derivatives reveal improved selective antileukemic activity.

Nectin-4: a new prognostic biomarker for efficient therapeutic targeting of primary and metastatic triple-negative breast cancer

Non-receptor protein tyrosine kinases as immune targets of viruses

Parameters involved in the recognition of fresh human leukemic blasts by tumor-specific cytolytic T cell clones: a model study

Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects.

Potentiation of Tumor Necrosis Factor-Induced NF-κB Activation by Deacetylase Inhibitors Is Associated with a Delayed Cytoplasmic Reappearance of IκBα.

Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha

Primary B-CLL resistance to NK cell cytotoxicity can be overcome in vitro and in vivo by priming NK cells and monoclonal antibody therapy

Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy

Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein

Protein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery

Role of ICAM-3 in the initial interaction of T lymphocytes and APCs

Role of Tec kinase in nuclear factor of activated T cells signaling

Signaling-dependent immobilization of acylated proteins in the inner monolayer of the plasma membrane

Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation

Similarity between Nef of primate lentiviruses and p15E of murine and feline leukaemia viruses.

Specific Th1 cytokine down-regulation associated with primary clinically derived human immunodeficiency virus type 1 Nef gene-induced expression.

Stereoselective ring contraction of 2,5-diketopiperazines: An innovative approach to the synthesis of promising bioactive 5-membered scaffolds

Stereoselective synthesis of original spirolactams displaying promising folded structures.

Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies

Synergy and allostery in ligand binding by HIV-1 Nef

Tec kinases: a family with multiple roles in immunity

The Primate Lentivirus-Encoded Nef Protein Can Regulate Several Steps of the Viral Replication Cycle

The distinct capacity of Fyn and Lck to phosphorylate Sam68 in T cells is essentially governed by SH3/SH2-catalytic domain linker interactions

The histone deacetylase inhibitor abexinostat induces cancer stem cells differentiation in breast cancer with low Xist expression

The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.

The role of HIV1 Nef in T-cell activation: Nef impairs induction of Th1 cytokines and interacts with the Src family tyrosine kinase Lck.

The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras

The tyrosine kinase Hck is an inhibitor of HIV-1 replication counteracted by the viral vif protein

Therapeutic targeting of c-Myc in T-cell acute lymphoblastic leukemia, T-ALL

Towards a consensus for a role of Nef in both viral replication and immunomodulation?

Transcription factor binding sites in the pol gene intragenic regulatory region of HIV-1 are important for virus infectivity

Tumor selective cytotoxic action of a thiomorpholin hydroxamate inhibitor (TMI-1) in breast cancer