Filtros de búsqueda

Lista de obras de Norma C. Gutiérrez

6q deletion in Waldenström macroglobulinemia is associated with features of adverse prognosis

scientific article published on 01 January 2007

A New Next-Generation Sequencing Strategy for the Simultaneous Analysis of Mutations and Chromosomal Rearrangements at DNA Level in Acute Myeloid Leukemia Patients

artículo científico publicado en 2019

A Next-Generation Sequencing Strategy for Evaluating the Most Common Genetic Abnormalities in Multiple Myeloma.

artículo científico publicado en 2016

A high number of losses in 13q14 chromosome band is associated with a worse outcome and biological differences in patients with B-cell chronic lymphoid leukemia.

artículo científico publicado en 2009

A multiparameter flow cytometry immunophenotypic algorithm for the identification of newly diagnosed symptomatic myeloma with an MGUS-like signature and long-term disease control

artículo científico publicado en 2013

A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors

artículo científico publicado en 2012

Abnormalities on 1q and 7q are associated with poor outcome in sporadic Burkitt's lymphoma. A cytogenetic and comparative genomic hybridization study

artículo científico publicado en 2003

Amiloride, An Old Diuretic Drug, Is a Potential Therapeutic Agent for Multiple Myeloma.

artículo científico publicado en 2017

Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry.

artículo científico publicado en 2012

Analytical and clinical validation of a novel in-house deep-sequencing method for minimal residual disease monitoring in a phase II trial for multiple myeloma

artículo científico publicado en 2017

Array comparative genomic hybridization identifies genetic regions associated with outcome in aggressive diffuse large B-cell lymphomas.

artículo científico publicado en 2009

Autologous stem cell transplantation (ASCT) in patients with mantle cell lymphoma: a retrospective study of the Spanish lymphoma group (GELTAMO).

artículo científico publicado en 2017

BCR-ABL1-induced expression of HSPA8 promotes cell survival in chronic myeloid leukaemia

artículo científico publicado en 2008

Bence Jones proteinuria in smoldering multiple myeloma as a predictor marker of progression to symptomatic multiple myeloma.

artículo científico publicado en 2016

Bortezomib is an efficient agent in plasma cell leukemias

artículo científico publicado en 2005

Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: results of a multicenter phase 1/2 study

scientific article published on 13 June 2006

Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: updated time-to-events results and prognostic factors for time to progression

artículo científico publicado en 2008

Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple m

artículo científico publicado en 2010

CD117 expression in gammopathies is associated with an altered maturation of the myeloid and lymphoid hematopoietic cell compartments and favorable disease features

artículo científico publicado en 2010

CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype

artículo científico publicado en 2012

Chromosomal abnormalities are related to location and grade of osteoarthritis

scientific article published on 01 December 2004

Chromosomal imbalances identified by comparative genomic hybridization in sporadic parathyroid adenomas

artículo científico publicado en 2002

Clinical significance of CD81 expression by clonal plasma cells in high-risk smoldering and symptomatic multiple myeloma patients

artículo científico publicado en 2012

Combination of international scoring system 3, high lactate dehydrogenase, and t(4;14) and/or del(17p) identifies patients with multiple myeloma (MM) treated with front-line autologous stem-cell transplantation at high risk of early MM progression-r

artículo científico publicado en 2014

Combining fluorescent in situ hybridization data with ISS staging improves risk assessment in myeloma: an International Myeloma Working Group collaborative project

artículo científico publicado en 2012

Comparison of next-generation sequencing (NGS) and next-generation flow (NGF) for minimal residual disease (MRD) assessment in multiple myeloma

artículo científico publicado en 2020

Competition between clonal plasma cells and normal cells for potentially overlapping bone marrow niches is associated with a progressively altered cellular distribution in MGUS vs myeloma

article

Conventional diagnostics in multiple myeloma

artículo científico publicado en 2006

Correspondence

artículo científico publicado en 1998

Cytogenetic profiles in multiple myeloma and monoclonal gammopathy of undetermined significance: a study in highly purified aberrant plasma cells

artículo científico publicado en 2012

DEPTOR maintains plasma cell differentiation and favorably affects prognosis in multiple myeloma

artículo científico publicado en 2017

Depth of Response in Multiple Myeloma: A Pooled Analysis of Three PETHEMA/GEM Clinical Trials

artículo científico publicado en 2017

Deregulation of DNA double-strand break repair in multiple myeloma: implications for genome stability

artículo científico publicado en 2015

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling.

artículo científico publicado en 2010

Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution profile

artículo científico publicado en 2013

Differences in genetic changes between multiple myeloma and plasma cell leukemia demonstrated by comparative genomic hybridization

artículo científico publicado en 2001

Differentiation stage of myeloma plasma cells: biological and clinical significance.

artículo científico publicado en 2016

Early immunophenotypical evaluation of minimal residual disease in acute myeloid leukemia identifies different patient risk groups and may contribute to postinduction treatment stratification

scientific article published on 01 September 2001

Early myeloma-related death in elderly patients: development of a clinical prognostic score and evaluation of response sustainability role.

artículo científico publicado en 2018

Effects of IL-8 Up-Regulation on Cell Survival and Osteoclastogenesis in Multiple Myeloma

artículo científico publicado en 2016

Effects of imatinib mesylate on normal bone marrow cells from chronic myeloid leukemia patients in complete cytogenetic response.

artículo científico publicado en 2008

Evaluating gene expression profiling by quantitative polymerase chain reaction to develop a clinically feasible test for outcome prediction in multiple myeloma

artículo científico publicado en 2013

Expression of MLL-AF4 or AF4-MLL fusions does not impact the efficiency of DNA damage repair

artículo científico publicado en 2016

From Waldenström's macroglobulinemia to aggressive diffuse large B-cell lymphoma: a whole-exome analysis of abnormalities leading to transformation

artículo científico publicado en 2017

Gene expression profile reveals deregulation of genes with relevant functions in the different subclasses of acute myeloid leukemia.

artículo científico publicado en 2005

Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals

artículo científico publicado en 2007

Genetic Abnormalities and Patterns of Antigenic Expression in Multiple Myeloma

artículo científico publicado en 2005

Genetic heterogeneity of BCR/ABL+ adult B-cell precursor acute lymphoblastic leukemia: impact on the clinical, biological and immunophenotypical disease characteristics

artículo científico publicado en 2005

Genome-wide profiling of methylation identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes.

artículo científico publicado en 2012

Genomic analysis of a familial myelodysplasia/acute myeloid leukemia and inherited RUNX1 mutations without a pre-existing platelet disorder

artículo científico publicado en 2019

Genomic analysis of high-risk smoldering multiple myeloma.

artículo científico publicado en 2012

Geographic differences in the incidence of cytogenetic abnormalities of acute myelogenous leukemia (AML) in Spain

article

Hematological, immunophenotypic, and cytogenetic characteristics of acute myeloblastic leukemia with trisomy 11

artículo científico publicado en 2005

Heterogeneity of structural abnormalities in the 7q31.3∼q34 region in myeloid malignancies

artículo científico publicado en 2004

High-resolution copy number analysis of paired normal-tumor samples from diffuse large B cell lymphoma.

artículo científico publicado en 2015

High-risk cytogenetics and persistent minimal residual disease by multiparameter flow cytometry predict unsustained complete response after autologous stem cell transplantation in multiple myeloma

artículo científico publicado en 2011

IL-4 improves the detection of cytogenetic abnormalities in multiple myeloma and increases the proportion of clonally abnormal metaphases

artículo científico publicado en 1998

Identification of a novel recurrent gain on 20q13 in chronic lymphocytic leukemia by array CGH and gene expression profiling

article

Imatinib mesylate (STI571) inhibits multiple myeloma cell proliferation and potentiates the effect of common antimyeloma agents

artículo científico publicado en 2003

Imatinib mesylate elicits positive clinical response in atypical chronic myeloid leukemia involving the platelet-derived growth factor receptor beta

artículo científico publicado en 2003

Imatinib therapy of chronic myeloid leukemia restores the expression levels of key genes for DNA damage and cell-cycle progression

article

Immunophenotypic and Cytogenetic Comparison of Waldenström's Macroglobulinemia with Splenic Marginal Zone Lymphoma

artículo científico publicado en 2005

Impact of genetic abnormalities on survival after allogeneic hematopoietic stem cell transplantation in multiple myeloma.

artículo científico publicado en 2008

Improving overall survival and overcoming adverse prognosis in the treatment of cytogenetically high-risk multiple myeloma.

artículo científico publicado en 2012

In silico whole-genome screening for cancer-related single-nucleotide polymorphisms located in human mRNA untranslated regions

artículo científico publicado en 2007

In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by α4β1 cytoplasmic-binding proteins.

artículo científico publicado en 2015

In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone.

artículo científico publicado en 2014

Incidence and clinical characteristics of myeloproliferative neoplasms displaying a PDGFRB rearrangement.

artículo científico publicado en 2012

Incomplete DJH rearrangements of the IgH gene are frequent in multiple myeloma patients: immunobiological characteristics and clinical implications.

artículo científico publicado en 2003

Insights into epigenetic regulation of microRNA-155 expression in multiple myeloma

artículo científico publicado en 2015

Integration of global spectral karyotyping, CGH arrays, and expression arrays reveals important genes in the pathogenesis of glioblastoma multiforme

artículo científico publicado en 2012

Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse.

artículo científico publicado en 2016

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.

artículo científico publicado en 2009

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

scientific article published on 02 July 2013

Low expression of ZHX2, but not RCBTB2 or RAN, is associated with poor outcome in multiple myeloma.

artículo científico publicado en 2008

MYD88 L265P is a marker highly characteristic of, but not restricted to, Waldenström's macroglobulinemia.

artículo científico publicado en 2013

Maintenance therapy with bortezomib plus thalidomide or bortezomib plus prednisone in elderly multiple myeloma patients included in the GEM2005MAS65 trial

artículo científico publicado en 2012

Mesenchymal stem cells from multiple myeloma patients display distinct genomic profile as compared with those from normal donors

scientific article published on 09 April 2009

MicroRNA-223 is a novel negative regulator of HSP90B1 in CLL.

artículo científico publicado en 2015

Minimal residual disease in adolescent (older than 14 years) and adult acute lymphoblastic leukemias: early immunophenotypic evaluation has high clinical value.

artículo científico publicado en 2003

Minimal residual disease monitoring and immune profiling in multiple myeloma in elderly patients

artículo científico publicado en 2016

Mobilisation with G-CSF in healthy donors promotes a high but temporal deregulation of genes

article

Molecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple Myeloma

artículo científico publicado en 2016

Molecular biology of myeloma.

artículo científico publicado en 2007

Molecular characterization of the region 7q22.1 in splenic marginal zone lymphomas

artículo científico publicado en 2011

Molecular profiling of immunoglobulin heavy-chain gene rearrangements unveils new potential prognostic markers for multiple myeloma patients

artículo científico publicado en 2020

Monoclonal free light chains can be found in heavy chain diseases.

artículo científico publicado en 2010

Monocyte counts: an early index of haemopoietic reconstitution after peripheral blood stem cell transplantation

scientific article published on 01 December 2000

Multicolor fluorescence in situ hybridization studies in multiple myeloma and monoclonal gammopathy of undetermined significance.

artículo científico

Multifunctional role of Erk5 in multiple myeloma

artículo científico publicado en 2005

Multiparameter Flow Cytometry Evaluation of Plasma Cell DNA Content and Proliferation in 595 Transplant-Eligible Patients with Myeloma Included in the Spanish GEM2000 and GEM2005<65y Trials

article

Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation

artículo científico publicado en 2008

Multiple cranial neuropathy and intracranial hypertension associated with all-trans retinoic acid treatment in a young adult patient with acute promyelocytic leukemia

artículo científico publicado en 2012

Neurological complications after autologous stem cell transplantation

artículo científico publicado en 1999

Novel genomic imbalances in B-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics.

artículo científico publicado en 2001

Origin of Waldenstrom's macroglobulinaemia

artículo científico publicado en 2016

Outcome according to cytogenetic abnormalities and DNA ploidy in myeloma patients receiving short induction with weekly bortezomib followed by maintenance

artículo científico publicado en 2011

Overexpression of the VAV proto-oncogene product is associated with B-cell chronic lymphocytic leukaemia displaying loss on 13q.

artículo científico publicado en 2006

P53deletion may drive the clinical evolution and treatment response in multiple myeloma

artículo científico publicado en 2009

Patterns of BCR/ABL gene rearrangements by interphase fluorescence in situ hybridization (FISH) in BCR/ABL+ leukemias: incidence and underlying genetic abnormalities

article

Phase I/II study of weekly PM00104 (Zalypsis®) in patients with relapsed/refractory multiple myeloma.

artículo científico publicado en 2015

Phase II PETHEMA trial of alternating bortezomib and dexamethasone as induction regimen before autologous stem-cell transplantation in younger patients with multiple myeloma: efficacy and clinical implications of tumor response kinetics.

artículo científico publicado en 2007

Phenotypic identification of subclones in multiple myeloma with different chemoresistant, cytogenetic and clonogenic potential

artículo científico publicado en 2014

Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines

artículo científico publicado en 2014

Phenotypic, transcriptomic, and genomic features of clonal plasma cells in light-chain amyloidosis

artículo científico publicado en 2016

Post-transcriptional Modifications Contribute to the Upregulation of Cyclin D2 in Multiple Myeloma

artículo científico publicado en 2015

Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair

artículo científico publicado en 2017

Prognostic Value of Immunophenotyping in Multiple Myeloma: A Study by the PETHEMA/GEM Cooperative Study Groups on Patients Uniformly Treated With High-Dose Therapy

scientific article published on 28 April 2008

Prognostic and biologic significance of chromosomal imbalances assessed by comparative genomic hybridization in multiple myeloma

artículo científico publicado en 2004

Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated

artículo científico publicado en 2006

Prognostic utility of serum free light chain ratios and heavy-light chain ratios in multiple myeloma in three PETHEMA/GEM phase III clinical trials

artículo científico publicado en 2018

Quantitative PCR: an alternative approach to detect common copy number alterations in multiple myeloma

artículo científico publicado en 2017

Recovery of polyclonal immunoglobulins one year after autologous stem cell transplantation as a long-term predictor marker of progression and survival in multiple myeloma

artículo científico publicado en 2017

Reply to Brown et al: 'Correct application of variant classification guidelines in germline RUNX1 mutated disorders to assist clinical diagnosis'

artículo científico publicado en 2019

Reply to Wan et al

Report from the European Myeloma Network on interphase FISH in multiple myeloma and related disorders

artículo científico publicado en 2012

Response to imatinib mesylate in patients with hypereosinophilic syndrome.

artículo científico publicado en 2012

Restoration of microRNA-214 expression reduces growth of myeloma cells through positive regulation of P53 and inhibition of DNA replication

artículo científico publicado en 2012

Risk stratification in the era of novel therapies.

artículo científico publicado en 2009

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

artículo científico publicado en 2012

Sequential vs alternating administration of VMP and Rd in elderly patients with newly diagnosed MM

scientific article published on 23 October 2015

Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function

scientific article published on 01 January 2013

Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bortezomib and dexamethasone.

artículo científico publicado en 2016

Targeting Ongoing DNA Damage in Multiple Myeloma: Effects of DNA Damage Response Inhibitors on Plasma Cell Survival

artículo científico publicado en 2017

The Novel Pan-PIM Kinase Inhibitor, PIM447, Displays Dual Antimyeloma and Bone-Protective Effects, and Potently Synergizes with Current Standards of Care

artículo científico publicado en 2016

The Progression from MGUS to Smoldering Myeloma and Eventually to Multiple Myeloma Involves a Clonal Expansion of Genetically Abnormal Plasma Cells

artículo científico publicado en 2011

The cellular origin and malignant transformation of Waldenström macroglobulinemia.

artículo científico publicado en 2015

The combination of bortezomib and dexamethasone is an efficient therapy for relapsed/refractory scleromyxedema: a rare disease with new clinical insights

The cryptic IRF2BP2-RARA fusion transforms hematopoietic stem/progenitor cells and induces retinoid-sensitive acute promyelocytic leukemia

scientific article published on 22 November 2016

The histone deacetylase inhibitor LBH589 is a potent antimyeloma agent that overcomes drug resistance.

artículo científico publicado en 2006

The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma.

artículo científico publicado en 2017

The persistence of immunophenotypically normal residual bone marrow plasma cells at diagnosis identifies a good prognostic subgroup of symptomatic multiple myeloma patients

artículo científico publicado en 2009

The predominant myeloma clone at diagnosis, CDR3 defined, is constantly detectable across all stages of disease evolution.

artículo científico publicado en 2015

The prognostic value of multiparameter flow cytometry minimal residual disease assessment in relapsed multiple myeloma.

artículo científico publicado en 2014

Transcriptome analysis reveals molecular profiles associated with evolving steps of monoclonal gammopathies.

artículo científico publicado en 2014

Transcriptomic rationale for the synergy observed with dasatinib + bortezomib + dexamethasone in multiple myeloma

artículo científico publicado en 2011

Transient t(11;17)(q14;q12) in patient with chronic myelogenous leukemia in complete molecular response

artículo científico publicado en 2008

Unraveling the heterogeneity of IgM monoclonal gammopathies: a gene mutational and gene expression study.

artículo científico publicado en 2018

Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients

artículo científico publicado en 2010

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.

artículo científico publicado en 2015

Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response.

artículo científico publicado en 2011

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda