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Lista de obras de Patrick M. Dougherty

A cytokine-based neuroimmunologic mechanism of cancer-related symptoms

artículo científico publicado en 2004

A p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-alpha

artículo científico publicado en 2010

A population of cells in the human thalamic principal sensory nucleus respond to painful mechanical stimuli

artículo científico publicado en 1994

A quantitative sensory analysis of peripheral neuropathy in colorectal cancer and its exacerbation by oxaliplatin chemotherapy

artículo científico publicado en 2014

Acute inhibition of signalling phenotype of spinal GABAergic neurons by tumour necrosis factor-alpha

artículo científico publicado en 2011

Altered discharges of spinal neurons parallel the behavioral phenotype shown by rats with bortezomib related chemotherapy induced peripheral neuropathy

artículo científico publicado en 2014

Altered discharges of spinal wide dynamic range neurons and down-regulation of glutamate transporter expression in rats with paclitaxel-induced hyperalgesia

artículo científico publicado en 2005

An overview of animal models of pain: disease models and outcome measures

artículo científico publicado en 2013

Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symptoms

artículo científico publicado en 2003

Astrocytes, but not microglia, are activated in oxaliplatin and bortezomib-induced peripheral neuropathy in the rat

artículo científico publicado en 2014

Basic science and clinical management of painful and non-painful chemotherapy-related neuropathy

artículo científico publicado en 2015

Behavioral and electrophysiological studies in rats with cisplatin-induced chemoneuropathy

artículo científico publicado en 2008

Central sensitization and cutaneous hyperalgesia

Changes in lectin, GAP-43 and neuropeptide staining in the rat superficial dorsal horn following experimental peripheral neuropathy

artículo científico publicado en 1991

Changes in sensory processing in the spinal dorsal horn accompany vincristine-induced hyperalgesia and allodynia

artículo científico publicado en 2003

Characterization of baroreceptor-related neurons in the monkey insular cortex

artículo científico publicado en 1998

Combined application of excitatory amino acids and substance P produces long-lasting changes in responses of primate spinothalamic tract neurons

article

Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505).

artículo científico publicado en 2016

Cyclooxygenase inhibitors and thalidomide ameliorate vincristine-induced hyperalgesia in rats

artículo científico publicado en 2004

Cyclosporine affects central nervous system opioid activity via direct and indirect means

artículo científico publicado en 1988

DRG Voltage-gated Sodium Channel 1.7 is Up-regulated in Paclitaxel-Induced Neuropathy in Rats and in Humans with Neuropathic Pain.

artículo científico publicado en 2017

Differential influence of local anesthetic upon two models of experimentally induced peripheral mononeuropathy in the rat.

artículo científico publicado en 1992

Differential modification of morphine and methadone dependence by interferon alpha

scientific article published on 01 November 1987

Distribution of cardiovascular related cells within the human thalamus

artículo científico publicado en 1998

Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy

artículo científico publicado en 2016

Dynamic effects of TNF-α on synaptic transmission in mice over time following sciatic nerve chronic constriction injury

artículo científico publicado en 2013

Dysfunction in Multiple Primary Afferent Fiber Subtypes Revealed By Quantitative Sensory Testing in Patients with Chronic Vincristine-Induced Pain

artículo científico publicado en 2007

Effect of Fenoldopam on Ischemia/Reperfusion-Induced Apoptosis

artículo científico publicado en 2006

Effects of isoflurane, pentobarbital, and urethane on apoptosis and apoptotic signal transduction in rat kidney

artículo científico publicado en 2006

Effects of microiontophoretic application of cocaine, alone and with receptor antagonists, upon the neurons of the medial prefrontal cortex, nucleus accumbens and caudate nucleus of rats

artículo científico publicado en 1990

Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy

artículo científico publicado en 2014

Enhancement of spinothalamic neuron responses to chemical and mechanical stimuli following combined micro-iontophoretic application of N-methyl-D-aspartic acid and substance P.

artículo científico publicado en 1991

Evidence of an immune system to brain communication axis that affects central opioid functions: muramyl peptides attenuate opiate withdrawal

artículo científico publicado en 1987

Evidence of neuro-immunologic interactions: cyclosporine modifies opiate withdrawal by effects on the brain and immune components

artículo científico publicado en 1987

Evidence that excitatory amino acids mediate afferent input to the primate somatosensory thalamus

artículo científico publicado en 1996

Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of Paclitaxel-induced painful neuropathy

artículo científico publicado en 2012

Facilitation of responses to AMPA but not kainate by cyclothiazide in primate somatosensory thalamus

artículo científico publicado en 1998

Follow-up psychophysical studies in bortezomib-related chemoneuropathy patients

artículo científico publicado en 2011

Functional plasticity in primate somatosensory thalamus following chronic lesion of the ventral lateral spinal cord

scientific article published on 01 January 2000

GFAP Expression in Lumbar Spinal Cord of Naive and Neuropathic Rats Treated with MK-801

artículo científico publicado en 1994

Gabapentin produces dose-dependent antinociception in the orofacial formalin test in the rat.

artículo científico publicado en 2002

Ghrelin prevents cisplatin-induced mechanical hyperalgesia and cachexia

artículo científico publicado en 2007

Higher Stem Cell Dose Infusion after Intensive Chemotherapy Does Not Improve Symptom Burden in Older Patients with Multiple Myeloma and Amyloidosis

artículo científico publicado en 2015

Induction of monocyte chemoattractant protein-1 (MCP-1) and its receptor CCR2 in primary sensory neurons contributes to paclitaxel-induced peripheral neuropathy

artículo científico publicado en 2013

Infusion of substance P or neurokinin A by microdialysis alters responses of primate spinothalamic tract neurons to cutaneous stimuli and to iontophoretically released excitatory amino acids

article

Internal pallidal neuronal activity during mild drug-related dyskinesias in Parkinson's disease: decreased firing rates and altered firing patterns

artículo científico publicado en 2007

Intraepidermal nerve fiber loss corresponds to the development of taxol-induced hyperalgesia and can be prevented by treatment with minocycline

artículo científico publicado en 2010

Irradiation exposure modulates central opioid functions

artículo científico publicado en 1987

Is Chemotherapy-induced Peripheral Neuropathy More Than Just a Peripheral Nervous System Disorder?

artículo científico publicado en 2016

Is large myelinated fiber loss associated with hyperalgesia in a model of experimental peripheral neuropathy in the rat?

artículo científico publicado en 1993

MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy

artículo científico publicado en 2015

Measuring Therapy-Induced Peripheral Neuropathy: Preliminary Development and Validation of the Treatment-Induced Neuropathy Assessment Scale

artículo científico publicado en 2015

Mechanical and thermal hypersensitivity develops following kainate lesion of the ventral posterior lateral thalamus in rats

artículo científico publicado en 2000

Microiontophoresis of cocaine, desipramine, sulpiride, methysergide, and naloxone in habenula and parafasciculus

artículo científico publicado en 1990

Microiontophoretic application of muramyl-dipeptide upon single cortical, hippocampal and hypothalamic neurons in rats

artículo científico publicado en 1990

Minocycline blocks lipopolysaccharide induced hyperalgesia by suppression of microglia but not astrocytes.

artículo científico publicado en 2012

Modification of the responses of primate spinothalamic neurons to mechanical stimulation by excitatory amino acids and an N-methyl-D-aspartate antagonist

artículo científico publicado en 1991

Monkey insular cortex neurons respond to baroreceptive and somatosensory convergent inputs

scientific article published on 01 January 1999

Muramyl-dipeptide, a macrophage-derived cytokine, alters neuronal activity in hypothalamus and hippocampus but not in the dorsal raphe/periaqueductal gray of rats

artículo científico publicado en 1990

Neural changes in acute arthritis in monkeys. I. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids

article

Neural changes in acute arthritis in monkeys. II. Increased glutamate immunoreactivity in the medial articular nerve

artículo científico publicado en 1992

Neural changes in acute arthritis in monkeys. III. Changes in substance P, calcitonin gene-related peptide and glutamate in the dorsal horn of the spinal cord

article

Neural changes in acute arthritis in monkeys. IV. Time-course of amino acid release into the lumbar dorsal horn

scientific article published on 01 January 1992

Neuroma formation and numbers of axons in a rat model of experimental peripheral neuropathy

artículo científico publicado en 1991

Neuronal activity in the region of the thalamic principal sensory nucleus (ventralis caudalis) in patients with pain following amputations

artículo científico publicado en 1998

Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain

scientific article published on 20 November 2018

Noninvasive subthreshold auricular electrical stimulation reduces the severity of precipitated and abrupt opiate withdrawal

artículo científico publicado en 1993

Opiate antinociception is altered by immunemodification: the effect of interferon, cyclosporine and radiation-induced immune suppression upon acute and long-term morphine activity

artículo científico publicado en 1986

Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity

artículo científico publicado en 2009

Pain Encoding in the Human Forebrain: Binary and Analog Exteroceptive Channels

scientific article published on 01 July 2004

Pain and Temperature Encoding in the Human Thalamic Somatic Sensory Nucleus (Ventral caudal): Inhibition-Related Bursting Evoked by Somatic Stimuli

artículo científico publicado en 2005

Painful Hands and Feet After Cancer Treatment: Inflammation Affecting the Mind-Body Connection

artículo científico publicado en 2015

Pallidotomy for hemiballismus: efficacy and characteristics of neuronal activity

artículo científico publicado en 1997

Participation of lymphoid cells in the withdrawal syndrome of opiate dependent rats

artículo científico publicado en 1987

Patterns of bursting occurring in thalamic cells during parkinsonian tremor

artículo científico publicado en 1998

Peripheral neuropathic pain: signs, symptoms, mechanisms, and causes: are they linked?

artículo científico publicado en 2014

Persistent chemoneuropathy in patients receiving the plant alkaloids paclitaxel and vincristine

artículo científico publicado en 2012

Physiological changes in primate somatosensory thalamus induced by deafferentation are dependent on the spinal funiculi that are sectioned and time following injury

artículo científico publicado en 2003

Plasticity in expression of the glutamate transporters GLT-1 and GLAST in spinal dorsal horn glial cells following partial sciatic nerve ligation

artículo científico publicado en 2009

Postoperative MRI Evaluation of a Radiofrequency Cordotomy Lesion for Intractable Cancer Pain.

artículo científico publicado en 2017

Prechemotherapy Touch Sensation Deficits Predict Oxaliplatin-Induced Neuropathy in Patients with Colorectal Cancer

artículo científico publicado en 2016

Protection against oxaliplatin-induced mechanical hyperalgesia and intraepidermal nerve fiber loss by minocycline

artículo científico publicado el 5 de marzo de 2011

Psychophysical elements of place and modality specificity in the thalamic somatic sensory nucleus (ventral caudal, vc) of awake humans

artículo científico publicado en 2005

Quantitative Sensory Findings in Patients With Bortezomib-Induced Pain

artículo científico publicado en 2006

Quantitative analysis of substance P and calcitonin gene-related peptide immunohistochemical staining in the dorsal horn of neuropathic MK-801-treated rats

artículo científico publicado en 1993

Relationship of membrane properties, spike burst responses, laminar location, and functional class of dorsal horn neurons recorded in vitro

artículo científico publicado en 2016

Response properties of dorsal root reflexes in cutaneous C fibers before and after intradermal capsaicin injection in rats

artículo científico publicado en 2005

Responses of primate spinomesencephalic tract cells to intradermal capsaicin

artículo científico publicado en 1999

Reversing tissue injury-induced plastic changes in the spinal cord: the search for the magic bullet

artículo científico publicado en 2000

Role of nuclear factor κB-mediated inflammatory pathways in cancer-related symptoms and their regulation by nutritional agents

artículo científico publicado en 2011

Sensitization of dorsal root reflexes in vitro and hyperalgesia in neonatal rats produced by capsaicin

artículo científico publicado en 2004

Spinal astrocyte gap junction and glutamate transporter expression contributes to a rat model of bortezomib-induced peripheral neuropathy

artículo científico publicado en 2014

Spinal astrocyte gap junctions contribute to oxaliplatin-induced mechanical hypersensitivity

artículo científico publicado en 2013

Spinal cord stimulation relieves chemotherapy-induced pain: a clinical case report

artículo científico publicado en 2004

Spinal glial glutamate transporters downregulate in rats with taxol-induced hyperalgesia.

artículo científico publicado en 2005

Spinal injection of IL-2 or IL-15 alters mechanical and thermal withdrawal thresholds in rats

artículo científico publicado en 2008

Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury.

artículo científico publicado en 1991

Stimulation in the human somatosensory thalamus can reproduce both the affective and sensory dimensions of previously experienced pain

artículo científico publicado en 1995

Subclinical peripheral neuropathy in patients with multiple myeloma before chemotherapy is correlated with decreased fingertip innervation density

artículo científico publicado en 2014

Subclinical peripheral neuropathy is a common finding in colorectal cancer patients prior to chemotherapy

artículo científico publicado en 2012

Subclinical pretreatment sensory deficits appear to predict the development of pain and numbness in patients with multiple myeloma undergoing chemotherapy

artículo científico publicado en 2013

Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes

scientific article published on July 2009

Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients

artículo científico publicado en 2004

The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4

artículo científico publicado en 2015

The brain and the immune system: an intact immune system is essential for the manifestation of withdrawal in opiate addicted rats

artículo científico publicado en 1990

The effect of alpha-interferon, cyclosporine A, and radiation-induced immune suppression on morphine-induced hypothermia and tolerance

artículo científico publicado en 1986

The effect of trans-ACPD, a metabotropic excitatory amino acid receptor agonist, on the responses of primate spinothalamic tract neurons

artículo científico publicado en 1994

The effects of thalidomide and minocycline on taxol-induced hyperalgesia in rats

artículo científico publicado en 2008

The endogenous lectin RL-29 is transynaptically induced in dorsal horn neurons following peripheral neuropathy in the rat.

artículo científico publicado en 1993

The immune system and opiate withdrawal

scientific article published on 01 January 1989

The sensation of angina can be evoked by stimulation of the human thalamus

artículo científico publicado en 1994

Toll-like receptor 4 signaling contributes to Paclitaxel-induced peripheral neuropathy

artículo científico publicado en 2014

Trans-cranial electrical stimulation attenuates abrupt morphine withdrawal in rats assayed by remote computerized quantification of multiple motor behavior indices

artículo científico publicado en 1990

Trans-cranial electrical stimulation attenuates the severity of naloxone-precipitated morphine withdrawal in rats

scientific article published on 01 January 1989

Transient inhibition of responses to thermal stimuli of spinal sensory tract neurons in monkeys during sensitization by intradermal capsaicin

article

Tremor-frequency (3-6 Hz) activity in the sensorimotor arm representation of the internal segment of the globus pallidus in patients with Parkinson's disease

artículo científico publicado en 1999

Tuning of Membrane Properties Regulates Subliminal Synapses in Dorsal Horn Neurons of Intact Rats

artículo científico publicado en 2002

Two pains at once: How can you tell which is worse?

artículo científico publicado el 3 de febrero de 2012

Wireless peripheral nerve stimulation increases pain threshold in two neuropathic rat models

artículo científico publicado en 2012