Lista de obras - Antonino Lauria - Dominio Público Uruguay

1-Methyl-3H-pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-ones. Design, synthesis, and biological activity of new antitumor agents.

artículo científico publicado en 2005

2-Diazoindoles: building blocks for the synthesis of antineoplastic agents

artículo científico publicado en 2002

3D-QSAR pharmacophore modeling and in silico screening of new Bcl-xl inhibitors.

artículo científico publicado en 2010

A general treatment of solubility. 3. Principal component analysis (PCA) of the solubilities of diverse solutes in diverse solvents

scientific article published on 01 July 2005

A multivariate analysis of HIV-1 protease inhibitors and resistance induced by mutation

artículo científico publicado en 2006

A3 adenosine receptor: homology modeling and 3D-QSAR studies

artículo científico publicado en 2013

An unexpected Dimroth rearrangement leading to annelated thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with potent antitumor activity.

artículo científico publicado en 2013

Annelated pyrrolo-pyrimidines from amino-cyanopyrroles and BMMAs as leads for new DNA-interactive ring systems.

artículo científico publicado en 2005

Curcumin-like compounds designed to modify amyloid beta peptide aggregation patterns

scholarly article in RSC Advances, vol. 7 no. 50, 2017

DNA minor groove binders: an overview on molecular modeling and QSAR approaches.

artículo científico publicado en 2007

Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity

artículo científico publicado en 1999

Design and synthesis of 4-substituted indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine derivatives with antitumor activity

artículo científico publicado en 2008

Design, synthesis, and biological evaluation of a new class of benzo[b]furan derivatives as antiproliferative agents, with in silico predicted antitubulin activity

artículo científico publicado en 2017

Docking and multivariate methods to explore HIV-1 drug-resistance: a comparative analysis

artículo científico publicado en 2008

Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives: the effect on apoptosis induction, cell cycle and proliferation.

artículo científico publicado en 2013

Heterocyclic Scaffolds for the Treatment of Alzheimer's Disease

artículo científico publicado en 2016

Hsp60, a novel target for antitumor therapy: structure-function features and prospective drugs design

artículo científico

IKK-beta inhibitors: an analysis of drug-receptor interaction by using molecular docking and pharmacophore 3D-QSAR approaches.

artículo científico publicado en 2010

Identification of an LPS-Induced Chemo-Attractive Peptide from Ciona robusta

scientific article published on 12 April 2020

In Silico Insights into the SARS CoV-2 Main Protease Suggest NADH Endogenous Defences in the Control of the Pandemic Coronavirus Infection

artículo científico publicado en 2020

In vitro and in silico studies of polycondensed diazine systems as anti-parasitic agents.

artículo científico publicado en 2011

In-silico screening of new potential Bcl-2/Bcl-xl inhibitors as apoptosis modulators

scientific article published on 06 December 2008

Indolo[3,2-c]cinnolines with antiproliferative, antifungal, and antibacterial activity

artículo científico publicado en 1999

Inside the Hsp90 inhibitors binding mode through induced fit docking.

artículo científico publicado en 2008

Isoindolo[2,1-c]benzo[1,2,4]triazines: a new ring system with antiproliferative activity.

artículo científico publicado en 2006

Lead optimization through VLAK protocol: new annelated pyrrolo-pyrimidine derivatives as antitumor agents.

artículo científico publicado en 2012

Molecular docking approach on the Topoisomerase I inhibitors series included in the NCI anti-cancer agents mechanism database

artículo científico publicado en 2006

Molecular dynamics studies on HIV-1 protease: a comparison of the flap motions between wild type protease and the M46I/G51D double mutant

scientific article published on 06 September 2007

Molecular dynamics studies on Mdm2 complexes: an analysis of the inhibitor influence

artículo científico publicado en 2012

Molecular dynamics, dynamic site mapping, and highthroughput virtual screening on leptin and the Ob receptor as anti-obesity target.

artículo científico

Molecular modeling approaches in the discovery of new drugs for anti-cancer therapy: the investigation of p53-MDM2 interaction and its inhibition by small molecules.

scientific article published on January 2010

Multivariate analysis in the identification of biological targets for designed molecular structures: the BIOTA protocol

artículo científico publicado en 2014

New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol.

artículo científico publicado en 2013

New benzothieno[3,2-d]-1,2,3-triazines with antiproliferative activity: synthesis, spectroscopic studies, and biological activity.

artículo científico publicado en 2014

Nickel(II), copper(II) and zinc(II) metallo-intercalators: structural details of the DNA-binding by a combined experimental and computational investigation

scientific article published on 01 April 2014

Principal component analysis on molecular descriptors as an alternative point of view in the search of new Hsp90 inhibitors

artículo científico publicado en 2009

Pyrrolo[1,2-f]phenanthridines and related non-rigid analogues as antiviral agents

artículo científico publicado en 2002

Pyrrolo[2,1-c][1,2,4]triazines from 2-diazopyrroles: synthesis and antiproliferative activity

artículo científico publicado en 2002

Pyrrolo[2,1-d][1,2,3,5]tetrazine-4(3H)-ones, a new class of azolotetrazines with potent antitumor activity.

artículo científico publicado en 2003

Pyrrolo[2,1-d][1,2,3,5]tetrazinones deaza analogues of temozolomide with potent antitumor activity

scientific article published on 01 March 2000

Pyrrolo[2,3-h]quinolinones: synthesis and photochemotherapic activity

artículo científico publicado en 2003

Quinoline-Based Molecules Targeting c-Met, EGF, and VEGF Receptors and the Proteins Involved in Related Carcinogenic Pathways

scientific article published on 18 September 2020

Receptor-guided 3D-QSAR approach for the discovery of c-kit tyrosine kinase inhibitors ⬇️

artículo científico publicado el 30 de noviembre de 2011

Synthesis and antiproliferative activity of [1,2,3,5]tetrazino[5,4-a]indoles, a new class of azolo-tetrazinones.

artículo científico publicado en 2005

Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening.

artículo científico publicado en 2013

Synthesis and photochemotherapeutic activity of thiopyrano[2,3-e]indol-2-ones

artículo científico publicado en 2005

Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[b]thiophene derivatives

artículo científico publicado en 2014

The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA.

artículo científico publicado en 2017

Virtual lock-and-key approach: The in silico revival of Fischer model by means of molecular descriptors ⬇️

artículo científico publicado el 1 de julio de 2011

Zinc complexes as fluorescent chemosensors for nucleic acids: new perspectives for a "boring" element

artículo científico publicado en 2015

Lista de obras de Antonino Lauria

1-Methyl-3H-pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-ones. Design, synthesis, and biological activity of new antitumor agents.

2-Diazoindoles: building blocks for the synthesis of antineoplastic agents

3D-QSAR pharmacophore modeling and in silico screening of new Bcl-xl inhibitors.

A general treatment of solubility. 3. Principal component analysis (PCA) of the solubilities of diverse solutes in diverse solvents

A multivariate analysis of HIV-1 protease inhibitors and resistance induced by mutation

A3 adenosine receptor: homology modeling and 3D-QSAR studies

An unexpected Dimroth rearrangement leading to annelated thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with potent antitumor activity.

Annelated pyrrolo-pyrimidines from amino-cyanopyrroles and BMMAs as leads for new DNA-interactive ring systems.

Curcumin-like compounds designed to modify amyloid beta peptide aggregation patterns

DNA minor groove binders: an overview on molecular modeling and QSAR approaches.

Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity

Design and synthesis of 4-substituted indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine derivatives with antitumor activity

Design, synthesis, and biological evaluation of a new class of benzo[b]furan derivatives as antiproliferative agents, with in silico predicted antitubulin activity

Docking and multivariate methods to explore HIV-1 drug-resistance: a comparative analysis

Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives: the effect on apoptosis induction, cell cycle and proliferation.

Heterocyclic Scaffolds for the Treatment of Alzheimer's Disease

Hsp60, a novel target for antitumor therapy: structure-function features and prospective drugs design

IKK-beta inhibitors: an analysis of drug-receptor interaction by using molecular docking and pharmacophore 3D-QSAR approaches.

Identification of an LPS-Induced Chemo-Attractive Peptide from Ciona robusta

In Silico Insights into the SARS CoV-2 Main Protease Suggest NADH Endogenous Defences in the Control of the Pandemic Coronavirus Infection

In vitro and in silico studies of polycondensed diazine systems as anti-parasitic agents.

In-silico screening of new potential Bcl-2/Bcl-xl inhibitors as apoptosis modulators

Indolo[3,2-c]cinnolines with antiproliferative, antifungal, and antibacterial activity

Inside the Hsp90 inhibitors binding mode through induced fit docking.

Isoindolo[2,1-c]benzo[1,2,4]triazines: a new ring system with antiproliferative activity.

Lead optimization through VLAK protocol: new annelated pyrrolo-pyrimidine derivatives as antitumor agents.

Molecular docking approach on the Topoisomerase I inhibitors series included in the NCI anti-cancer agents mechanism database

Molecular dynamics studies on HIV-1 protease: a comparison of the flap motions between wild type protease and the M46I/G51D double mutant

Molecular dynamics studies on Mdm2 complexes: an analysis of the inhibitor influence

Molecular dynamics, dynamic site mapping, and highthroughput virtual screening on leptin and the Ob receptor as anti-obesity target.

Molecular modeling approaches in the discovery of new drugs for anti-cancer therapy: the investigation of p53-MDM2 interaction and its inhibition by small molecules.

Multivariate analysis in the identification of biological targets for designed molecular structures: the BIOTA protocol

New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol.

New benzothieno[3,2-d]-1,2,3-triazines with antiproliferative activity: synthesis, spectroscopic studies, and biological activity.

Nickel(II), copper(II) and zinc(II) metallo-intercalators: structural details of the DNA-binding by a combined experimental and computational investigation

Principal component analysis on molecular descriptors as an alternative point of view in the search of new Hsp90 inhibitors

Pyrrolo[1,2-f]phenanthridines and related non-rigid analogues as antiviral agents

Pyrrolo[2,1-c][1,2,4]triazines from 2-diazopyrroles: synthesis and antiproliferative activity

Pyrrolo[2,1-d][1,2,3,5]tetrazine-4(3H)-ones, a new class of azolotetrazines with potent antitumor activity.

Pyrrolo[2,1-d][1,2,3,5]tetrazinones deaza analogues of temozolomide with potent antitumor activity

Pyrrolo[2,3-h]quinolinones: synthesis and photochemotherapic activity

Quinoline-Based Molecules Targeting c-Met, EGF, and VEGF Receptors and the Proteins Involved in Related Carcinogenic Pathways

Receptor-guided 3D-QSAR approach for the discovery of c-kit tyrosine kinase inhibitors ⬇️

Synthesis and antiproliferative activity of [1,2,3,5]tetrazino[5,4-a]indoles, a new class of azolo-tetrazinones.

Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening.

Synthesis and photochemotherapeutic activity of thiopyrano[2,3-e]indol-2-ones

Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[b]thiophene derivatives

The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA.

Virtual lock-and-key approach: The in silico revival of Fischer model by means of molecular descriptors ⬇️

Zinc complexes as fluorescent chemosensors for nucleic acids: new perspectives for a "boring" element