Lista de obras - Dean A Lee - Dominio Público Uruguay

A Novel Method for Assessment of Natural Killer Cell Cytotoxicity Using Image Cytometry

artículo científico publicado en 2015

A high throughput microelectroporation device to introduce a chimeric antigen receptor to redirect the specificity of human T cells

artículo científico publicado en 2010

Acquisition, preparation, and functional assessment of human NK cells for adoptive immunotherapy

artículo científico publicado en 2010

Activated peripheral T lymphocytes undergo apoptosis when cultured with monocytes activated by HLA class II ligation

artículo científico publicado en 2003

Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies

artículo científico publicado en 2014

Advances in clinical NK cell studies: Donor selection, manufacturing and quality control

artículo científico publicado en 2015

Aerosol interleukin-2 induces natural killer cell proliferation in the lung and combination therapy improves the survival of mice with osteosarcoma lung metastasis.

artículo científico publicado en 2014

Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells.

artículo científico publicado en 2014

Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity.

artículo científico publicado en 2013

Autologous bone marrow mononuclear cell therapy for severe traumatic brain injury in children

artículo científico publicado en 2011

Autologous bone marrow mononuclear cells reduce therapeutic intensity for severe traumatic brain injury in children

artículo científico publicado en 2015

Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection.

artículo científico publicado en 2014

Bispecific T-cells Expressing Polyclonal Repertoire of Endogenous γδ T-cell Receptors and Introduced CD19-specific Chimeric Antigen Receptor ⬇️

artículo científico publicado el 8 de enero de 2013

C/EBPbeta suppression by interruption of CUGBP1 resulting from a complex rearrangement of MLL.

artículo científico publicado en 2007

Cellular engineering and therapy in combination with cord blood allografting in pediatric recipients

artículo científico

Cellular therapy: Adoptive immunotherapy with expanded natural killer cells

artículo científico publicado en 2019

Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials

artículo científico publicado en 2013

Chromatin remodelling at the topoisomerase II-beta promoter is associated with enhanced sensitivity to etoposide in human neuroblastoma cell lines

artículo científico publicado en 2010

Clinical-scale derivation of natural killer cells from human pluripotent stem cells for cancer therapy.

artículo científico publicado en 2013

Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies.

artículo científico publicado en 2010

Cytotoxicity of CD56-positive lymphocytes against autologous B-cell precursor acute lymphoblastic leukemia cells

artículo científico publicado en 2014

Decitabine has a biphasic effect on natural killer cell viability, phenotype, and function under proliferative conditions

artículo científico publicado en 2013

Defining and managing career challenges for mid-career and senior stage pediatric hematologist/oncologists

artículo científico publicado en 2010

EBV+ lymphoproliferative disease following prolonged chemotherapy for refractory LCH.

artículo científico publicado en 2008

Engineering lymph node homing of ex vivo-expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7.

artículo científico publicado en 2012

Evaluation of serum-free media formulations in feeder cell-stimulated expansion of natural killer cells

artículo científico publicado en 2020

Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells ⬇️

artículo científico publicado el 2 de febrero de 2011

Expression of carcinoma, apoptosis, and cell-death-related genes are determinants for sensitivity of pediatric cancer cell lines to lysis by natural killer cells

scientific article published on 15 July 2019

Fenretinide sensitizes multidrug-resistant human neuroblastoma cells to antibody-independent and ch14.18-mediated NK cell cytotoxicity.

artículo científico publicado en 2012

Granulocytic sarcoma presenting as pneumonia in a child with t(8;21) acute myelogenous leukemia: diagnosis by fluorescent in situ hybridization

artículo científico publicado en 2004

HIV false positivity after hepatitis B vaccination

artículo científico publicado en 1992

Haploidentical Hematopoietic Stem Cell Transplantation as a Platform for Post-Transplantation Cellular Therapy

artículo científico publicado en 2015

Haploidentical Natural Killer Cells Infused before Allogeneic Stem Cell Transplantation for Myeloid Malignancies: A Phase I Trial

artículo científico publicado en 2016

IL-12 and IL-27 sequential gene therapy via intramuscular electroporation delivery for eliminating distal aggressive tumors.

artículo científico publicado en 2010

Identifying candidate allogeneic NK-cell donors for hematopoietic stem-cell transplantation based on functional phenotype.

artículo científico publicado en 2010

Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography

artículo científico publicado en 2016

Immune profiles of desmoplastic small round cell tumor and synovial sarcoma suggest different immunotherapeutic susceptibility upfront compared to relapse specimens

scientific article published on 17 July 2018

In Vitro and In Vivo Antitumor Effect of Anti-CD33 Chimeric Receptor-Expressing EBV-CTL against CD33 Acute Myeloid Leukemia

artículo científico publicado en 2012

Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies.

artículo científico publicado en 2012

Investigation of donor KIR content and matching in children undergoing hematopoietic cell transplantation for acute leukemia

scientific article published on 01 April 2020

Is there an expiration date for a cord blood unit in storage?

artículo científico publicado en 2014

Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells

artículo científico publicado en 2012

Membrane-bound TRAIL Supplements Natural Killer Cell Cytotoxicity Against Neuroblastoma Cells ⬇️

artículo científico publicado el 1 de junio de 2013

Mentoring in pediatric oncology: a report from the Children's Oncology Group Young Investigator Committee

scientific article published on August 2013

NK cell therapy: targeting disease relapse after hematopoietic stem cell transplantation

artículo científico publicado en 2012

Natural killer cell adoptive immunotherapy: Coming of age.

artículo científico publicado en 2016

Natural killer cell therapy and aerosol interleukin-2 for the treatment of osteosarcoma lung metastasis.

artículo científico publicado en 2013

Natural killer cells for osteosarcoma.

artículo científico publicado en 2014

Natural killer cells stimulated with PM21 particles expand and biodistribute in vivo: Clinical implications for cancer treatment.

artículo científico publicado en 2016

New insights to the MLL recombinome of acute leukemias

artículo científico publicado en 2009

Phase I study of cord blood-derived natural killer cells combined with autologous stem cell transplantation in multiple myeloma

artículo científico publicado en 2017

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

artículo científico publicado en 2016

Recurrent Stimulation of Natural Killer Cell Clones with K562 Expressing Membrane-Bound Interleukin-21 Affects Their Phenotype, Interferon-γ Production, and Lifespan

artículo científico publicado en 2019

Redirecting T-Cell Specificity to EGFR Using mRNA to Self-limit Expression of Chimeric Antigen Receptor

artículo científico publicado en 2016

Repression of GSK3 restores NK cell cytotoxicity in AML patients

artículo científico publicado en 2016

Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies.

artículo científico publicado en 2011

Results of a 2-arm, phase 2 clinical trial using post-transplantation cyclophosphamide for the prevention of graft-versus-host disease in haploidentical donor and mismatched unrelated donor hematopoietic stem cell transplantation

artículo científico publicado en 2016

Rotavirus vaccines

artículo científico publicado en 2006

Similar transplantation outcomes for acute myeloid leukemia and myelodysplastic syndrome patients with haploidentical versus 10/10 human leukocyte antigen-matched unrelated and related donors.

artículo científico publicado en 2014

Sleeping Beauty System to Redirect T-cell Specificity for Human Applications ⬇️

artículo científico publicado el 1 de febrero de 2013

Strategies for combining immunotherapy with radiation for anticancer therapy

artículo científico publicado en 2015

T cells redirected to EphA2 for the immunotherapy of glioblastoma

artículo científico publicado en 2012

The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor

artículo científico publicado en 2011

The narrow-spectrum HDAC inhibitor entinostat enhances NKG2D expression without NK cell toxicity, leading to enhanced recognition of cancer cells

artículo científico publicado en 2013

The off-target effects of nonspecific NK cells

artículo científico publicado en 2015

Toward eliminating HLA class I expression to generate universal cells from allogeneic donors

artículo científico publicado en 2013

Trace Evidence: Identifying Natural Cancer Killers After the Crime.

artículo científico publicado en 2015

Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation.

artículo científico publicado en 2014

Trastuzumab upregulates expression of HLA-ABC and T cell costimulatory molecules through engagement of natural killer cells and stimulation of IFNγ secretion.

artículo científico publicado en 2015

Tumor lysing genetically engineered T cells loaded with multi-modal imaging agents

artículo científico publicado en 2014

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy

artículo científico publicado en 2004

Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity

artículo científico publicado en 2015

Universal artificial antigen presenting cells to selectively propagate T cells expressing chimeric antigen receptor independent of specificity

artículo científico publicado en 2014

Venous Thromboembolism in Pediatric Hematopoietic Cell Transplant: A Multicenter Cohort Study.

artículo científico publicado en 2017

piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies

artículo científico publicado en 2010

Lista de obras de Dean A Lee

A Novel Method for Assessment of Natural Killer Cell Cytotoxicity Using Image Cytometry

A high throughput microelectroporation device to introduce a chimeric antigen receptor to redirect the specificity of human T cells

Acquisition, preparation, and functional assessment of human NK cells for adoptive immunotherapy

Activated peripheral T lymphocytes undergo apoptosis when cultured with monocytes activated by HLA class II ligation

Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies

Advances in clinical NK cell studies: Donor selection, manufacturing and quality control

Aerosol interleukin-2 induces natural killer cell proliferation in the lung and combination therapy improves the survival of mice with osteosarcoma lung metastasis.

Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells.

Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity.

Autologous bone marrow mononuclear cell therapy for severe traumatic brain injury in children

Autologous bone marrow mononuclear cells reduce therapeutic intensity for severe traumatic brain injury in children

Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection.

Bispecific T-cells Expressing Polyclonal Repertoire of Endogenous γδ T-cell Receptors and Introduced CD19-specific Chimeric Antigen Receptor ⬇️

C/EBPbeta suppression by interruption of CUGBP1 resulting from a complex rearrangement of MLL.

Cellular engineering and therapy in combination with cord blood allografting in pediatric recipients

Cellular therapy: Adoptive immunotherapy with expanded natural killer cells

Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials

Chromatin remodelling at the topoisomerase II-beta promoter is associated with enhanced sensitivity to etoposide in human neuroblastoma cell lines

Clinical-scale derivation of natural killer cells from human pluripotent stem cells for cancer therapy.

Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies.

Cytotoxicity of CD56-positive lymphocytes against autologous B-cell precursor acute lymphoblastic leukemia cells

Decitabine has a biphasic effect on natural killer cell viability, phenotype, and function under proliferative conditions

Defining and managing career challenges for mid-career and senior stage pediatric hematologist/oncologists

EBV+ lymphoproliferative disease following prolonged chemotherapy for refractory LCH.

Engineering lymph node homing of ex vivo-expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7.

Evaluation of serum-free media formulations in feeder cell-stimulated expansion of natural killer cells

Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells ⬇️

Expression of carcinoma, apoptosis, and cell-death-related genes are determinants for sensitivity of pediatric cancer cell lines to lysis by natural killer cells

Fenretinide sensitizes multidrug-resistant human neuroblastoma cells to antibody-independent and ch14.18-mediated NK cell cytotoxicity.

Granulocytic sarcoma presenting as pneumonia in a child with t(8;21) acute myelogenous leukemia: diagnosis by fluorescent in situ hybridization

HIV false positivity after hepatitis B vaccination

Haploidentical Hematopoietic Stem Cell Transplantation as a Platform for Post-Transplantation Cellular Therapy

Haploidentical Natural Killer Cells Infused before Allogeneic Stem Cell Transplantation for Myeloid Malignancies: A Phase I Trial

IL-12 and IL-27 sequential gene therapy via intramuscular electroporation delivery for eliminating distal aggressive tumors.

Identifying candidate allogeneic NK-cell donors for hematopoietic stem-cell transplantation based on functional phenotype.

Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography

Immune profiles of desmoplastic small round cell tumor and synovial sarcoma suggest different immunotherapeutic susceptibility upfront compared to relapse specimens

In Vitro and In Vivo Antitumor Effect of Anti-CD33 Chimeric Receptor-Expressing EBV-CTL against CD33 Acute Myeloid Leukemia

Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies.

Investigation of donor KIR content and matching in children undergoing hematopoietic cell transplantation for acute leukemia

Is there an expiration date for a cord blood unit in storage?

Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells

Membrane-bound TRAIL Supplements Natural Killer Cell Cytotoxicity Against Neuroblastoma Cells ⬇️

Mentoring in pediatric oncology: a report from the Children's Oncology Group Young Investigator Committee

NK cell therapy: targeting disease relapse after hematopoietic stem cell transplantation

Natural killer cell adoptive immunotherapy: Coming of age.

Natural killer cell therapy and aerosol interleukin-2 for the treatment of osteosarcoma lung metastasis.

Natural killer cells for osteosarcoma.

Natural killer cells stimulated with PM21 particles expand and biodistribute in vivo: Clinical implications for cancer treatment.

New insights to the MLL recombinome of acute leukemias

Phase I study of cord blood-derived natural killer cells combined with autologous stem cell transplantation in multiple myeloma

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

Recurrent Stimulation of Natural Killer Cell Clones with K562 Expressing Membrane-Bound Interleukin-21 Affects Their Phenotype, Interferon-γ Production, and Lifespan

Redirecting T-Cell Specificity to EGFR Using mRNA to Self-limit Expression of Chimeric Antigen Receptor

Repression of GSK3 restores NK cell cytotoxicity in AML patients

Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies.

Results of a 2-arm, phase 2 clinical trial using post-transplantation cyclophosphamide for the prevention of graft-versus-host disease in haploidentical donor and mismatched unrelated donor hematopoietic stem cell transplantation

Rotavirus vaccines

Similar transplantation outcomes for acute myeloid leukemia and myelodysplastic syndrome patients with haploidentical versus 10/10 human leukocyte antigen-matched unrelated and related donors.

Sleeping Beauty System to Redirect T-cell Specificity for Human Applications ⬇️

Strategies for combining immunotherapy with radiation for anticancer therapy

T cells redirected to EphA2 for the immunotherapy of glioblastoma

The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor

The narrow-spectrum HDAC inhibitor entinostat enhances NKG2D expression without NK cell toxicity, leading to enhanced recognition of cancer cells

The off-target effects of nonspecific NK cells

Toward eliminating HLA class I expression to generate universal cells from allogeneic donors

Trace Evidence: Identifying Natural Cancer Killers After the Crime.

Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation.

Trastuzumab upregulates expression of HLA-ABC and T cell costimulatory molecules through engagement of natural killer cells and stimulation of IFNγ secretion.

Tumor lysing genetically engineered T cells loaded with multi-modal imaging agents

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy

Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity

Universal artificial antigen presenting cells to selectively propagate T cells expressing chimeric antigen receptor independent of specificity

Venous Thromboembolism in Pediatric Hematopoietic Cell Transplant: A Multicenter Cohort Study.

piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies