Lista de obras - James Dooley - Dominio Público Uruguay

Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism

artículo científico publicado en 2012

Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation.

artículo científico publicado en 2007

Alterations of the medullary epithelial compartment in the Aire-deficient thymus: implications for programs of thymic epithelial differentiation

scientific article published on October 2008

An organized medullary epithelial structure in the normal thymus expresses molecules of respiratory epithelium and resembles the epithelial thymic rudiment of nude mice

artículo científico publicado en 2005

An orthologous non-MHC locus in rats and mice is linked to CD4(+) and CD8(+) T-cell proportion

artículo científico publicado en 2017

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells

artículo científico publicado en 2013

Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation

artículo científico publicado en 2022

C-kit is important for SOD1(G93A) mouse survival independent of mast cells.

artículo científico publicado en 2015

Cervical thymus in the mouse

artículo científico publicado en 2006

Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice

artículo científico publicado en 2017

Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice

artículo científico publicado en 2014

Developmental regulation of Foxp3 expression during ontogeny.

artículo científico publicado en 2005

Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS.

artículo científico publicado en 2017

FGFR2IIIb signaling regulates thymic epithelial differentiation

artículo científico publicado en 2007

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. ⬇️

artículo científico publicado en 2016

Foxp3⁺ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis.

artículo científico publicado en 2011

Gain-of-function mutations in signal transducer and activator of transcription 1 (STAT1): chronic mucocutaneous candidiasis accompanied by enamel defects and delayed dental shedding.

artículo científico publicado en 2014

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

artículo científico publicado en 2016

Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency.

artículo científico publicado en 2014

Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

artículo científico publicado en 2016

IL-2 consumption by highly activated CD8 T cells induces regulatory T-cell dysfunction in patients with hemophagocytic lymphohistiocytosis

artículo científico publicado en 2016

Immunological ignorance allows long-term gene expression after perinatal recombinant adeno-associated virus-mediated gene transfer to murine airways

artículo científico publicado en 2014

Irf4 Expression in Thymic Epithelium Is Critical for Thymic Regulatory T Cell Homeostasis

artículo científico publicado en 2017

Lessons from thymic epithelial heterogeneity: FoxN1 and tissue-restricted gene expression by extrathymic, endodermally derived epithelium.

artículo científico publicado en 2009

Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development

artículo científico publicado en 2007

Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice.

artículo científico publicado en 2012

MicroRNA regulation of T-cell development.

artículo científico

MicroRNA-29 in the adaptive immune system: setting the threshold.

artículo científico

Models of aire-dependent gene regulation for thymic negative selection.

artículo científico

Molecular control over thymic involution: from cytokines and microRNA to aging and adipose tissue

artículo científico publicado en 2012

Murine Pancreatic Acinar Cell Carcinoma Growth Kinetics Are Independent of Dietary Vitamin D Deficiency or Supplementation

artículo científico publicado en 2017

NOD mice, susceptible to pancreatic autoimmunity, demonstrate delayed growth of pancreatic cancer

artículo científico publicado en 2017

No Effect of Dietary Aspartame or Stevia on Pancreatic Acinar Carcinoma Development, Growth, or Induced Mortality in a Murine Model

artículo científico publicado en 2017

No Functional Role for microRNA-342 in a Mouse Model of Pancreatic Acinar Carcinoma.

artículo científico publicado en 2017

No evidence for a role of rareCYP27B1functional variations in multiple sclerosis

artículo científico publicado en 2013

Nude thymic rudiment lacking functional foxn1 resembles respiratory epithelium.

artículo científico publicado en 2005

Organization of thymic medullary epithelial heterogeneity: implications for mechanisms of epithelial differentiation.

artículo científico publicado en 2002

Premature thymic involution is independent of structural plasticity of the thymic stroma.

artículo científico publicado en 2015

Programmed cell death-1 expression correlates with disease severity and IL-5 in chronic rhinosinusitis with nasal polyps

artículo científico publicado en 2017

Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3⁺ and Foxp3⁻ T cells

artículo científico publicado en 2014

Psychological comorbidity increases the risk for postinfectious IBS partly by enhanced susceptibility to develop infectious gastroenteritis

artículo científico publicado en 2015

Rapamycin increases survival in ALS mice lacking mature lymphocytes.

scientific article published on 11 September 2013

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition

artículo científico publicado en 2019

The cellular composition of the human immune system is shaped by age and cohabitation.

artículo científico publicado en 2016

The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity

artículo científico publicado en 2016

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

artículo científico publicado en 2011

The thymic niche does not limit development of the naturally diverse population of mouse regulatory T lymphocytes

artículo científico publicado en 2012

The thymoprotective function of leptin is indirectly mediated via suppression of obesity.

artículo científico publicado en 2015

Transcriptional upregulation of myelin components in spontaneous myelin basic protein-deficient mice.

artículo científico publicado en 2015

miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a

artículo científico publicado en 2015

miR-29a-deficiency does not modify the course of murine pancreatic acinar carcinoma.

artículo científico publicado en 2017

Lista de obras de James Dooley

Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism

Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation.

Alterations of the medullary epithelial compartment in the Aire-deficient thymus: implications for programs of thymic epithelial differentiation

An organized medullary epithelial structure in the normal thymus expresses molecules of respiratory epithelium and resembles the epithelial thymic rudiment of nude mice

An orthologous non-MHC locus in rats and mice is linked to CD4(+) and CD8(+) T-cell proportion

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells

Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation

C-kit is important for SOD1(G93A) mouse survival independent of mast cells.

Cervical thymus in the mouse

Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice

Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice

Developmental regulation of Foxp3 expression during ontogeny.

Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS.

FGFR2IIIb signaling regulates thymic epithelial differentiation

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. ⬇️

Foxp3⁺ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis.

Gain-of-function mutations in signal transducer and activator of transcription 1 (STAT1): chronic mucocutaneous candidiasis accompanied by enamel defects and delayed dental shedding.

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency.

Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

IL-2 consumption by highly activated CD8 T cells induces regulatory T-cell dysfunction in patients with hemophagocytic lymphohistiocytosis

Immunological ignorance allows long-term gene expression after perinatal recombinant adeno-associated virus-mediated gene transfer to murine airways

Irf4 Expression in Thymic Epithelium Is Critical for Thymic Regulatory T Cell Homeostasis

Lessons from thymic epithelial heterogeneity: FoxN1 and tissue-restricted gene expression by extrathymic, endodermally derived epithelium.

Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development

Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice.

MicroRNA regulation of T-cell development.

MicroRNA-29 in the adaptive immune system: setting the threshold.

Models of aire-dependent gene regulation for thymic negative selection.

Molecular control over thymic involution: from cytokines and microRNA to aging and adipose tissue

Murine Pancreatic Acinar Cell Carcinoma Growth Kinetics Are Independent of Dietary Vitamin D Deficiency or Supplementation

NOD mice, susceptible to pancreatic autoimmunity, demonstrate delayed growth of pancreatic cancer

No Effect of Dietary Aspartame or Stevia on Pancreatic Acinar Carcinoma Development, Growth, or Induced Mortality in a Murine Model

No Functional Role for microRNA-342 in a Mouse Model of Pancreatic Acinar Carcinoma.

No evidence for a role of rareCYP27B1functional variations in multiple sclerosis

Nude thymic rudiment lacking functional foxn1 resembles respiratory epithelium.

Organization of thymic medullary epithelial heterogeneity: implications for mechanisms of epithelial differentiation.

Premature thymic involution is independent of structural plasticity of the thymic stroma.

Programmed cell death-1 expression correlates with disease severity and IL-5 in chronic rhinosinusitis with nasal polyps

Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3⁺ and Foxp3⁻ T cells

Psychological comorbidity increases the risk for postinfectious IBS partly by enhanced susceptibility to develop infectious gastroenteritis

Rapamycin increases survival in ALS mice lacking mature lymphocytes.

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition

The cellular composition of the human immune system is shaped by age and cohabitation.

The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

The thymic niche does not limit development of the naturally diverse population of mouse regulatory T lymphocytes

The thymoprotective function of leptin is indirectly mediated via suppression of obesity.

Transcriptional upregulation of myelin components in spontaneous myelin basic protein-deficient mice.

miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a

miR-29a-deficiency does not modify the course of murine pancreatic acinar carcinoma.