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Lista de obras de Sean Emery

A Randomized Study of Pharmacokinetics, Efficacy, and Safety of 2 Raltegravir Plus Atazanavir Strategies in ART-Treated Adults

article

A comparison of computational models with and without genotyping for prediction of response to second-line HIV therapy.

artículo científico publicado en 2014

A comparison of three computational modelling methods for the prediction of virological response to combination HIV therapy

artículo científico publicado en 2009

A novel chemokine-receptor-5 (CCR5) blocker, SCH532706, has differential effects on CCR5+CD4+ and CCR5+CD8+ T cell numbers in chronic HIV infection

artículo científico publicado en 2010

A phase I study of the pharmacokinetics and safety of passive immunotherapy with caprine anti-HIV antibodies, (PE)HRG214, in HIV-1-infected individuals

artículo científico publicado en 2004

A randomised trial comparing genotypic and virtual phenotypic interpretation of HIV drug resistance: the CREST study

artículo científico publicado en 2006

A randomised trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients: the UK-Vanguard Study

artículo científico publicado en 2006

A randomised, open-label comparison of three highly active antiretroviral therapy regimens including two nucleoside analogues and indinavir for previously untreated HIV-1 infection: the OzCombo1 study

artículo científico publicado en 2000

A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa

artículo científico publicado en 2010

A randomized, controlled 24-week study of intermittent subcutaneous interleukin-2 in HIV-1 infected patients in Thailand

article

A randomized, placebo-controlled phase I trial of DNA prime, recombinant fowlpox virus boost prophylactic vaccine for HIV-1.

artículo científico publicado en 2006

Abacavir does not affect circulating levels of inflammatory or coagulopathic biomarkers in suppressed HIV: a randomized clinical trial

artículo científico publicado en 2010

An HIV-1 clade A/E DNA prime, recombinant fowlpox virus boost vaccine is safe, but non-immunogenic in a randomized phase I/IIa trial in Thai volunteers at low risk of HIV infection

artículo científico publicado en 2010

An objective case definition of lipodystrophy in HIV-infected adults: a case-control study

artículo científico publicado en 2003

An update to the HIV-TRePS system: the development of new computational models that do not require a genotype to predict HIV treatment outcomes

artículo científico publicado en 2013

Antiretroviral Resistance After First-Line Antiretroviral Therapy Failure in Diverse HIV-1 Subtypes in the SECOND-LINE Study

artículo científico publicado en 2016

Antiretroviral agents: Focus on Maraviroc for the Treatment of HIV-1-Infected Adults

article

Antiretroviral roll-out: the problem of second-line therapy

artículo científico publicado en 2009

Assessing site performance in the Altair study, a multinational clinical trial

artículo científico publicado en 2015

Associations between vitamin D metabolites, antiretroviral therapy and bone mineral density in people with HIV.

artículo científico publicado en 2015

Atazanavir trough plasma concentration monitoring in a cohort of HIV-1-positive individuals receiving highly active antiretroviral therapy

artículo científico publicado en 2005

Baseline HIV-1 resistance, virological outcomes, and emergent resistance in the SECOND-LINE trial: an exploratory analysis.

artículo científico publicado en 2015

Biomarkers and bacterial pneumonia risk in patients with treated HIV infection: a case-control study

artículo científico publicado en 2013

Body composition and metabolic outcomes after 96 weeks of treatment with ritonavir-boosted lopinavir plus either nucleoside or nucleotide reverse transcriptase inhibitors or raltegravir in patients with HIV with virological failure of a standard fir

artículo científico publicado en 2016

Bone mineral density in HIV participants randomized to raltegravir and lopinavir/ritonavir compared with standard second line therapy

artículo científico publicado en 2013

CD4 cell response to 3 doses of subcutaneous interleukin 2: meta-analysis of 3 Vanguard studies

artículo científico publicado en 2004

Cerebrospinal fluid exposure of efavirenz and its major metabolites when dosed at 400 mg and 600 mg once daily: a randomized controlled trial

artículo científico publicado en 2014

Changes in bone turnover and bone loss in HIV-infected patients changing treatment to tenofovir-emtricitabine or abacavir-lamivudine

artículo científico publicado en 2012

Changes in plasma lipidome following initiation of antiretroviral therapy

artículo científico publicado en 2018

Chemokine receptor genotype and response to interleukin-2 therapy in HIV-1-infected individuals

article

Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study

artículo científico publicado en 2015

Clinical trials of antiretroviral therapy in developing countries

scientific article published on 01 February 2000

Combined analysis of two-year follow-up from two open-label randomized trials comparing efficacy of three nucleoside reverse transcriptase inhibitor backbones for previously untreated HIV-1 infection: OzCombo 1 and 2.

artículo científico publicado en 2003

Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naïve HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study

artículo científico publicado en 2015

Computational models as predictors of HIV treatment outcomes for the Phidisa cohort in South Africa.

artículo científico publicado en 2016

Considerations in the rationale, design and methods of the Strategic Timing of AntiRetroviral Treatment (START) study

artículo científico publicado en 2012

Demographic and HIV-specific characteristics of participants enrolled in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial

artículo científico publicado en 2015

Determination of clinically relevant cutoffs for HIV-1 phenotypic resistance estimates through a combined analysis of clinical trial and cohort data

artículo científico publicado en 2008

Differences in the direction of change of cerebral function parameters are evident over three years in HIV-infected individuals electively commencing initial cART.

artículo científico publicado en 2015

Disease Progression and Fatal Outcomes in HIV‐Infected Patients during Interruption of Antiretroviral Treatment

article

Does choice of combination antiretroviral therapy (cART) alter changes in cerebral function testing after 48 weeks in treatment-naive, HIV-1-infected individuals commencing cART? A randomized, controlled study.

artículo científico publicado en 2010

Dynamics of cognitive change in HIV-infected individuals commencing three different initial antiretroviral regimens: a randomized, controlled study

article

Early antiretroviral therapy with raltegravir generates sustained reductions in HIV reservoirs but not lower T-cell activation levels

artículo científico publicado en 2015

Efavirenz plasma concentrations did not predict cessation of therapy due to neuropsychiatric symptoms in a large randomized trial

artículo científico publicado en 2009

Efavirenz versus Boosted Atazanavir or Zidovudine and Abacavir in Antiretroviral Treatment–Naive, HIV‐Infected Subjects: Week 48 Data from the Altair Study ⬇️

artículo científico publicado el 1 de octubre de 2010

Effect of nucleoside reverse transcriptase inhibitors on CD4 T-cell recovery in HIV-1-infected individuals receiving long-term fully suppressive combination antiretroviral therapy.

artículo científico publicado en 2008

Effect of rosiglitazone on peroxisome proliferator-activated receptor gamma gene expression in human adipose tissue is limited by antiretroviral drug-induced mitochondrial dysfunction

artículo científico publicado en 2008

Effects of IL-2 therapy in asymptomatic HIV-infected individuals on proliferative responses to mitogens, recall antigens and HIV-related antigens

artículo científico publicado en 1998

Effects of alpha-tocopherol on carbon tetrachloride metabolism in rat liver microsomes.

artículo científico publicado en 1987

Efficacy and safety of efavirenz 400 mg daily versus 600 mg daily: 96-week data from the randomised, double-blind, placebo-controlled, non-inferiority ENCORE1 study

artículo científico publicado en 2015

Evaluation in macaques of HIV-1 DNA vaccines containing primate CpG motifs and fowlpoxvirus vaccines co-expressing IFN? or IL-12

article

Evaluation of ultrasound for assessing facial lipoatrophy in a randomized, placebo-controlled trial

artículo científico publicado en 2005

Evolution of CD4+ T cell count in HIV-1-infected adults receiving antiretroviral therapy with sustained long-term virological suppression

artículo científico publicado en 2009

HIV DNA subspecies persist in both activated and resting memory CD4+ T cells during antiretroviral therapy

artículo científico publicado en 2014

HIV disease progression in a patient cohort treated via a clinical research network in a resource limited setting

article

HIV lipodystrophy in participants randomised to lopinavir/ritonavir (LPV/r) +2-3 nucleoside/nucleotide reverse transcriptase inhibitors (N(t)RTI) or LPV/r + raltegravir as second-line antiretroviral therapy

artículo científico publicado en 2013

HLA alleles association with changes in bone mineral density in HIV-1-infected adults changing treatment to tenofovir-emtricitabine or abacavir-lamivudine

artículo científico publicado en 2014

High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40).

artículo científico publicado en 2009

Hip structural parameters over 96 weeks in HIV-infected adults switching treatment to tenofovir-emtricitabine or abacavir-lamivudine

artículo científico publicado en 2014

Immune reconstitution in HIV infection

article

Immune-based therapies in HIV infection

article

Immunodeficiency and the risk of serious clinical endpoints in a well studied cohort of treated HIV-infected patients

artículo científico publicado en 2010

Immunomodulators as adjunctive therapy for HIV-1 infection

article

Impact of lamivudine on HIV and hepatitis B virus-related outcomes in HIV/hepatitis B virus individuals in a randomized clinical trial of antiretroviral therapy in southern Africa

artículo científico publicado en 2011

Impact of treatment with raltegravir during primary or chronic HIV infection on RNA decay characteristics and the HIV viral reservoir

artículo científico publicado en 2011

Improved quality of life with immediate versus deferred initiation of antiretroviral therapy in early asymptomatic HIV infection

artículo científico publicado en 2017

In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA.

artículo científico publicado en 2005

Inferior clinical outcome of the CD4+ cell count-guided antiretroviral treatment interruption strategy in the SMART study: role of CD4+ Cell counts and HIV RNA levels during follow-up

artículo científico publicado en 2008

Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection

artículo científico publicado en 2015

Integrated HIV DNA accumulates prior to treatment while episomal HIV DNA records ongoing transmission afterwards

artículo científico publicado en 2012

Intensification of antiretroviral therapy with raltegravir or addition of hyperimmune bovine colostrum in HIV-infected patients with suboptimal CD4+ T-cell response: a randomized controlled trial

artículo científico publicado en 2011

Lipid profiles in HIV-infected adults receiving atazanavir and atazanavir/ritonavir: systematic review and meta-analysis of randomized controlled trials

artículo científico publicado en 2010

Lipodystrophy following antiretroviral therapy of primary HIV infection

article

Low-dose versus standard-dose ritonavir-boosted atazanavir in virologically suppressed Thai adults with HIV (LASA): a randomised, open-label, non-inferiority trial

artículo científico publicado en 2016

Major clinical outcomes in antiretroviral therapy (ART)-naive participants and in those not receiving ART at baseline in the SMART study

artículo científico publicado en 2008

Maraviroc, as a Switch Option, in HIV-1-infected Individuals With Stable, Well-controlled HIV Replication and R5-tropic Virus on Their First Nucleoside/Nucleotide Reverse Transcriptase Inhibitor Plus Ritonavir-boosted Protease Inhibitor Regimen: Wee

artículo científico publicado en 2016

Metabolic disorders and cardiovascular consequences of  HIV infection and antiretroviral  therapy

artículo científico

Minor changes in calculated creatinine clearance and anion-gap are associated with tenofovir disoproxil fumarate-containing highly active antiretroviral therapy

artículo científico publicado en 2006

Nadir CD4 count and monthly income predict cervical squamous cell abnormalities in HIV-positive women in a resource-limited setting

artículo científico publicado en 2008

No effect of rosiglitazone for treatment of HIV-1 lipoatrophy: randomised, double-blind, placebo-controlled trial.

artículo científico publicado en 2004

Pharmacokinetic and Pharmacodynamic Comparison of Once-Daily Efavirenz (400 mg vs. 600 mg) in Treatment-Naïve HIV-Infected Patients: Results of the ENCORE1 Study

artículo científico publicado en 2015

Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study

artículo científico publicado en 2011

Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers

artículo científico publicado en 2010

Plasma levels of soluble CD14 independently predict mortality in HIV infection

artículo científico publicado en 2011

Poly-l-lactic acid for HIV-1 facial lipoatrophy: 48-week follow-up.

artículo científico publicado en 2009

Pre-therapy inflammation and coagulation activation and long-term CD4 count responses to the initiation of antiretroviral therapy

artículo científico publicado en 2015

Predicting the potential benefits of early initiation of ART: time to do a trial to find out

Predictors of bacterial pneumonia in Evaluation of Subcutaneous Interleukin-2 in a Randomized International Trial (ESPRIT).

artículo científico publicado en 2010

Predictors of clinical progression in HIV-1-infected adults initiating combination antiretroviral therapy with advanced disease in the Asia-Pacific region: results from the TREAT Asia HIV observational database

artículo científico publicado en 2013

Predictors of limb fat gain in HIV positive patients following a change to tenofovir-emtricitabine or abacavir-lamivudine

artículo científico publicado en 2011

Project Phidisa: development of clinical research capacity within the South African National Defence Force

artículo científico publicado en 2007

Pulmonary effects of immediate versus deferred antiretroviral therapy in HIV-positive individuals: a nested substudy within the multicentre, international, randomised, controlled Strategic Timing of Antiretroviral Treatment (START) trial

artículo científico publicado en 2016

Raltegravir non-inferior to nucleoside based regimens in second-line therapy with lopinavir/ritonavir over 96 weeks: a randomised open label study for the treatment of HIV-1 infection

artículo científico publicado en 2015

Raltegravir: a new choice in HIV and new chances for research

artículo científico publicado en 2009

Reply

scientific article published in 2001

Reply to "Issues on results of the external quality assessment for proviral DNA testing of HIV-1 Tropism in the Maraviroc Switch collaborative study".

artículo científico publicado en 2013

Results of external quality assessment for proviral DNA testing of HIV tropism in the Maraviroc Switch collaborative study

artículo científico publicado en 2013

Safety and immunogenicity of UBI HIV-1MN octameric V3 peptide vaccine administered by subcutaneous injection.

artículo científico publicado en 1997

Selective exclusion of treatment arms in multi-arm randomized clinical trials

Short Communication: Nonnucleoside Reverse Transcriptase Inhibitor Fold Change or Plasma Concentration as a Predictor of Virological Response over 48 Weeks in Highly Treatment Experienced HIV-Positive Individuals

article

Short communication: HIV blips while on antiretroviral therapy can indicate consistently detectable viral levels due to assay underreporting

artículo científico publicado en 2013

Simplification of antiretroviral therapy with tenofovir-emtricitabine or abacavir-Lamivudine: a randomized, 96-week trial

artículo científico publicado en 2009

Soluble biomarkers and morbidity and mortality among people infected with HIV: summary of published reports from 1997 to 2010

artículo científico publicado en 2010

Substantial improvements in performance indicators achieved in a peripheral blood mononuclear cell cryopreservation quality assurance program using single donor samples

artículo científico publicado en 2006

The Safety, Efficacy, and Pharmacokinetic Profile of a Switch in Antiretroviral Therapy to Saquinavir, Ritonavir, and Atazanavir Alone for 48 Weeks and a Switch in the Saquinavir Formulation

scientific article published in 2007

The development of an expert system to predict virological response to HIV therapy as part of an online treatment support tool

artículo científico publicado en 2011

The effect of cimetidine and ranitidine on paracetamol glucuronidation and sulphation in cultured rat hepatocytes

artículo científico publicado en 1985

The evaluation of subcutaneous proleukin (interleukin-2) in a randomized international trial: rationale, design, and methods of ESPRIT.

artículo científico publicado en 2002

The impact of registration of clinical trials units: the UK experience

artículo científico publicado en 2014

The influence of HLA supertype on thymidine analogue associated with low peripheral fat in HIV.

artículo científico publicado en 2012

The normalized inhibitory quotient of boosted protease inhibitors is predictive of viral load response in treatment-experienced HIV-1-infected individuals

artículo científico publicado en 2005

The potential cost and benefits of raltegravir in simplified second-line therapy among HIV infected patients in Nigeria and South Africa

artículo científico publicado en 2013

The search for an HIV cure: tackling latent infection

artículo científico

Therapeutic Strategies for HIV Infection — Time to Think Hard

article

Therapeutic vaccination against HIV: current progress and future possibilities

artículo científico publicado en 2006

Three-year durability of dual-nucleoside versus triple-nucleoside therapy in a Thai population with HIV infection

artículo científico publicado en 2004

Two patterns of cerebral metabolite abnormalities are detected on proton magnetic resonance spectroscopy in HIV-infected subjects commencing antiretroviral therapy.

artículo científico publicado en 2012

Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a ‘high-affinity’ FcγRIIa genotype

article

Viral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimen

artículo científico publicado en 2008

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