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Lista de obras de Klaus H Kaestner

5-hydroxymethylcytosine represses the activity of enhancers in embryonic stem cells: a new epigenetic signature for gene regulation

artículo científico publicado en 2014

A High-Content Screen Identifies MicroRNAs That Regulate Liver Repopulation After Injury in Mice

scientific article published on 20 November 2019

CREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse β-cells

artículo científico publicado en 2014

Collapse of the hepatic gene regulatory network in the absence of FoxA factors

scientific article published on 19 June 2020

Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform.

artículo científico publicado en 2017

Emerging diverse roles of telocytes

artículo científico publicado en 2019

Epigenetic regulation of intestinal stem cells by Tet1-mediated DNA hydroxymethylation.

artículo científico publicado en 2016

Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally

artículo científico publicado en 2018

Fox transcription factors: from development to disease

artículo científico publicado en 2016

FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer

artículo científico publicado en 2018

Genetic activation of α-cell glucokinase in mice causes enhanced glucose-suppression of glucagon secretion during normal and diabetic states

artículo científico publicado en 2021

Insights From the Crypt: Regionalization, Adaptation, and Renewal of the Intestinal Epithelium

artículo científico publicado en 2017

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

artículo científico publicado en 2001

Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes

artículo científico

LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.

artículo científico publicado en 2016

Metabolic memory of ß-cells controls insulin secretion and is mediated by CaMKII.

artículo científico publicado en 2014

NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP)

artículo científico publicado en 2019

Organisation of the human pancreas in health and in diabetes

artículo científico publicado en 2020

Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice.

artículo científico publicado en 2018

Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry

artículo científico publicado en 2021

Sleeve Gastrectomy Improves Glycemia Independent of Weight Loss by Restoring Hepatic Insulin Sensitivity

artículo científico publicado en 2018

TRAP-seq identifies cystine/glutamate antiporteras a driver of recovery from liver injury.

artículo científico publicado en 2018

The 'de novo' DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium.

artículo científico publicado en 2016

The Dysregulation of the - Locus in Islets From Patients With Type 2 Diabetes Is Mimicked by Targeted Epimutation of Its Promoter With TALE-DNMT Constructs

scientific article published on 03 July 2018

The RNA polymerase III subunit Polr3b is required for the maintenance of small intestinal crypts in mice

artículo científico publicado en 2016

β-Cells are not uniform after all-Novel insights into molecular heterogeneity of insulin-secreting cells

artículo científico publicado en 2017