Lista de obras - Marc Poirot - Dominio Público Uruguay

5,6-Epoxy-cholesterols contribute to the anticancer pharmacology of tamoxifen in breast cancer cells

artículo científico publicado en 2013

A fast UPLC-HILIC method for an accurate quantiﬁcation of dendrogenin A in human tissues

artículo científico publicado en 2019

Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors.

artículo científico publicado en 2010

Bryonolic Acid Blocks Cancer Cell Clonogenicity and Invasiveness through the Inhibition of Fatty Acid: Cholesteryl Ester Formation

artículo científico publicado en 2018

Cancer. Cholesterol and cancer, in the balance

artículo científico publicado en 2014

Characterization of a benzyl-phenoxy-ethanamine binding protein in Trypanosoma equiperdum and the possible relation between binding affinity and trypanocidal activity.

artículo científico publicado en 1993

Characterization of the membranous antiestrogen binding protein: I. Partial purification of the protein in its active state

artículo científico publicado en 1994

Characterization of the membranous antiestrogen binding protein: II. Purification to homogeneity

scientific article published on 01 January 1994

Chemistry, biochemistry, metabolic fate and mechanism of action of 6-oxo-cholestan-3β,5α-diol (OCDO), a tumor promoter and cholesterol metabolite.

artículo científico publicado en 2018

Cholesterol epoxide hydrolase and cancer ⬇️

artículo científico publicado el 21 de agosto de 2012

Cholesterol metabolism and cancer: the good, the bad and the ugly ⬇️

artículo científico publicado el 26 de octubre de 2012

Cholesterol metabolism and resistance to tamoxifen.

artículo científico

Cholesterol-5,6-epoxides: chemistry, biochemistry, metabolic fate and cancer.

artículo científico

Contrasting effects of prenyltransferase inhibitors on estrogen-dependent cell cycle progression and estrogen receptor-mediated transcriptional activity in MCF-7 cells.

artículo científico publicado en 2003

Cytosolic type II estrogen binding site in rat uterus: specific photolabeling with estrone

artículo científico publicado en 1992

Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia

scientific article published on 12 October 2020

Dendrogenin A drives LXR to trigger lethal autophagy in cancers.

artículo científico publicado en 2017

Development of a new radioligand for cholecystokinin receptor subtype 2 scintigraphy: from molecular modeling to in vivo evaluation.

artículo científico publicado en 2010

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins.

artículo científico publicado en 2010

Exosomes as intercellular signalosomes and pharmacological effectors.

artículo científico publicado en 2011

Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies.

artículo científico publicado en 2013

Extracellular vesicles: lipids as key components of their biogenesis and functions

scientific article published on 15 May 2018

Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways.

artículo científico publicado en 2005

Flavonoids differentially modulate liver X receptors activity-Structure-function relationship analysis

scientific article published on 05 April 2019

From tamoxifen to dendrogenin A: The discovery of a mammalian tumor suppressor and cholesterol metabolite.

artículo científico publicado en 2016

Further evidence for a biological role of anti-estrogen-binding sites in mediating the growth inhibitory action of diphenylmethane derivatives

artículo científico publicado en 1988

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

HPLC Analysis and Skin Whitening Effects of Umbelliprenin-containing Extracts of , , and

artículo científico publicado en 2019

High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor.

artículo científico publicado en 2003

Human monocyte recognition of adenosine-based cyclic dinucleotides unveils the A2a Gαs protein-coupled receptor tonic inhibition of mitochondrially induced cell death

artículo científico publicado en 2014

Identification of a new stilbene-derived inducer of paraoxonase 1 and ligand of the Aryl hydrocarbon Receptor.

artículo científico publicado en 2011

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

artículo científico publicado en 2017

Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies

artículo científico publicado en 2003

Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands ⬇️

artículo científico publicado el 27 de mayo de 2011

Improved realism of hybrid mouse models may not be sufficient to generate reference dosimetric data ⬇️

artículo científico publicado el 1 de mayo de 2013

Improvement of 5,6α-epoxycholesterol, 5,6β-epoxycholesterol, cholestane-3β,5α,6β-triol and 6-oxo-cholestan-3β,5α-diol recovery for quantification by GC/MS.

artículo científico publicado en 2017

Improving the efficacy of hormone therapy in breast cancer: The role of cholesterol metabolism in SERM-mediated autophagy, cell differentiation and death

artículo científico publicado en 2017

Insights into the cholecystokinin 2 receptor binding site and processes of activation

scientific article published on 22 September 2006

Insulin and estrogen receptor ligand influence the FGF-2 activities in MCF-7 breast cancer cells

artículo científico publicado en 2003

Ligand-dependent transcriptional induction of lethal autophagy: a new perspective for cancer treatment

artículo científico publicado en 2018

Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism

artículo científico publicado en 2009

MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy.

artículo científico publicado en 2012

Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism.

artículo científico publicado en 2008

Microsomal epoxide hydrolase of rat liver is a subunit of theanti-oestrogen-binding site ⬇️

artículo científico publicado el 15 de agosto de 1998

Molecular characterization of the microsomal tamoxifen binding site

artículo científico publicado en 2004

Natural and semisynthetic oxyprenylated aromatic compounds as stimulators or inhibitors of melanogenesis

artículo científico publicado en 2019

One step synthesis of 6-oxo-cholestan-3β,5α-diol

artículo científico publicado en 2014

Oxysterols and related sterols: implications in pharmacology and pathophysiology

artículo científico publicado en 2013

Oxysterols: An expanding family of structurally diversified bioactive steroids

scientific article published on 31 July 2019

Progesterone and a phospholipase inhibitor increase the endosomal bis(monoacylglycero)phosphate content and block HIV viral particle intercellular transmission

artículo científico publicado en 2013

Quantitative analysis of the tumor suppressor dendrogenin A using liquid chromatography tandem mass spectrometry.

artículo científico publicado en 2017

Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion

artículo científico publicado en 2009

Sterol metabolism and cancer

artículo científico publicado en 2022

Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor

artículo científico publicado en 1999

Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators.

artículo científico publicado en 2005

Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases.

artículo científico publicado en 2009

Synthesis, characterization and in vitro evaluation of new oxorhenium- and oxotechnetium-CCK4 derivatives as molecular imaging agents for CCK2-receptor targeting.

artículo científico publicado en 2009

Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells.

artículo científico publicado en 2003

Technical note: Hapten synthesis, antibody production and development of an enzyme-linked immunosorbent assay for detection of the natural steroidal alkaloid Dendrogenin A.

artículo científico publicado en 2012

The 5,6-epoxycholesterol metabolic pathway in breast cancer: emergence of new pharmacological targets

artículo científico publicado en 2020

The Effects of Cholesterol-Derived Oncometabolites on Nuclear Receptor Function in Cancer

scientific article published on 17 August 2018

The anti-proliferative properties of 4-benzylphenoxy ethanamine derivatives are mediated by the anti-estrogen binding site (ABS), whereas the anti-estrogenic effects of trifluopromazine are not.

artículo científico publicado en 1990

The cholesterol-derived metabolite dendrogenin A functionally reprograms breast adenocarcinoma and undifferentiated thyroid cancer cells

scientific article published on 03 June 2019

The novel steroidal alkaloids dendrogenin A and B promote proliferation of adult neural stem cells

artículo científico publicado en 2014

The prototypical inhibitor of cholesterol esterification, Sah 58-035 [3-[decyldimethylsilyl]-n-[2-(4-methylphenyl)-1-phenylethyl]propanamide], is an agonist of estrogen receptors.

artículo científico publicado en 2006

The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers.

artículo científico publicado en 2018

When cholesterol meets histamine, it gives rise to dendrogenin A: a tumour suppressor metabolite

artículo científico publicado en 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Marc Poirot

5,6-Epoxy-cholesterols contribute to the anticancer pharmacology of tamoxifen in breast cancer cells

A fast UPLC-HILIC method for an accurate quantiﬁcation of dendrogenin A in human tissues

Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors.

Bryonolic Acid Blocks Cancer Cell Clonogenicity and Invasiveness through the Inhibition of Fatty Acid: Cholesteryl Ester Formation

Cancer. Cholesterol and cancer, in the balance

Characterization of a benzyl-phenoxy-ethanamine binding protein in Trypanosoma equiperdum and the possible relation between binding affinity and trypanocidal activity.

Characterization of the membranous antiestrogen binding protein: I. Partial purification of the protein in its active state

Characterization of the membranous antiestrogen binding protein: II. Purification to homogeneity

Chemistry, biochemistry, metabolic fate and mechanism of action of 6-oxo-cholestan-3β,5α-diol (OCDO), a tumor promoter and cholesterol metabolite.

Cholesterol epoxide hydrolase and cancer ⬇️

Cholesterol metabolism and cancer: the good, the bad and the ugly ⬇️

Cholesterol metabolism and resistance to tamoxifen.

Cholesterol-5,6-epoxides: chemistry, biochemistry, metabolic fate and cancer.

Contrasting effects of prenyltransferase inhibitors on estrogen-dependent cell cycle progression and estrogen receptor-mediated transcriptional activity in MCF-7 cells.

Cytosolic type II estrogen binding site in rat uterus: specific photolabeling with estrone

Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia

Dendrogenin A drives LXR to trigger lethal autophagy in cancers.

Development of a new radioligand for cholecystokinin receptor subtype 2 scintigraphy: from molecular modeling to in vivo evaluation.

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins.

Exosomes as intercellular signalosomes and pharmacological effectors.

Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies.

Extracellular vesicles: lipids as key components of their biogenesis and functions

Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways.

Flavonoids differentially modulate liver X receptors activity-Structure-function relationship analysis

From tamoxifen to dendrogenin A: The discovery of a mammalian tumor suppressor and cholesterol metabolite.

Further evidence for a biological role of anti-estrogen-binding sites in mediating the growth inhibitory action of diphenylmethane derivatives

Guidelines for the use and interpretation of assays for monitoring autophagy

HPLC Analysis and Skin Whitening Effects of Umbelliprenin-containing Extracts of , , and

High tumorigenic potential of a constitutively active mutant of the cholecystokinin 2 receptor.

Human monocyte recognition of adenosine-based cyclic dinucleotides unveils the A2a Gαs protein-coupled receptor tonic inhibition of mitochondrially induced cell death

Identification of a new stilbene-derived inducer of paraoxonase 1 and ligand of the Aryl hydrocarbon Receptor.

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies

Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands ⬇️

Improved realism of hybrid mouse models may not be sufficient to generate reference dosimetric data ⬇️

Improvement of 5,6α-epoxycholesterol, 5,6β-epoxycholesterol, cholestane-3β,5α,6β-triol and 6-oxo-cholestan-3β,5α-diol recovery for quantification by GC/MS.

Improving the efficacy of hormone therapy in breast cancer: The role of cholesterol metabolism in SERM-mediated autophagy, cell differentiation and death

Insights into the cholecystokinin 2 receptor binding site and processes of activation

Insulin and estrogen receptor ligand influence the FGF-2 activities in MCF-7 breast cancer cells

Ligand-dependent transcriptional induction of lethal autophagy: a new perspective for cancer treatment

Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism

MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy.

Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism.

Microsomal epoxide hydrolase of rat liver is a subunit of theanti-oestrogen-binding site ⬇️

Molecular characterization of the microsomal tamoxifen binding site

Natural and semisynthetic oxyprenylated aromatic compounds as stimulators or inhibitors of melanogenesis

One step synthesis of 6-oxo-cholestan-3β,5α-diol

Oxysterols and related sterols: implications in pharmacology and pathophysiology

Oxysterols: An expanding family of structurally diversified bioactive steroids

Progesterone and a phospholipase inhibitor increase the endosomal bis(monoacylglycero)phosphate content and block HIV viral particle intercellular transmission

Quantitative analysis of the tumor suppressor dendrogenin A using liquid chromatography tandem mass spectrometry.

Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion

Sterol metabolism and cancer

Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor

Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators.

Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases.

Synthesis, characterization and in vitro evaluation of new oxorhenium- and oxotechnetium-CCK4 derivatives as molecular imaging agents for CCK2-receptor targeting.

Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells.

Technical note: Hapten synthesis, antibody production and development of an enzyme-linked immunosorbent assay for detection of the natural steroidal alkaloid Dendrogenin A.

The 5,6-epoxycholesterol metabolic pathway in breast cancer: emergence of new pharmacological targets

The Effects of Cholesterol-Derived Oncometabolites on Nuclear Receptor Function in Cancer

The anti-proliferative properties of 4-benzylphenoxy ethanamine derivatives are mediated by the anti-estrogen binding site (ABS), whereas the anti-estrogenic effects of trifluopromazine are not.

The cholesterol-derived metabolite dendrogenin A functionally reprograms breast adenocarcinoma and undifferentiated thyroid cancer cells

The novel steroidal alkaloids dendrogenin A and B promote proliferation of adult neural stem cells

The prototypical inhibitor of cholesterol esterification, Sah 58-035 [3-[decyldimethylsilyl]-n-[2-(4-methylphenyl)-1-phenylethyl]propanamide], is an agonist of estrogen receptors.

The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers.

When cholesterol meets histamine, it gives rise to dendrogenin A: a tumour suppressor metabolite

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)