Lista de obras - Sally J. Dawson - Dominio Público Uruguay

A Single Amino Acid Change Converts an Inhibitory Transcription Factor into an Activator

artículo científico publicado en 1996

A functional and genetic analysis of SOD2 promoter variants and their contribution to age-related hearing loss

artículo científico publicado en 2013

A single residue within the homeodomain of the Brn-3 POU family transcription factors determines whether they activate or repress the SNAP-25 promoter ⬇️

artículo científico publicado el 27 de mayo de 1997

Activation of fibroblast procollagen alpha 1(I) transcription by mechanical strain is transforming growth factor-beta-dependent and involves increased binding of CCAAT-binding factor (CBF/NF-Y) at the proximal promoter

scientific journal article

Activation of the iNOS gene promoter by Brn-3 POU family transcription factors is dependent upon the octamer motif in the promoter

artículo científico publicado en 1998

Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles.

artículo científico publicado en 1998

Age-Related Hearing Loss

artículo científico publicado en 2019

Aminoglycoside antibiotics cochleotoxicity in paediatric cystic fibrosis (CF) patients: A study using extended high-frequency audiometry and distortion product otoacoustic emissions

artículo científico publicado en 2011

Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity

artículo científico publicado en 2004

Caprin-1 is a target of the deafness gene Pou4f3 and is recruited to stress granules in cochlear hair cells in response to ototoxic damage

artículo científico publicado en 2011

Clarin-2 is essential for hearing by maintaining stereocilia integrity and function

scientific article published on 26 August 2019

Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor

artículo científico publicado en 1997

Correction: Self-reported hearing loss questions provide a good measure for genetic studies: a polygenic risk score analysis from UK Biobank

scientific article published in 2021

Differential regulation of genes encoding synaptic proteins by members of the Brn-3 subfamily of POU transcription factors

artículo científico publicado en 1996

Differential regulation of genes encoding synaptic proteins by the Oct-2 transcription factor

artículo científico publicado en 1997

Differential regulation of the two neuronal nitric-oxide synthase gene promoters by the Oct-2 transcription factor

artículo científico publicado en 1996

Direct evidence that the POU family transcription factor Oct-2 represses the cellular tyrosine hydroxylase gene in neuronal cells

artículo científico publicado en 1995

Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear.

artículo científico publicado en 2017

Drug-induced Stress Granule Formation Protects Sensory Hair Cells in Mouse Cochlear Explants During Ototoxicity

scientific article published on 29 August 2019

Estrogen-related receptor gamma and hearing function: evidence of a role in humans and mice

artículo científico publicado en 2013

Evidence of distinct RELN and TGFB1 genetic associations in familial and non-familial otosclerosis in a British population.

artículo científico publicado en 2018

Functional role of position 22 in the homeodomain of Brn-3 transcription factors ⬇️

artículo científico publicado el 13 de julio de 1998

GWAS Identifies 44 Independent Associated Genomic Loci for Self-Reported Adult Hearing Difficulty in UK Biobank

scientific article published on 26 September 2019

Genetic variation at the plasminogen activator inhibitor-1 locus is associated with altered levels of plasma plasminogen activator inhibitor-1 activity ⬇️

artículo científico publicado el 1 de enero de 1991

Genome-wide association analysis on normal hearing function identifies PCDH20 and SLC28A3 as candidates for hearing function and loss

artículo científico publicado en 2015

Hearing difficulty is linked to Alzheimer’s disease by common genetic vulnerability, not shared genetic architecture

artículo científico publicado en 2021

High-frequency audiometry reveals high prevalence of aminoglycoside ototoxicity in children with cystic fibrosis

artículo científico publicado en 2014

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

article

Mutations and altered expression of SERPINF1 in patients with familial otosclerosis

artículo científico publicado en 2016

Normal hearing in a child with the m.1555A>G mutation despite repeated exposure to aminoglycosides. Has the penetrance of this pharmacogenetic interaction been overestimated?

artículo científico publicado en 2014

Possibilities of DNA analysis for the detection of predisposition to thrombotic disease

artículo científico publicado el 4 de diciembre de 1992

Regulation of the orphan nuclear receptor Nr2f2 by the DFNA15 deafness gene Pou4f3.

artículo científico publicado en 2014

S1PR2 variants associated with auditory function in humans and endocochlear potential decline in mouse

artículo científico publicado en 2016

Self-reported hearing loss questions provide a good measure for genetic studies: a polygenic risk score analysis from UK Biobank

artículo científico publicado en 2020

The DFNA15 deafness mutation affects POU4F3 protein stability, localization, and transcriptional activity

artículo científico publicado en 2003

The Epidemiology of Otosclerosis in a British Cohort

artículo científico publicado en 2019

The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression ⬇️

artículo científico publicado el 15 de septiembre de 1998

The ability of the inhibitory domain of the POU family transcription factor Oct-2 to interfere with promoter activation by different classes of activation domains is dependent upon the nature of the basal promoter elements

artículo científico publicado en 1996

The different inhibitory domains of the Oct‐2 transcription factor have distinct functional activities ⬇️

artículo científico publicado el 20 de octubre de 1997

The future role of genetic screening to detect newborns at risk of childhood-onset hearing loss

artículo científico publicado en 2013

The mouse as a model for age-related hearing loss - a mini-review.

artículo científico publicado en 2014

The status of PAI-1 as a risk factor for arterial and thrombotic disease: a review

artículo científico publicado el 1 de agosto de 1992

Transcriptional regulation by Barhl1 and Brn-3c in organ-of-Corti-derived cell lines.

artículo científico publicado en 2005

Whole exome sequencing in adult-onset hearing loss reveals a high load of predicted pathogenic variants in known deafness-associated genes and identifies new candidate genes

article

Lista de obras de Sally J. Dawson

A Single Amino Acid Change Converts an Inhibitory Transcription Factor into an Activator

A functional and genetic analysis of SOD2 promoter variants and their contribution to age-related hearing loss

A single residue within the homeodomain of the Brn-3 POU family transcription factors determines whether they activate or repress the SNAP-25 promoter ⬇️

Activation of fibroblast procollagen alpha 1(I) transcription by mechanical strain is transforming growth factor-beta-dependent and involves increased binding of CCAAT-binding factor (CBF/NF-Y) at the proximal promoter

Activation of the iNOS gene promoter by Brn-3 POU family transcription factors is dependent upon the octamer motif in the promoter

Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles.

Age-Related Hearing Loss

Aminoglycoside antibiotics cochleotoxicity in paediatric cystic fibrosis (CF) patients: A study using extended high-frequency audiometry and distortion product otoacoustic emissions

Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity

Caprin-1 is a target of the deafness gene Pou4f3 and is recruited to stress granules in cochlear hair cells in response to ototoxic damage

Clarin-2 is essential for hearing by maintaining stereocilia integrity and function

Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor

Correction: Self-reported hearing loss questions provide a good measure for genetic studies: a polygenic risk score analysis from UK Biobank

Differential regulation of genes encoding synaptic proteins by members of the Brn-3 subfamily of POU transcription factors

Differential regulation of genes encoding synaptic proteins by the Oct-2 transcription factor

Differential regulation of the two neuronal nitric-oxide synthase gene promoters by the Oct-2 transcription factor

Direct evidence that the POU family transcription factor Oct-2 represses the cellular tyrosine hydroxylase gene in neuronal cells

Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear.

Drug-induced Stress Granule Formation Protects Sensory Hair Cells in Mouse Cochlear Explants During Ototoxicity

Estrogen-related receptor gamma and hearing function: evidence of a role in humans and mice

Evidence of distinct RELN and TGFB1 genetic associations in familial and non-familial otosclerosis in a British population.

Functional role of position 22 in the homeodomain of Brn-3 transcription factors ⬇️

GWAS Identifies 44 Independent Associated Genomic Loci for Self-Reported Adult Hearing Difficulty in UK Biobank

Genetic variation at the plasminogen activator inhibitor-1 locus is associated with altered levels of plasma plasminogen activator inhibitor-1 activity ⬇️

Genome-wide association analysis on normal hearing function identifies PCDH20 and SLC28A3 as candidates for hearing function and loss

Hearing difficulty is linked to Alzheimer’s disease by common genetic vulnerability, not shared genetic architecture

High-frequency audiometry reveals high prevalence of aminoglycoside ototoxicity in children with cystic fibrosis

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Mutations and altered expression of SERPINF1 in patients with familial otosclerosis

Normal hearing in a child with the m.1555A>G mutation despite repeated exposure to aminoglycosides. Has the penetrance of this pharmacogenetic interaction been overestimated?

Possibilities of DNA analysis for the detection of predisposition to thrombotic disease

Regulation of the orphan nuclear receptor Nr2f2 by the DFNA15 deafness gene Pou4f3.

S1PR2 variants associated with auditory function in humans and endocochlear potential decline in mouse

Self-reported hearing loss questions provide a good measure for genetic studies: a polygenic risk score analysis from UK Biobank

The DFNA15 deafness mutation affects POU4F3 protein stability, localization, and transcriptional activity

The Epidemiology of Otosclerosis in a British Cohort

The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression ⬇️

The ability of the inhibitory domain of the POU family transcription factor Oct-2 to interfere with promoter activation by different classes of activation domains is dependent upon the nature of the basal promoter elements

The different inhibitory domains of the Oct‐2 transcription factor have distinct functional activities ⬇️

The future role of genetic screening to detect newborns at risk of childhood-onset hearing loss

The mouse as a model for age-related hearing loss - a mini-review.

The status of PAI-1 as a risk factor for arterial and thrombotic disease: a review

Transcriptional regulation by Barhl1 and Brn-3c in organ-of-Corti-derived cell lines.

Whole exome sequencing in adult-onset hearing loss reveals a high load of predicted pathogenic variants in known deafness-associated genes and identifies new candidate genes