Lista de obras - Francesca Fallarino - Dominio Público Uruguay

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

artículo científico publicado en 2021

A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression

artículo científico publicado en 2012

A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells

artículo científico publicado en 2017

A crucial role for tryptophan catabolism at the host/Candida albicans interface.

artículo científico publicado en 2005

A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice

artículo científico publicado en 2003

Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers

artículo científico publicado en 2015

AhR-Mediated, Non-Genomic Modulation of IDO1 Function

artículo científico publicado en 2014

AhR: far more than an environmental sensor

artículo científico publicado en 2014

Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells

artículo científico publicado en 2015

Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

artículo científico publicado en 2018

Antigen-specific regression of established tumors induced by active immunization with irradiated IL-12- but not B7-1-transfected tumor cells ⬇️

artículo científico publicado el 1 de septiembre de 1997

Aryl Hydrocarbon Receptor-Dependent Pathways in Immune Regulation.

artículo científico publicado en 2016

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

artículo científico publicado en 2014

Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype

artículo científico publicado en 2015

B7-1 Engagement of Cytotoxic T Lymphocyte Antigen 4 Inhibits T Cell Activation in the Absence of CD28 ⬇️

artículo científico publicado el 6 de julio de 1998

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

scientific journal article

Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans

artículo científico publicado en 2009

Bioactive long-term release from biodegradable microspheres preserves implanted ALG-PLO-ALG microcapsules from in vivo response to purified alginate

artículo científico publicado en 2009

CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.

artículo científico publicado en 2004

CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig.

artículo científico publicado en 2005

CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum− or helper peptides in priming for skin test reactivity to a P815AB‐related peptide ⬇️

artículo científico publicado el 1 de octubre de 1995

CTLA-4-Ig regulates tryptophan catabolism in vivo.

artículo científico publicado en 2002

Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice.

artículo científico publicado en 2014

Comparative proteomic analysis of two distinct stem-cell populations from human amniotic fluid

artículo científico publicado en 2015

CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis.

scientific article published on 05 March 2017

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

artículo científico publicado en 2015

Cytotoxic T lymphocyte antigen 4-immunoglobulin G is a potent adjuvant for experimental allergen immunotherapy

artículo científico publicado en 2013

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

artículo científico publicado en 2008

Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1in juvenile diabetes.

artículo científico publicado en 2018

Delineating the Role of Toll-Like Receptors in the Neuro-inflammation Model EAE.

artículo científico publicado en 2016

Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3+ regulatory T cells in humans and mice

artículo científico publicado en 2014

Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1.

scientific article published on 30 September 2016

Effects of a nutraceutical combination on lipids, inflammation and endothelial integrity in patients with subclinical inflammation: a randomized clinical trial

artículo científico publicado en 2016

Effects of intraperitoneal injection of microencapsulated Sertoli cells on chronic and presymptomatic dystrophic mice

artículo científico publicado en 2015

Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12.

artículo científico publicado en 2005

Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes

artículo científico publicado en 2014

Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc.

artículo científico publicado en 2007

Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor

artículo científico publicado en 2020

Generation of T cell regulatory activity by plasmacytoid dendritic cells and tryptophan catabolism.

artículo científico publicado en 2007

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction.

artículo científico publicado en 2010

High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway.

artículo científico publicado en 2013

IDO mediates TLR9-driven protection from experimental autoimmune diabetes.

artículo científico publicado en 2009

IDO1 Deficiency Does Not Affect Disease in Mouse Models of Systemic Juvenile Idiopathic Arthritis and Secondary Hemophagocytic Lymphohistiocytosis.

artículo científico publicado en 2016

IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII.

artículo científico publicado en 2015

IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi

artículo científico publicado en 2008

IL-22 defines a novel immune pathway of antifungal resistance.

artículo científico publicado en 2010

Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism

artículo científico publicado en 2006

Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes

artículo científico publicado en 2007

Improved efficacy of dendritic cell vaccines and successful immunization with tumor antigen peptide-pulsed peripheral blood mononuclear cells by coadministration of recombinant murine interleukin-12

artículo científico publicado en 1999

In vitro cadmium effects on ECM gene expression in human bronchial epithelial cells.

artículo científico publicado en 2014

Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines

artículo científico publicado en 2005

Indoleamine 2,3-dioxygenase (IDO) in inflammation and allergy to Aspergillus

artículo científico publicado en 2008

Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.

artículo científico publicado en 2014

Indoleamine 2,3-dioxygenase in infection: the paradox of an evasive strategy that benefits the host

artículo científico publicado en 2008

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

scientific journal article

Indoleamine 2,3‐dioxygenase: From catalyst to signaling function ⬇️

artículo científico publicado el 1 de agosto de 2012

Interaction of 7-Alkoxycoumarins with the Aryl Hydrocarbon Receptor.

artículo científico publicado en 2017

Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis.

artículo científico publicado en 2009

Intraperitoneal injection of microencapsulated Sertoli cells restores muscle morphology and performance in dystrophic mice

artículo científico publicado en 2015

Jack of all trades: thymosin α1 and its pleiotropy

artículo científico

LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism

artículo científico publicado en 2014

Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells.

artículo científico publicado en 2005

Ligand binding and functional selectivity of L-tryptophan metabolites at the mouse aryl hydrocarbon receptor (mAhR).

artículo científico publicado en 2014

Long-term stability, functional competence, and safety of microencapsulated specific pathogen-free neonatal porcine Sertoli cells: a potential product for cell transplant therapy

artículo científico publicado en 2015

Melanoma presenting as circulating tumor cells associated with failed angiogenesis

artículo científico publicado en 2008

Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation.

artículo científico publicado en 2010

Modulation of tryptophan catabolism by regulatory T cells.

artículo científico publicado en 2003

NEDD4 controls the expression of GUCD1, a protein upregulated in proliferating liver cells

artículo científico publicado en 2014

On-treatment C-reactive protein and HDL cholesterol levels in patients at intermediate cardiovascular risk: impact on carotid intima-media thickness

artículo científico publicado en 2013

PCSK9 at the crossroad of cholesterol metabolism and immune function during infections

artículo científico publicado en 2017

Prolongation of skin allograft survival in rats by the transplantation of microencapsulated xenogeneic neonatal porcine Sertoli cells.

artículo científico publicado en 2012

Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8+ Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3) ⬇️

artículo científico publicado el 10 de junio de 2010

Receptors and pathways in innate antifungal immunity: the implication for tolerance and immunity to fungi.

artículo científico publicado en 2007

Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

artículo científico publicado en 2007

Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1.

artículo científico publicado en 2016

Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1.

artículo científico publicado en 2015

T cell apoptosis by tryptophan catabolism

artículo científico publicado en 2002

TLR3 essentially promotes protective class I-restricted memory CD8⁺ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients

artículo científico publicado en 2011

TLRs govern neutrophil activity in aspergillosis

artículo científico publicado en 2004

Targeting Aryl hydrocarbon receptor for next-generation immunotherapies: Selective modulators (SAhRMs) versus rapidly metabolized ligands (RMAhRLs)

scientific article published on 02 November 2019

Targeting metabotropic glutamate receptors in neuroimmune communication ⬇️

artículo científico publicado el 26 de mayo de 2012

Th17/Treg imbalance in murine cystic fibrosis is linked to indoleamine 2,3-dioxygenase deficiency but corrected by kynurenines.

artículo científico publicado en 2013

The 2004 FASEB Summer Research Conference on Transplant Immunology: closer to the goal of transplant-specific tolerance

artículo científico publicado en 2005

The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors.

artículo científico publicado en 2015

The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

artículo científico publicado en 2006

Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone.

artículo científico publicado en 2009

Thymosin 1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance

scientific article published on 01 June 2006

Thymosin alpha1: the regulator of regulators?

artículo científico publicado en 2010

Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis

artículo científico publicado en 2017

Tolerance, DCs and tryptophan: much ado about IDO

artículo científico publicado en 2003

Toll-like receptor 9-mediated induction of the immunosuppressive pathway of tryptophan catabolism.

artículo científico publicado en 2006

Toll-like receptors as novel therapeutic targets for herpes simplex virus infection

scientific article published on 02 July 2019

Topical application of soluble CD83 induces IDO-mediated immune modulation, increases Foxp3+ T cells, and prolongs allogeneic corneal graft survival

artículo científico publicado en 2013

Toward the identification of a tolerogenic signature in IDO-competent dendritic cells.

artículo científico publicado en 2005

Tryptophan Feeding of the IDO1-AhR Axis in Host-Microbial Symbiosis

artículo científico

Tryptophan catabolism generates autoimmune-preventive regulatory T cells

artículo científico publicado en 2006

Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22.

artículo científico publicado en 2013

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

scientific article published on 01 May 2019

Xenograft of microencapsulated Sertoli cells restores glucose homeostasis in db/db mice with spontaneous diabetes mellitus

artículo científico publicado en 2016

Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells

artículo científico publicado en 2010

Lista de obras de Francesca Fallarino

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression

A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells

A crucial role for tryptophan catabolism at the host/Candida albicans interface.

A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice

Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers

AhR-Mediated, Non-Genomic Modulation of IDO1 Function

AhR: far more than an environmental sensor

Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells

Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

Antigen-specific regression of established tumors induced by active immunization with irradiated IL-12- but not B7-1-transfected tumor cells ⬇️

Aryl Hydrocarbon Receptor-Dependent Pathways in Immune Regulation.

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype

B7-1 Engagement of Cytotoxic T Lymphocyte Antigen 4 Inhibits T Cell Activation in the Absence of CD28 ⬇️

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans

Bioactive long-term release from biodegradable microspheres preserves implanted ALG-PLO-ALG microcapsules from in vivo response to purified alginate

CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.

CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig.

CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum− or helper peptides in priming for skin test reactivity to a P815AB‐related peptide ⬇️

CTLA-4-Ig regulates tryptophan catabolism in vivo.

Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice.

Comparative proteomic analysis of two distinct stem-cell populations from human amniotic fluid

CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis.

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

Cytotoxic T lymphocyte antigen 4-immunoglobulin G is a potent adjuvant for experimental allergen immunotherapy

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1in juvenile diabetes.

Delineating the Role of Toll-Like Receptors in the Neuro-inflammation Model EAE.

Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3+ regulatory T cells in humans and mice

Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1.

Effects of a nutraceutical combination on lipids, inflammation and endothelial integrity in patients with subclinical inflammation: a randomized clinical trial

Effects of intraperitoneal injection of microencapsulated Sertoli cells on chronic and presymptomatic dystrophic mice

Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12.

Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes

Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc.

Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor

Generation of T cell regulatory activity by plasmacytoid dendritic cells and tryptophan catabolism.

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction.

High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway.

IDO mediates TLR9-driven protection from experimental autoimmune diabetes.

IDO1 Deficiency Does Not Affect Disease in Mouse Models of Systemic Juvenile Idiopathic Arthritis and Secondary Hemophagocytic Lymphohistiocytosis.

IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII.

IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi

IL-22 defines a novel immune pathway of antifungal resistance.

Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism

Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes

Improved efficacy of dendritic cell vaccines and successful immunization with tumor antigen peptide-pulsed peripheral blood mononuclear cells by coadministration of recombinant murine interleukin-12

In vitro cadmium effects on ECM gene expression in human bronchial epithelial cells.

Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines

Indoleamine 2,3-dioxygenase (IDO) in inflammation and allergy to Aspergillus

Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.

Indoleamine 2,3-dioxygenase in infection: the paradox of an evasive strategy that benefits the host

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

Indoleamine 2,3‐dioxygenase: From catalyst to signaling function ⬇️

Interaction of 7-Alkoxycoumarins with the Aryl Hydrocarbon Receptor.

Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis.

Intraperitoneal injection of microencapsulated Sertoli cells restores muscle morphology and performance in dystrophic mice

Jack of all trades: thymosin α1 and its pleiotropy

LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism

Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells.

Ligand binding and functional selectivity of L-tryptophan metabolites at the mouse aryl hydrocarbon receptor (mAhR).

Long-term stability, functional competence, and safety of microencapsulated specific pathogen-free neonatal porcine Sertoli cells: a potential product for cell transplant therapy

Melanoma presenting as circulating tumor cells associated with failed angiogenesis

Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation.

Modulation of tryptophan catabolism by regulatory T cells.

NEDD4 controls the expression of GUCD1, a protein upregulated in proliferating liver cells

On-treatment C-reactive protein and HDL cholesterol levels in patients at intermediate cardiovascular risk: impact on carotid intima-media thickness

PCSK9 at the crossroad of cholesterol metabolism and immune function during infections

Prolongation of skin allograft survival in rats by the transplantation of microencapsulated xenogeneic neonatal porcine Sertoli cells.

Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8+ Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3) ⬇️

Receptors and pathways in innate antifungal immunity: the implication for tolerance and immunity to fungi.

Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1.

Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1.

T cell apoptosis by tryptophan catabolism

TLR3 essentially promotes protective class I-restricted memory CD8⁺ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients

TLRs govern neutrophil activity in aspergillosis