Lista de obras - Erica Salvati - Dominio Público Uruguay

A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

artículo científico publicado en 2015

A bimodal fluorescent and photocytotoxic naphthalene diimide for theranostic applications

artículo científico publicado en 2016

Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells

artículo científico publicado en 2012

BRCA2 Deletion Induces Alternative Lengthening of Telomeres in Telomerase Positive Colon Cancer Cells

artículo científico publicado en 2019

Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis

scholarly article

DNA Damage Persistence as Determinant of Tumor Sensitivity to the Combination of Topo I Inhibitors and Telomere-Targeting Agents

artículo científico publicado en 2011

Diagnosis and treatment of ALT tumors: is Trabectedin a new therapeutic option?

artículo científico publicado en 2017

Dyads of G-Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration

scientific article published on 01 August 2019

Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

artículo científico publicado en 2015

Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis

artículo científico publicado en 2013

Evidence for G-quadruplex in the promoter of VEGFR-2 and its targeting to inhibit tumor angiogenesis.

artículo científico publicado en 2014

Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence

artículo científico publicado en 2013

Fine regulation of RhoA and Rock is required for skeletal muscle differentiation

artículo científico publicado en 2006

G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells

scientific article published on 13 March 2020

G-quadruplex ligand RHPS4 potentiates the antitumor activity of camptothecins in preclinical models of solid tumors.

artículo científico publicado en 2008

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

artículo científico publicado en 2014

Identification of novel interactors of human telomeric G-quadruplex DNA

Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance

artículo científico publicado en 2015

Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment.

artículo científico publicado en 2017

Methods of studying telomere damage induced by quadruplex-ligand complexes ⬇️

artículo científico publicado el 4 de marzo de 2012

N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage

artículo científico publicado en 2011

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

scientific article published on 19 September 2013

PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment

artículo científico publicado en 2023

PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy

artículo científico publicado en 2010

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.

artículo científico publicado en 2016

Shading the TRF2 Recruiting Function: A New Horizon in Drug Development

article

Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway

artículo científico publicado en 2009

TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage

artículo científico publicado en 2010

TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells

artículo científico publicado en 2013

Targeting G-Quadruplex DNA Structures by EMICORON Has a Strong Antitumor Efficacy against Advanced Models of Human Colon Cancer

artículo científico publicado en 2015

Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect

artículo científico publicado en 2007

p120 Catenin is required for growth factor-dependent cell motility and scattering in epithelial cells

artículo científico publicado en 2003

β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling.

artículo científico publicado en 2012

Lista de obras de Erica Salvati

A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

A bimodal fluorescent and photocytotoxic naphthalene diimide for theranostic applications

Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells

BRCA2 Deletion Induces Alternative Lengthening of Telomeres in Telomerase Positive Colon Cancer Cells

Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis

DNA Damage Persistence as Determinant of Tumor Sensitivity to the Combination of Topo I Inhibitors and Telomere-Targeting Agents

Diagnosis and treatment of ALT tumors: is Trabectedin a new therapeutic option?

Dyads of G-Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration

Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis

Evidence for G-quadruplex in the promoter of VEGFR-2 and its targeting to inhibit tumor angiogenesis.

Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence

Fine regulation of RhoA and Rock is required for skeletal muscle differentiation

G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells

G-quadruplex ligand RHPS4 potentiates the antitumor activity of camptothecins in preclinical models of solid tumors.

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

Identification of novel interactors of human telomeric G-quadruplex DNA

Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance

Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment.

Methods of studying telomere damage induced by quadruplex-ligand complexes ⬇️

N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment

PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.

Shading the TRF2 Recruiting Function: A New Horizon in Drug Development

Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway

TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage

TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells

Targeting G-Quadruplex DNA Structures by EMICORON Has a Strong Antitumor Efficacy against Advanced Models of Human Colon Cancer

Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect

p120 Catenin is required for growth factor-dependent cell motility and scattering in epithelial cells

β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling.