Lista de obras - Didier Boturyn - Dominio Público Uruguay

"Polymultivalent" Polymer-Peptide Cluster Conjugates for an Enhanced Targeting of Cells Expressing αvβ3 Integrins.

artículo científico publicado en 2017

1-Ethoxyethylidene, a new group for the stepwise SPPS of aminooxyacetic acid containing peptides.

artículo científico publicado en 2008

67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice

artículo científico publicado en 2017

A gadolinium-binding cyclodecapeptide with a large high-field relaxivity involving second-sphere water

artículo científico publicado en 2009

A quartz crystal microbalance method to study the terminal functionalization of glycosaminoglycans

article

Activatable fluorescent probes for tumour-targeting imaging in live mice

artículo científico publicado en 2006

Activatable probes for non-invasive small animal fluorescence imaging

Antimicrobial Peptides as Probes in Biosensors Detecting Whole Bacteria: A Review

scientific article published on 24 April 2020

Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.

artículo científico publicado en 2010

Binding of the chemokine CXCL12α to its natural extracellular matrix ligand heparan sulfate enables myoblast adhesion and facilitates cell motility ⬇️

artículo científico publicado en 2017

Biomolecular assemblies combining two orthogonal copper-mediated ligations in a one-pot reaction

artículo científico publicado en 2015

Biomolecular assembly by iterative oxime ligations

scientific article published on 28 March 2009

Cell adhesion through clustered ligand on fluid supported lipid bilayers

artículo científico publicado en 2010

Chemical and biological evaluations of an (111)in-labeled RGD-peptide targeting integrin alpha(V) beta(3) in a preclinical tumor model.

artículo científico publicado en 2008

Chemoselectively addressable template: a valuable tool for the engineering of molecular conjugates

artículo científico publicado en 2006

Clustering and internalization of integrin alphavbeta3 with a tetrameric RGD-synthetic peptide.

scientific article published on 03 March 2009

Cyclodecapeptides to mimic the radical site of tyrosyl-containing proteins

scholarly article by Mohammed Akhter Hossain published in January 2006

Design of RGD-ATWLPPR peptide conjugates for the dual targeting of αVβ3 integrin and neuropilin-1

artículo científico publicado en 2018

Development of a selective cell capture and release assay: impact of clustered RGD ligands ⬇️

article

Drug development in oncology assisted by noninvasive optical imaging.

artículo científico publicado en 2009

From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence

artículo científico publicado en 2016

Highly efficient cell adhesion on beads functionalized with clustered peptide ligands

artículo científico publicado en 2009

Highly efficient synthesis of peptide- and carbohydrate-oligonucleotide conjugates using chemoselective oxime and thiazolidine formation

artículo científico publicado en 2003

Impact of Antigen Density on Recognition by Monoclonal Antibodies

artículo científico publicado en 2020

In Vivo Noninvasive Optical Imaging of Receptor-Mediated RGD Internalization Using Self-Quenched Cy5-Labeled RAFT-c(-RGDfK-) 4

scholarly article by Zhao-Hui Jin et al published January 2007 in Molecular imaging : official journal of the Society for Molecular Imaging

In vivo imaging of tumour angiogenesis in mice with the alpha(v)beta (3) integrin-targeted tracer 99mTc-RAFT-RGD.

artículo científico publicado en 2007

In vivo molecular imaging of myocardial angiogenesis using the αvβ3 integrin-targeted tracer 99mTc-RAFT-RGD

artículo científico publicado en 2010

In vivo optical imaging of integrin alphaV-beta3 in mice using multivalent or monovalent cRGD targeting vectors.

artículo científico publicado en 2007

Influence of Pre-organised Architecture on Cell Adhesion by Using Multivalent RGD Compounds

artículo científico publicado en 2016

Influence of the Spatial Conformation of Charged Ligands on the Optical Properties of Gold Nanoclusters

artículo científico publicado en 2019

Inhibition of the ferric uptake regulator by peptides derived from anti-FUR peptide aptamers: coupled theoretical and experimental approaches

artículo científico publicado en 2014

Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate

artículo científico publicado en 2012

Luminescent Zinc Fingers: Zn-Responsive Neodymium Near-Infrared Emission in Water.

artículo científico publicado en 2017

Luminescent probes for optical in vivo imaging

Mercury Trithiolate Binding (HgS3) to a de Novo Designed Cyclic Decapeptide with Three Preoriented Cysteine Side Chains.

artículo científico publicado en 2018

Micro-positron emission tomography/contrast-enhanced computed tomography imaging of orthotopic pancreatic tumor-bearing mice using the αvβ₃ integrin tracer ⁶⁴Cu-labeled cyclam-RAFT-c(-RGDfK-)₄.

artículo científico publicado en 2013

Model peptides based on the binding loop of the copper metallochaperone Atx1: selectivity of the consensus sequence MxCxxC for metal ions Hg(II), Cu(I), Cd(II), Pb(II), and Zn(II)

artículo científico publicado en 2006

Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-p

artículo científico publicado en 2007

Multivalent RGD synthetic peptides as potent alphaVbeta3 integrin ligands.

artículo científico publicado en 2006

Near-infrared optical guided surgery of highly infiltrative fibrosarcomas in cats using an anti-αvß3 integrin molecular probe.

artículo científico publicado en 2012

New multifunctional molecular conjugate vector for targeting, imaging, and therapy of tumors

artículo científico publicado en 2005

Noninvasive visualization and quantification of tumor αVβ3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4.

artículo científico publicado en 2011

Novel model peptide for Atx1-like metallochaperones.

artículo científico publicado en 2004

One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations.

artículo científico publicado en 2009

Oxime ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs.

artículo científico

PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of ⁶⁴Cu-cyclam-RAFT-c(-RGDfK-)₄ in vivo

artículo científico publicado en 2013

Photoactivated DNA cleavage by compounds structurally related to the bithiazole moiety of bleomycin

artículo científico publicado en 2001

Positron emission tomography of cerebral angiogenesis and TSPO expression in a mouse model of chronic hypoxia.

artículo científico publicado en 2017

Preparation of Peptide and Other Biomolecular Conjugates Through Chemoselective Ligations

artículo científico publicado en 2011

RGD-cyclam conjugate: synthesis and potential application for positron emission tomography.

artículo científico publicado en 2010

Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer

scientific article published on 15 September 2020

Redox strategy for reversible attachment of biomolecules using bifunctional linkers

artículo científico publicado en 2011

Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template

artículo científico publicado en 2006

Redox-driven host-guest interactions allow the controlled release of captured cells on RGD-functionalized surfaces

artículo científico publicado en 2014

Reduction of renal uptake of 111In-DOTA-labeled and A700-labeled RAFT-RGD during integrin αvβ3 targeting using single photon emission computed tomography and optical imaging

artículo científico publicado en 2012

Synthesis and Biological Characterization of Monomeric and Tetrameric RGD-Cryptophycin Conjugates

scientific article published on 11 February 2020

Synthesis and biological characterisation of targeted pro-apoptotic peptide.

artículo científico publicado en 2008

Synthesis and photophysical studies of a multivalent photoreactive Ru-calix[4]arene complex bearing RGD-containing cyclopentapeptides

article

Synthesis by native chemical ligation and characterization of the scorpion toxin AmmTx3

artículo científico publicado en 2018

Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model.

artículo científico publicado en 2017

Targeted delivery of a proapoptotic peptide to tumors in vivo.

artículo científico publicado en 2010

Targeted delivery of activatable fluorescent pro-apoptotic peptide into live cells

scientific article published on 17 November 2008

Targeted radionuclide therapy with RAFT-RGD radiolabelled with (90)Y or (177)Lu in a mouse model of αvβ3-expressing tumours.

artículo científico publicado en 2014

Template assembled cyclopeptides as multimeric system for integrin targeting and endocytosis

artículo científico publicado en 2004

Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model.

artículo científico publicado en 2018

αVβ3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.

artículo científico publicado en 2016

Lista de obras de Didier Boturyn

"Polymultivalent" Polymer-Peptide Cluster Conjugates for an Enhanced Targeting of Cells Expressing αvβ3 Integrins.

1-Ethoxyethylidene, a new group for the stepwise SPPS of aminooxyacetic acid containing peptides.

67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice

A gadolinium-binding cyclodecapeptide with a large high-field relaxivity involving second-sphere water

A quartz crystal microbalance method to study the terminal functionalization of glycosaminoglycans

Activatable fluorescent probes for tumour-targeting imaging in live mice

Activatable probes for non-invasive small animal fluorescence imaging

Antimicrobial Peptides as Probes in Biosensors Detecting Whole Bacteria: A Review

Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.

Binding of the chemokine CXCL12α to its natural extracellular matrix ligand heparan sulfate enables myoblast adhesion and facilitates cell motility ⬇️

Biomolecular assemblies combining two orthogonal copper-mediated ligations in a one-pot reaction

Biomolecular assembly by iterative oxime ligations

Cell adhesion through clustered ligand on fluid supported lipid bilayers

Chemical and biological evaluations of an (111)in-labeled RGD-peptide targeting integrin alpha(V) beta(3) in a preclinical tumor model.

Chemoselectively addressable template: a valuable tool for the engineering of molecular conjugates

Clustering and internalization of integrin alphavbeta3 with a tetrameric RGD-synthetic peptide.

Cyclodecapeptides to mimic the radical site of tyrosyl-containing proteins

Design of RGD-ATWLPPR peptide conjugates for the dual targeting of αVβ3 integrin and neuropilin-1

Development of a selective cell capture and release assay: impact of clustered RGD ligands ⬇️

Drug development in oncology assisted by noninvasive optical imaging.

From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence

Highly efficient cell adhesion on beads functionalized with clustered peptide ligands

Highly efficient synthesis of peptide- and carbohydrate-oligonucleotide conjugates using chemoselective oxime and thiazolidine formation

Impact of Antigen Density on Recognition by Monoclonal Antibodies

In Vivo Noninvasive Optical Imaging of Receptor-Mediated RGD Internalization Using Self-Quenched Cy5-Labeled RAFT-c(-RGDfK-) 4

In vivo imaging of tumour angiogenesis in mice with the alpha(v)beta (3) integrin-targeted tracer 99mTc-RAFT-RGD.

In vivo molecular imaging of myocardial angiogenesis using the αvβ3 integrin-targeted tracer 99mTc-RAFT-RGD

In vivo optical imaging of integrin alphaV-beta3 in mice using multivalent or monovalent cRGD targeting vectors.

Influence of Pre-organised Architecture on Cell Adhesion by Using Multivalent RGD Compounds

Influence of the Spatial Conformation of Charged Ligands on the Optical Properties of Gold Nanoclusters

Inhibition of the ferric uptake regulator by peptides derived from anti-FUR peptide aptamers: coupled theoretical and experimental approaches

Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate

Luminescent Zinc Fingers: Zn-Responsive Neodymium Near-Infrared Emission in Water.

Luminescent probes for optical in vivo imaging

Mercury Trithiolate Binding (HgS3) to a de Novo Designed Cyclic Decapeptide with Three Preoriented Cysteine Side Chains.

Micro-positron emission tomography/contrast-enhanced computed tomography imaging of orthotopic pancreatic tumor-bearing mice using the αvβ₃ integrin tracer ⁶⁴Cu-labeled cyclam-RAFT-c(-RGDfK-)₄.

Model peptides based on the binding loop of the copper metallochaperone Atx1: selectivity of the consensus sequence MxCxxC for metal ions Hg(II), Cu(I), Cd(II), Pb(II), and Zn(II)

Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-p

Multivalent RGD synthetic peptides as potent alphaVbeta3 integrin ligands.

Near-infrared optical guided surgery of highly infiltrative fibrosarcomas in cats using an anti-αvß3 integrin molecular probe.

New multifunctional molecular conjugate vector for targeting, imaging, and therapy of tumors

Noninvasive visualization and quantification of tumor αVβ3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4.

Novel model peptide for Atx1-like metallochaperones.

One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations.

Oxime ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs.

PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of ⁶⁴Cu-cyclam-RAFT-c(-RGDfK-)₄ in vivo

Photoactivated DNA cleavage by compounds structurally related to the bithiazole moiety of bleomycin

Positron emission tomography of cerebral angiogenesis and TSPO expression in a mouse model of chronic hypoxia.

Preparation of Peptide and Other Biomolecular Conjugates Through Chemoselective Ligations

RGD-cyclam conjugate: synthesis and potential application for positron emission tomography.

Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer

Redox strategy for reversible attachment of biomolecules using bifunctional linkers

Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template

Redox-driven host-guest interactions allow the controlled release of captured cells on RGD-functionalized surfaces

Reduction of renal uptake of 111In-DOTA-labeled and A700-labeled RAFT-RGD during integrin αvβ3 targeting using single photon emission computed tomography and optical imaging

Synthesis and Biological Characterization of Monomeric and Tetrameric RGD-Cryptophycin Conjugates

Synthesis and biological characterisation of targeted pro-apoptotic peptide.

Synthesis and photophysical studies of a multivalent photoreactive Ru-calix[4]arene complex bearing RGD-containing cyclopentapeptides

Synthesis by native chemical ligation and characterization of the scorpion toxin AmmTx3

Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model.

Targeted delivery of a proapoptotic peptide to tumors in vivo.

Targeted delivery of activatable fluorescent pro-apoptotic peptide into live cells

Targeted radionuclide therapy with RAFT-RGD radiolabelled with (90)Y or (177)Lu in a mouse model of αvβ3-expressing tumours.

Template assembled cyclopeptides as multimeric system for integrin targeting and endocytosis

Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model.

αVβ3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.