Lista de obras - Blake R. Peterson - Dominio Público Uruguay

11beta-alkyl-Delta9-19-nortestosterone derivatives: high-affinity ligands and potent partial agonists of the androgen receptor

artículo científico publicado en 2004

A concise synthesis of the Pennsylvania Green fluorophore and labeling of intracellular targets with O6-benzylguanine derivatives

artículo científico publicado en 2007

A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1

artículo científico publicado en 1996

A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity

artículo científico publicado en 2002

A synthetic membrane-anchored antigen efficiently promotes uptake of antifluorescein antibodies and associated protein a by mammalian cells.

artículo científico publicado en 2001

A synthetic mimic of human Fc receptors: defined chemical modification of cell surfaces enables efficient endocytic uptake of human immunoglobulin-G.

artículo científico publicado en 2006

An amphotericin B-fluorescein conjugate as a powerful probe for biochemical studies of the membrane

artículo científico publicado en 2004

Analysis of protein tyrosine kinase inhibitors in recombinant yeast lacking the ERG6 gene

artículo científico publicado en 2003

Antibacterial and hemolytic activities of pyridinium polymers as a function of the spatial relationship between the positive charge and the pendant alkyl tail

artículo científico publicado en 2008

Antibody-Drug Conjugate that Exhibits Synergistic Cytotoxicity with an Endosome-Disruptive Peptide

scientific article published on 31 July 2019

Anticancer/antiviral agent Akt inhibitor-IV massively accumulates in mitochondria and potently disrupts cellular bioenergetics.

artículo científico publicado en 2014

Augmenting vitamin D to combat genetic disease.

artículo científico publicado en 2002

Calcium flux in neuroblastoma cells is a coupling mechanism between non-genomic and genomic modes of estrogens.

artículo científico publicado en 2005

Cavity depth and width effects on cyclophane-steroid recognition: molecular complexation of cholesterol and progesterone in aqueous solution.

artículo científico publicado en 1995

Chemico-genetic identification of drebrin as a regulator of calcium responses

artículo científico publicado en 2009

Control of gene expression with small molecules: biotin-mediated acylation of targeted lysine residues in recombinant yeast

artículo científico publicado en 2003

Detection of protein-protein interactions by proximity-driven S(N)Ar reactions of lysine-linked fluorophores

artículo científico publicado en 2014

Development of a cell-based, high-throughput screening assay for cholesterol efflux using a fluorescent mimic of cholesterol

artículo científico publicado en 2010

Efficient and Scalable Synthesis of 4-Carboxy-Pennsylvania Green Methyl Ester: A Hydrophobic Building Block for Fluorescent Molecular Probes

artículo científico publicado en 2014

Efficient delivery of streptavidin to mammalian cells: clathrin-mediated endocytosis regulated by a synthetic ligand

artículo científico publicado en 2002

Endocytic delivery of vancomycin mediated by a synthetic cell surface receptor: rescue of bacterially infected Mammalian cells and tissue targeting in vivo

artículo científico publicado en 2007

Facile synthesis of cids: biotinylated estrone oximes efficiently heterodimerize estrogen receptor and streptavidin proteins in yeast three hybrid systems

artículo científico publicado en 2004

Fluorescence-based cloning of a protein tyrosine kinase with a yeast tribrid system

artículo científico publicado en 2005

Fluorescent cellular sensors of steroid receptor ligands

artículo científico publicado en 2003

Fluorescent mimics of cholesterol that rapidly bind surfaces of living mammalian cells.

artículo científico publicado en 2015

Human neutrophil peptides mediate endothelial-monocyte interaction, foam cell formation, and platelet activation.

artículo científico publicado en 2011

Hydrophobic resorufamine derivatives: potent and selective red fluorescent probes of the endoplasmic reticulum of mammalian cells

artículo científico publicado en 2016

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry

artículo científico publicado en 2012

Interaction of 3β-amino-5-cholestene with phospholipids in binary and ternary bilayer membranes

artículo científico publicado en 2011

Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.

artículo científico publicado en 2008

Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.

artículo científico publicado en 2007

Molecule-specific imaging with mass spectrometry and a buckminsterfullerene probe: application to characterizing solid-phase synthesized combinatorial libraries

artículo científico publicado en 2004

Multifunctional silane polymers for persistent surface derivatization and their antimicrobial properties.

artículo científico publicado en 2008

Non-natural cell surface receptors: synthetic peptides capped with N-cholesterylglycine efficiently deliver proteins into Mammalian cells

artículo científico publicado en 2003

Novel acid-activated fluorophores reveal a dynamic wave of protons in the intestine of Caenorhabditis elegans

artículo científico publicado en 2013

Practical synthesis of 3beta-amino-5-cholestene and related 3beta-halides involving i-steroid and retro-i-steroid rearrangements

artículo científico publicado en 2009

Quantification of Small Molecule-Protein Interactions using FRET between Tryptophan and the Pacific Blue Fluorophore.

artículo científico publicado en 2016

Rapid detection of protein tyrosine kinase activity in recombinant yeast expressing a universal substrate.

artículo científico publicado en 2002

Selective disruption of early/recycling endosomes: release of disulfide-linked cargo mediated by a N-alkyl-3beta-cholesterylamine-capped peptide

artículo científico publicado en 2008

Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides

artículo científico publicado en 2012

Silver bromide nanoparticle/polymer composites: dual action tunable antimicrobial materials.

artículo científico publicado en 2006

Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity

artículo científico publicado en 2019

Small-molecule triggers of tadpole metamorphosis.

artículo científico publicado en 2006

Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase

artículo científico publicado en 2008

Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2.

artículo científico publicado en 2011

Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.

artículo científico publicado en 2006

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

artículo científico publicado en 2002

Synthesis and biological evaluation of analogues of AKT (protein kinase B) inhibitor-IV.

artículo científico publicado en 2011

Synthesis of Fluorophores that Target Small Molecules to the Endoplasmic Reticulum of Living Mammalian Cells

artículo científico publicado en 2015

Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses

artículo científico publicado en 2010

Synthesis of a Fluorescent Analogue of Paclitaxel That Selectively Binds Microtubules and Sensitively Detects Efflux by P-Glycoprotein

artículo científico publicado en 2017

Synthesis of a beta-estradiol-biotin chimera that potently heterodimerizes estrogen receptor and streptavidin proteins in a yeast three-hybrid system.

artículo científico publicado en 2003

Synthesis of a high-affinity fluorescent PPARgamma ligand for high-throughput fluorescence polarization assays

artículo científico publicado en 2003

Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase

artículo científico publicado en 2007

Synthesis of an artificial cell surface receptor that enables oligohistidine affinity tags to function as metal-dependent cell-penetrating peptides

artículo científico publicado en 2006

Synthesis of chimeric 7alpha-substituted estradiol derivatives linked to cholesterol and cholesterylamine.

artículo científico publicado en 2002

Synthesis of fluorinated benzophenones, xanthones, acridones, and thioxanthones by iterative nucleophilic aromatic substitution

artículo científico publicado en 2011

Synthetic cell surface receptors for delivery of therapeutics and probes ⬇️

artículo científico publicado el 25 de febrero de 2012

Synthetic mimics of small Mammalian cell surface receptors

artículo científico publicado en 2004

Targeting Fluorescent Sensors to Endoplasmic Reticulum Membranes Enables Detection of Peroxynitrite During Cellular Phagocytosis

artículo científico publicado en 2018

Targeting of Histone Acetyltransferase p300 by Cyclopentenone Prostaglandin Δ12-PGJ2 through Covalent Binding to Cys1438 ⬇️

artículo científico publicado el 16 de diciembre de 2011

The C. elegans CHP1 homolog, pbo-1, functions in innate immunity by regulating the pH of the intestinal lumen

scientific article published on 09 January 2020

The Pennsylvania Green Fluorophore: a hybrid of Oregon Green and Tokyo Green for the construction of hydrophobic and pH-insensitive molecular probes.

artículo científico publicado en 2006

The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency.

artículo científico publicado en 1998

Lista de obras de Blake R. Peterson

11beta-alkyl-Delta9-19-nortestosterone derivatives: high-affinity ligands and potent partial agonists of the androgen receptor

A concise synthesis of the Pennsylvania Green fluorophore and labeling of intracellular targets with O6-benzylguanine derivatives

A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1

A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity

A synthetic membrane-anchored antigen efficiently promotes uptake of antifluorescein antibodies and associated protein a by mammalian cells.

A synthetic mimic of human Fc receptors: defined chemical modification of cell surfaces enables efficient endocytic uptake of human immunoglobulin-G.

An amphotericin B-fluorescein conjugate as a powerful probe for biochemical studies of the membrane

Analysis of protein tyrosine kinase inhibitors in recombinant yeast lacking the ERG6 gene

Antibacterial and hemolytic activities of pyridinium polymers as a function of the spatial relationship between the positive charge and the pendant alkyl tail

Antibody-Drug Conjugate that Exhibits Synergistic Cytotoxicity with an Endosome-Disruptive Peptide

Anticancer/antiviral agent Akt inhibitor-IV massively accumulates in mitochondria and potently disrupts cellular bioenergetics.

Augmenting vitamin D to combat genetic disease.

Calcium flux in neuroblastoma cells is a coupling mechanism between non-genomic and genomic modes of estrogens.

Cavity depth and width effects on cyclophane-steroid recognition: molecular complexation of cholesterol and progesterone in aqueous solution.

Chemico-genetic identification of drebrin as a regulator of calcium responses

Control of gene expression with small molecules: biotin-mediated acylation of targeted lysine residues in recombinant yeast

Detection of protein-protein interactions by proximity-driven S(N)Ar reactions of lysine-linked fluorophores

Development of a cell-based, high-throughput screening assay for cholesterol efflux using a fluorescent mimic of cholesterol

Efficient and Scalable Synthesis of 4-Carboxy-Pennsylvania Green Methyl Ester: A Hydrophobic Building Block for Fluorescent Molecular Probes

Efficient delivery of streptavidin to mammalian cells: clathrin-mediated endocytosis regulated by a synthetic ligand

Endocytic delivery of vancomycin mediated by a synthetic cell surface receptor: rescue of bacterially infected Mammalian cells and tissue targeting in vivo

Facile synthesis of cids: biotinylated estrone oximes efficiently heterodimerize estrogen receptor and streptavidin proteins in yeast three hybrid systems

Fluorescence-based cloning of a protein tyrosine kinase with a yeast tribrid system

Fluorescent cellular sensors of steroid receptor ligands

Fluorescent mimics of cholesterol that rapidly bind surfaces of living mammalian cells.

Human neutrophil peptides mediate endothelial-monocyte interaction, foam cell formation, and platelet activation.

Hydrophobic resorufamine derivatives: potent and selective red fluorescent probes of the endoplasmic reticulum of mammalian cells

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry

Interaction of 3β-amino-5-cholestene with phospholipids in binary and ternary bilayer membranes

Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.

Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.

Molecule-specific imaging with mass spectrometry and a buckminsterfullerene probe: application to characterizing solid-phase synthesized combinatorial libraries

Multifunctional silane polymers for persistent surface derivatization and their antimicrobial properties.

Non-natural cell surface receptors: synthetic peptides capped with N-cholesterylglycine efficiently deliver proteins into Mammalian cells

Novel acid-activated fluorophores reveal a dynamic wave of protons in the intestine of Caenorhabditis elegans

Practical synthesis of 3beta-amino-5-cholestene and related 3beta-halides involving i-steroid and retro-i-steroid rearrangements

Quantification of Small Molecule-Protein Interactions using FRET between Tryptophan and the Pacific Blue Fluorophore.

Rapid detection of protein tyrosine kinase activity in recombinant yeast expressing a universal substrate.

Selective disruption of early/recycling endosomes: release of disulfide-linked cargo mediated by a N-alkyl-3beta-cholesterylamine-capped peptide

Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides

Silver bromide nanoparticle/polymer composites: dual action tunable antimicrobial materials.

Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity

Small-molecule triggers of tadpole metamorphosis.

Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase

Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2.

Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

Synthesis and biological evaluation of analogues of AKT (protein kinase B) inhibitor-IV.

Synthesis of Fluorophores that Target Small Molecules to the Endoplasmic Reticulum of Living Mammalian Cells

Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses

Synthesis of a Fluorescent Analogue of Paclitaxel That Selectively Binds Microtubules and Sensitively Detects Efflux by P-Glycoprotein

Synthesis of a beta-estradiol-biotin chimera that potently heterodimerizes estrogen receptor and streptavidin proteins in a yeast three-hybrid system.

Synthesis of a high-affinity fluorescent PPARgamma ligand for high-throughput fluorescence polarization assays

Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase

Synthesis of an artificial cell surface receptor that enables oligohistidine affinity tags to function as metal-dependent cell-penetrating peptides

Synthesis of chimeric 7alpha-substituted estradiol derivatives linked to cholesterol and cholesterylamine.

Synthesis of fluorinated benzophenones, xanthones, acridones, and thioxanthones by iterative nucleophilic aromatic substitution

Synthetic cell surface receptors for delivery of therapeutics and probes ⬇️

Synthetic mimics of small Mammalian cell surface receptors

Targeting Fluorescent Sensors to Endoplasmic Reticulum Membranes Enables Detection of Peroxynitrite During Cellular Phagocytosis

Targeting of Histone Acetyltransferase p300 by Cyclopentenone Prostaglandin Δ12-PGJ2 through Covalent Binding to Cys1438 ⬇️

The C. elegans CHP1 homolog, pbo-1, functions in innate immunity by regulating the pH of the intestinal lumen

The Pennsylvania Green Fluorophore: a hybrid of Oregon Green and Tokyo Green for the construction of hydrophobic and pH-insensitive molecular probes.

The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency.